Ketamine for mood disorders, anxiety, and suicidality in children and adolescents: a systematic review
AbstractMood disorders, anxiety, and suicidality in youth are increasing and rapid-acting treatments are urgently needed. One potential is ketamine or its enantiomer esketamine, which was FDA approved in 2019 to treat major depressive disorder with suicidality in adults. This systematic review evaluated the evidence for the clinical use of ketamine to treat mood disorders, anxiety, and suicidality in youth. The PRISMA guidelines were used, and a protocol registered prospectively (https://osf.io/9ucsg/). The literature search included Pubmed/MEDLINE, Ovid/MEDLINE, Scopus, CINAHL, PsychInfo, and Google Scholar. Trial registr...
Source: European Child and Adolescent Psychiatry - May 16, 2024 Category: Psychiatry Source Type: research
Model for predicting the recurrence of atrial fibrillation after monopolar or bipolar radiofrequency ablation in patients with AF and mitral valve disease
This study aimed to identify the risk factors for postoperative atrial fibrillation in patients with valvular atrial fibrillation, and establish predictive models of atrial fibrillation recurrence. (Source: Journal of Cardiothoracic Surgery)
Source: Journal of Cardiothoracic Surgery - May 16, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Wei Si, Peng Teng and Liang Ma Tags: Research Source Type: research
Study Underscores Need for Sustained Intervention for Schizophrenia, Other Psychotic Disorders
Few individuals with schizophrenia or other psychotic disorders were in remission or recovery 25 years after diagnosis, according to areport inAJP in Advance today. For individuals with schizophrenia spectrum disorders (schizophrenia, schizoaffective, and schizophreniform disorders), almost none experienced stable remission or recovery across 25 years.The “stability of symptoms across the follow-up period indicates that more effective treatments are needed to influence the course of remission and recovery for individuals with schizophrenia spectrum disorders and illuminates the need for sustained intervention and support...
Source: Psychiatr News - May 15, 2024 Category: Psychiatry Tags: American Journal of Psychiatry disease trajectory functioning psychosis recovery remission schizophrenia Stony Brook Source Type: research
The impact of pregnancy-related hormonal and physiological changes on antiseizure medications: expert perspective
Expert Rev Clin Pharmacol. 2024 May 15. doi: 10.1080/17512433.2024.2356617. Online ahead of print.ABSTRACTINTRODUCTION: Epilepsy is a disorder of recurrent, unprovoked seizures affecting approximately 15 million individuals of childbearing potential worldwide. Patients with epilepsy rely on regular daily therapy with antiseizure medications (ASMs). Furthermore, ASMs are also prescribed for other neuropsychiatric indications (e.g. bipolar disorder, pain, migraines) with over 2% of the pregnancies in the United States involving prenatal exposure to ASMs.AREAS COVERED: ASM concentrations are affected by hormonal and physiolog...
Source: Expert Review of Clinical Pharmacology - May 15, 2024 Category: Drugs & Pharmacology Authors: Denise Li Susannah Franco Page B Pennell Source Type: research
Electroconvulsive Therapy in Transgender and Gender Diverse Population: A Case Report and Review of Literature
CONCLUSION: There is limited literature on the safety and efficacy of ECT for TGD individuals receiving GAHT. More research is required to address mental health inequalities in this population and to support safe and effective gender affirming treatment modalities.PMID:38746078 | PMC:PMC11093682 | DOI:10.1155/2024/5552781 (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - May 15, 2024 Category: Psychiatry Authors: Lachlan Draper Ashis Vikas Subhash Das Suresh Yadav Frances Walker Ivona Bandilovska Source Type: research
The impact of pregnancy-related hormonal and physiological changes on antiseizure medications: expert perspective
Expert Rev Clin Pharmacol. 2024 May 15. doi: 10.1080/17512433.2024.2356617. Online ahead of print.ABSTRACTINTRODUCTION: Epilepsy is a disorder of recurrent, unprovoked seizures affecting approximately 15 million individuals of childbearing potential worldwide. Patients with epilepsy rely on regular daily therapy with antiseizure medications (ASMs). Furthermore, ASMs are also prescribed for other neuropsychiatric indications (e.g. bipolar disorder, pain, migraines) with over 2% of the pregnancies in the United States involving prenatal exposure to ASMs.AREAS COVERED: ASM concentrations are affected by hormonal and physiolog...
Source: Pharmacological Reviews - May 15, 2024 Category: Drugs & Pharmacology Authors: Denise Li Susannah Franco Page B Pennell Source Type: research
DRESS as a rare differential diagnosis in eosinophilia, skin rash and acute hepatitis
Z Gastroenterol. 2024 May 15. doi: 10.1055/a-2300-0620. Online ahead of print.ABSTRACTA 21-year-old female patient presented with fever, pharyngitis, lymphadenopathy and generalized exanthema that had started 2 weeks prior. Allergies were not known, the family and travel history were negative. Due to depression, Duloxetine had been taken for 1.5 years, and due to bipolar disorder, a treatment with Lamotrigine was started four weeks prior but was stopped because of increased transaminase levels. Laboratory findings on admission showed eosinophilia (1.327 /nl), lymphocytosis and acute hepatitis (GOT 428 U/l, GPT 438 U/l) wit...
Source: Zeitschrift fur Gastroenterologie - May 15, 2024 Category: Gastroenterology Authors: Daniela Prechal David Arntzen Lioba Klaas Maren Paulmann Maja Mockenhaupt Robert Thimme Marcus Schuchmann Source Type: research
Are the concepts of "chronic mania" in German-speaking psychiatry around 1900 early contributions to the disorder of the adult form of attention deficit hyperactivity disorder (ADHD)?
Nervenarzt. 2024 May 15. doi: 10.1007/s00115-024-01669-7. Online ahead of print.ABSTRACTThe adult form of attention deficit hyperactivity disorder (ADHD) has increasingly become a focus of adult psychiatry. Despite long-established diagnostic criteria and specific therapeutic approaches for the disorder, the common misconception that ADHD is a "fad" has persisted. Examining the history of psychiatry can make an educational contribution by showing that the adult form of ADHD is a continuously existing illness phenomenon. The present study examines the discussion of sometimes prominent authors about "chronic mania" in German...
Source: Der Nervenarzt - May 15, 2024 Category: Neurology Authors: Steffen M üller Maria Strau ß Holger Steinberg Source Type: research
The impact of pregnancy-related hormonal and physiological changes on antiseizure medications: expert perspective
Expert Rev Clin Pharmacol. 2024 May 15. doi: 10.1080/17512433.2024.2356617. Online ahead of print.ABSTRACTINTRODUCTION: Epilepsy is a disorder of recurrent, unprovoked seizures affecting approximately 15 million individuals of childbearing potential worldwide. Patients with epilepsy rely on regular daily therapy with antiseizure medications (ASMs). Furthermore, ASMs are also prescribed for other neuropsychiatric indications (e.g. bipolar disorder, pain, migraines) with over 2% of the pregnancies in the United States involving prenatal exposure to ASMs.AREAS COVERED: ASM concentrations are affected by hormonal and physiolog...
Source: Expert Review of Clinical Pharmacology - May 15, 2024 Category: Drugs & Pharmacology Authors: Denise Li Susannah Franco Page B Pennell Source Type: research
Electroconvulsive Therapy in Transgender and Gender Diverse Population: A Case Report and Review of Literature
CONCLUSION: There is limited literature on the safety and efficacy of ECT for TGD individuals receiving GAHT. More research is required to address mental health inequalities in this population and to support safe and effective gender affirming treatment modalities.PMID:38746078 | PMC:PMC11093682 | DOI:10.1155/2024/5552781 (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - May 15, 2024 Category: Psychiatry Authors: Lachlan Draper Ashis Vikas Subhash Das Suresh Yadav Frances Walker Ivona Bandilovska Source Type: research
DRESS as a rare differential diagnosis in eosinophilia, skin rash and acute hepatitis
Z Gastroenterol. 2024 May 15. doi: 10.1055/a-2300-0620. Online ahead of print.ABSTRACTA 21-year-old female patient presented with fever, pharyngitis, lymphadenopathy and generalized exanthema that had started 2 weeks prior. Allergies were not known, the family and travel history were negative. Due to depression, Duloxetine had been taken for 1.5 years, and due to bipolar disorder, a treatment with Lamotrigine was started four weeks prior but was stopped because of increased transaminase levels. Laboratory findings on admission showed eosinophilia (1.327 /nl), lymphocytosis and acute hepatitis (GOT 428 U/l, GPT 438 U/l) wit...
Source: Zeitschrift fur Gastroenterologie - May 15, 2024 Category: Gastroenterology Authors: Daniela Prechal David Arntzen Lioba Klaas Maren Paulmann Maja Mockenhaupt Robert Thimme Marcus Schuchmann Source Type: research
Electroconvulsive Therapy in Transgender and Gender Diverse Population: A Case Report and Review of Literature
CONCLUSION: There is limited literature on the safety and efficacy of ECT for TGD individuals receiving GAHT. More research is required to address mental health inequalities in this population and to support safe and effective gender affirming treatment modalities.PMID:38746078 | PMC:PMC11093682 | DOI:10.1155/2024/5552781 (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - May 15, 2024 Category: Psychiatry Authors: Lachlan Draper Ashis Vikas Subhash Das Suresh Yadav Frances Walker Ivona Bandilovska Source Type: research
