Velocity-compensated intravoxel incoherent motion of the human calf muscle
CONCLUSION: Velocity-compensated diffusion gradients significantly suppress the IVIM effect in the calf muscle, indicating that the ballistic limit is mostly reached, which is supported by the time dependence of the pseudo-diffusion coefficient.PMID:38688865 | DOI:10.1002/mrm.30059 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - April 30, 2024 Category: Radiology Authors: Christoph M Stuprich Martin Loh Johannes T Nemerth Armin M Nagel Michael Uder Frederik B Laun Source Type: research
Predictors of long-term mortality in older patients with hip fractures managed by hemiarthroplasty: a 10-year study based on a population registry in Saxony, Germany
CONCLUSIONS: In the present study based on data from the population registry from Saxony, Germany the 10-year mortality of older patients above 60 years of age managed with hemiarthroplasty for femoral neck fracture was 80%. Independent risk factors for increased long-term mortality were higher patient age, male gender, severe comorbidity, a history of cancer and in particular dementia. Perioperative factors did not affect long-term mortality.PMID:38689330 | PMC:PMC11061946 | DOI:10.1186/s13037-024-00398-9 (Source: Patient Safety in Surgery)
Source: Patient Safety in Surgery - April 30, 2024 Category: Surgery Authors: Johannes K M Fakler Philipp Pieroh Andreas H öch Andreas Roth Christian Kleber Markus L öffler Christoph E Heyde Samira Zeynalova Source Type: research
Predictors of long-term mortality in older patients with hip fractures managed by hemiarthroplasty: a 10-year study based on a population registry in Saxony, Germany
CONCLUSIONS: In the present study based on data from the population registry from Saxony, Germany the 10-year mortality of older patients above 60 years of age managed with hemiarthroplasty for femoral neck fracture was 80%. Independent risk factors for increased long-term mortality were higher patient age, male gender, severe comorbidity, a history of cancer and in particular dementia. Perioperative factors did not affect long-term mortality.PMID:38689330 | PMC:PMC11061946 | DOI:10.1186/s13037-024-00398-9 (Source: Patient Safety in Surgery)
Source: Patient Safety in Surgery - April 30, 2024 Category: Surgery Authors: Johannes K M Fakler Philipp Pieroh Andreas H öch Andreas Roth Christian Kleber Markus L öffler Christoph E Heyde Samira Zeynalova Source Type: research
Predictors of long-term mortality in older patients with hip fractures managed by hemiarthroplasty: a 10-year study based on a population registry in Saxony, Germany
CONCLUSIONS: In the present study based on data from the population registry from Saxony, Germany the 10-year mortality of older patients above 60 years of age managed with hemiarthroplasty for femoral neck fracture was 80%. Independent risk factors for increased long-term mortality were higher patient age, male gender, severe comorbidity, a history of cancer and in particular dementia. Perioperative factors did not affect long-term mortality.PMID:38689330 | PMC:PMC11061946 | DOI:10.1186/s13037-024-00398-9 (Source: Patient Safety in Surgery)
Source: Patient Safety in Surgery - April 30, 2024 Category: Surgery Authors: Johannes K M Fakler Philipp Pieroh Andreas H öch Andreas Roth Christian Kleber Markus L öffler Christoph E Heyde Samira Zeynalova Source Type: research
Predictors of long-term mortality in older patients with hip fractures managed by hemiarthroplasty: a 10-year study based on a population registry in Saxony, Germany
CONCLUSIONS: In the present study based on data from the population registry from Saxony, Germany the 10-year mortality of older patients above 60 years of age managed with hemiarthroplasty for femoral neck fracture was 80%. Independent risk factors for increased long-term mortality were higher patient age, male gender, severe comorbidity, a history of cancer and in particular dementia. Perioperative factors did not affect long-term mortality.PMID:38689330 | PMC:PMC11061946 | DOI:10.1186/s13037-024-00398-9 (Source: Patient Safety in Surgery)
Source: Patient Safety in Surgery - April 30, 2024 Category: Surgery Authors: Johannes K M Fakler Philipp Pieroh Andreas H öch Andreas Roth Christian Kleber Markus L öffler Christoph E Heyde Samira Zeynalova Source Type: research
Predictors of long-term mortality in older patients with hip fractures managed by hemiarthroplasty: a 10-year study based on a population registry in Saxony, Germany
CONCLUSIONS: In the present study based on data from the population registry from Saxony, Germany the 10-year mortality of older patients above 60 years of age managed with hemiarthroplasty for femoral neck fracture was 80%. Independent risk factors for increased long-term mortality were higher patient age, male gender, severe comorbidity, a history of cancer and in particular dementia. Perioperative factors did not affect long-term mortality.PMID:38689330 | PMC:PMC11061946 | DOI:10.1186/s13037-024-00398-9 (Source: Patient Safety in Surgery)
Source: Patient Safety in Surgery - April 30, 2024 Category: Surgery Authors: Johannes K M Fakler Philipp Pieroh Andreas H öch Andreas Roth Christian Kleber Markus L öffler Christoph E Heyde Samira Zeynalova Source Type: research
Predictors of long-term mortality in older patients with hip fractures managed by hemiarthroplasty: a 10-year study based on a population registry in Saxony, Germany
CONCLUSIONS: In the present study based on data from the population registry from Saxony, Germany the 10-year mortality of older patients above 60 years of age managed with hemiarthroplasty for femoral neck fracture was 80%. Independent risk factors for increased long-term mortality were higher patient age, male gender, severe comorbidity, a history of cancer and in particular dementia. Perioperative factors did not affect long-term mortality.PMID:38689330 | PMC:PMC11061946 | DOI:10.1186/s13037-024-00398-9 (Source: Patient Safety in Surgery)
Source: Patient Safety in Surgery - April 30, 2024 Category: Surgery Authors: Johannes K M Fakler Philipp Pieroh Andreas H öch Andreas Roth Christian Kleber Markus L öffler Christoph E Heyde Samira Zeynalova Source Type: research
Predictors of long-term mortality in older patients with hip fractures managed by hemiarthroplasty: a 10-year study based on a population registry in Saxony, Germany
CONCLUSIONS: In the present study based on data from the population registry from Saxony, Germany the 10-year mortality of older patients above 60 years of age managed with hemiarthroplasty for femoral neck fracture was 80%. Independent risk factors for increased long-term mortality were higher patient age, male gender, severe comorbidity, a history of cancer and in particular dementia. Perioperative factors did not affect long-term mortality.PMID:38689330 | PMC:PMC11061946 | DOI:10.1186/s13037-024-00398-9 (Source: Patient Safety in Surgery)
Source: Patient Safety in Surgery - April 30, 2024 Category: Surgery Authors: Johannes K M Fakler Philipp Pieroh Andreas H öch Andreas Roth Christian Kleber Markus L öffler Christoph E Heyde Samira Zeynalova Source Type: research
Content analysis of Reddit posts about coadministration of selective serotonin reuptake inhibitors and psilocybin mushrooms
ConclusionsPsilocybin ’s interactions with SSRIs are likely complex and may depend on multiple factors. Prospective studies are needed to evaluate whether psilocybin treatments are reliably safe and effective in the setting of SSRI use. (Source: Psychopharmacology)
Source: Psychopharmacology - April 30, 2024 Category: Psychiatry Source Type: research
Understanding the Causal Relationships Between Opioid Dependence and Risk of Mental Disorders: A Comprehensive Two-Sample Mendelian Randomization Study
In this study, we aim to investigate the causal associations and possible mediating mechanisms between opioid dependence and mental disorders via Mendelian randomization. Comprehensive bidirectional Mendelian randomization (MR) studies were conducted between opioid dependence and major mental disorders, including schizophrenia, bipolar disorder, major depressive disorder, panic disorder, anorexia, obsessive –compulsive disorder, post-traumatic stress disorder, and insomnia. Inverse variance weighted approach was adopted as the primary analytic method with series of sensitivity analyses. Mediation effects of chronic pain ...
Source: International Journal of Mental Health and Addiction - April 30, 2024 Category: Addiction Source Type: research
Bipolar Radiofrequency Treatment of the Vaginal Canal in Conjunction with Patient Education and Pelvic Floor Rehabilitation for the Treatment of Women with Mixed Urinary Incontinence
Journal of Gynecologic Surgery, Ahead of Print. (Source: Journal of Gynecologic Surgery)
Source: Journal of Gynecologic Surgery - April 30, 2024 Category: OBGYN Authors: Rodger Rothenberger Lanna Cheuck Tracy Blusewicz Yanilis Diaz Mickey Karram Source Type: research
31. The Effect of Family History and Polygenic Risk Scores for Psychiatric Disorders on Lithium Response
Bipolar disorder (BD) is a heritable mental illness with complex genetic architecture. Polygenic risk scores (PRS) can complement family history (FH) in predicting treatment response. We aimed to investigate the association of FH and PRS for psychiatric disorders with lithium response in BD. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Mete Ercis, Brandon J. Coombes, Marin Veldic, Katherine M. Moore, Hannah K. Betcher, Francisco Romo-Nava, Aysegul Ozerdem, David J. Bond, Alfredo Cuellar- Barboza, Miguel Prieto, Susan L. McElroy, Joanna M. Biernacka, Mark A. Frye, Balwinder Singh Source Type: research
8. The Relationship Between Treatment, Symptom Severity, and Brain Connectivity in Bipolar Disorder: An International Study Across 16 Enigma-Bipolar Sites
The treatment of bipolar disorder (BD) often involves administering multiple psychotropic medications, yet little research has examined how these medications, especially when used together, affect the brain's white matter in BD. We investigate how polypharmacy and the severity of symptoms are associated with white matter connectivity in BD, in the largest neuroimaging study of its kind. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Leila Nabulsi, Melody J.Y. Kang, Neda Jahanshad, Benno Haarman, Colm McDonald, Dan Stein, David Glahn, Edith Pomarol-Clotet, Eduard Vieta, Josselin Houenou, Pauline Favre, Mircea Polosan, Paolo Brambilla, Marcella Bellani, Philip B. Mitchell, Udo Dannlows Source Type: research
7. Continuous Theta Burst Stimulation of Ventrolateral Prefrontal Cortex and Associated Reductions in Hypomanic Symptoms
Bipolar disorder is characterized by hypo/manic episodes, resulting in interfering impulsivity, reward sensitivity, and/or sensation-seeking. Elevated left ventrolateral prefrontal (vlPFC) activity during reward-expectancy shows associations with hypo/mania risk. We aimed to test whether one of three continuous theta-burst stimulation (cTBS) conditions would inhibit vlPFC and lead to hypomanic symptom reduction measured by the activation subscale of the internal state scale (ACT-ISS). (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Merage Ghane, Simona Graur, Ahmad Mayeli, Michele Bertocci, Henry Chase, Tyler Conrad, Alexander Skeba, Hope Reveche, Rachel Kaskie, Sabine Janssen, Lisa Bonar, Richelle S. Stiffler, Genna Bebko, Fabio Ferrarelli, Mary Phillips Source Type: research
DNA Methylation Biosignature of Suicide Death in the Brains of Individuals With Bipolar Disorder
Suicide death rates are elevated in individuals with bipolar disorder (BD), with past work implicating epigenetic contributions. We aimed to identify brain genome-wide DNA methylation (DNAm) changes associated with suicide death in BD. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Salahudeen Mirza, Alexandre Rubinstein, Christopher Busby, Rohit Jha, Alexandra Del Favero-Campbell, Camila Nayane de Carvalho Lima, Apurva Kumar, Mohammad Farhan, Esther Soyebo, Consuelo Walss-Bass, Jair Soares, Gabriel R. Fries Source Type: research
