DNA Methylation Biosignature of Suicide Death in the Brains of Individuals With Bipolar Disorder

Suicide death rates are elevated in individuals with bipolar disorder (BD), with past work implicating epigenetic contributions. We aimed to identify brain genome-wide DNA methylation (DNAm) changes associated with suicide death in BD.

Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Salahudeen Mirza, Alexandre Rubinstein, Christopher Busby, Rohit Jha, Alexandra Del Favero-Campbell, Camila Nayane de Carvalho Lima, Apurva Kumar, Mohammad Farhan, Esther Soyebo, Consuelo Walss-Bass, Jair Soares, Gabriel R. Fries Source Type: research