When neurons are out of shape, antidepressants may not work
(Salk Institute) Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed medication for major depressive disorder (MDD), yet scientists still do not understand why the treatment does not work in nearly thirty percent of patients with MDD. Now, Salk Institute researchers have discovered differences in growth patterns of neurons of SSRI-resistant patients. The work has implications for depression as well as other psychiatric conditions such as bipolar disorder and schizophrenia that likely also involve abnormalities of the serotonin system in the brain. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 22, 2019 Category: International Medicine & Public Health Source Type: news

Challenges in research on suicide prevention-reply - Sisti DA, Joffe S.
In Reply We are gratified to know that the FDA is developing guidance that supports inclusion of individuals with suicidal ideation or behavior associated with serious mental illnesses, including schizophrenia and bipolar disorder, in clinical trials. W... (Source: SafetyLit)
Source: SafetyLit - March 18, 2019 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news

Biotronik wins FDA nod for Acticor, Rivacor high-voltage tachycardia devices
Biotronik said yesterday it won FDA approval for its Acticor and Rivacor high-voltage cardiac rhythm management devices intended for treating patients with cardiac arrhythmias. The clearance covers the Berlin, Germany based company’s Rivacor VR-T, Rivacor DR-T, Rivacor HF-T QP, Acticor DX, Acticor CRT-DX Bipolar and Acticor CRT-DX devices. “When determining the best treatment plan for each patient, we assess individual needs and select a device system that provides optimal therapy programming with critical diagnostic features. We are often forced to choose between important features, which could compromise opti...
Source: Mass Device - March 15, 2019 Category: Medical Devices Authors: Fink Densford Tags: Cardiac Assist Devices Cardiac Implants Cardiovascular Featured Food & Drug Administration (FDA) Regulatory/Compliance Biotronik Source Type: news

Mood Stabilizers and Stroke Risk: New Data Mood Stabilizers and Stroke Risk: New Data
Dr Peter Yellowlees talks about mood stabilizers and risk for stroke in bipolar disorder.Medscape Psychiatry (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 14, 2019 Category: Consumer Health News Tags: Psychiatry Commentary Source Type: news

Prevalence and correlates of alcohol use disorders among bipolar patients at Amanuel Mental Specialized Hospital, Addis Ababa (Ethiopia): a cross-sectional institution based study - Tensae DW, Solomon H, Boru B, Getinet W.
This study aimed to assess the prevalence of AUDs among individuals with bipolar disorder i... (Source: SafetyLit)
Source: SafetyLit - March 14, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Infection in Pregnancy Elevates Risk of Child's Autism, Depression (CME/CE)
(MedPage Today) -- Similar association not observed for bipolar disorder or psychosis, including schizophrenia (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - March 12, 2019 Category: Psychiatry Source Type: news

Perceived childhood adversities: impact of childhood trauma to estimated intellectual functioning of individuals with bipolar disorder - Martins DS, Hasse-Sousa M, Petry-Perin C, Arrial-Cordeiro RT, Rabelo-da-Ponte FD, Lima FM, Rosa AR, B ücker J, Gama CS, Czepielewski LS.
Maltreatments in childhood may have implications for neurodevelopment that could remain throughout life. Childhood trauma seems to be associated with the onset of bipolar disorder (BD), and its occurrence might accentuate the overall disease impairments re... (Source: SafetyLit)
Source: SafetyLit - March 11, 2019 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Book Review: Mental Illness Is an Asshole: And Other Observations
“In a world where friends are assholes, parents are assholes, even adorable, little three-year-olds are assholes, there is no reason that psychological disorders get a pass,” writes Gabe Howard. Howard, who hosts The Psych Central Show podcast and writes for Psych Central on the topics of bipolar and mental illness, is known for his fun, entertaining and eminently useful observations about mental illness. He writes, “Bipolar, clinical depression, schizophrenia and the like have no respect for the people whose lives they impact.” In his new book, Mental Illness Is an Asshole – And Other Observa...
Source: Psych Central - March 7, 2019 Category: Psychiatry Authors: Claire Nana Tags: Anxiety Bipolar Book Reviews Depression Disorders General Habits Happiness Healthy Living Memory and Perception Motivation and Inspiration Panic Disorder Personal Stories Psychology Schizophrenia Self-Esteem Self-Help Sti Source Type: news

Infection in Pregnancy Ups Child's Autism, Depression Risk
(MedPage Today) -- Same association not observed for bipolar disorder, psychosis (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - March 6, 2019 Category: Psychiatry Source Type: news

Single gene linked to host of abnormalities during neurodevelopment
Mutations of the TRIO gene cause some of the same structural and behavioral abnormalities found with autism, schizophrenia, bipolar disorder, and epilepsy. (Source: Yale Science and Health News)
Source: Yale Science and Health News - March 5, 2019 Category: Universities & Medical Training Source Type: news

Bipolar Disorder, Schizophrenia Tied to Higher Dementia Risk Bipolar Disorder, Schizophrenia Tied to Higher Dementia Risk
Patients with bipolar disorder or schizophrenia are at a higher dementia risk than individuals without these conditions, an analysis of more than 3 million veterans suggests.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - March 5, 2019 Category: Psychiatry Tags: Psychiatry News Source Type: news

Medical News Today: How does Zoloft affect bipolar disorder?
Zoloft is a drug doctors sometimes use for the treatment of bipolar disorder, alongside others. Some side effects include nausea, diarrhea, and indigestion. Learn more about Zoloft and bipolar here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 5, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

Do Men and Women Experience Bipolar Disorder Differently?
Bipolar disorder affects men and women in equal numbers, and the symptoms are essentially identical. But some key differences do exist—differences that might be due to biological factors, and social ones, too. For starters, research has consistently shown that women have higher rates of bipolar II disorder, “which typically presents as a chronic depressive disorder with periods of hypomania,” according to Candida Fink, MD, a board-certified child, adolescent and adult psychiatrist with a private practice in Westchester, N.Y. There’s a misconception that bipolar II disorder is less severe than bipola...
Source: Psych Central - March 2, 2019 Category: Psychiatry Authors: Margarita Tartakovsky, M.S. Tags: Bipolar Disorders Gender General Men's Issues Women's Issues Bipolar Disorder bipolar disorder and pregnancy bipolar I Bipolar Ii Gender Differences men and bipolar disorder menopause and bipolar disorder menstruation and bipolar Source Type: news

Medical News Today: What are mania and hypomania?
Mania and hypomania are periods when a person feels unusually elated or energized. They are often symptoms of different types of bipolar disorder. In this article, we discuss the similarities and differences between mania and hypomania. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 2, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

Medical News Today: What counts as bipolar disorder?
To receive a bipolar disorder diagnosis, a person must have a manic episode, a depressive episode, or both. Specific types have specific diagnostic criteria. Learn more about bipolar diagnosis here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 1, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

Medical News Today: What to know about bipolar disorder and sex
Many people with bipolar disorder find that some symptoms can lead to risky sexual behavior and difficulties in relationships. Here, learn about management strategies and more. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 1, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

Medical News Today: What are the treatments for bipolar depression?
People with bipolar disorder can experience episodes of depression. They can manage these symptoms with medication, therapy, and other treatments. Learn more here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 1, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

A Pill, That ’s a Device, That Delivers a Drug!
Rani Therapeutics just achieved one of its most significant milestones since it was spun out of InCube Lab in 2012. The San Jose, CA-based company just finished conducting the first human study of its “robotic capsule” set to replace injections. Previously the device, which administers a pharmaceutical through a digestible pill, had been tested in more than 100 animal models. The human study was conducted at a Clinical Research Organization (CRO) in Texas under the Investigational Review Board (IRB) approval. There were two sub-groups, one cohort was fed and another fasted. Each subject ...
Source: MDDI - February 28, 2019 Category: Medical Devices Authors: Omar Ford Tags: Implants Source Type: news

Medical News Today: How to tell if it's bipolar disorder or ADHD
Bipolar disorder and ADHD share some symptoms, but their treatments are different. In this article, we discuss diagnosis and how to tell the two conditions apart. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 28, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

Anti-depressants cause mania in 25% of bipolar patients, study says
Drugs designed to calm mental health symptoms could be making them worse, a study says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - February 28, 2019 Category: Consumer Health News Source Type: news

Gillian Wright health latest: Cause of Eastenders star's 'unbelievable' stomach pains
GILLIAN WRIGHT portrays the role of Jean Slater on Eastenders, a bipolar disorder sufferer. Off-screen the soap opera star has had her own health battles - an ordeal where she experienced “unbelievable” stomach pains. (Source: Daily Express - Health)
Source: Daily Express - Health - February 28, 2019 Category: Consumer Health News Source Type: news

Medical News Today: What are the main symptoms of mania?
The symptoms of mania in bipolar disorder include high energy levels, euphoria, and elevated self-esteem. Learn more about bipolar mania symptoms here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 28, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

From stripping at parties to suicidal thoughts — Juliet Bravo star’s bipolar struggle
The actress, who lives in Hampshire, struggled for years. ‘I would barely want to get out of bed,’ she says. ‘The courage to make a decision, even what to wear, was too much.' (Source: the Mail online | Health)
Source: the Mail online | Health - February 25, 2019 Category: Consumer Health News Source Type: news

Psychosis May Accelerate Brain Aging Psychosis May Accelerate Brain Aging
Accelerated aging of cognitive networks after psychosis onset may offer the potential for early intervention in patients with schizophrenia or bipolar disorder, new research suggests.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 21, 2019 Category: Consumer Health News Tags: Psychiatry News Source Type: news

LivaNova touts CMS trial clearance for vagus nerve depression treatment system
LivaNova (NSDQ:LIVN) said on Wednesday that the U.S. Centers for Medicare & Medicaid Services finalized a National Coverage Decision for LivaNova’s Vagus Nerve Stimulation Therapy for treating treatment-resistant depression. The London-based company said that the modified NCD will enable Medicare coverage for VNS therapy through the Coverage with Evidence Development framework when offered through a CMS-approved, double-blind, randomized, placebo-controlled trial with a follow-up of at least 1 year. “As part of our commitment to improving the lives of patients around the world, LivaNova requested that ...
Source: Mass Device - February 21, 2019 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Neurological LivaNova Source Type: news

Medical News Today: Things to remember when a parent has bipolar disorder
Having a parent with bipolar disorder can pose challenges, such as recognizing when they are experiencing a manic or depressive episode. Learn more about dealing with a parent with bipolar disorder here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 20, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

How Common is Bipolar Disorder?
Discussion Bipolar disorder (BD) is a chronic, recurrent, affective disorder with fluctuations in energy and mood. “Bipolar disorder, previously known as manic depressive illness, is a severe chronic mood disorder characterized by episodes [note not just one instance] of mania, hypomania, and alternating or intertwining episodes of depression.” Affective disorders are classified based on their severity and extent, from unipolar to BDII to BDI. “Individuals with unipolar disorder present with depressive episodes only, and those with bipolar II or I disorder show increasingly pronounced episodes of mood ele...
Source: PediatricEducation.org - February 18, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

What Psychotic Episodes Really Look and Feel Like
When we hear someone is psychotic, we automatically think of psychopaths and cold-blooded criminals. We automatically think “Oh wow, they’re really crazy!” And we automatically think of plenty of other myths and misconceptions that only further the stigma surrounding psychosis. In other words, the reality is that we get psychosis very wrong. For starters, psychosis consists of hallucinations and/or delusions. “You can have one or both at the same time,” said Devon MacDermott, Ph.D, a psychologist who previously worked in psychiatric hospitals and outpatient centers, treating individuals experi...
Source: Psych Central - February 17, 2019 Category: Psychiatry Authors: Margarita Tartakovsky, M.S. Tags: Disorders General Schizophrenia Stigma Hallucinations Hearing Voices Psychosis Psychotic Episode serious mental illness Source Type: news

Medical News Today: How to spot bipolar symptoms in yourself
Symptoms of bipolar disorder include periods of mania and depression. Learn more about the potential signs of bipolar disorder, and when to see a doctor for a diagnosis, here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 15, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

Lithium for Bipolar Maintenance'Safe, Tolerable' in Kids Lithium for Bipolar Maintenance'Safe, Tolerable' in Kids
Lithium is safe and tolerable as maintenance therapy in children with bipolar disorder, new research suggests. However, a few concerns about the study have been flagged.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 14, 2019 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Medical News Today: Bipolar and schizophrenia symptoms
Bipolar disorder and schizophrenia have some similarities, but there are key differences. Diagnosis and treatment options vary. Here, learn more about the two conditions and when to see a doctor. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 14, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

Medical News Today: How genes influence bipolar disorder
If a person has a close relative with bipolar disorder, there is a higher chance of them developing it. Learn more about the links between genetics and bipolar disorder here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 13, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

Medical News Today: Bipolar type definitions
There are five categories of bipolar disorder. Bipolar I and II occur most frequently, while other types are less common. Learn more about the classifications of bipolar disorder here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 13, 2019 Category: Consumer Health News Tags: Psychology / Psychiatry Source Type: news

Medical News Today: Bipolar medications: Everything you need to know
There is a variety of medications that can help manage bipolar disorder, including mood-stabilizers, antidepressants, and anticonvulsants. Learn more about these and other drugs in this article. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 7, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

Medical News Today: How can bipolar disorder affect relationships?
Bipolar disorder causes alterations in mood, leading to depressive and manic or hypomanic episodes. These changes in mood can sometimes put stress on a relationship. Learn how best to navigate a relationship in which one partner has bipolar disorder. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 6, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

Medical News Today: What's the difference between borderline personality disorder and bipolar?
Although borderline personality disorder and bipolar disorder share some similar symptoms, they are different conditions. One affects a person ’s mood, while the other affects a person’s sense of self and their relationships with others. Learn more about the differences in symptoms and treatment here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 6, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

Medical News Today: How are bipolar disorder and ADHD different?
Although ADHD and bipolar disorder can share some symptoms, they are different conditions, and a person can have both of them. Learn about the differences and how doctors diagnose bipolar and ADHD. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 5, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

Medical News Today: What to know about bipolar disorder and anger
Some people with bipolar disorder experience irritability leading to anger, even though anger is not a typical symptom. Learn about why these complications occur and what to do about them here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 5, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

What Everyone Needs to Know About Bipolar Disorder
Nine years ago, Julie Kraft’s doctor uttered the words, “you have bipolar II disorder.” Immediately, images of unhinged film characters, sensationalist tabloid headlines and shocking news stories flooded her mind. All these things are now associated with me, she thought. Kraft felt embarrassed, ashamed, sad—and afraid. “I was fearful of being judged, backed away from, viewed as unsafe, unpredictable, unstable, an unreliable friend, an irresponsible mom, a moody wife, a woman of weak character, and the list goes on and on.” It’s an understandable reaction because even though bipolar...
Source: Psych Central - February 5, 2019 Category: Psychiatry Authors: Margarita Tartakovsky, M.S. Tags: Bipolar Disorders Stigma Bipolar Disorder bipolar disorder myths bipolar disorder stereotypes bipolar I Bipolar Ii Cyclothymia Hypomania Mental Health Stigma Mood Disorders Source Type: news

Medical News Today: What are the signs of bipolar in teens?
Bipolar disorder usually develops in a person ’s late teens or early adult years. It may be more difficult to diagnose bipolar in teens because of normal mood changes during puberty. In this article, we look at the signs, causes, and treatment of bipolar in teens. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 5, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

The impact of emotional temperament on medication adherence of bipolar disorder patients in intensive outpatient program - Wu D, Lu W, Sun X, Wang Y, Xue L, Huang J, Wu Z, Ye C, Wang Y, Song R, Yuan C.
OBJECTIVE To investigate the incidence of suicidal ideation and its influencing factors in patients with major depressive disorder. METHODS Beck scale for suicidal ideation (SSI) was used to evaluate the suicidal ideation of 155 patients with major... (Source: SafetyLit)
Source: SafetyLit - February 4, 2019 Category: International Medicine & Public Health Tags: Program and Other Evaluations, Effectiveness Studies Source Type: news

Risk tolerance measured by probability discounting among individuals with primary mood and psychotic disorders - Hart KL, Brown HE, Roffman JL, Perlis RH.
OBJECTIVE: Change in risk tolerance is a feature of multiple psychiatric disorders and may contribute to adverse outcomes. We used a probability discounting (PD) task to measure risk-taking behavior among individuals with bipolar disorder (BPAD), major dep... (Source: SafetyLit)
Source: SafetyLit - February 2, 2019 Category: International Medicine & Public Health Tags: Risk Perception and Communication, Warnings, Operating Instructions Source Type: news

Association between anxious distress in a major depressive episode and bipolarity - Sugawara H, Tsutsumi T, Inada K, Ishigooka J, Hashimoto M, Takebayashi M, Nishimura K.
PURPOSE: Mixed features in a major depressive episode (MDE) predict bipolar disorder (BD). The mixed features specifier included in the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) could be restrictive because it exclu... (Source: SafetyLit)
Source: SafetyLit - February 2, 2019 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Divalproex and its effect on suicide risk in bipolar disorder: a systematic review and meta-analysis of multinational observational studies - Chen TY, Kamali M, Chu CS, Yeh CB, Huang SY, Mao WC, Lin PY, Chen YW, Tseng PT, Hsu CY.
BACKGROUND: Divalproex has become the most prevalent mood stabilizer for bipolar disorder. However, little is known its effects in the prevention of suicide in patients with bipolar disorder, and recent FDA announcement indicated an increased risk of suici... (Source: SafetyLit)
Source: SafetyLit - February 2, 2019 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Gray and white matter differences in adolescents and young adults with prior suicide attempts across bipolar and major depressive disorders - Fan S, Lippard ETC, Sankar A, Wallace A, Johnston JAY, Wang F, Pittman B, Spencer L, Oquendo MA, Blumberg HP.
BACKGROUND: Findings regarding brain circuitry abnormalities in suicide attempters (SAs) converge across bipolar disorder (BD) and major depressive disorder (MDD), the most common disorders observed in suicides. These abnormalities appear to be present dur... (Source: SafetyLit)
Source: SafetyLit - February 2, 2019 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Medical News Today: Is there a cure for bipolar disorder?
Bipolar disorder is a long-term mental health condition. Although there is currently no cure, there are many treatments available that can reduce symptoms. Learn more here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 1, 2019 Category: Consumer Health News Tags: Bipolar Source Type: news

Physician's License in Limbo After Advising Pot for Boy, 4 Physician's License in Limbo After Advising Pot for Boy, 4
California's medical board ordered it revoked, saying the way the physician diagnosed the boy with ADHD and bipolar disorder was improper. But a court has granted a temporary stay, pending a hearing.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 1, 2019 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Use of a dual mobility cup to prevent hip early arthroplasty dislocation in patients at high falls risk - Nonne D, Sanna F, Bardelli A, Milano P, Rivera F.
INTRODUCTION: Hip fracture is a common serious injury that occurs mainly in elderly. Dual-mobility hip arthroplasty or bipolar emiarthroplasty for its treatment remains a controversial decision. Co-morbidities and risk of fall represent additional aspects ... (Source: SafetyLit)
Source: SafetyLit - January 31, 2019 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

UCLA-led team uncovers critical new clues about what goes awry in brains of people with autism
This study gives a new critical clue in understanding what has gone awry in the brains of autism patients.”More than 24 million people worldwide are estimated to have autism. In developed countries, about 1.5 percent of children have been diagnosed with autism spectrum disorder as of 2017. The disorder affects communication and behavior, and is marked by problems in social communication and social interaction, and repetitive behaviors.“We need to understand how a panoply of genetic and environmental factors converges to cause autism,” Geschwind said. “RNA editing is an important piece of the autism ...
Source: UCLA Newsroom: Health Sciences - January 30, 2019 Category: Universities & Medical Training Source Type: news

Decision-making and risk in bipolar disorder: a quantitative study using fuzzy trace theory - Sicilia AC, Lukacs JN, Jones S, Perez Algorta G.
This study characterizes risk-taking behaviours in a group of people with a self-reported diagnosis of BD using fuzzy trace theory (FTT). FTT hypothesizes that risk-taking is a 'reasoned' (but sometimes faulty) action, rather than an impulsive ... (Source: SafetyLit)
Source: SafetyLit - January 29, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news