Clinical Predictors Could Guide Lithium Dosage in Bipolar Disorder
Model based on six clinical predictors explained 61.4 and 49.8 percent of variance in body clearance of lithium, respectively, in two cohorts (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - May 19, 2022 Category: Psychiatry Tags: Pharmacy, Psychiatry, Journal, Source Type: news

Clinical Predictors Could Guide Lithium Dosage in Bipolar Disorder
THURSDAY, May 19, 2022 -- A model comprising six clinical variables could be used to guide lithium dosage, according to a study published in the June issue of The Lancet Psychiatry. Vincent Millischer, M.D., from the Karolinska Institutet in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 19, 2022 Category: Pharmaceuticals Source Type: news

Directly or indirectly? The role of social support in the psychological pathways underlying suicidal ideation in people with bipolar disorder - Owen R, Jones SH, Dempsey RC, Gooding PA.
Contemporary theories of suicide, such as the Schematic Appraisals Model (SAMS), hypothesize that negative perceptions of social support are implicated in the pathways to suicidal experiences. The SAMS predicts that perceived social support influences suic... (Source: SafetyLit)
Source: SafetyLit - May 16, 2022 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Eurovision's Netherlands finalist S10 has bipolar disorder & will sing about mental health
THE NETHERLANDS' Eurovision 2022 finalist S10 has struggled with bipolar disorder and often writes her songs about mental health. (Source: Daily Express - Health)
Source: Daily Express - Health - May 14, 2022 Category: Consumer Health News Source Type: news

Neuropsychiatric Ramifications of Severe COVID-19 and Other Severe Acute Respiratory Infections, JAMA Psychiatry
In cohort study (n>8 million, England), risks of new anxiety disorder, dementia, psychotic disorder& bipolar disorder diagnoses were significantly increased in adults surviving hospitalisation for COVID-19 or other severe acute respiratory infections vs general population. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 13, 2022 Category: Consumer Health News Source Type: news

New Caplyta Doses OK'd; ECT Effective Against Suicide; Antidepressants Flop for QoL
(MedPage Today) -- The FDA gave the green light to two new dosages of lumateperone (Caplyta) -- 10.5 mg and 21 mg capsules -- for the treatment of bipolar depression and schizophrenia, Intra-Cellular Therapies announced. The agent was initially... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - April 28, 2022 Category: Psychiatry Source Type: news

Altered levels of plasma inflammatory cytokines and white matter integrity in bipolar disorder patients with suicide attempts - Jiang X, Guo Y, Jia L, Zhu Y, Sun Q, Kong L, Wu F, Tang Y.
OBJECTIVE: Bipolar disorder (BD) has a higher lifetime rate of suicide attempts (SA) than other psychiatric disorders. Furthermore, BD patients with SA (BD + S) are prone to a worse quality of life. However, the pathophysiology of BD + S is poorly understo... (Source: SafetyLit)
Source: SafetyLit - April 27, 2022 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Effectiveness of medical treatment for bipolar disorder regarding suicide, self-harm and psychiatric hospital admission: between- and within-individual study on Danish national data - Fitzgerald C, Christensen RHB, Simons J, Andersen PK, Benros ME, Nordentoft M, Erlangsen A, Hawton K.
BACKGROUND: Mood stabilisers are the main treatment for bipolar disorder. However, it is uncertain which drugs have the best outcomes. AIMS: To investigate whether rates of suicide, self-harm and psychiatric hospital admission in individuals with bipolar d... (Source: SafetyLit)
Source: SafetyLit - April 25, 2022 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news

Sodium valproate: what are dangers of epilepsy drug for unborn babies?
Drug used to treat epilepsy and bipolar disorder is being given to pregnant women despite risks, data showsMHRA to look into cases of unsafe epilepsy drug being given to pregnant womenThe anti-epilepsy drug sodium valproate can cause birth defects, but data has revealed it isstill being prescribed to pregnant women in the UK, with concerns also raised that they are not always given information about the risks. But what is the drug, and how big is the problem?Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - April 17, 2022 Category: Science Authors: Nicola Davis Science correspondent Tags: Health Epilepsy Drugs Pregnancy Science UK news Source Type: news

MHRA to look into cases of unsafe epilepsy drug being given to pregnant women
Sodium valproate, associated with birth defects, reportedly being prescribed without proper warningsSodium valproate: what are dangers of epilepsy drug for unborn babies?Regulators will investigate cases where an epilepsy drug that can cause birth defects has been prescribed without proper warnings, in light of reports thatpregnant women in the UK are continuing to be given it.Sodium valproate is a drug used to treat epilepsy, and is also used in some people with bipolar disorder or migraines. However, it has been associated with a raised risk of birth defects and developmental problems if taken by pregnant women.Continue ...
Source: Guardian Unlimited Science - April 17, 2022 Category: Science Authors: Nicola Davis Science correspondent Tags: Health Epilepsy Drugs Pregnancy Science UK news Source Type: news

Risk of suicide in patients with bipolar disorder having comorbid chronic pain disorders: insights from the Nationwide Inpatient Sample Data From 2016 to 2018 - Trivedi C, Vadukapuram R, Chaudhari G, Ashraf S, Tazin F, Mansuri Z, Jain S.
Bipolar disorders (BDs) are associated with significant risk of suicide. BD patients (age ≥18 years) admitted to the hospital were identified from the National Inpatient Sample dataset. Based on the secondary diagnosis of chronic pain disorder (CPD), pat... (Source: SafetyLit)
Source: SafetyLit - April 14, 2022 Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news

Mariah Carey: 'I lived in denial and isolation' - Singer on dealing with bipolar disorder
IN 2001, Mariah Carey starred in the film Glitter, a romantic musical. But behind the cameras, she was going through the "hardest" time of her life. In recent years, she has spoken for the first time about everything that happened. (Source: Daily Express - Health)
Source: Daily Express - Health - April 9, 2022 Category: Consumer Health News Source Type: news

FDA Okays First Sublingual Med for Agitation in Schizophrenia, BD FDA Okays First Sublingual Med for Agitation in Schizophrenia, BD
The FDA has approved dexmedetomidine (IGALMI, BioXcel Therapeutics) sublingual film for the acute treatment of agitation associated with schizophrenia or bipolar disorder in adults.FDA Approvals (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - April 8, 2022 Category: Psychiatry Tags: Psychiatry News Alert Source Type: news

FDA Approves Igalmi (dexmedetomidine) Sublingual Film for Acute Treatment of Agitation Associated with Schizophrenia or Bipolar I or II Disorder in Adults
NEW HAVEN, Conn., April 06, 2022 (GLOBE NEWSWIRE) -- BioXcel Therapeutics, Inc. (Nasdaq: BTAI), a biopharmaceutical company utilizing artificial intelligence (AI) approaches to identify and develop transformative medicines in neuroscience and... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - April 6, 2022 Category: Drugs & Pharmacology Source Type: news

Like Son, Like Father: Bipolar Through The Generations
Seven years after I was first diagnosed bipolar, my dad found out he also has the disorder. This after more than 50 years living with the incorrect diagnosis of depression. (Source: WebMD Health)
Source: WebMD Health - April 2, 2022 Category: Consumer Health News Source Type: news