A longitudinal study on the impact of mental health internship in reducing negative attitudes of medical students towards people with mental disorders
RESUMO Objetivo Avaliar o efeito do internato em sa úde mental nas atitudes dos alunos de medicina quanto ao portador de transtorno mental (PTM). Métodos Atitudes foram avaliadas por questionário antes e depois do internato, por meio dos fatores: “ aceita ção social de PTM ” (F1), “ n ão acreditar em causas sobrenaturais para doença mental ” (F2), “ pap éis sociais comuns para PTM ” (F3), “ acreditar em causas psicossociais para doen ça mental ” (F4), “ intimidade ” (F5). Diferen ças foram avali...
Source: Jornal Brasileiro de Psiquiatria - October 22, 2019 Category: Psychiatry Source Type: research

Mental disorders and suicide risk in emerging adulthood: the 1993 Pelotas birth cohort
CONCLUSIONS Our findings showed that about 20% of the youths had at least one mental disorder. However, this prevalence is underestimated since other relevant mental disorders were not assessed. Mental disorders were associated with higher suicide risk, especially the comorbidity between them. (Source: Revista de Saude Publica)
Source: Revista de Saude Publica - October 22, 2019 Category: International Medicine & Public Health Source Type: research

Prescribing Lithium During Pregnancy Requires Careful Balancing of Benefits, Risks
The risk of giving birth to a child with birth defects may be slightly higher in women with bipolar disorder who take lithium compared with those who do not take lithium, suggests ameta-analysis inAJP in Advance. However, these slight risks may be outweighed by the dangers to mother and child of relapse of illness episodes (either depressive or manic), the authors of the analysis caution.“Pregnancy should not be considered an absolute contraindication to lithium prescription, given the relatively small increase in risk for any malformation or cardiac malformations, and given that such events, fortunately, remain rare...
Source: Psychiatr News - October 21, 2019 Category: Psychiatry Tags: ajp in advance bipolar disorder cardiac birth defect congenital defect lithium meta-analysis Michele Fornaro miscarriage relapse Source Type: research

A randomized, controlled trial for transurethral treatment of bladder tumors using PlasmaButton vaporization electrode or monopolar loop electrocautery.
CONCLUSION: The results of this study demonstrated no difference between the monopolar loop and PK Button in regard to overall complications; however, there was a higher rate of bladder perforation with monopolar TURBT. PK Button vaporization for bladder tumors represents a promising alternative to traditional monopolar TURBT without compromising short term (3 month) cancer recurrence rates. PMID: 31629439 [PubMed - in process] (Source: Canadian Journal of Urology)
Source: Canadian Journal of Urology - October 21, 2019 Category: Urology & Nephrology Tags: Can J Urol Source Type: research

LEA 10. Experimental Model to Assess the Safety of Energy Sealing Devices in Saphenous Vein Graft in Bypass Surgery
Energy sealing devices achieve hemostasis of the blood vessels through sequential coagulation and transection. Although use has been widely spread in multiple surgical fields, safety for sealing collaterals of autologous grafts during bypass surgery is unknown. We compare the efficacy of the main sealing devices used, Electrothermal Bipolar Tissue Sealing System (EB; LigaSure, Valleylab Inc, Boulder, Colo) and Harmonic scalpel (HS; Ethicon, Somerville, NJ), vs conventional vessel ligation of saphenous vein collaterals for revascularization surgery. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - October 21, 2019 Category: Surgery Authors: Mois és Falcón Espínola, Irene Ramos Moreno, Rafael Martínez López, Nohelia Rojas Ferrer, Lucas Ribé Bernal, Manuel Miralles Hernández Source Type: research

< i > Cis < /i > -regulatory basis of sister cell type divergence in the vertebrate retina
Multicellular organisms evolved via repeated functional divergence of transcriptionally related sister cell types, but the mechanisms underlying sister cell type divergence are not well understood. Here, we study a canonical pair of sister cell types, retinal photoreceptors and bipolar cells, to identify the keycis-regulatory features that distinguish them. By comparing open chromatin maps and transcriptomic profiles, we found that while photoreceptor and bipolar cells have divergent transcriptomes, they share remarkably similarcis-regulatory grammars, marked by enrichment of K50 homeodomain binding sites. However, cell cl...
Source: eLife - October 21, 2019 Category: Biomedical Science Tags: Chromosomes and Gene Expression Genetics and Genomics Source Type: research

Looking Beyond Numbers: Lithium Toxicity Within Therapeutic Levels
A 65-year-old man was admitted with slurred speech of acute onset. He had a past medical history of type 2 diabetes mellitus, hypertension and bipolar disorder on metformin, amlodipine and lithium. He had difficulty pronouncing simple words and was speaking incoherently. He seemed confused and had difficulty walking. There had been no recent falls, head trauma or alcohol ingestion. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 21, 2019 Category: General Medicine Authors: Jonathan Edward Jacob, Wei Qiang Chng, Desmond B. Teo Tags: Clinical Communications to the Editor Source Type: research

Previous arthroscopic Bankart repair is an independent risk factor for an inferior outcome after Latarjet procedure
DiscussionA previous failed arthroscopic Bankart repair was a significant independent risk factor for inferior outcome. Preoperative bony pathology did not explain the worse outcome from the revision vs. primary Latarjet procedure.Level of evidenceIV, cohort observational study. (Source: Orthopaedics and Traumatology: Surgery and Research)
Source: Orthopaedics and Traumatology: Surgery and Research - October 20, 2019 Category: Orthopaedics Source Type: research

Rapid hemostasis: a novel and effective outpatient procedure using microwave ablation to control epistaxis of isolated mucosal bulge lesions
ConclusionsEndoscopic microwave ablation with patients under local anesthesia is a novel, safe, effective, rapid, well-tolerated, outpatient treatment for adults with epistaxis of isolated mucosal bulge lesions, especially those for whom general anesthesia might be risky, those with electrical implants, and those exhibiting contraindications for arterial embolization.ResumoIntroduçãoEpistaxe recorrente é uma condição clínica comum nos ambulatórios de rinologia. Sob visualização endoscópica, tanto o cautério bipolar quanto a pinça monopolar ...
Source: Brazilian Journal of Otorhinolaryngology - October 20, 2019 Category: ENT & OMF Source Type: research

Correlation between GRIK2 rs6922753, rs2227283 polymorphism and aggressive behaviors with Bipolar Mania in the Chinese Han population
ConclusionThis study suggests that the rs2227283 polymorphism of the GRIK2 gene is related to aggressive behaviors in bipolar manic patients and that the A/A genotype and A allele may increase the risk of the aggressive behavior in bipolar manic patients. (Source: Brain and Behavior)
Source: Brain and Behavior - October 20, 2019 Category: Neurology Authors: Haibo Ma, Guanglei Xun, Renyun Zhang, Xiaohua Yang, Yu Cao Tags: ORIGINAL RESEARCH Source Type: research

[Mirtazapine-Induced Mania: A Case Report].
Authors: Freitas C, Barranha R, Abreu T, Von Doellinger O Abstract Manic and hypomanic states associated with antidepressant treatments are relatively common; however, when specifically considering mirtazapine, those side effects are infrequent. The authors report a clinical case regarding a manic episode with dysphoric features in a patient with no personal or family previous psychiatric history. It began two weeks after starting treatment with mirtazapine up to 30 mg/day. This episode was treated discontinuing mirtazapine and initiating olanzapine (10 mg), with symptomatic remission. Mirtazapine has a specific ph...
Source: Acta Medica Portuguesa - October 19, 2019 Category: General Medicine Tags: Acta Med Port Source Type: research

Neural Responses to Monetary Incentives in Bipolar Disorder: Neural Responses to Incentives in Bipolar Disorder
Publication date: Available online 18 October 2019Source: NeuroImage: ClinicalAuthor(s): Sheri L. Johnson, Hershel Mehta, Terence A. Ketter, Ian H. Gotlib, Brian KnutsonAbstractAlthough behavioral sensitivity to reward predicts the onset and course of mania in bipolar disorder, the evidence for neural abnormalities in reward processing in bipolar disorder is mixed. To probe neural responsiveness to anticipated and received rewards in the context of bipolar disorder, we scanned individuals with remitted bipolar I disorder (n=24) and well-matched controls (n=24; matched for age and gender) using Functional Magnetic Resonance...
Source: NeuroImage: Clinical - October 19, 2019 Category: Radiology Source Type: research

Bacterial infections in pregnancy may make schizophrenia more likely
Children of mothers who had bacterial infections during pregnancy are more likely to develop mental health conditions like schizophrenia and bipolar disorder (Source: New Scientist - Health)
Source: New Scientist - Health - October 19, 2019 Category: Consumer Health News Source Type: research

Operating Costs of Full-endoscopic Lumbar Spine Surgery in Japan.
Authors: Manabe H, Tezuka F, Yamashita K, Sugiura K, Ishihama Y, Takata Y, Sakai T, Maeda T, Sairyo K Abstract For full-endoscopic lumbar discectomy, operating costs are also important because expensive equipment are necessary. We surveyed the operating costs of surgical equipment necessary for full-endoscopic surgery together with surgical procedure reimbursement fees. A total of 295 cases of full-endoscopic surgery via a transforaminal approach were retrospectively analyzed. We calculated the frequency of damage and the unit purchase price of devices such as endoscopes, and surgical instruments such as grasping f...
Source: Neurologia Medico-Chirurgica - October 19, 2019 Category: Neurosurgery Tags: Neurol Med Chir (Tokyo) Source Type: research

Induced cardiac progenitor cells repopulate decellularized mouse heart scaffolds and differentiate to generate cardiac tissue
This article is part of a Special Issue entitled: Cardiomyocyte biology: new pathways of differentiation and regeneration edited by Marijke Brink, Marcus C. Schaub, and Christian Zuppinger. (Source: Biochimica et Biophysica Acta (BBA) Molecular Cell Research)
Source: Biochimica et Biophysica Acta (BBA) Molecular Cell Research - October 19, 2019 Category: Molecular Biology Source Type: research

Screening of electrocatalysts for hydrogen evolution reaction using bipolar electrodes fabricated by composition gradient magnetron sputtering
Publication date: Available online 16 October 2019Source: Journal of Electroanalytical ChemistryAuthor(s): Vitalii Latyshev, Serhii Vorobiov, Oleg Shylenko, Vladimir KomanickyAbstractThis paper reports the facile fabrication of bipolar electrodes using composition gradient magnetron sputtering and subsequent activity screening of the prepared electrodes for hydrogen evolution reaction using bipolar electrochemistry. The electrocatalysts layers based on Ni–Mo, Au–Mo and Au–Ni alloys were deposited in form of compositional gradients on the bipolar electrodes. Concentration of the elements in the gradients v...
Source: Journal of Electroanalytical Chemistry - October 19, 2019 Category: Chemistry Source Type: research

Is bipolar post-partum depression overlooked?
Publication date: November 2019Source: The Lancet Psychiatry, Volume 6, Issue 11Author(s): Verinder Sharma, Christine Baczynski (Source: The Lancet Psychiatry)
Source: The Lancet Psychiatry - October 18, 2019 Category: Psychiatry Source Type: research

Lithium Treatment in a Severely Depressed Child At Risk for Bipolar Disorder.
Authors: Nogueira-Lima G, Boarati MA, Fu-I L Abstract PMID: 31617967 [PubMed - in process] (Source: The Primary Care Companion for CNS Disorders)
Source: The Primary Care Companion for CNS Disorders - October 18, 2019 Category: Primary Care Tags: Prim Care Companion CNS Disord Source Type: research

Evaluation Of Subjective Cognitive Function Using The Cognitive Complaints In Bipolar Disorder Rating Assessment (COBRA) In Japanese Adults
(Source: Neuropsychiatric Disease and Treatment)
Source: Neuropsychiatric Disease and Treatment - October 18, 2019 Category: Psychiatry Tags: Neuropsychiatric Disease and Treatment Source Type: research

Investigating the association between anxiety symptoms and mood disorder in high-risk offspring of bipolar parents: a comparison of Joint and Cox models
Anxiety is associated with mood disorders including bipolar disorder. Two statistical modelling frameworks were compared to investigate the longitudinal relationship between repeatedly measured anxiety symptom... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - October 18, 2019 Category: Psychiatry Authors: Ruoxi Dong, George Stefan, Julie Horrocks, Sarah M. Goodday and Anne Duffy Tags: Research Source Type: research

The Dynamics of Microglial Polarization Reveal the Resident Neuroinflammatory Responses After Subarachnoid Hemorrhage
In this study, we investigated the dynamics of microglial reaction in an endovascular perforated SAH model. By using the Cx3cr1GFP/GFP Ccr2RFP/RFP transgenic mice, we found that the reactive immune cells were largely from resident microglia pool rather than infiltrating macrophages. Immunostaining and real-time PCR were employed to analyze the temporal microglial polarization and the resulting inflammatory responses. Our results showed that microglia accumulated immediately after SAH with a centrifugal spreading through the Cortex Adjacent to the Perforated Site (CAPS) to the remote motor cortex. Microglia polarized dynami...
Source: Translational Stroke Research - October 18, 2019 Category: Neurology Source Type: research

Lithium Exposure During Pregnancy and the Postpartum Period: A Systematic Review and Meta-Analysis of Safety and Efficacy Outcomes.
lmi M Abstract OBJECTIVE: Uncertainty surrounds the risks of lithium use during pregnancy in women with bipolar disorder. The authors sought to provide a critical appraisal of the evidence related to the efficacy and safety of lithium treatment during the peripartum period, focusing on women with bipolar disorder and their offspring. METHODS: The authors conducted a systematic review and random-effects meta-analysis assessing case-control, cohort, and interventional studies reporting on the safety (primary outcome, any congenital anomaly) or efficacy (primary outcome, mood relapse prevention) of lithium treat...
Source: The American Journal of Psychiatry - October 18, 2019 Category: Psychiatry Authors: Fornaro M, Maritan E, Ferranti R, Zaninotto L, Miola A, Anastasia A, Murru A, Solé E, Stubbs B, Carvalho AF, Serretti A, Vieta E, Fusar-Poli P, McGuire P, Young AH, Dazzan P, Vigod SN, Correll CU, Solmi M Tags: Am J Psychiatry Source Type: research

Green chromatographic methods for simultaneous determination of quetiapine and the co-administrated paroxetine in rat plasma with application to pharmacokinetic study
Publication date: Available online 14 October 2019Source: Microchemical JournalAuthor(s): Nada S. Abdelwahab, Amal B. Ahmed, Mahmoud A. Omar, Sayed M. Derayea, Maha M. AbdelrahmanABSTRACTNewly established green TLC-densitometric and RP-HPLC methods were developed and validated for simultaneous determination of quetiapine (QUT) (an antipsychotic drug) and the co-administrated drug, paroxetine (PAR) (an antidepressant drug). Both drugs are widely prescribed for treatment of bipolar depression. The proposed TLC-densitometric method was based on separation of the studied components and the internal standard (vincamine (VINC)) ...
Source: Microchemical Journal - October 17, 2019 Category: Chemistry Source Type: research

Practical considerations for the evaluation and management of Attention Deficit Hyperactivity Disorder (ADHD) in adults.
This article aims to provide practical considerations for the management of ADHD and associated disorders in adults, in this particular French context. PMID: 31610922 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - October 17, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Triple Chronotherapy for Bipolar Depression: A Case Report].
In this report, we present a case of bipolar depression undergoing triple chronotherapy in addition to the standard treatment and discuss the importance of getting fast and sustained response in these cases. PMID: 31613981 [PubMed - in process] (Source: Turkish Journal of Psychiatry)
Source: Turkish Journal of Psychiatry - October 17, 2019 Category: Psychiatry Authors: Kahyacı Kılıç E, Çalıyurt O Tags: Turk Psikiyatri Derg Source Type: research

Pharmacologic Treatment of Psychiatric Disorders and Time With Unsuppressed HIV Viral Load in a Clinical HIV Cohort
Conclusions: PLWH with depressive and bipolar disorders, particularly when untreated, spent more time with unsuppressed VL than PLWH without a mood disorder. Treatment of mood disorders may be important for promoting sustained viral suppression. (Source: JAIDS Journal of Acquired Immune Deficiency Syndromes)
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - October 17, 2019 Category: Infectious Diseases Tags: Clinical Science Source Type: research

Pharmacological Manipulation of the Circadian Clock: A Possible Approach to the Management of Bipolar Disorder
AbstractBipolar disorder (BD) is a mood disorder with genetic and neurobiological underpinnings, characterized primarily by recurrent episodes of mania and depression, with notable disruptions in rhythmic behaviors such as sleep, energy, appetite and attention. The chronobiological links to BD are further supported by the effectiveness of various treatment modalities such as bright light, circadian phase advance, and mood-stabilizing drugs such as lithium that have effects on the circadian clock. Over the past 30  years, the neurobiology of the circadian clock has been exquisitely described and there now exists a deta...
Source: CNS Drugs - October 17, 2019 Category: Neurology Source Type: research

Extirpation of a Ruptured Anterior Spinal Artery Aneurysm Accompanied by Dural Arteriovenous Fistula at the Craniovertebral Junction via a Posterolateral Approach: The Management of Extradural Venous Congestion
Conclusion Controlling extradural venous congestion is essential to obtain a clear operative field in cases of arteriovenous shunt disease at the craniovertebral junction.The link to the video can be found at: https://youtu.be/fCT69WtAQbo. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: Journal of Neurological Surgery Part B: Skull Base)
Source: Journal of Neurological Surgery Part B: Skull Base - October 17, 2019 Category: Neurosurgery Authors: Hanakita, Shunya Oya, Soichi Tsuchiya, Tsukasa Shojima, Masaaki Matsui, Toru Tags: Skull Base: Operative Videos Source Type: research

Shared Genetics of Asthma and Mental Health Disorders: A Large-Scale Genome-Wide Cross-Trait Analysis.
Abstract Epidemiological studies demonstrate an association between asthma and mental health disorders, although little is known about the shared genetics and causality of this association. Thus, we aim to investigate shared genetic and the causal link between asthma and mental health disorders.We conducted a large-scale genome-wide cross-trait association study to investigate genetic overlap between asthma from UK Biobank and 8 mental health disorders from Psychiatric Genomics Consortium, including: attention deficit hyperactivity disorder (ADHD), anxiety disorder (ANX), autism spectrum disorder, bipolar disorder...
Source: Respiratory Care - October 17, 2019 Category: Respiratory Medicine Authors: Zhu Z, Zhu X, Liu CL, Shi H, Shen S, Yang Y, Hasegawa K, Camargo CA, Liang L Tags: Eur Respir J Source Type: research

Docosahexaenoic acid,22:6n-3: its roles in the structure and function of the brain.
Abstract Docosahexaenoic acid,22:6n-3 (DHA) and its metabolites are vital for the structure and functional brain development of the fetus and infants, and also for maintenance of healthy brain function of adults. DHA is thought to be an essential nutrient required throughout the life cycle for the maintenance of overall brain health. The mode of actions of DHA and its derivatives at both cellular and molecular levels in the brain are emerging. DHA is the major prevalent fatty acid in the brain membrane. The brain maintains its fatty acid levels mainly via the uptake of plasma free fatty acids. Therefore, circulati...
Source: International Journal of Developmental Neuroscience - October 17, 2019 Category: Neuroscience Authors: Mallick R, Basak S, Duttaroy AK Tags: Int J Dev Neurosci Source Type: research

Integrative Transcriptomics Reveals Sexually Dimorphic Control of the Cholinergic/Neurokine Interface in Schizophrenia and Bipolar Disorder
Publication date: 15 October 2019Source: Cell Reports, Volume 29, Issue 3Author(s): Sebastian Lobentanzer, Geula Hanin, Jochen Klein, Hermona SoreqSummaryRNA sequencing analyses are often limited to identifying lowest p value transcripts, which does not address polygenic phenomena. To overcome this limitation, we developed an integrative approach that combines large-scale transcriptomic meta-analysis of patient brain tissues with single-cell sequencing data of CNS neurons, short RNA sequencing of human male- and female-originating cell lines, and connectomics of transcription factor and microRNA interactions with perturbed...
Source: Cell Reports - October 16, 2019 Category: Cytology Source Type: research

Immune response to stress induction as a predictor of cognitive-behavioral therapy outcomes in adolescent mood disorders: A pilot study
This study offers preliminary evidence that immune responsivity to stress induction could serve as a mechanism of treatment for mood disorders in youth, indicating a potential marker for more personalized model of healthcare. (Source: Journal of Psychiatric Research)
Source: Journal of Psychiatric Research - October 16, 2019 Category: Psychiatry Source Type: research

Mental disorders, suicide attempt and suicide: differences in the association in refugees compared with Swedish-born individuals.
CONCLUSIONS: For most mental disorders, refugees were less likely to be admitted to hospital for suicide attempt or die by suicide compared with Swedish-born individuals. Further research on risk and protective factors for suicide attempt and suicide among refugees with mental disorders is warranted. DECLARATION OF INTEREST: None. PMID: 31608856 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 16, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Single-Step Exfoliation of Black Phosphorus and Deposition of Phosphorene via Bipolar Electrochemistry for Capacitive Energy Storage Application
J. Mater. Chem. A, 2019, Accepted Manuscript DOI: 10.1039/C9TA09641H, PaperAmin Rabiei Baboukani, Iman Khakpour, Vadym Drozd, Anis Allagui, Chunlei Wang Black phosphorus (BP) is a two-dimensional material that has gained attention for various applications due to its exceptional physical and chemical properties such as tunable bandgap and high charge carrier... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - J. Mater. Chem. latest articles)
Source: RSC - J. Mater. Chem. latest articles - October 16, 2019 Category: Chemistry Authors: Amin Rabiei Baboukani Source Type: research

Treatment emergent affective switch with intermittent theta burst stimulation over right temporo-parietal junction: a case report
We report the case of a 42-year-old female, diagnosed with major depressive disorder (recurrent) and psychogenic non epileptic seizures (PNES), who showed TEAS with intermittent theta burst stimulation (iTBS). She presented with an episode of low mood, vague pain symptoms such as headache, reduced interest, easy fatigability, disturbed sleep and impaired activities of daily living for one month. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - October 16, 2019 Category: Neurology Authors: Shobit Garg, Rashi Agarwal, Sai Krishna Tikka, Sumit Khattri Source Type: research

Drugs used in the treatment of bipolar disorder and their effects on cholesterol biosynthesis – A possible therapeutic mechanism
. (Source: World Journal of Biological Psychiatry)
Source: World Journal of Biological Psychiatry - October 16, 2019 Category: Psychiatry Authors: Srisaiyini Kidnapillai Chiara C. Bortolasci Bruna Panizzutti Briana Spolding Timothy Connor Kamila Bonifacio Andrew Sanigorski Olivia M. Dean Tamsyn Crowley St éphane Jamain Laura Gray Marion Leboyer Michael Berk Ken Walder Source Type: research

Deciphering Retinal Diseases through the Generation of Three Dimensional Stem Cell ‐derived Organoids
Schematic overview of current hiPSCs disease 3D retinal modeling. Somatic cells from patients are reprogrammed toward human induced pluripotent stem cells (hiPSCs). Derived 3D retinal organoids from hiPSCs serve as a model for further investigation of disease mechanisms, drug, and toxicological screening as well as for future developments of new therapies in patients. The application of gene ‐editing technology in patient's hiPSCs could create the gene‐corrected 3D organoids as a cell source for transplantation therapy of hereditary retinal dystrophies. Abbreviations: PRs, photoreceptors; GCs, ganglion cells; HCs, hori...
Source: Stem Cells - October 16, 2019 Category: Stem Cells Authors: Ana Artero Castro, Francisco Javier Rodr íguez Jimenez, Pavla Jendelova, Slaven Erceg Tags: Embryonic Stem Cells/Induced Pluripotent Stem Cells Source Type: research

Prevalence of Mental Disorders and Suicidality in Canadian Provinces.
CONCLUSIONS: Significant interprovincial differences were found in the past-year prevalence of mental disorders and suicidality in Canada. More research is necessary to explore these differences and how they impact the need for mental health services. PMID: 31619055 [PubMed - as supplied by publisher] (Source: Canadian Journal of Psychiatry)
Source: Canadian Journal of Psychiatry - October 16, 2019 Category: Psychiatry Authors: Palay J, Taillieu TL, Afifi TO, Turner S, Bolton JM, Enns MW, Smith M, Lesage A, Bakal JA, Rush B, Adair CE, Vigod SN, Clelland S, Rittenbach K, Kurdyak P, Sareen J Tags: Can J Psychiatry Source Type: research

Deciphering Retinal Diseases through the Generation of Three Dimensional Stem Cell ‐derived Organoids
Schematic overview of current hiPSCs disease 3D retinal modeling. Somatic cells from patients are reprogrammed toward human induced pluripotent stem cells (hiPSCs). Derived 3D retinal organoids from hiPSCs serve as a model for further investigation of disease mechanisms, drug, and toxicological screening as well as for future developments of new therapies in patients. The application of gene ‐editing technology in patient's hiPSCs could create the gene‐corrected 3D organoids as a cell source for transplantation therapy of hereditary retinal dystrophies. Abbreviations: PRs, photoreceptors; GCs, ganglion cells; HCs, hori...
Source: Stem Cells - October 16, 2019 Category: Stem Cells Authors: Ana Artero Castro, Francisco Javier Rodr íguez Jimenez, Pavla Jendelova, Slaven Erceg Tags: Embryonic Stem Cells/Induced Pluripotent Stem Cells Source Type: research

2662 Accurate Dissection in Robotic Surgery Using the Double Bipolar Method-With Pinpoint Accuracy
ConclusionThe pinpoint accuracy of the bipolar method allowed for safe and complete dissection. (Source: Journal of Minimally Invasive Gynecology)
Source: Journal of Minimally Invasive Gynecology - October 15, 2019 Category: OBGYN Source Type: research

2059 TSS – Time Sparing Sacrocolpopexy: How to Reduce the Operative Time of Laparoscopic Sacrocolpopexy
ConclusionThese modifications to the technique will help shorten operation times and reduce complications of LSC. (Source: Journal of Minimally Invasive Gynecology)
Source: Journal of Minimally Invasive Gynecology - October 15, 2019 Category: OBGYN Source Type: research

2021 Hysteroscopic Polypectomy with Stone Retrieval Basket
ConclusionThe utilization of a stone retrieval basket is a novel and effective method for retrieving a wide based endometrial polyp following incomplete resection with hysteroscopic scissors. (Source: Journal of Minimally Invasive Gynecology)
Source: Journal of Minimally Invasive Gynecology - October 15, 2019 Category: OBGYN Source Type: research

Bipolar resistive switching, synaptic plasticity and non-volatile memory effects in the solution-processed zinc oxide thin film
Publication date: February 2020Source: Materials Science in Semiconductor Processing, Volume 106Author(s): V.L. Patil, Aditya A. Patil, S.V. Patil, N.A. Khairnar, N.L. Tarwal, S.A. Vanalakar, R.N. Bulakhe, Insik In, P.S. Patil, T.D. DongaleAbstractThe memristive devices are getting a lot of interest in recent years due to its applications in the field of resistive memory and brain-inspired computing. In the present work, we have developed a ZnO memristive device using the reflux method. We have demonstrated non-volatile memory properties and mimicked the basic synaptic properties of using Al/ZnO/FTO thin film device. The s...
Source: Materials Science in Semiconductor Processing - October 15, 2019 Category: Materials Science Source Type: research

2021 Hysteroscopic Polypectomy with Stone Retrieval Basket
To present an alternative approach to hysteroscopic endometrial polypectomy. Currently most hysteroscopic polypectomy procedures are performed using a single use instruments such as a bipolar resectoscope or one of the several commercially available hysteroscopic morcellation devices. This surgical procedure allows the completion of a hysteroscopic polypectomy without incurring the costs associated with these single use instruments. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 15, 2019 Category: OBGYN Authors: PR Movilla, PL Rosenblatt Tags: Virtual Poster Session 3: Hysteroscopy (10:40 AM – 10:50 AM) 10:40 AM: STATION R Source Type: research

Benign Endometrial Polyp Recurrence after Office Hysteroscopic Polypectomy According to Surgical Procedure
To compare the recurrence of benign endometrial polyps after hysteroscopic polypectomy performed with bipolar electrode (BE) or a small diameter hysteroscopic tissue removal system (HTRs). (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 15, 2019 Category: OBGYN Authors: OR Ceci, M Franchini, R Cannone, S Cardinale, S Bettocchi, E Cicinelli Tags: Open Communications 3: Hysteroscopy (11:00 AM — 12:45 PM) 11:49 AM Source Type: research

2662 Accurate Dissection in Robotic Surgery Using the Double Bipolar Method-With Pinpoint Accuracy
To demonstrate the accuracy of dissection of the double bipolar method in robotic surgery.We will show operative techniques used in real surgical settings for procedures such as modified radical hysterectomy and retroperitoneal lymphadenectomy for clinical stage I endometrial cancer. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 15, 2019 Category: OBGYN Authors: M Andou Tags: Virtual Poster Session 4: Oncology (1:30 PM — 1:40 PM) 1:30 PM STATION C Source Type: research

Robotic-Assisted Laparoscopic Excision of C-Section Scar Ectopic Pregnancy with Bipolar Coagulation of Uterine Vessels
To describe a technique of robotic-assisted laparoscopic excision of c-section scar ectopic pregnancy (CSP) with bipolar coagulation of uterine vessels. (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - October 15, 2019 Category: OBGYN Authors: CC De Amorim Paiva, I Alagkiozidis, MA Son, A Elfeky Tags: Open Communications 16:  Robotics (11:00 AM – 12:45 PM) 11:14 AM Source Type: research

Cost –utility analysis of blister packaging all outpatient medications for veterans with bipolar disorder, major affective disorder, post‐traumatic stress disorder or schizophrenia
ConclusionsIn this group of veterans with serious mental illnesses, our results suggest that blister packaging all outpatient prescription medications was budget ‐neutral. Blister packaging may be a cost‐effective barrier to intentional overdose with prescribed medications. (Source: Journal of Pharmaceutical Health Services Research)
Source: Journal of Pharmaceutical Health Services Research - October 15, 2019 Category: Drugs & Pharmacology Authors: Jill E Lavigne, Kristin Falbo, Peter M Gutierrez Tags: Research Paper Source Type: research

Risk of Developing Parkinson Disease in Bipolar Disorder
This systematic review and meta-analysis assesses the association of bipolar disorder with a later diagnosis of idiopathic Parkinson disease. (Source: JAMA Neurology)
Source: JAMA Neurology - October 14, 2019 Category: Neurology Source Type: research

Inflammation, brain structure and cognition interrelations among individuals with differential risks for bipolar disorder
In this study, we investigated the interrelations among interleukin (IL)-6 cytokine level, grey matter (GM) volume of the anterior cingulated cortex (ACC), and attention function among offspring of parents diagnosed with BD. The offspring were categorized as being either asymptomatic or symptomatic based on whether they manifested pre-defined sub-threshold mood symptoms. We found that the symptomatic offspring showed significantly higher serum levels of IL-6 than the asymptomatic offspring (F (1, 59) = 67.65, p0.05). Mediation analyses revealed that the GM volume of the rostral ACC significantly mediated the negative assoc...
Source: Brain, Behavior, and Immunity - October 14, 2019 Category: Neurology Source Type: research