Po-01-100 multipolar electrograms: a new electrogram configuration that improves the accuracy of electroanatomical mapping: basics, evidence, and tips on how to use it in practice
Accurate measurements of intracardiac electrograms (EGMs) remains a clinical challenge due to suboptimal attenuation of far-field potentials. Multielectrode mapping catheters provide an opportunity to construct "Multipolar" instead of "Bipolar" EGMs to more effectively attenuate far-field activities recorded from a larger and a multi-vectorial space. (Source: Heart Rhythm)
Source: Heart Rhythm - May 1, 2024 Category: Cardiology Authors: Elad Anter, Ofir Brem, Lior Greenbaum, Zachary P. Bubar, Jonathan Yarnitsky, Hagai D. Yavin, Arwa Younis, Michael Barkagan Source Type: research

Po-01-144 epicardial ventricular tachycardia substrate revealed by coronary vein mapping: comparison with epicardial surface mapping
Ventricular tachycardia (VT) may originate from epicardial substrates (ES). Bipolar voltage mapping via pericardial puncture (PP) is the gold standard to discern ES. The role of epicardial fat in masking ES is unknown. Venous mapping is unaffected by epicardial fat. (Source: Heart Rhythm)
Source: Heart Rhythm - May 1, 2024 Category: Cardiology Authors: Armen A. Kocharian, Paul A. Schurmann, Miguel Valderrabano Source Type: research

Po-01-129 tripolar ablation – a new ablation approach combining bipolar ablation with an additional dispersive electrode: first insights in clinical use and ex-vivo-validation
Ablation of ventricular arrhythmias originating from intramural substrate is challenging. Bipolar ablation, capable of creating transmural and rectangular lesions, faces limitations in scenarios with high impedance between catheters. (Source: Heart Rhythm)
Source: Heart Rhythm - May 1, 2024 Category: Cardiology Authors: Emily Schultz, Fabian Bahlke, Nico Erhard, Florian Englert, Hannah Krafft, Miruna A. Popa, Jan Syvaeri, Patricia Bicprendi, Madeleine Tydecks, Alex Tunsch Martinez, Sarah Lengauer, Marta Telishevska, Edison Abdiu, Gabriele Hessling, Isabel Deisenhofer Source Type: research

Po-01-117 omnipolar and vector mapping in premature ventricular contractions ablation: a comparison with bipolar mapping
Omnipolar Mapping overcomes the dependency of EGM characteristics to wavefront orientation, reconstructing the highest peak-to-peak voltage attainable within the electric field and the real wavefront direction, displayed as a local activation vector (Source: Heart Rhythm)
Source: Heart Rhythm - May 1, 2024 Category: Cardiology Authors: Pasquale Valerio Falzone, Sara Vazquez-Calvo, Jean-Baptiste Guichard, Andreu Porta-Sanchez, Ivo Roca-Luque Source Type: research

Mp-483499-002 unipolar voltage threshold of 5.47 mv in the left atrium predicts regions of difficult radiofrequency catheter ablation to achieve transmural isolation in af patients.
In contrast to bipolar (Bip) signals, unipolar (Unip) sensing allows to record electrical activity from the endo to the epicardium. A research of our lab showed that Unip voltage values in LA are highly variable and show a normal distribution, high Unip segments of the PW and PVs reproduce myofiber arrangement and wall thickness variation. (Source: Heart Rhythm)
Source: Heart Rhythm - May 1, 2024 Category: Cardiology Authors: Luis Saenz, William F. Bautista Vargas, Carlos A. Tapias, Boris Hernandez, Juan Cabrera, Valentina Stozitzky, Christian Adams Source Type: research

Mp-470546-008 epicardial unipolar and bipolar mapping in brugada syndrome: characteristics and comparison with overt cardiomyopathy
Epicardial unipolar mapping has not been well investigated in Brugada syndrome (BrS). (Source: Heart Rhythm)
Source: Heart Rhythm - May 1, 2024 Category: Cardiology Authors: Satoshi Nagase, Naoya Kataoka, Hiroshi Morita, Tsukasa Kamakura, Akira Ueoka, Toshihiro Nakamura, Satoshi Oka, Yuichiro Miyazaki, Akinori Wakamiya, Kenzaburo Nakajima, Nobuhiko Ueda, Mitsuru Wada, kohei ishibashi, Yuko Inoue, Koji Miyamoto, Takeshi Aiba, Source Type: research

Pe-482890-002 midterm multicenter results of a novel pediatric pacemaker in neonates and infants
Although the need for pacemakers in neonates and children is rare, they are vital in certain clinical scenarios. Standard pacemaker generators are comparatively large to a small neonate, potentially leading to significant complications. A novel specially modified pediatric-sized implantable pulse generator (IPG) was developed containing a Medtronic Micra VRTM subassembly incorporated into a polymer header allowing connection to a standard bipolar epicardial lead. (Source: Heart Rhythm)
Source: Heart Rhythm - May 1, 2024 Category: Cardiology Authors: Lindsey Haack, Robert D. Whitehill, Dustin Nash, Soham Dasgupta, Christopher L. Johnsrude, Stephanie F. Chandler, Marc D. LeGras, Bradley C. Clark, Erick E. Jimenez, Heather M. Giacone, Scott R. Ceresnak, Garbine Goya, Lanier B. Jackson, Tam Dan N. Pham, Source Type: research

Antipsychotic Use and Risk of Breast Cancer in Women With Severe Mental Illness: Replication of a Nationwide Nested Case-Control Database Study
CONCLUSIONS: Although causality remains uncertain, exposure to prolactin-elevating antipsychotics for ≥ 1 year was associated with increased odds of breast cancer in women with severe mental illness. When prescribing antipsychotics, a shared decision-making process should consider individual risk factors for breast cancer.PMID:38687213 | DOI:10.1093/schbul/sbae058 (Source: Cancer Control)
Source: Cancer Control - April 30, 2024 Category: Cancer & Oncology Authors: Marco Solmi Markku L ähteenvuo Antti Tanskanen Olivier Corbeil Ellenor Mittendorfer-Rutz Christoph U Correll Jari Tiihonen Heidi Taipale Source Type: research

Velocity-compensated intravoxel incoherent motion of the human calf muscle
CONCLUSION: Velocity-compensated diffusion gradients significantly suppress the IVIM effect in the calf muscle, indicating that the ballistic limit is mostly reached, which is supported by the time dependence of the pseudo-diffusion coefficient.PMID:38688865 | DOI:10.1002/mrm.30059 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - April 30, 2024 Category: Radiology Authors: Christoph M Stuprich Martin Loh Johannes T Nemerth Armin M Nagel Michael Uder Frederik B Laun Source Type: research

Predictors of long-term mortality in older patients with hip fractures managed by hemiarthroplasty: a 10-year study based on a population registry in Saxony, Germany
CONCLUSIONS: In the present study based on data from the population registry from Saxony, Germany the 10-year mortality of older patients above 60 years of age managed with hemiarthroplasty for femoral neck fracture was 80%. Independent risk factors for increased long-term mortality were higher patient age, male gender, severe comorbidity, a history of cancer and in particular dementia. Perioperative factors did not affect long-term mortality.PMID:38689330 | DOI:10.1186/s13037-024-00398-9 (Source: Patient Safety in Surgery)
Source: Patient Safety in Surgery - April 30, 2024 Category: Surgery Authors: Johannes K M Fakler Philipp Pieroh Andreas H öch Andreas Roth Christian Kleber Markus L öffler Christoph E Heyde Samira Zeynalova Source Type: research

Purely Organic Room-Temperature Phosphorescence Molecule for High-Performance Non-Doped Organic Light-Emitting Diodes
Angew Chem Int Ed Engl. 2024 Apr 30:e202405418. doi: 10.1002/anie.202405418. Online ahead of print.ABSTRACTPurely organic molecules with room-temperature phosphorescence (RTP) are potential luminescent materials with high exciton utilization for organic light-emitting diodes (OLEDs), but those exhibiting superb electroluminescence (EL) performances are rarely explored, mainly due to their long phosphorescence lifetimes. Herein, a robust purely organic RTP molecule, 3,6-bis(5-phenylindolo[3,2-a]carbazol-12(5H)-yl)-xanthen-9-one (3,2-PIC-XT), is developed. The neat film of 3,2-PIC-XT shows strong green RTP with a very short ...
Source: Angewandte Chemie - April 30, 2024 Category: Chemistry Authors: Xiaoluo Peng Peng Zou Jiajie Zeng Xing Wu Dian Xie Yan Fu Dezhi Yang Dongge Ma Ben Zhong Tang Zujin Zhao Source Type: research

Velocity-compensated intravoxel incoherent motion of the human calf muscle
CONCLUSION: Velocity-compensated diffusion gradients significantly suppress the IVIM effect in the calf muscle, indicating that the ballistic limit is mostly reached, which is supported by the time dependence of the pseudo-diffusion coefficient.PMID:38688865 | DOI:10.1002/mrm.30059 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - April 30, 2024 Category: Radiology Authors: Christoph M Stuprich Martin Loh Johannes T Nemerth Armin M Nagel Michael Uder Frederik B Laun Source Type: research

Predictors of long-term mortality in older patients with hip fractures managed by hemiarthroplasty: a 10-year study based on a population registry in Saxony, Germany
CONCLUSIONS: In the present study based on data from the population registry from Saxony, Germany the 10-year mortality of older patients above 60 years of age managed with hemiarthroplasty for femoral neck fracture was 80%. Independent risk factors for increased long-term mortality were higher patient age, male gender, severe comorbidity, a history of cancer and in particular dementia. Perioperative factors did not affect long-term mortality.PMID:38689330 | DOI:10.1186/s13037-024-00398-9 (Source: Patient Safety in Surgery)
Source: Patient Safety in Surgery - April 30, 2024 Category: Surgery Authors: Johannes K M Fakler Philipp Pieroh Andreas H öch Andreas Roth Christian Kleber Markus L öffler Christoph E Heyde Samira Zeynalova Source Type: research

Velocity-compensated intravoxel incoherent motion of the human calf muscle
CONCLUSION: Velocity-compensated diffusion gradients significantly suppress the IVIM effect in the calf muscle, indicating that the ballistic limit is mostly reached, which is supported by the time dependence of the pseudo-diffusion coefficient.PMID:38688865 | DOI:10.1002/mrm.30059 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - April 30, 2024 Category: Radiology Authors: Christoph M Stuprich Martin Loh Johannes T Nemerth Armin M Nagel Michael Uder Frederik B Laun Source Type: research

Predictors of long-term mortality in older patients with hip fractures managed by hemiarthroplasty: a 10-year study based on a population registry in Saxony, Germany
CONCLUSIONS: In the present study based on data from the population registry from Saxony, Germany the 10-year mortality of older patients above 60 years of age managed with hemiarthroplasty for femoral neck fracture was 80%. Independent risk factors for increased long-term mortality were higher patient age, male gender, severe comorbidity, a history of cancer and in particular dementia. Perioperative factors did not affect long-term mortality.PMID:38689330 | PMC:PMC11061946 | DOI:10.1186/s13037-024-00398-9 (Source: Patient Safety in Surgery)
Source: Patient Safety in Surgery - April 30, 2024 Category: Surgery Authors: Johannes K M Fakler Philipp Pieroh Andreas H öch Andreas Roth Christian Kleber Markus L öffler Christoph E Heyde Samira Zeynalova Source Type: research