Bipolar disorder staging and the impact it has on its management: an update
Expert Rev Neurother. 2024 May 16:1-10. doi: 10.1080/14737175.2024.2355264. Online ahead of print.ABSTRACTINTRODUCTION: The longitudinal course of bipolar disorder (BD) is associated with an active process of neuroprogression, characterized by structural brain alterations and progressive functional impairment. In the last decades, a growing need of a standardized staging model for BD arose, with the aim of a more appropriate definition of stage-specific clinical manifestations and the identification of more customized therapeutic tools.AREAS COVERED: The authors review the literature on clinical aspects, neurobiological co...
Source: Expert Review of Neurotherapeutics - May 16, 2024 Category: Neurology Authors: Bernardo Dell'Osso Laura Cremaschi Monica Macellaro Rita Cafaro Nicolaja Girone Source Type: research