DRESS as a rare differential diagnosis in eosinophilia, skin rash and acute hepatitis
Z Gastroenterol. 2024 May 15. doi: 10.1055/a-2300-0620. Online ahead of print.ABSTRACTA 21-year-old female patient presented with fever, pharyngitis, lymphadenopathy and generalized exanthema that had started 2 weeks prior. Allergies were not known, the family and travel history were negative. Due to depression, Duloxetine had been taken for 1.5 years, and due to bipolar disorder, a treatment with Lamotrigine was started four weeks prior but was stopped because of increased transaminase levels. Laboratory findings on admission showed eosinophilia (1.327 /nl), lymphocytosis and acute hepatitis (GOT 428 U/l, GPT 438 U/l) wit...
Source: Zeitschrift fur Gastroenterologie - May 15, 2024 Category: Gastroenterology Authors: Daniela Prechal David Arntzen Lioba Klaas Maren Paulmann Maja Mockenhaupt Robert Thimme Marcus Schuchmann Source Type: research

Connections between specific mental health diagnoses of schizophrenia, bipolar disorder and schizoaffective disorder and primary substance use
This study aims to use the database of consumers referred to the dual diagnosis shared care service to examine those connections. The Eastern Dual Diagnosis Service, based in Melbourne, Australia, has established a database of consumers with co-occurring mental health disorders and problematic substance use. An examination of mental health and substance-use information obtained over a two-year period in the delivery of dual diagnosis shared care to consumers of mental health services is supporting an improved understanding of substance use and the connections to specific mental health diagnoses of schizophrenia, bipolar di...
Source: Advances in Dual Diagnosis - May 15, 2024 Category: Psychiatry Authors: Gavin Foster David Taylor Stephanie Gough Source Type: research

Machine learning algorithm predicts urethral stricture following transurethral prostate resection
ConclusionOur machine learning models ’ accuracy in predicting the post-TURP urethral stricture probability has demonstrated significant success. Exploring prospective studies that integrate supplementary variables has the potential to enhance the precision and accuracy of machine learning models, consequently progressing their abilit y to predict post-TURP urethral stricture risk. (Source: World Journal of Urology)
Source: World Journal of Urology - May 15, 2024 Category: Urology & Nephrology Source Type: research

Editorial: Combining Genetic and Clinical Predictors of Bipolar Disorder: Towards Improving the Diagnostic Precision in Youth
Bipolar disorder (BD) is a complex heterogeneous illness, with 60-85% of its variance attributed to genetic factors.1 Adolescence marks the first peak period of risk for the onset of BD, with the initial (hypo)manic episode often preceded by childhood psychopathology, including anxiety and sleep disorders, as well as internalizing symptoms.2 Given the non-specific nature of childhood antecedents, combined with the prominence of depressive episodes in the early illness course, accurate diagnosis is often delayed by 8-10 years from onset. (Source: Journal of the American Academy of Child and Adolescent Psychiatry)
Source: Journal of the American Academy of Child and Adolescent Psychiatry - May 15, 2024 Category: Psychiatry Authors: En-Nien Tu, Anne Duffy Tags: Editorial Source Type: research

Lithium-discontinuation-induced treatment refractoriness revisited
Lithium is effective in the long-term treatment of bipolar disorder. Concerns have been raised about non-responsiveness after discontinuation and resuming previously effective lithium prophylaxis. We reviewed ... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - May 15, 2024 Category: Psychiatry Authors: Ralph Kupka, Eline Regeer, Annet van Bergen, Leonardo Tondo and Michael Bauer Tags: Review Source Type: research

Approche de la d écision partagée concernant la prise en charge du diabète de type 2
CONCLUSION: L’aide à la décision sur la médication pour le diabète offre un outil pratique qui peut permettre aux patients de prendre des décisions bien éclairées et de manière autonome sur les médicaments.PMID:38744515 | DOI:10.46747/cfp.7005316 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - May 14, 2024 Category: Primary Care Authors: Blair J MacDonald James P McCormack Ricky D Turgeon Source Type: research

Morphology, morphogenesis and molecular phylogeny of a new soil ciliate, Lamtostyla paravitiphila nov. spec. (Ciliophora, Hypotrichia)
Eur J Protistol. 2024 May 2;94:126088. doi: 10.1016/j.ejop.2024.126088. Online ahead of print.ABSTRACTThe morphology and morphogenesis of Lamtostyla paravitiphila nov. spec., a novel soil hypotrichous ciliate collected from eastern China, were investigated based on live observations and protargol-stained specimens. The new species is morphologically characterized as follows: seven to twelve macronuclear nodules, cortical granules absent, 19-26 adoral membranelles, three or four frontoventral cirri, the amphisiellid median cirral row extends to about mid-body and composed of 12-18 cirri, two or three transverse cirri, 27-39...
Source: European Journal of Protistology - May 14, 2024 Category: Microbiology Authors: Tengteng Zhang Furui Lu Xiaoqing Yang Yurui Wang Chen Shao Source Type: research

Approche de la d écision partagée concernant la prise en charge du diabète de type 2
CONCLUSION: L’aide à la décision sur la médication pour le diabète offre un outil pratique qui peut permettre aux patients de prendre des décisions bien éclairées et de manière autonome sur les médicaments.PMID:38744515 | DOI:10.46747/cfp.7005316 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - May 14, 2024 Category: Primary Care Authors: Blair J MacDonald James P McCormack Ricky D Turgeon Source Type: research

Approche de la d écision partagée concernant la prise en charge du diabète de type 2
CONCLUSION: L’aide à la décision sur la médication pour le diabète offre un outil pratique qui peut permettre aux patients de prendre des décisions bien éclairées et de manière autonome sur les médicaments.PMID:38744515 | DOI:10.46747/cfp.7005316 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - May 14, 2024 Category: Primary Care Authors: Blair J MacDonald James P McCormack Ricky D Turgeon Source Type: research

Approche de la d écision partagée concernant la prise en charge du diabète de type 2
CONCLUSION: L’aide à la décision sur la médication pour le diabète offre un outil pratique qui peut permettre aux patients de prendre des décisions bien éclairées et de manière autonome sur les médicaments.PMID:38744515 | DOI:10.46747/cfp.7005316 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - May 14, 2024 Category: Primary Care Authors: Blair J MacDonald James P McCormack Ricky D Turgeon Source Type: research

Shared and distinct electroencephalogram microstate abnormalities across schizophrenia, bipolar disorder, and depression
CONCLUSIONS: Our findings provide crucial insights into the abnormalities involved in distributing neural assets and enabling proper transitions between different microstates in patients with major psychiatric disorders.PMID:38738283 | DOI:10.1017/S0033291724001132 (Source: Psychological Medicine)
Source: Psychological Medicine - May 13, 2024 Category: Psychiatry Authors: Rui Xue Xiaojing Li Wei Deng Chengqian Liang Mingxia Chen Jianning Chen Sugai Liang Wei Wei Yamin Zhang Hua Yu Yan Xu Wanjun Guo Tao Li Source Type: research

Shared and distinct electroencephalogram microstate abnormalities across schizophrenia, bipolar disorder, and depression
CONCLUSIONS: Our findings provide crucial insights into the abnormalities involved in distributing neural assets and enabling proper transitions between different microstates in patients with major psychiatric disorders.PMID:38738283 | DOI:10.1017/S0033291724001132 (Source: Psychological Medicine)
Source: Psychological Medicine - May 13, 2024 Category: Psychiatry Authors: Rui Xue Xiaojing Li Wei Deng Chengqian Liang Mingxia Chen Jianning Chen Sugai Liang Wei Wei Yamin Zhang Hua Yu Yan Xu Wanjun Guo Tao Li Source Type: research

Shared and distinct electroencephalogram microstate abnormalities across schizophrenia, bipolar disorder, and depression
CONCLUSIONS: Our findings provide crucial insights into the abnormalities involved in distributing neural assets and enabling proper transitions between different microstates in patients with major psychiatric disorders.PMID:38738283 | DOI:10.1017/S0033291724001132 (Source: Psychological Medicine)
Source: Psychological Medicine - May 13, 2024 Category: Psychiatry Authors: Rui Xue Xiaojing Li Wei Deng Chengqian Liang Mingxia Chen Jianning Chen Sugai Liang Wei Wei Yamin Zhang Hua Yu Yan Xu Wanjun Guo Tao Li Source Type: research

Shared and distinct electroencephalogram microstate abnormalities across schizophrenia, bipolar disorder, and depression
CONCLUSIONS: Our findings provide crucial insights into the abnormalities involved in distributing neural assets and enabling proper transitions between different microstates in patients with major psychiatric disorders.PMID:38738283 | DOI:10.1017/S0033291724001132 (Source: Psychological Medicine)
Source: Psychological Medicine - May 13, 2024 Category: Psychiatry Authors: Rui Xue Xiaojing Li Wei Deng Chengqian Liang Mingxia Chen Jianning Chen Sugai Liang Wei Wei Yamin Zhang Hua Yu Yan Xu Wanjun Guo Tao Li Source Type: research

Association of intestinal anti-inflammatory drug target genes with psychiatric Disorders: A Mendelian randomization study
CONCLUSION: These findings provide novel targets for the treatment of psychiatric disorders, underscore the potential of repurposing olsalazine, and emphasize the importance of TPMT and ACAT1 in future drug development.PMID:38735387 | DOI:10.1016/j.jare.2024.05.002 (Source: Adv Data)
Source: Adv Data - May 12, 2024 Category: Epidemiology Authors: Guorui Zhao Zhe Lu Yundan Liao Yaoyao Sun Yuyanan Zhang Zhewei Kang Xiaoyang Feng Junyuan Sun Weihua Yue Source Type: research