Reliability and validity of the functioning assessment short test for older adults with bipolar disorder (FAST-O)
Many frequently used instruments fail to assess psychosocial functioning in patients with bipolar disorder. The Functioning Assessment Short Test (FAST) was developed in order to tackle this problem and to ass... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - October 2, 2020 Category: Psychiatry Authors: Melis Orhan, Nicole Korten, Ralph Kupka, Patricia van Oppen, Max Stek, Eduard Vieta, Sigfried Schouws, Wouter van Ballegooijen and Annemiek Dols Tags: Research Source Type: research

A multi-center naturalistic study of a newly designed 12-sessions group psychoeducation program for patients with bipolar disorder and their caregivers
Psychoeducation (PE) for bipolar disorder (BD) has a first-line recommendation for the maintenance treatment phase of BD. Formats vary greatly in the number of sessions, whether offered individually or in a gr... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - September 1, 2020 Category: Psychiatry Authors: Susan Zyto, Nienke Jabben, Peter F. J. Schulte, Eline J. Regeer, Peter J. J. Goossens and Ralph W. Kupka Tags: Research Source Type: research

Bipolar offspring and mothers: interactional challenges at infant age 3 and 12 months —a developmental pathway to enhanced risk?
Bipolar offspring are considered a high-risk group for developing mental disorders. Developmental outcomes result from additive and interactive effects of biological vulnerability and environmental influences.... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - August 31, 2020 Category: Psychiatry Authors: Teija M. S. Anke, Kari Slinning, Vibeke Moe, Cathrine Brunborg, Torill S. Siqveland and Dag Vegard Skjelstad Tags: Research Source Type: research

FAB: First UK feasibility trial of a future randomised controlled trial of Family focused treatment for Adolescents with Bipolar disorder
This first mixed-methods UK trial examined the feasibility and acceptability of a future definitive randomised controlled trial (RCT) to evaluate whether Family Focussed Treatment for Adolescents with Bipolar ... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - August 3, 2020 Category: Psychiatry Authors: A. Sharma, M. Glod, T. Forster, R. McGovern, K. McGurk, E. Barron Millar, T. D. Meyer, D. Miklowitz, V. Ryan, L. Vale and A. Le Couteur Tags: Research Source Type: research

Low-dose lithium against dementia
(Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - August 3, 2020 Category: Psychiatry Authors: Christopher Baethge Tags: Letter to the Editor Source Type: research

Potential pharmacogenomic targets in bipolar disorder: considerations for current testing and the development of decision support tools to individualize treatment selection
Treatment in bipolar disorder (BD) is commonly applied as a multimodal therapy based on decision algorithms that lack an integrative understanding of molecular mechanisms or a biomarker associated clinical out... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - July 4, 2020 Category: Psychiatry Authors: Alfredo B. Cu éllar-Barboza, Susan L. McElroy, Marin Veldic, Balwinder Singh, Simon Kung, Francisco Romo-Nava, Nicolas A. Nunez, Alejandra Cabello-Arreola, Brandon J. Coombes, Miguel Prieto, Hannah K. Betcher, Katherine M. Moore, Stacey J. Winham, Joanna Tags: Review Source Type: research

Improving early recognition and intervention in people at increased risk for the development of bipolar disorder: study protocol of a prospective-longitudinal, naturalistic cohort study (Early-BipoLife)
Bipolar disorders (BD) belong to the most severe mental disorders, characterized by an early onset and recurrent, severe episodes or a chronic course with poor psychosocial functioning in a proportion of patie... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - July 1, 2020 Category: Psychiatry Authors: Andrea Pfennig, Karolina Leopold, Julia Martini, Anne Boehme, Martin Lambert, Thomas Stamm, Felix Bermpohl, Andreas Reif, Sarah Kittel-Schneider, Georg Juckel, Andreas J. Fallgatter, Tilo Kircher, Andreas Jansen, Steffi Pfeiffer, Christina Berndt, Maren R Tags: Study Protocols Source Type: research

Sleep and physical activity in patients with newly diagnosed bipolar disorder in remission, their first-degree unaffected relatives and healthy controls
Sleep disturbances are a central feature in bipolar disorder (BD) that often persist in remission and seem to be present also in unaffected first-degree relatives (UR) of patients with BD, presenting a possibl... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - June 1, 2020 Category: Psychiatry Authors: Nikolaj Folke la Cour Karottki, Klara Coello, Sharleny Stanislaus, Sigurd Melbye, Hanne Lie Kj ærstad, Kimie Stefanie Ormstrup Sletved, Lars Vedel Kessing and Maj Vinberg Tags: Research Source Type: research

Treating winter depressive episodes in bipolar disorder: an open trial of light therapy
Light therapy has been used to treat winter depression in bipolar disorder, although the dose, duration, and timing of treatment have differed. The present study is an open trial of light therapy for depressiv... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - June 1, 2020 Category: Psychiatry Authors: Lotte J. E. van Hout, Lisette E. P. Rops and Claudia J. P. Simons Tags: Short Communication Source Type: research

Lithium ’s antiviral effects: a potential drug for CoViD-19 disease?
Since its introduction in modern medicine, naturalistic observations emerged about possible uses of lithium treatment for conditions different from recurring affective disorders, for which it is still a first-... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - May 20, 2020 Category: Psychiatry Authors: Andrea Murru, Mirko Manchia, Tomas Hajek, Ren é E. Nielsen, Janusz K. Rybakowski, Gabriele Sani, Thomas G. Schulze, Leonardo Tondo and Michael Bauer Tags: Review Source Type: research

Diagnostic stability in children and adolescents with bipolar disorder, a nationwide register-based study
Diagnostic stability of bipolar disorder (BD) in children and adolescents, beyond the first contact has been investigated sparsely. The aim of this study was to investigate the diagnostic stability of BD in ch... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - May 6, 2020 Category: Psychiatry Authors: Mathilde Frahm Laursen, Rasmus W. Licht, Christoph U. Correll, Tobias Kallehauge, Ann-Eva Christensen, Maria Rodrigo-Domingo and Ren é Ernst Nielsen Tags: Research Source Type: research

The effects of vagus nerve stimulation on the course and outcomes of patients with bipolar disorder in a treatment-resistant depressive episode: a 5-year prospective registry
To compare illness characteristics, treatment history, response and durability, and suicidality scores over a 5-year period in patients with treatment-resistant bipolar depression participating in a prospectiv... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - May 2, 2020 Category: Psychiatry Authors: R. Hamish McAllister-Williams, Soraia Sousa, Arun Kumar, Teresa Greco, Mark T. Bunker, Scott T. Aaronson, Charles R. Conway and A. John Rush Tags: Research Source Type: research

Pre-pubertal bipolar disorder: origins and current status of the controversy
Evidence from epidemiological, clinical and high-risk studies has established that the peak period of risk for onset of bipolar disorder spans late adolescence and early adulthood. However, the proposal of the... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - April 20, 2020 Category: Psychiatry Authors: A. Duffy, G. Carlson, B. Dubicka and M. H. J. Hillegers Tags: Review Source Type: research

Reflections on: "The diagnosis of bipolar disorder in pre-pubertal children —what was the controversy about and what did we learn as a result?"
It can be argued that the controversy over paediatric bipolar disorder has been useful in highlighting the issue of bipolar disorder in youths generally. Arising out of this controversy is the recognition that... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - April 20, 2020 Category: Psychiatry Authors: Anthony James Tags: Letter to the Editor Source Type: research

Prepubertal bipolar disorder: a diagnostic quandary?
(Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - April 20, 2020 Category: Psychiatry Authors: Gin S. Malhi and Erica Bell Tags: Letter to the Editor Source Type: research

Mixed mood states and emotion-related urgency in bipolar spectrum disorders: a call for greater investigation
(Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - March 5, 2020 Category: Psychiatry Authors: Jennie A. Jaggers and June Gruber Tags: Letter to the Editor Source Type: research

Cortisol levels in unmedicated patients with unipolar and bipolar major depression using hair and saliva specimens
Differentiating between unipolar and bipolar depression can be clinically challenging, especially at first presentation. Patterns of cortisol secretion could aid diagnostic discrimination in affective disorder... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - March 5, 2020 Category: Psychiatry Authors: Andr és Herane-Vives, Danilo Arnone, Valeria de Angel, Andrew Papadopoulos, Toby Wise, Luis Alameda, Kia-Chong Chua, Allan H. Young and Anthony J. Cleare Tags: Research Source Type: research

Role of child maltreatment and gender for bipolar symptoms in young adults
Child maltreatment has been shown to be associated with a wide range of mental disorders, including bipolar disorders. In this 2-year follow-up study, recollections of emotional, physical and sexual abuse were... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - March 2, 2020 Category: Psychiatry Authors: Ida S. Haussleiter, Eva Neumann, Sandra Lorek, Bianca Ueberberg and Georg Juckel Tags: Research Source Type: research

Combination of dextromethorphan and memantine in treating bipolar spectrum disorder: a 12-week double-blind randomized clinical trial
The aim of this study is to determine whether adding combination of agents with anti-inflammatory and neurotrophic effects is more efficacious than mood stabilizer alone in improving clinical symptoms, plasma ... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - March 2, 2020 Category: Psychiatry Authors: Sheng-Yu Lee, Tzu-Yun Wang, Shiou-Lan Chen, Yun-Hsuan Chang, Po-See Chen, San-Yuan Huang, Nian-Sheng Tzeng, Liang-Jen Wang, I-Hui Lee, Kao-Ching Chen, Yen-Kuang Yang, Jau-Shyong Hong and Ru-Band Lu Tags: Research Source Type: research

The role of environmental stress and DNA methylation in the longitudinal course of bipolar disorder
Stressful life events influence the course of affective disorders, however, the mechanisms by which they bring about phenotypic change are not entirely known. (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - February 12, 2020 Category: Psychiatry Authors: Ashley L. Comes, Darina Czamara, Kristina Adorjan, Heike Anderson-Schmidt, Till F. M. Andlauer, Monika Budde, Katrin Gade, Maria Hake, Janos L. Kalman, Sergi Papiol, Daniela Reich-Erkelenz, Farah Kl öhn-Saghatolislam, Sabrina K. Schaupp, Eva C. Schulte, Tags: Research Source Type: research

A comprehensive assessment of personality traits and psychosocial functioning in parents with bipolar disorder and their intimate partners
Individuals with bipolar disorder (BD) often possess maladaptive traits and present with various difficulties in psychosocial functioning. However, little is known about the intimate partners of adults with bi... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - February 10, 2020 Category: Psychiatry Authors: Lisa Serravalle, Vanessa Iacono, Sheilagh Hodgins and Mark A. Ellenbogen Tags: Research Source Type: research

Executive functioning but not IQ or illness severity predicts occupational status in bipolar disorder
Bipolar disorder is associated with significant functional deficits including occupational functioning. Despite the high rates of unemployment and sick leave in the patient population, only a limited number of... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - February 7, 2020 Category: Psychiatry Authors: Julia Drakopoulos, Timea Sparding, Caitlin Clements, Erik P ålsson and Mikael Landén Tags: Research Source Type: research

An integrative analysis of genome-wide association study and regulatory SNP annotation datasets identified candidate genes for bipolar disorder
Bipolar disorder (BD) is a complex mood disorder. The genetic mechanism of BD remains largely unknown. (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - February 3, 2020 Category: Psychiatry Authors: Xin Qi, Yan Wen, Ping Li, Chujun Liang, Bolun Cheng, Mei Ma, Shiqiang Cheng, Lu Zhang, Li Liu, Om Prakash Kafle and Feng Zhang Tags: Research Source Type: research

The existential crisis of bipolar II disorder
The issue of categorical vs. dimensional classification of bipolar disorder continues to generate controversy as it has for generations. Despite the evidence that no psychiatric disorder has discrete boundarie... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - January 28, 2020 Category: Psychiatry Authors: Michael Gitlin and Gin S. Malhi Tags: Review Source Type: research

Bipolar disorders in ICD-11: current status and strengths
The Clinical descriptions and diagnostic guidelines for the ICD-11 Classification of mental and behavioural disorders should soon be finalized. To measure their potential impact, the new proposed definitions o... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - January 20, 2020 Category: Psychiatry Authors: Jules Angst, Vladeta Ajdacic-Gross and Wulf R össler Tags: Short Communication Source Type: research

Diagnosing bipolar disorders: ICD-11 and beyond
(Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - January 20, 2020 Category: Psychiatry Authors: Emanuel Severus and Michael Bauer Tags: Editorial Source Type: research

Smartphones in mental health: a critical review of background issues, current status and future concerns
There has been increasing interest in the use of smartphone applications (apps) and other consumer technology in mental health care for a number of years. However, the vision of data from apps seamlessly retur... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - January 10, 2020 Category: Psychiatry Authors: Michael Bauer, Tasha Glenn, John Geddes, Michael Gitlin, Paul Grof, Lars V. Kessing, Scott Monteith, Maria Faurholt-Jepsen, Emanuel Severus and Peter C. Whybrow Tags: Review Source Type: research

Bipolar depression: a major unsolved challenge
Depression in bipolar disorder (BD) patients presents major clinical challenges. As the predominant psychopathology even in treated BD, depression is associated not only with excess morbidity, but also mortali... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - January 6, 2020 Category: Psychiatry Authors: Ross J. Baldessarini, Gustavo H. V ázquez and Leonardo Tondo Tags: Review Source Type: research

Guides for users and prescribers of lithium
(Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - December 23, 2019 Category: Psychiatry Authors: Janusz K. Rybakowski Tags: Letter to the Editor Source Type: research

Predictors of psychosocial outcome of bipolar disorder: data from the Stanley Foundation Bipolar Network
Impairments in psychosocial functioning have been demonstrated in 30 –60% of adults with bipolar disorder (BD). However, the majority of studies investigating the effect of comorbid mental health disorders and ... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - December 16, 2019 Category: Psychiatry Authors: Francis Bennett, Sophie Hodgetts, Andrew Close, Mark Frye, Heinz Grunze, Paul Keck, Ralph Kupka, Susan McElroy, Willem Nolen, Robert Post, Lars Sch ärer, Trisha Suppes and Aditya N. Sharma Tags: Research Source Type: research

Investigating the relationship between melatonin levels, melatonin system, microbiota composition and bipolar disorder psychopathology across the different phases of the disease
Bipolar disorder (BD) is characterized by recurrent episodes of depression and mania/hypomania alternating with intervals of well-being. The neurobiological underpinnings of BD are still veiled although there ... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - December 9, 2019 Category: Psychiatry Authors: Mirko Manchia, Alessio Squassina, Claudia Pisanu, Donatella Congiu, Mario Garzilli, Beatrice Guiso, Federico Suprani, Pasquale Paribello, Vittoria Pulcinelli, Maria Novella Iaselli, Federica Pinna, Flavia Valtorta, Bernardo Carpiniello and Stefano Comai Tags: Study Protocols Source Type: research

C-reactive protein concentration in bipolar disorder: association with genetic variants
Several recent studies have investigated the role of C-reactive protein (CRP) in bipolar disorder (BD), but few studies have directly investigated the interaction between CRP genetic variants and peripheral CRP c... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - December 2, 2019 Category: Psychiatry Authors: Ann-Kristin Evers, Julia Veeh, Rhiannon McNeill, Andreas Reif and Sarah Kittel-Schneider Tags: Research Source Type: research

Association between decreased HDL levels and cognitive deficits in patients with bipolar disorder: a pilot study
Cognitive deficits are common in patients with bipolar disorder (BD). Abnormal high density lipoprotein (HDL) levels have been implicated in cognitive deficits associated with ageing and neurodegenerative diso... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - November 25, 2019 Category: Psychiatry Authors: Li Hui, Xiao Li Yin, Jie Chen, Xu Yuan Yin, Hong Liang Zhu, Jin Li, Guang Zhong Yin, Xiao Wen Xu, Xiao Nan Yang, Zheng Kang Qian, Cai Xia Jiang, Zhen Tang, Hai Bing Yang, Eric F. C. Cheung, Raymond C. K. Chan and Qiu Fang Jia Tags: Research Source Type: research

Alterations of perineuronal nets in the dorsolateral prefrontal cortex of neuropsychiatric patients
Alterations in the structure and physiology of interneurons in the prefrontal cortex (PFC) are important factors in the etiopathology of different psychiatric disorders. Among the interneuronal subpopulations,... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - November 15, 2019 Category: Psychiatry Authors: Julia Alcaide, Ram ón Guirado, Carlos Crespo, José Miguel Blasco-Ibáñez, Emilio Varea, Julio Sanjuan and Juan Nacher Tags: Research Source Type: research

Short group psychoeducation followed by daily electronic self-monitoring in the long-term treatment of bipolar disorders: a multicenter, rater-blind, randomized controlled trial
Despite various pharmacological and psychological treatment interventions, bipolar disorders rank among the leading causes of global disease burden. Group psychoeducation has been demonstrated an effective add... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - November 4, 2019 Category: Psychiatry Authors: Johannes Petzold, Ren é Mayer-Pelinski, Maximilian Pilhatsch, Susan Luthe, Thomas Barth, Michael Bauer and Emanuel Severus Tags: Research Source Type: research

Investigating the association between anxiety symptoms and mood disorder in high-risk offspring of bipolar parents: a comparison of Joint and Cox models
Anxiety is associated with mood disorders including bipolar disorder. Two statistical modelling frameworks were compared to investigate the longitudinal relationship between repeatedly measured anxiety symptom... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - October 18, 2019 Category: Psychiatry Authors: Ruoxi Dong, George Stefan, Julie Horrocks, Sarah M. Goodday and Anne Duffy Tags: Research Source Type: research

Treatment of bipolar depression with supraphysiologic doses of levothyroxine: a randomized, placebo-controlled study of comorbid anxiety symptoms
Symptoms of anxiety co-occur in a variety of disorders including in depressive episodes of bipolar disorder and in patients with thyrotoxicosis. Treatment of refractory bipolar disorder with supraphysiologic d... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - October 4, 2019 Category: Psychiatry Authors: Maximilian Pilhatsch, Thomas J Stamm, Petra Stahl, Ute Lewitzka, Anne Bergh öfer, Cathrin Sauer, Michael Gitlin, Mark A. Frye, Peter C. Whybrow and Michael Bauer Tags: Research Source Type: research

Prospective cohort study of early biosignatures of response to lithium in bipolar-I-disorders: overview of the H2020-funded R-LiNK initiative
Lithium is recommended as a first line treatment for bipolar disorders. However, only 30% of patients show an optimal outcome and variability in lithium response and tolerability is poorly understood. It remai... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - September 25, 2019 Category: Psychiatry Authors: Jan Scott, Diego Hidalgo-Mazzei, Rebecca Strawbridge, Allan Young, Matthieu Resche-Rigon, Bruno Etain, Ole A. Andreassen, Michael Bauer, Djamila Bennabi, Andrew M. Blamire, Fawzi Boumezbeur, Paolo Brambilla, Nadia Cattane, Annamaria Cattaneo, Marie Chupin Tags: Review Source Type: research

Trajectories of adherence to mood stabilizers in patients with bipolar disorder
Nonadherence with mood stabilizers is a major problem that negatively impacts the course of bipolar disorder. Medication adherence is a complex individual behavior, and adherence rates often change over time. ... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - September 4, 2019 Category: Psychiatry Authors: M. Bauer, T. Glenn, M. Alda, R. Bauer, P. Grof, W. Marsh, S. Monteith, R. Munoz, N. Rasgon, K. Sagduyu and P. C. Whybrow Tags: Research Source Type: research

Exploring the clinical outcome of Mindfulness-Based Cognitive Therapy for bipolar and unipolar depressive patients in routine clinical practice: a pilot study
Mindfulness Based Cognitive Therapy (MBCT) has been adopted as an evidence-based treatment for unipolar depressive disorder (UDD). Although MBCT has not been included in the treatment guidelines for bipolar di... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - August 28, 2019 Category: Psychiatry Authors: I. Hanssen, M. I. van Dord, F. R. Compen, D. E. M. Geurts, M. P. J. Schellekens and A. E. M. Speckens Tags: Research Source Type: research

Epigenetic markers in inflammation-related genes associated with mood disorder: a cross-sectional and longitudinal study in high-risk offspring of bipolar parents
Bipolar disorder is highly heritable and typically onsets in late adolescence or early adulthood. Evidence suggests that immune activation may be a mediating pathway between genetic predisposition and onset of... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - August 6, 2019 Category: Psychiatry Authors: Anne Duffy, Sarah M. Goodday, Charles Keown-Stoneman, Martina Scotti, Malosree Maitra, Corina Nagy, Julie Horrocks and Gustavo Turecki Tags: Short communication Source Type: research

Clinical use of lithium salts: guide for users and prescribers
Lithium has been used clinically for 70 years, mainly to treat bipolar disorder. Competing treatments and exaggerated impressions about complexity and risks of lithium treatment have led to its declining use i... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - July 22, 2019 Category: Psychiatry Authors: Leonardo Tondo, Martin Alda, Michael Bauer, Veerle Bergink, Paul Grof, Tomas Hajek, Ute Lewitka, Rasmus W. Licht, Mirko Manchia, Bruno M üller-Oerlinghausen, René E. Nielsen, Marylou Selo, Christian Simhandl and Ross J. Baldessarini Tags: Review Source Type: research

Alec J. Coppen —A pioneering psychiatrist who discovered the pivotal role of serotonin in the pathogenesis of depression as well as the antisuicidal effect of lithium
(Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - July 2, 2019 Category: Psychiatry Authors: Bruno M üller-Oerlinghausen and Mohammed T. Abou-Saleh Tags: Editorial Source Type: research

Neuropsychological profiles of adult bipolar disorder patients with and without comorbid attention-deficit hyperactivity disorder
Comorbid attention-deficit/hyperactivity disorder (ADHD) is common in bipolar disorder and associated with worse outcomes. Cognitive testing might be a tool to identify this group. Here we compare the neuropsy... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - June 28, 2019 Category: Psychiatry Authors: Sara Salarvan, Timea Sparding, Caitlin Clements, Eleonore Ryd én and Mikael Landén Tags: Research Source Type: research

Attenuated inflammatory response of monocyte-derived macrophage from patients with BD: a preliminary report
Innate immune system dysfunction has been recognized as an important element in the pathophysiology of bipolar disorder (BD). We aimed to investigate whether there are differences in the response of macrophage... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - June 1, 2019 Category: Psychiatry Authors: Bruna M. Ascoli, Mariana M. Parisi, Giovana Bristot, B árbara Antqueviezc, Luiza P. Géa, Rafael Colombo, Flávio Kapczinski, Fátima Theresinha Costa Rodrigues Guma, Elisa Brietzke, Florencia M. Barbé-Tuana and Adriane R. Rosa Tags: Research Source Type: research

Why are somatic diseases in bipolar disorder insufficiently treated?
Somatic diseases, including cardiovascular, respiratory, and cancer diseases, are the main contributors to a shortened life expectancy of 10 –20 years in patients with bipolar disorder as compared to the genera... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - May 5, 2019 Category: Psychiatry Authors: Ren é Ernst Nielsen, Pirathiv Kugathasan, Sune Straszek, Svend Eggert Jensen and Rasmus W. Licht Tags: Review Source Type: research

Electroconvulsive therapy electrode placement for bipolar state-related targeted engagement
Electroconvulsive therapy (ECT) is an effective treatment for all bipolar states. However, ECT remains underutilized, likely stemming from stigma and the risk of neurocognitive impairment. Neuroimaging researc... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - May 4, 2019 Category: Psychiatry Authors: Christopher C. Abbott, Jeremy Miller, Megan Lloyd and Mauricio Tohen Tags: Review Source Type: research

Metabolic profile in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives
The prevalence of metabolic syndrome and insulin resistance is twice as high in patients with bipolar disorder compared with the general population, and possibly associated with a disabling illness trajectory ... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - April 2, 2019 Category: Psychiatry Authors: Klara Coello, Maj Vinberg, Filip K. Knop, Bente K. Pedersen, Roger S. McIntyre, Lars V. Kessing and Klaus Munkholm Tags: Research Source Type: research

Intra-individual variability in animal models of bipolar disorder
(Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - April 2, 2019 Category: Psychiatry Authors: Emily R. Hawken, Elisa Brietzke and Claudio N. Soares Tags: Letter to the Editor Source Type: research

Controversies in bipolar disorder; role of second-generation antipsychotic for maintenance therapy
In this narrative review, we discuss use of second-generation antipsychotics (SGAs) in maintenance treatment of bipolar disorder. We compare their use to historically more established treatments (particularly ... (Source: International Journal of Bipolar Disorders)
Source: International Journal of Bipolar Disorders - March 27, 2019 Category: Psychiatry Authors: Sameer Jauhar and Allan H. Young Tags: Review Source Type: research