[Online-based, qualified second opinion for patients with colorectal cancer - A pilot study of the Felix Burda Foundation in co-operation with the Network against Colorectal Cancer].
CONCLUSION:  Generating an online-based, qualified second opinion by an interdisciplinary tumour board is technically and logistically well feasible. The online-based second opinion could significantly improve the quality of treatment for patients with colorectal cancer in the future and thus improve their quality of life. PMID: 32450585 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - May 25, 2020 Category: Gastroenterology Authors: Berger U, Beckenbauer UE, Rimkus C, Bader FG, Seufferlein TTW, Maar C Tags: Z Gastroenterol Source Type: research

[Full thickness resection of a pyloric adenoma in the proximal duodenum in a 67-year-old patient with attenuated polyposis coli].
CONCLUSION:  Herein we present the first case of duodenal EFTR in a patient with attenuated FAP and a PGA. There are currently no specific guidelines for the removal and surveillance. ASGE recommends resection and surveillance endoscopy at 3-5 years interval. PMID: 32380553 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - May 7, 2020 Category: Gastroenterology Authors: Anliker O, Sieweke W, Töpfer A, Wülker I, Breidert M Tags: Z Gastroenterol Source Type: research

[Removal of an Uncovered Metal Stent from the Common Bile Duct Six  Years after Implantation in Chronic Calcifying Pancreatitis].
We report a patient with chronic calcifying pancreatitis and cholestasis who, after unsuccessful multistenting with a total of 15 stent changes, was implanted with an uncoated metal stent in the common bile duct as second-line therapy. After this stent had been in place for six years and had to be balloon-cleaned 19 times during this time, the indication for removal came up. A fully coated metal stent of the same diameter but 2 cm longer was inserted into the lumen of the uncoated stent. It was left in place for 9 months and cleaned once during this time. Then, via ERCP, both stents were extended in a telescope-like ma...
Source: Zeitschrift fur Gastroenterologie - May 7, 2020 Category: Gastroenterology Authors: Hentschel F, Lüth S Tags: Z Gastroenterol Source Type: research

Rare heterochronous liver and pancreatic multiple primary cancers: a case report and literature review.
We report this case to raise the clinician's attention to the disease because the long-term survival rate can be effectively improved by timely diagnosis and appropriate treatment. For patients with HCV-positive primary cancers, active antiviral therapy should be simultaneously provided with antitumor therapy, thereby effectively reducing the incidence of MPC. PMID: 32380555 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - May 7, 2020 Category: Gastroenterology Authors: Zhang W, Xiao F, Li J, Guo X, Lin Z, Huang Z, Mao N, Sun B, Wang G Tags: Z Gastroenterol Source Type: research

Bouveret's Syndrome - Case Series with Therapeutic Implications.
Abstract Bouveret's syndrome is a rare complication resulting from gallstone disease. Both surgical and endoscopical procedures are performed, with the disease to be seen as strictly interdisciplinary. There are no well-established recommendations for this condition. In this paper, we want to describe our experience from 6 cases in 3 Swiss hospitals from 2015 to 2017 with emphasis on the endoscopic technique of electrohydraulic lithotripsy followed by balloon dilatation and propose a treatment algorithm. PMID: 32353887 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - April 1, 2020 Category: Gastroenterology Authors: Kukiolka T, Borovicka J, Baumeler S, Schiesser M, Gubler C Tags: Z Gastroenterol Source Type: research

[3 unusual courses of gastrointestinal MALT lymphoma].
We report on the unusual course of disease in three patients with gastrointestinal MALT lymphoma. Special features are the primary lymphoma manifestation, the high-grade transformation during the follow up, the long-time interval between initially curative intended therapy and relapse and the occurrence of another neoplasia in one case. This demonstrates that despite their good prognosis in general, follow-up investigations of gastrointestinal MALT lymphoma are reasonable. PMID: 32353888 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - April 1, 2020 Category: Gastroenterology Authors: Fischbach W, Eck M, Dorlöchter C Tags: Z Gastroenterol Source Type: research

[Inderdisciplinary care of patients with short-bowel-syndrome in  Germany: A comparative Cost-of-Illness analysis of in- and outpatient care].
CONCLUSIONS:  The interdisciplinary medical care of SBS-patients is resource-intensive and expensive. The required treatment shifts from the in- to the outpatient sector. Both settings are at present not adequately reimbursed. Hence, this imbalance may endanger adequate care for SBS-patients in the future in times of economic rationale. In concordance with other rare disease management programs, additional measures are needed to provide and improve interdisciplinary treatment of SBS. PMID: 32353889 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - April 1, 2020 Category: Gastroenterology Authors: Muazzam MN, Hauk C, Arensmeyer J, Hausen A, Koeppen P, Kalff JC, von Websky MW Tags: Z Gastroenterol Source Type: research

[Successful intraductal radiofrequency ablation of residual adenoma tissue following endoscopic papillectomy].
We report about two patients with papillary adenoma who had residual adenoma in the center of the ductus hepatocholedochus papillary region after endoscopic papillectomy. Due to missing possibility of further endoscopic resection we carried out endobiliary radiofrequency ablation instead of surgical treatment. In follow-up examination, there where no macroscopic or histological relapse, therefore endobiliary radiofrequency ablation needs to be discussed as an alternative to surgical therapy option. PMID: 32198738 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - March 1, 2020 Category: Gastroenterology Authors: Gereitzig N, Ziegan RA, Tischendorf JJW Tags: Z Gastroenterol Source Type: research

[Paradigm shift in understanding Acute kidney injury in patients with  chronic liver disease: From pathophysiology to defining disease entities].
[Paradigm shift in understanding Acute kidney injury in patients with chronic liver disease: From pathophysiology to defining disease entities]. Z Gastroenterol. 2020 Mar;58(3):254-266 Authors: Scurt FG, Bose K, Canbay A, Mertens PR, Chatzikyrkou C Abstract The hepatorenal syndrome (HRS) is only a part of the wide spectrum of renal injury in patients with end-stage liver cirrhosis. Besides that, the advanced liver disease itself, or its underlying causes, as well as comorbidities, like diabetes mellitus, adiposity and arterial hypertension, can directly cause parenchymal renal insults (bile ...
Source: Zeitschrift fur Gastroenterologie - March 1, 2020 Category: Gastroenterology Authors: Scurt FG, Bose K, Canbay A, Mertens PR, Chatzikyrkou C Tags: Z Gastroenterol Source Type: research

An den Editor – 16.01.2020.
An den Editor – 16.01.2020. Z Gastroenterol. 2020 Mar;58(3):267 Authors: PMID: 32198740 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - March 1, 2020 Category: Gastroenterology Tags: Z Gastroenterol Source Type: research

[Erlotinib plus Gemcitabine in metastatic pancreatic cancer: Results  from a non-interventional trial].
In conclusion, these results from the daily treatment routine of metastatic pancreatic cancer underline the importance of combined gemcitabine/erlotinib therapy for a subgroup of patients who develop a rash in the course of erlotinib treatment. PMID: 32052394 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - February 12, 2020 Category: Gastroenterology Authors: Westphalen CB, Heinemann V, Tessen HW, Groschek M, Hoeffkes HG, Marschner N, Schulze M, Beringer A, Waldschmidt D Tags: Z Gastroenterol Source Type: research

Ustekinumab serum concentrations are associated with clinical outcomes in Crohn's disease - a regional multi-center pilot study.
CONCLUSION:  Trough concentrations of UST 8 weeks after induction predict clinical response to therapy in week 16 with moderate sensitivity and specificity. TDM using LC-MSMS could prove beneficial in personalized UST therapy of patients with CD by identifying individuals with subtherapeutic concentrations who might benefit from dose escalation. PMID: 32045954 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - February 11, 2020 Category: Gastroenterology Authors: Thomann AK, Schulte LA, Globig AM, Hoffmann P, Klag T, Itzel T, Teufel A, Schreiner R, Scheffe N, Ebert MP, Wehkamp J, Gauss A, Hasselblatt P, Klaus J, Reindl W Tags: Z Gastroenterol Source Type: research

[Current standard of antibiotic prophylaxis in esophageal varices bleeding in Germany].
CONCLUSION:  Our study shows that the applied standards for antibiotic prophylaxis in esophageal varices bleeding varies greatly in Germany. Future studies about the necessary duration of prophylaxis and its dependency from the Child-Pugh-Score are needed so that unnecessary antibiotic prescriptions can be avoided. The avoidance of antibiotic prophylaxis in elective banding of non-bleeding esophageal varices, which is not recommended by guidelines and was used by about 20 % of participants in our study, can already reduce antibiotic use. PMID: 32045955 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - February 11, 2020 Category: Gastroenterology Authors: Zhelegu I, Ebert MP, Vogelmann R Tags: Z Gastroenterol Source Type: research

Treatment-failure to direct antiviral HCV regimens in real world: frequency, patient characteristics and rescue therapy - data from the  German hepatitis C registry (DHC-R).
Treatment-failure to direct antiviral HCV regimens in real world: frequency, patient characteristics and rescue therapy - data from the German hepatitis C registry (DHC-R). Z Gastroenterol. 2020 Feb 10;: Authors: Schmitt A, Günther R, Mauss S, Boeker KHW, Buggisch P, Hillenbrand H, John C, Klinker H, Pathil A, Simon KG, Serfert Y, Niederau C, Vermehren J, Wedemeyer H, Sarrazin C Abstract BACKGROUND:  Virologic failure to approved combinations of direct antiviral agents (DAA) in patients with chronic hepatitis C virus (HCV) infection is rare. Mostly it involves difficult to treat patient...
Source: Zeitschrift fur Gastroenterologie - February 10, 2020 Category: Gastroenterology Authors: Schmitt A, Günther R, Mauss S, Boeker KHW, Buggisch P, Hillenbrand H, John C, Klinker H, Pathil A, Simon KG, Serfert Y, Niederau C, Vermehren J, Wedemeyer H, Sarrazin C Tags: Z Gastroenterol Source Type: research

Infodemiology of Crohn's disease and Ulcerative colitis using Google  Trends - an approach to investigate patient needs.
CONCLUSION:  This study showed a need of information concerning symptoms, nutrition and therapy that should be considered during patient education. Since time in physician patient dialogue is short it may be helpful to further evaluate websites independently in order to give recommendations of websites offering reliable information. PMID: 32018314 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - February 4, 2020 Category: Gastroenterology Authors: Keller R, Fusco S, Stange EF, Malek NP, Wehkamp J, Klag T Tags: Z Gastroenterol Source Type: research

Current status of immunotherapy in gastrointestinal malignancies.
This article will address the current use and evidence for immunotherapy in GI malignancies and future trends in this area for clinical practice. PMID: 32018315 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - February 4, 2020 Category: Gastroenterology Authors: Lorenzen S, Lordick F, Loosen SH, Tacke F, Trautwein C, Roderburg C, Ettrich TJ, Perkhofer L, Reinacher-Schick A, Stein A Tags: Z Gastroenterol Source Type: research

Risk factors for bleeding from gastrointestinal angiodysplasia: a  case-control study in patients with bleeding and non-bleeding angiodysplasia.
CONCLUSIONS:  The amount of AD is clearly correlated to the age of the patient. A higher number of ADs and inhibition of primary hemostasis increase the risk of bleeding. PMID: 32018316 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - February 4, 2020 Category: Gastroenterology Authors: Neu B, Moessmer G, Bajbouj M, Becker V, Barthel P, Seidl H, Schepp W, Anzinger M, Dollhopf M, Meining A, Schmid RM, Budde U, Noe S Tags: Z Gastroenterol Source Type: research

Urgent endoscopy in patients with "true foreign bodies" in  the upper gastrointestinal tract - a retrospective study of the period 1994-2018.
CONCLUSIONS:  Urgent endoscopy has proved successful in removing true foreign bodies from the upper gastrointestinal tract in the analyzed period. Different factors affect the success of urgent intervention, the most important being adequate experience, skills, and patience of the endoscopic team. PMID: 32018317 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - February 4, 2020 Category: Gastroenterology Authors: Skok P, Skok K Tags: Z Gastroenterol Source Type: research

[What the (abdominal) surgeon needs to know on novel insights regarding cholic acids and their interaction with the intestinal microbioma].
CONCLUSION:  CA are a parade example for metabolic regulators, the interactions of which have an impact onto various (patho-)biochemical and (-)physiological processes, (abdomino-)surgically relevant diseases and (abdomino-)surgical measures. Their biochemical/physiological activities and insight into associated molecular processes should be part of the medical and scientific skills of a modern (abdominal) surgeon with a developed pathophysiological expertise. PMID: 32018318 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - February 4, 2020 Category: Gastroenterology Authors: Schönfeld P, Meyer F Tags: Z Gastroenterol Source Type: research

EpiCO (epirubicin, cyclophosphamide and vincristine) as treatment for extrapulmonary high-grade neuroendocrine neoplasms.
In this report we present the retrospective series of 5 cases with metastatic high-grade GEP/CUP NEN/MiNEN who received chemotherapy according to this protocol. PMID: 31896137 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - January 2, 2020 Category: Gastroenterology Authors: Munker S, Vogelhuber M, Bornschein J, Stroszczynski C, Evert M, Schlitt H, Herr W, Teufel A Tags: Z Gastroenterol Source Type: research

[Prognostic significance and economic burden of hepatic encephalopathy in liver cirrhosis in German hospitals based on G-DRG data].
DISCUSSION:  Mortality is threefold increased in patients with cirrhosis when an additional HE is diagnosed. Hospitals participating in the DGVS-DRG-project coded 2 % more HE cases among their cirrhosis cases than the rest of hospitals either because of a selection bias for greater disease severity or because of better coding quality. At present, reimbursement for HE patients on the basis of F-DRG-system produced a deficit. PMID: 31863425 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - December 20, 2019 Category: Gastroenterology Authors: Gundling F, Rathmayer M, Koller L, Wilke M, Kircheis G, Wedemeyer H, Labenz J, Albert J, Schepp W, Lerch MM, für die DRG-Projektgruppe der DGVS Tags: Z Gastroenterol Source Type: research

[The endoscopic approach to indeterminate biliary stricture: current  practice and future perspective].
[The endoscopic approach to indeterminate biliary stricture: current practice and future perspective]. Z Gastroenterol. 2019 Dec 20;: Authors: Walter D, Albert J, Jung M, Friedrich-Rust M Abstract Patients with indeterminate biliary stricture frequently pose a challenge in the clinical management. Patients with malignant and potentially resectable diseases should be treated surgically as soon as possible. On the other hand, in patients with benign diseases which might be cured with medial treatment, surgery should be avoided. This review shall provide a concise overview on the diagnostic yield of...
Source: Zeitschrift fur Gastroenterologie - December 20, 2019 Category: Gastroenterology Authors: Walter D, Albert J, Jung M, Friedrich-Rust M Tags: Z Gastroenterol Source Type: research

Vielen Dank!
Authors: PMID: 31826276 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - December 1, 2019 Category: Gastroenterology Tags: Z Gastroenterol Source Type: research

[Structure of the gastroenterologic departments/clinics in Germany - a survey by the working group of the guiding gastroenterologic clinicians (ALGK)].
PMID: 31826277 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - December 1, 2019 Category: Gastroenterology Authors: Frieling T, Behrens A, Labenz J, Leifeld L, Madisch A, Schilling D, Terjung B, Wieland E Tags: Z Gastroenterol Source Type: research

A study on the correlation of gastrointestinal bleeding and meteorological factors - is there a weather condition for GI bleeding?
CONCLUSIONS:  Our study does not support the correlation of meteorological conditions with the frequency of GIB per se. However, we found a statistically significant increase of variceal bleeding episodes along with lower ambient temperatures and pronounced changes in daily temperature. Patients at risk for variceal hemorrhage should be advised to avoid exposure to low temperatures, whenever possible. Ulcerative bleeding was significantly associated with changes in air pressure. PMID: 31826278 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - December 1, 2019 Category: Gastroenterology Authors: Prechter F, Bürger M, Lehmann T, Stallmach A, Schmidt C Tags: Z Gastroenterol Source Type: research

Long-term outcomes of per-oral endoscopic myotomy in a patient with distal esophageal spasm followed up for 2.5 years: two sides of  the same coin - A Case Report and Literature Review.
CONCLUSIONS:  We herein report a case of DES who underwent POEM to eliminate persistent esophageal contractions. Eckardt score, esophageal emptying test, and high-resolution manometry were assumed to monitor the efficacy of POEM. During treatment and 2.5 years after operation, esophageal muscle biopsies and/or mucosal tissues were obtained. This case has been presented to describe that POEM could be a strategy for DES with a long-term curative effect and that eosinophils in the muscle layer of the esophagus might be involved in the pathogenesis of DES. What is more, we reviewed literature to find similar cases repor...
Source: Zeitschrift fur Gastroenterologie - December 1, 2019 Category: Gastroenterology Authors: Wang B, Jin H, Zhao W, Zhao C, Wang T, Zhang L, Sun F, Wang B, Song J Tags: Z Gastroenterol Source Type: research

[Disseminated tuberculosis mimicking metastatic gastric cancer - a  case report].
We report the case of a 77-year-old male patient who presented with unilateral leg pain and B symptoms. Further investigations revealed an osteolytic mass in the sacrum as well as CT-morphological findings consistent with metastatic gastric cancer. However, transgastric biopsies showed necrotising granuloma with giant cells leading to molecular and cultural detection of Mycobacterium tuberculosis instead of suspected neoplastic tissue. A nine-month treatment regimen for suspected disseminated tuberculosis with bone involvement was initiated according to national guidelines. Clinical and radiological follow up examinations ...
Source: Zeitschrift fur Gastroenterologie - December 1, 2019 Category: Gastroenterology Authors: Voit FM, Abdelhafez M, Rothe K, Slotta-Huspenina J, Gaa J, Schmid RM, Spinner CD Tags: Z Gastroenterol Source Type: research

[Neuroendocrine tumors in daily gastroenterology and endoscopy - a  practice manual].
This article gives an overview regarding the key aspects of GI-NET therapy in daily gastroenterology practice with emphasis on endoscopic diagnosis and therapy. PMID: 31826281 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - December 1, 2019 Category: Gastroenterology Authors: Spindelböck W, Kump PK, Püspök A, Koch R, Mayerhöfer M, Haug A, Fritz E, Obermayer-Pietsch B, Raderer M, Tribl B Tags: Z Gastroenterol Source Type: research

[Appendicectomy prior to colectomy in ulcerative colitis?]
PMID: 31826282 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - December 1, 2019 Category: Gastroenterology Authors: Helwig U Tags: Z Gastroenterol Source Type: research

Aktualisierte S3-Leitlinie des Magenkarzinoms nun ver öffentlicht.
Aktualisierte S3-Leitlinie des Magenkarzinoms nun veröffentlicht. Z Gastroenterol. 2019 Dec;57(12):1515-1516 Authors: Möhler M PMID: 31826283 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - December 1, 2019 Category: Gastroenterology Authors: Möhler M Tags: Z Gastroenterol Source Type: research

S3-Leitlinie Magenkarzinom – Diagnostik und Therapie der Adenokarzinome des Magens und des ösophagogastralen Übergangs – Langversion 2.0 – August 2019. AWMF-Registernummer: 032/009OL.
S3-Leitlinie Magenkarzinom – Diagnostik und Therapie der Adenokarzinome des Magens und des ösophagogastralen Übergangs – Langversion 2.0 – August 2019. AWMF-Registernummer: 032/009OL. Z Gastroenterol. 2019 Dec;57(12):1517-1632 Authors: Moehler M, Al-Batran SE, Andus T, Arends J, Arnold D, Baretton G, Bornschein J, Budach W, Daum S, Dietrich C, Ebert M, Fischbach W, Flentje M, Gockel I, Grenacher L, Haier J, Höcht S, Jakobs R, Jenssen C, Kade B, Kanzler S, Langhorst J, Link H, Lordick F, Lorenz D, Lorenzen S, Lutz M, Messmann H, Meyer HJ, Mönig S, Ott K, Quante M, Röck...
Source: Zeitschrift fur Gastroenterologie - December 1, 2019 Category: Gastroenterology Authors: Moehler M, Al-Batran SE, Andus T, Arends J, Arnold D, Baretton G, Bornschein J, Budach W, Daum S, Dietrich C, Ebert M, Fischbach W, Flentje M, Gockel I, Grenacher L, Haier J, Höcht S, Jakobs R, Jenssen C, Kade B, Kanzler S, Langhorst J, Link H, Lordick F Tags: Z Gastroenterol Source Type: research

Leitlinienreport der aktualisierten S3-Leitlinie Colitis ulcerosa der Deutschen Gesellschaft f ür Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS).
Leitlinienreport der aktualisierten S3-Leitlinie Colitis ulcerosa der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS). Z Gastroenterol. 2019 Nov;57(11):e397-e402 Authors: van Leeuwen P, Dignass A, Kucharzik T, Jansen PL PMID: 31739371 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - November 1, 2019 Category: Gastroenterology Authors: van Leeuwen P, Dignass A, Kucharzik T, Jansen PL Tags: Z Gastroenterol Source Type: research

Aktualisierung der S3-Leitlinie Colitis ulcerosa 2019.
nd B PMID: 31739372 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - November 1, 2019 Category: Gastroenterology Authors: Kucharzik T, Dignaß A, Siegmund B Tags: Z Gastroenterol Source Type: research

Frequency and clinical presentation of alveolar and cystic echinococcosis in a tertiary medical center in Germany 2004-2018: lessons from a low-prevalence area.
CONCLUSIONS:  AE and CE are rare diseases in the greater Leipzig region; however, case numbers are on the rise. Due to favorable factors such as the escalation of migration, a further increase is expected. Diagnosis and therapy are challenging and should be supported by specialists (experienced infectiologists, imaging experts and skilled hepatobiliary surgeons) who should be integrated in a German network. PMID: 31739373 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - November 1, 2019 Category: Gastroenterology Authors: Karlas T, Reinhardt F, Blank V, Lippmann N, Seehofer D, Lübbert C Tags: Z Gastroenterol Source Type: research

[Acceptance of fecal microbiota transfer among patients with chronic  inflammatory bowel diseases in a highly specialized outpatient department: a questionnaire-based survey].
[Acceptance of fecal microbiota transfer among patients with chronic inflammatory bowel diseases in a highly specialized outpatient department: a questionnaire-based survey]. Z Gastroenterol. 2019 Nov;57(11):1291-1297 Authors: Schulte LA, Schäfer A, Steding K, Rauschek L, Klaus J Abstract Recently, research in the treatment of inflammatory bowel diseases has become increasingly focused on fecal microbiota transfer (FMT) due to increasing evidence of its possible benefits. Still, there are doubts about this method, because there is contradicting evidence regarding its effectiveness and the po...
Source: Zeitschrift fur Gastroenterologie - November 1, 2019 Category: Gastroenterology Authors: Schulte LA, Schäfer A, Steding K, Rauschek L, Klaus J Tags: Z Gastroenterol Source Type: research

Immunoglobulin G4 (IgG4)-related disease of the stomach - a  challenging differential diagnosis in suspected gastric cancer.
CONCLUSION:  IgG4-RD should be taken into account when gastric malignancy is suspected endoscopically or radiologically and biopsies fail to confirm the presence of a malignancy (especially subepithelial tumors or refractory gastric ulcers). Serum IgG4 concentrations are insufficient to confirm localized gastric IgG4-RD. Diagnostic workups need to be improved to avoid unnecessary surgical resections with the attendant potential morbidity and mortality. PMID: 31739375 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - November 1, 2019 Category: Gastroenterology Authors: Probst A, Schaller T, Sommer F, Geissler B, Agaimy A, Messmann H, Märkl B Tags: Z Gastroenterol Source Type: research

Chronic gastric ulcer disease complicating selective internal radiation therapy (SIRT) in a patient with cholangiocellular carcinoma.
k J Abstract Selective internal radiation therapy (SIRT) is a therapeutic option for primary and metastatic liver tumors. Microspheres containing Yttrium 90, a beta-emitting radionuclide, are administered into the hepatic artery allowing selective internal radiation of a liver tumor. SIRT-related complications may appear due to migration of the radiation microspheres to organs distant from the tumor site. In order to prevent these complications, unintended non target embolization of Yttrium microspheres has to be avoided. However, data from external-beam radiation therapy (EBRT) suggests that the stomach/small bow...
Source: Zeitschrift fur Gastroenterologie - November 1, 2019 Category: Gastroenterology Authors: Blesl A, Brcic I, Jaschke W, Öfner D, Fickert P, Plank J Tags: Z Gastroenterol Source Type: research

[Current recommendations for surveillance, risk reduction and therapy in Lynch syndrome patients].
CONCLUSION:  LS colonic and extracolonic clinical management, surveillance and therapy are complex and several aspects remain unclear. In the future, surveillance and clinical management need to be more tailored to gene and gender. Future prospective trials are needed. PMID: 31739377 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - November 1, 2019 Category: Gastroenterology Authors: Hüneburg R, Aretz S, Büttner R, Daum S, Engel C, Fechner G, Habermann JK, Heling D, Hoffmann K, Holinski-Feder E, Kloor M, von Knebel-Döberitz M, Loeffler M, Möslein G, Perne C, Redler S, Rieß O, Schmiegel W, Seufferlein T, Siebers-Renelt U, Steinke- Tags: Z Gastroenterol Source Type: research

[August 2019 - AWMF-Registriernummer: 021-009].
orators: PMID: 31739378 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - November 1, 2019 Category: Gastroenterology Authors: Kucharzik T, Dignass AU, Atreya R, Bokemeyer B, Esters P, Herrlinger K, Kannengießer K, Kienle P, Langhorst J, Lügering A, Schreiber S, Stallmach A, Stein J, Sturm A, Teich N, Siegmund B, Collaborators: Tags: Z Gastroenterol Source Type: research

An insight into Clostridium difficile infection: a single-center retrospective case-control study.
CONCLUSION:  A timely use of NLR can be used as a mean to predict worse outcomes, namely ICU transfer and mortality, in patients with CDI. PMID: 31610581 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - October 1, 2019 Category: Gastroenterology Authors: Haddad FG, Zaidan J, Polavarapu A, Khan H, Khan A, Mudduluru BM, Saabiye J, Lukanovic S, Demissie S, Mulrooney S, Khalil A Tags: Z Gastroenterol Source Type: research

Percutaneous transhepatic cholangioscopic lithotripsy using soft fiber-optic choledochoscope.
Abstract Many patients with intrahepatic cholelithiasis need surgical treatment during their life. For patients with hepatolithiasis, conventional therapy methods suggest partial hepatectomy or hepatic transplantation, while both kinds of surgery carry a considerable risk and trauma. Under such conditions, percutaneous transhepatic cholangioscopic lithotripsy provides an alternative method for hepatolithiasis treatment. Conventional rigid choledochoscope applied in percutaneous transhepatic cholangioscopic lithotripsy often lack sufficient flexibility for complete intrahepatic bile duct inspection. In this article...
Source: Zeitschrift fur Gastroenterologie - October 1, 2019 Category: Gastroenterology Authors: Jin H, Fan J, Li W, Cui M Tags: Z Gastroenterol Source Type: research

[Smoldering diverticultis - still a type of chronic recurrent diverticulitis with good indication for surgery? - Surgery for smoldering diverticulitis].
CONCLUSION:  In patients with SmD like chronic recurrent disease surgery is effective to improve quality of life. PMID: 31610583 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - October 1, 2019 Category: Gastroenterology Authors: Rink AD, Nousinanou ME, Hahn J, Dikermann M, Paul C, Vestweber KH Tags: Z Gastroenterol Source Type: research

A 2-step fast-track elastometry service for advanced workup of nonalcoholic fatty liver disease (NAFLD) patients - single-center real-world experience of outpatient clinical practice.
CONCLUSION:  Questionnaire-based referral from primary care followed by broadly available fast-track TE and eventually liver biopsy for selected patients is the standard practice in our unit. This approach represents a feasible model to handle the large gap between availability and clinical need for TE facilities. PMID: 31610584 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - October 1, 2019 Category: Gastroenterology Authors: Alsenbesy M, Rau M, Weiss J, Götze O, Geier A Tags: Z Gastroenterol Source Type: research

Genetic prediction profile for adalimumab response in Slovenian Crohn's disease patients.
DISCUSSION:  Our study supports the reported genetic anti-TNF response profile and extends it for adalimumab prediction. PMID: 31610585 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - October 1, 2019 Category: Gastroenterology Authors: Gorenjak M, Repnik K, Jezernik G, Jurgec S, Skok P, Potočnik U Tags: Z Gastroenterol Source Type: research

[Endoscopic resection of a scarred rectal adenoma using EndoRotor].
CONCLUSION:  Scarred adenomas pose a challenge for interventional endoscopy. In this case study, EndoRotor proved to be a safe and viable method and a new resection option for complicated scarred rectal adenomas. PMID: 31610586 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - October 1, 2019 Category: Gastroenterology Authors: Stadler A, Knabe M, May A Tags: Z Gastroenterol Source Type: research

[Positive fecal immunochemical test in asymptomatic individuals and despite of recent colonoscopy - Calm down or repeat colonoscopy?]
PMID: 31610587 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - October 1, 2019 Category: Gastroenterology Authors: Lenze F, Bokemeyer A Tags: Z Gastroenterol Source Type: research

Prof. Dr. med. Stefan Zeuzem.
PMID: 31525796 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - September 1, 2019 Category: Gastroenterology Authors: Siegmund B Tags: Z Gastroenterol Source Type: research

The effect of gender-specific invitation letters on utilization of  colorectal cancer screening.
CONCLUSIONS:  Gender-specific design of invitation letters can modify the patients' preference for specific CRC screening services and increase the acceptance of screening colonoscopy. PMID: 31525797 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - September 1, 2019 Category: Gastroenterology Authors: Zhan T, Hielscher T, Eckardt M, Giese T, Schäfer C, Riemann JF, Ebert MP, Belle S Tags: Z Gastroenterol Source Type: research

Physicians' view on sigmoidoscopy as an additionally offered method for colorectal cancer screening.
CONCLUSIONS:  The survey provides important practical insights into outpatient sigmoidoscopy. A majority of the physicians does not support evidence-based sigmoidoscopy for CRC screening. However, individuals who reject a colonoscopy are, in line with the current guideline, identified as a target group for a screening sigmoidoscopy. The benefit from an additionally offered sigmoidoscopy in CRC screening should be further analyzed with special consideration given to the preferences of insurees within the German healthcare system. PMID: 31525798 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - September 1, 2019 Category: Gastroenterology Authors: Cespedes I, Seidler U, Walter U, Dreier M Tags: Z Gastroenterol Source Type: research

[Challenges in diagnostics for intestinal tuberculosis - Pitfalls of  a forgotten infectious disease: case series and literature review].
[Challenges in diagnostics for intestinal tuberculosis - Pitfalls of a forgotten infectious disease: case series and literature review]. Z Gastroenterol. 2019 Sep;57(9):1067-1076 Authors: Ammer-Herrmenau C, Henrici P, Eiffert H, Amanzada A, Mechie NC, Bremmer F, Seif Amir Hosseini A, Ellenrieder V, Wedi E Abstract Intestinal tuberculosis is an infectious disease of the extrapulmonary manifestation with the Mycobacteria tuberculosis complex. In developed countries, this disease is rarely seen. The clinical features are heterogeneous and unspecific. Furthermore, intestinal tuberculosis poses d...
Source: Zeitschrift fur Gastroenterologie - September 1, 2019 Category: Gastroenterology Authors: Ammer-Herrmenau C, Henrici P, Eiffert H, Amanzada A, Mechie NC, Bremmer F, Seif Amir Hosseini A, Ellenrieder V, Wedi E Tags: Z Gastroenterol Source Type: research