1983-2023 - Four decades Helicobacter pylori - what's next?
Z Gastroenterol. 2024 Jan 18. doi: 10.1055/a-2207-7185. Online ahead of print.ABSTRACTFour decades ago the discovery of Helicobacter pylori was first reported in the international medical literature. Since then, there have been significant developments in basic and clinical science that have been translated into daily clinical practice. Changes in the management of H. pylori infection have occurred in diagnostic algorithms, indications for therapy and therapy itself. A special focus is directed to strategies of gastric cancer prevention.This manuscript briefly reviews the milestone in 40 years of H. pylori management.PMID:...
Source: Zeitschrift fur Gastroenterologie - January 18, 2024 Category: Gastroenterology Authors: Christian Schulz Kerstin Sch ütte Alexander Link Peter Malfertheiner Source Type: research
1983-2023 - Four decades Helicobacter pylori - what's next?
Z Gastroenterol. 2024 Jan 18. doi: 10.1055/a-2207-7185. Online ahead of print.ABSTRACTFour decades ago the discovery of Helicobacter pylori was first reported in the international medical literature. Since then, there have been significant developments in basic and clinical science that have been translated into daily clinical practice. Changes in the management of H. pylori infection have occurred in diagnostic algorithms, indications for therapy and therapy itself. A special focus is directed to strategies of gastric cancer prevention.This manuscript briefly reviews the milestone in 40 years of H. pylori management.PMID:...
Source: Zeitschrift fur Gastroenterologie - January 18, 2024 Category: Gastroenterology Authors: Christian Schulz Kerstin Sch ütte Alexander Link Peter Malfertheiner Source Type: research
1983-2023 - Four decades Helicobacter pylori - what's next?
Z Gastroenterol. 2024 Jan 18. doi: 10.1055/a-2207-7185. Online ahead of print.ABSTRACTFour decades ago the discovery of Helicobacter pylori was first reported in the international medical literature. Since then, there have been significant developments in basic and clinical science that have been translated into daily clinical practice. Changes in the management of H. pylori infection have occurred in diagnostic algorithms, indications for therapy and therapy itself. A special focus is directed to strategies of gastric cancer prevention.This manuscript briefly reviews the milestone in 40 years of H. pylori management.PMID:...
Source: Zeitschrift fur Gastroenterologie - January 18, 2024 Category: Gastroenterology Authors: Christian Schulz Kerstin Sch ütte Alexander Link Peter Malfertheiner Source Type: research
Pituitary metastasis arising from hepatocellular carcinoma: a case report and update of the literature
Z Gastroenterol. 2024 Jan 15. doi: 10.1055/a-2225-5057. Online ahead of print.ABSTRACTHepatocellular carcinoma (HCC) is the sixth most common neoplasia and the third leading cause of cancer-associated deaths worldwide. Most cases arise in patients with cirrhosis, and early detection through periodic screening can make it potentially curable. The presence of extrahepatic metastases (EHM) affects treatment decisions and curability. The lungs are the most common site for EHM, followed by lymph nodes, bones, and the adrenal glands. Interestingly, approximately only 15 cases of HCC metastasizing to the pituitary gland have been...
Source: Zeitschrift fur Gastroenterologie - January 15, 2024 Category: Gastroenterology Authors: Isaac Rodriguez Lena Vogel Constantin Dreher Asan Cherkezov Frank Giordano Matthias Fr ölich Matthias Philip Ebert Andreas Teufel Judit Boda-Heggemann Source Type: research
Zum Einsatz von PMA - Zeolith (Klinoptilolith) bei Patienten mit Reizdarmsyndrom - eine nicht-interventionelle Studie
Z Gastroenterol. 2024 Jan 15. doi: 10.1055/a-2223-3963. Online ahead of print.ABSTRACTDie medizinische Betreuung von Patienten mit Reizdarmsyndrom (RDS) kann sehr herausfordernd sein. Die Ziele der vorliegenden Nicht-Interventionellen-Studie (NIS) waren die Dokumentation der Verträglichkeit und Wirksamkeit des PMA-Zeoliths unter Alltagsbedingungen bei Patienten mit durchfallartigem RDS-Typ (RDS-D) oder Obstipationstyp (RDS-C) oder Mischtyp (RDS-M).METHODEN: Im Rahmen einer bundesweiten NIS wurden 204 Patienten mit RDS rekrutiert, um Daten zu Verträglichkeit, Lebensqualität, und Symptomfrequenz zu gewinnen. Die Studie ko...
Source: Zeitschrift fur Gastroenterologie - January 15, 2024 Category: Gastroenterology Authors: Wilhelm Mosgoeller Claus Muss Sandra Eisenwagen Reinhold Jagsch Harald Vogelsang Source Type: research
Elevated liver enzymes in a German tertiary-care hospital: Distribution, diagnostic steps and diagnosis groups
CONCLUSION: Clinicians are often faced with elevated liver enzymes. However, diagnostic steps differ between different specialties. Physicians should be aware of the increased in-hospital mortality in cases with hyperbilirubinemia or elevated AST/ALT ratios.PMID:38198801 | DOI:10.1055/a-2150-2077 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - January 10, 2024 Category: Gastroenterology Authors: Kilian Bock Heiner Wedemeyer Young-Seon Mederacke Ingmar Mederacke Source Type: research
Endoscopic ultrasound for structured surveillance after curative treatment of esophageal cancer
CONCLUSION: Structured surveillance offers the chance to identify limited and asymptomatic tumor relapse. Especially in cases of locoregional recurrence, long-lasting survival or even a cure can be achieved. Endoscopic ultrasound is the best method for the detection of locoregional tumor recurrence and should be an integral part of structured surveillance after curative treatment of esophageal cancer.PMID:38198802 | DOI:10.1055/a-2125-6923 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - January 10, 2024 Category: Gastroenterology Authors: Wolfram Bohle Lioba Nowack Andre Schaudt Joerg Koeninger Wolfram G Zoller J örg G Albert Source Type: research
Transanal Endoscopic Microsurgery (TEM) is a surgical option to preserve fecal continence in selected low rectal cancers
We examined the results using V-TEM with reduced acquisition costs in the resection of adenomas and carcinomas and discussed its importance by literature .METHOD: From 2003 to 2019, 154 patients with 170 findings were operated by V-TEM technology. Data on the operation and follow-up were collected and analyzed retrospectively.RESULTS: The median age was 67 years, 89 patients were male and 65 female. V-TEM was performed on 79 carcinomas, 77 adenomas and 14 other findings. The complication rate was 21.2 %. R0 resection was achieved in 78.8 %. The adenoma recurrence rate was 7.3 %, the overall recurrence rate for carcinomas 1...
Source: Zeitschrift fur Gastroenterologie - January 10, 2024 Category: Gastroenterology Authors: Katrin Marlene Schaffitzel Stephanie Zu Putlitz Stefan Karl G ölder Ralf Kurek Marco Siech Source Type: research
S3-Leitlinie „Diagnostik und Therapie des Hepatozellulären Karzinoms“ – Langversion 4.0
Z Gastroenterol. 2024 Jan;62(1):e67-e161. doi: 10.1055/a-2189-6353. Epub 2024 Jan 9.NO ABSTRACTPMID:38195102 | DOI:10.1055/a-2189-6353 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - January 9, 2024 Category: Gastroenterology Authors: Michael Bitzer Sabrina Gro ß J örg Albert Susanne Bl ödt Judit Boda-Heggemann Thomas Brunner Reiner Caspari Enrico De Toni Frank Dombrowski Matthias Evert Markus Follmann Paul Freudenberger Cihan Gani Andreas Geier Eleni Gkika Martin G ötz Thomas Helm Source Type: research
S3-Leitlinie „Diagnostik und Therapie des Hepatozellulären Karzinoms“ – Kurzversion
Z Gastroenterol. 2024 Jan;62(1):73-109. doi: 10.1055/a-2189-8461. Epub 2024 Jan 9.NO ABSTRACTPMID:38195103 | DOI:10.1055/a-2189-8461 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - January 9, 2024 Category: Gastroenterology Authors: Sabrina Gro ß Michael Bitzer J örg Albert Susanne Bl ödt Judit Boda-Heggemann Thomas Brunner Reiner Caspari Enrico De Toni Frank Dombrowski Matthias Evert Markus Follmann Paul Freudenberger Cihan Gani Andreas Geier Eleni Gkika Martin G ötz Thomas Helm Source Type: research
Leitlinienreport der S3-Leitlinie „Diagnostik und Therapie des Hepatozellulären Karzinoms und biliärer Karzinome“
Z Gastroenterol. 2024 Jan;62(1):e162-e212. doi: 10.1055/a-2189-6197. Epub 2024 Jan 9.NO ABSTRACTPMID:38195104 | DOI:10.1055/a-2189-6197 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - January 9, 2024 Category: Gastroenterology Authors: Sabrina Gro ß Michael Bitzer Susanne Bl ödt Nadine Fischer Markus Follmann Paul Freudenberger Thomas Langer Petra Lynen Jansen Monika Nothacker Nadine Steubesand Peter R Galle Nisar P Malek Source Type: research
Liver Transplantation meets Cancer
Z Gastroenterol. 2024 Jan;62(1):35-36. doi: 10.1055/a-2179-3157. Epub 2024 Jan 9.NO ABSTRACTPMID:38195105 | DOI:10.1055/a-2179-3157 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - January 9, 2024 Category: Gastroenterology Authors: Dieter P Hoyer Ulf Neumann Source Type: research
Tumour stage and overall survival in patients with intrahepatic cholangiocarcinoma and primary sclerosing cholangitis - a retrospective cohort study
CONCLUSION: Patients with PSC and iCCA showed an advanced tumour stage at diagnosis and limited long-time survival, which was classified between pCCA with worse prognosis and GBC with better prognosis.PMID:38195106 | DOI:10.1055/a-2207-5519 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - January 9, 2024 Category: Gastroenterology Authors: Christoph Schramm Ayaz Sapuk Dieter Hoyer Sonia Rad ünz Hartmut Schmidt Source Type: research
Liver transplantation for HCC in cirrhosis: Are Milan criteria outdated?
We present a retrospective cohort of 111 patients, who underwent liver transplantation at UKSH, Campus Kiel between 2007 and 2017. No difference was found in overall survival for patient cohorts using Milan, UCSF, up-to-seven, and French-AFP criteria. However, there was a significantly reduced survival, if microvascular invasion was detected in the explanted organ and in patients with HCC-recurrence. The exclusive use of static selection criteria including MC appear to limit the access to liver transplantation.PMID:38195107 | PMC:PMC10776328 | DOI:10.1055/a-2228-7496 (Source: Zeitschrift fur Gastroenterologie)
Source: Zeitschrift fur Gastroenterologie - January 9, 2024 Category: Gastroenterology Authors: Jan-Paul Gundlach Mark Ellrichmann Marieke van Rosmalen Serge Vogelaar Christine Eimer Corinna Rheinbay Sabina R ösgen Jost-Philipp Sch äfer Thomas Becker Michael Linecker Felix Braun Source Type: research
Laparoscopic Living donor liver transplantation in irresectable intrahepatic cholangiocarcinoma in primary sclerosing cholangitis associated liver cirrhosis
This report demonstrates the case of an irresectable iCCA in liver cirrhosis due to primary sclerosing cholangitis (PSC) treated by living-donor liver transplantation (LDLT) facilitated by minimal invasive donor hepatectomy. No postoperative complications were observed in the donor and the donor was released on the 6th postoperative day. Further, after a follow-up of 1.5 years, no disease recurrence was detected in the recipient.According to the recent international literature, liver transplantation can be evaluated in case of small solitary iCCA (< 3 cm) in cirrhosis. Less evidence is provided for transplantation in ad...
Source: Zeitschrift fur Gastroenterologie - January 9, 2024 Category: Gastroenterology Authors: Jan Bednarsch Sven A Lang Daniel Heise Pavel Strnad Ulf P Neumann Tom F Ulmer Source Type: research
