Liver transplantation for HCC in cirrhosis: Are Milan criteria outdated?

We present a retrospective cohort of 111 patients, who underwent liver transplantation at UKSH, Campus Kiel between 2007 and 2017. No difference was found in overall survival for patient cohorts using Milan, UCSF, up-to-seven, and French-AFP criteria. However, there was a significantly reduced survival, if microvascular invasion was detected in the explanted organ and in patients with HCC-recurrence. The exclusive use of static selection criteria including MC appear to limit the access to liver transplantation.PMID:38195107 | PMC:PMC10776328 | DOI:10.1055/a-2228-7496

Source: Zeitschrift fur Gastroenterologie - January 9, 2024 Category: Gastroenterology Authors: Jan-Paul Gundlach Mark Ellrichmann Marieke van Rosmalen Serge Vogelaar Christine Eimer Corinna Rheinbay Sabina R ösgen Jost-Philipp Sch äfer Thomas Becker Michael Linecker Felix Braun Source Type: research