Lecithin Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Molecules, Vol. 28, Pages 2823: Biosurfactants: Forthcomings and Regulatory Affairs in Food-Based Industries
ha K. Satpute The terms discussed in this review&mdash;biosurfactants (BSs) and bioemulsifiers (BEs)&mdash;describe surface-active molecules of microbial origin which are popular chemical entities for many industries, including food. BSs are generally low-molecular-weight compounds with the ability to reduce surface tension noticeably, whereas BEs are high-molecular-weight molecules with efficient emulsifying abilities. Some other biomolecules, such as lecithin and egg yolk, are useful as natural BEs in food products. The high toxicity and severe ecological impact of many chemical-based surfactants have...
Source: Molecules - March 21, 2023 Category: Chemistry Authors: Deepansh Sharma Deepti Singh Gadhwal Monika Sukhbir-Singh Bhoomika M. Karamchandani Gajender Kumar Aseri Ibrahim M. Banat Surekha K. Satpute Tags: Review Source Type: research

Molecules, Vol. 28, Pages 2659: Activity and Characterization of Tocopherol Oxidase in Corn Germs and Its Relationship with Oil Color Reversion
In this study, first, the extraction, purification, and detailed characterization of tocopherol oxidase from fresh corn germs were performed. Then, the relationship between the enzyme reaction of &gamma;-tocopherol and oil color reversion was verified. The results showed that the membrane-free extracts of raw corn germ performed specific catalysis of tocopherol in the presence of lecithin. In terms of the oxidation product, tocored (the precursor of color reversion) was detected in the mixture after the catalytic reactions, indicating that this anticipated enzyme reaction was probably correlated with the color reve...
Source: Molecules - March 15, 2023 Category: Chemistry Authors: Liyou Zheng Miaomiao Zhu Fei Zhang Jun Jin Qingzhe Jin Hongyan Guo Tags: Article Source Type: research

Coating with cationic inulin enhances the drug release profile and in vitro anticancer activity of lecithin-based nano drug delivery systems
Int J Biol Macromol. 2023 Mar 9:123955. doi: 10.1016/j.ijbiomac.2023.123955. Online ahead of print.ABSTRACTCore-shell structured lipidic nanoparticles (LNPs) were developed using lecithin sodium acetate (Lec-OAc) ionic complex as a core unit and quaternized inulin (QIn) as the shell part. Inulin (In) was modified using glycidyl trimethyl ammonium chloride (GTMAC) as a positively charged shell part and used for coating the negatively surface charged Lec-OAc. The critical micelle concentration (CMC) of the core was determined as 1.047 × 10-4 M, which is expected to provide high stability in blood circulation as a drug-carry...
Source: International Journal of Biological Macromolecules - March 11, 2023 Category: Biochemistry Authors: Ozgun Vatansever Fatemeh Bahadori Seyma Bulut Mehmet Sayip Eroglu Source Type: research

Deciphering structural aspects of reverse cholesterol transport: mapping the knowns and unknowns
Biol Rev Camb Philos Soc. 2023 Mar 7. doi: 10.1111/brv.12948. Online ahead of print.ABSTRACTAtherosclerosis is a major contributor to the onset and progression of cardiovascular disease (CVD). Cholesterol-loaded foam cells play a pivotal role in forming atherosclerotic plaques. Induction of cholesterol efflux from these cells may be a promising approach in treating CVD. The reverse cholesterol transport (RCT) pathway delivers cholesteryl ester (CE) packaged in high-density lipoproteins (HDL) from non-hepatic cells to the liver, thereby minimising cholesterol load of peripheral cells. RCT takes place via a well-organised in...
Source: Atherosclerosis - March 7, 2023 Category: Cardiology Authors: Sukriti Sacher Abhishek Mukherjee Arjun Ray Source Type: research

Deciphering structural aspects of reverse cholesterol transport: mapping the knowns and unknowns
Biol Rev Camb Philos Soc. 2023 Mar 7. doi: 10.1111/brv.12948. Online ahead of print.ABSTRACTAtherosclerosis is a major contributor to the onset and progression of cardiovascular disease (CVD). Cholesterol-loaded foam cells play a pivotal role in forming atherosclerotic plaques. Induction of cholesterol efflux from these cells may be a promising approach in treating CVD. The reverse cholesterol transport (RCT) pathway delivers cholesteryl ester (CE) packaged in high-density lipoproteins (HDL) from non-hepatic cells to the liver, thereby minimising cholesterol load of peripheral cells. RCT takes place via a well-organised in...
Source: Biological Reviews of the Cambridge Philosophical Society - March 7, 2023 Category: Biology Authors: Sukriti Sacher Abhishek Mukherjee Arjun Ray Source Type: research

Paraoxonase 1 and atherosclerosis
Front Cardiovasc Med. 2023 Feb 16;10:1065967. doi: 10.3389/fcvm.2023.1065967. eCollection 2023.ABSTRACTParaoxonase 1 (PON1), residing almost exclusively on HDL, was discovered because of its hydrolytic activity towards organophosphates. Subsequently, it was also found to hydrolyse a wide range of substrates, including lactones and lipid hydroperoxides. PON1 is critical for the capacity of HDL to protect LDL and outer cell membranes against harmful oxidative modification, but this activity depends on its location within the hydrophobic lipid domains of HDL. It does not prevent conjugated diene formation, but directs lipid p...
Source: Atherosclerosis - March 6, 2023 Category: Cardiology Authors: Paul N Durrington Bilal Bashir Handrean Soran Source Type: research

Choline supplements: An update
In this comprehensive review, we examine the main preclinical and clinical investigations assessing the effects of different forms of choline supplementation currently available, including choline alfoscerate (C8H20NO6P), also known as alpha-glycerophosphocholine (α-GPC, or GPC), choline bitartrate, lecithin, and citicoline, which are cholinergic compounds and precursors of acetylcholine. Extensively used as food supplements, they have been shown to represent an effective strategy for boosting memory and enhancing cognitive function. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - March 6, 2023 Category: Endocrinology Source Type: research

Effect of hydroxypropyl- β-cyclodextrin and lecithin co-stabilized nanoemulsions on the konjac glucomannan/pullulan film
In this study, the various ratio of hydroxypropyl-β-cyclodextrin (HPCD) to lecithin (LEC) was 0:1, 0.5:1, 1:1, 1.5:1 and 2:1 (w/w) co-stabilized cinnamon essential oil (CEO) nanoemulsions were prepared. These nanoemulsions were successfully incorporated in the konjac glucomannan/pullulan polysaccharides-based film matrix. The composition of nanoemulsions and the effect of various nanoemulsions on rheological, mechanical, Water vapor permeability, optical, color, morphology properties, and CEO retention rate of the composite films were characterized. The results demonstrated that HPCD and LEC nanoemulsions had small partic...
Source: International Journal of Biological Macromolecules - February 26, 2023 Category: Biochemistry Authors: Feng Zhou Linman Yu Yang Liu Zhen Zeng Cheng Li Zhengfeng Fang Bin Hu Hong Chen Caixia Wang Saiyan Chen Hejun Wu Wenjuan Wu Yuntao Liu Source Type: research

Synergistic Combination of Irinotecan and Rapamycin Orally Delivered by Nanoemulsion for Enhancing Therapeutic Efficacy of Pancreatic Cancer
This study developed an irinotecan/rapamycin-loaded oral lecithin-based self-nanoemulsifying nanoemulsion preconcentrate (LBSNENPir/ra) and evaluated its synergistic combination effects on pancreatic cancer. LBSNENP loaded with irinotecan and rapamycin at a ratio of 1:1 (LBSNENPir10/ra10) had a better drug release profile and smaller particle size (<200 nm) than the drug powder. Moreover, LBSNENPir10/ra10 exhibited a strong synergistic effect (combination index [CI] < 1.0) in cell viability and combination effect studies. In the tumor inhibition study, the antitumor activity of LBSNENPir10/ra10/sily20 against MIA PaC...
Source: Cancer Control - February 25, 2023 Category: Cancer & Oncology Authors: Yu-Hsuan Liu Ling-Chun Chen Wen-Ting Cheng Pu-Sheng Wei Chien-Ming Hsieh Ming-Thau Sheu Shyr-Yi Lin Hsiu-O Ho Hong-Liang Lin Source Type: research

Soy Lecithin in High ‐Fat Diets Exerts Dual Effects on Adipose Tissue Versus Ileum
ConclusionThe incorporation of SPL in a diet with rapeseed oil exerts differential effect on WAT and ileum, with respectively an inflammation of WAT and an antimicrobial activity in ileum, associated with specific microbiota changes. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - February 17, 2023 Category: Food Science Authors: Charline Buisson, Valentin Leuzy, Emmanuelle Loizon, Emmanuelle Meugnier, Magali Monnoye, Catherine Philippe, Philippe G érard, Marie‐Caroline Michalski, Fabienne Laugerette Tags: Research Article Source Type: research