EGFR-targeted hybrid lipid nanoparticles for chemo-photothermal therapy against colorectal cancer cells
Chem Phys Lipids. 2023 Jan 10;251:105280. doi: 10.1016/j.chemphyslip.2023.105280. Online ahead of print.ABSTRACTAntibody-functionalized targeted nanocarriers have shown great-potential for minimizing the chemoresistance and systemic toxicity of cancer chemotherapies. The combination of chemotherapy and photothermal therapy has great potential in improving therapeutic effect. However, cetuximab-modified nanoparticles based lipids for chemo-phototherapy of EGFR overexpressing colorectal carcinoma (CRC) have seldom been investigated. Hence, this study aimed to fabricate cetuximab-conjugated and near infrared (NIR) light-respo...
Source: Chemistry and Physics of Lipids - January 12, 2023 Category: Lipidology Authors: Fang Fang Xinming Zhang Jin Tang Yu Wang Jinchen Xu Yu Sun Source Type: research

EGFR-targeted hybrid lipid nanoparticles for chemo-photothermal therapy against colorectal cancer cells
Chem Phys Lipids. 2023 Jan 10;251:105280. doi: 10.1016/j.chemphyslip.2023.105280. Online ahead of print.ABSTRACTAntibody-functionalized targeted nanocarriers have shown great-potential for minimizing the chemoresistance and systemic toxicity of cancer chemotherapies. The combination of chemotherapy and photothermal therapy has great potential in improving therapeutic effect. However, cetuximab-modified nanoparticles based lipids for chemo-phototherapy of EGFR overexpressing colorectal carcinoma (CRC) have seldom been investigated. Hence, this study aimed to fabricate cetuximab-conjugated and near infrared (NIR) light-respo...
Source: Chemistry and Physics of Lipids - January 12, 2023 Category: Lipidology Authors: Fang Fang Xinming Zhang Jin Tang Yu Wang Jinchen Xu Yu Sun Source Type: research

EGFR-targeted hybrid lipid nanoparticles for chemo-photothermal therapy against colorectal cancer cells
Chem Phys Lipids. 2023 Jan 10;251:105280. doi: 10.1016/j.chemphyslip.2023.105280. Online ahead of print.ABSTRACTAntibody-functionalized targeted nanocarriers have shown great-potential for minimizing the chemoresistance and systemic toxicity of cancer chemotherapies. The combination of chemotherapy and photothermal therapy has great potential in improving therapeutic effect. However, cetuximab-modified nanoparticles based lipids for chemo-phototherapy of EGFR overexpressing colorectal carcinoma (CRC) have seldom been investigated. Hence, this study aimed to fabricate cetuximab-conjugated and near infrared (NIR) light-respo...
Source: Chemistry and Physics of Lipids - January 12, 2023 Category: Lipidology Authors: Fang Fang Xinming Zhang Jin Tang Yu Wang Jinchen Xu Yu Sun Source Type: research

EGFR-targeted hybrid lipid nanoparticles for chemo-photothermal therapy against colorectal cancer cells
Chem Phys Lipids. 2023 Jan 10;251:105280. doi: 10.1016/j.chemphyslip.2023.105280. Online ahead of print.ABSTRACTAntibody-functionalized targeted nanocarriers have shown great-potential for minimizing the chemoresistance and systemic toxicity of cancer chemotherapies. The combination of chemotherapy and photothermal therapy has great potential in improving therapeutic effect. However, cetuximab-modified nanoparticles based lipids for chemo-phototherapy of EGFR overexpressing colorectal carcinoma (CRC) have seldom been investigated. Hence, this study aimed to fabricate cetuximab-conjugated and near infrared (NIR) light-respo...
Source: Chemistry and Physics of Lipids - January 12, 2023 Category: Lipidology Authors: Fang Fang Xinming Zhang Jin Tang Yu Wang Jinchen Xu Yu Sun Source Type: research

EGFR-targeted hybrid lipid nanoparticles for chemo-photothermal therapy against colorectal cancer cells
Chem Phys Lipids. 2023 Jan 10;251:105280. doi: 10.1016/j.chemphyslip.2023.105280. Online ahead of print.ABSTRACTAntibody-functionalized targeted nanocarriers have shown great-potential for minimizing the chemoresistance and systemic toxicity of cancer chemotherapies. The combination of chemotherapy and photothermal therapy has great potential in improving therapeutic effect. However, cetuximab-modified nanoparticles based lipids for chemo-phototherapy of EGFR overexpressing colorectal carcinoma (CRC) have seldom been investigated. Hence, this study aimed to fabricate cetuximab-conjugated and near infrared (NIR) light-respo...
Source: Chemistry and Physics of Lipids - January 12, 2023 Category: Lipidology Authors: Fang Fang Xinming Zhang Jin Tang Yu Wang Jinchen Xu Yu Sun Source Type: research