Longevity Conferences Coming up in Late 2022
Conferences are a measure of the health of a field; typically the more conferences one sees, the broader the efforts and the larger the funding. Most of the best conferences relating to aging research, and the longevity industry that has emerged from that research, feature an even mix of entrepreneurs, scientists, and investors. The networking at these conferences leads to the foundation of new ventures and seed funding for young ventures. This is important in a field in which there are many, many opportunities to make progress. Networking makes the world turn; it is an essential part of the messy, human process of bringin...
Source: Fight Aging! - June 30, 2022 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs

Smart Jumpsuit Tracks Motor Development in Children
Researchers at the University of Helsinki in Finland created a smart jumpsuit that can track toddler movements. The idea is to closely monitor motor development and identify any issues early, allowing for earlier interventions. Issues with motor development can be related to wider neurodevelopmental problems, and so tracking a young child’s activity can provide a window into their overall development. Previously, this required someone to sit and watch the child, or footage of them, making it difficult to track kids for long periods of time. The suit required substantial breakthroughs in machine learning to train computer...
Source: Medgadget - June 29, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Neurology Pediatrics HelsinkiUni motor development Source Type: blogs

Why doctors are getting their asses kicked by technology
Physicians have terrible technology, but they refuse to recognize high-tech as a medical specialty. They must integrate technology as they do laboratory science. Physicians are certainly suffering from poorly-designed electronic medical records (EHR), but they are also guilty of wilful blindness in abdicating responsibility for technology in medicine. This must change. Physicians have a higherRead more …Why doctors are getting their asses kicked by technology originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 29, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/drea-burbank" rel="tag" data-wpel-link="internal" > Drea Burbank, MD < /a > < /span > Tags: Physician Health IT Source Type: blogs

When Normal is only Pseudo-Normal, it can deceive the caregivers.
An Aussie friend down under sent me this case. A 70-something male presented with sharp stabbing central CP.  Here is the initial ECG with 7/10 CP:NormalThe pain was resolving, and another ECG was recorded with 3/10 CP:Normal, but compared to the first, the T-waves in V2 and V3 are not as tall.  Hmm.......The pain completely resolved:What do you think?Now there is an all-but-diagnostic terminal T-wave inversion in V2.  This is very subtle Wellens ' .The patient then developed 8/10 stabbing CP again:The T-wave in V2 is again upright, indicating re-occlusion of the LAD.  There is also less T-wave inv...
Source: Dr. Smith's ECG Blog - June 29, 2022 Category: Cardiology Authors: Steve Smith Source Type: blogs

How One Type of Tumor Converts Innate Immune Cells to its Cause
We examined the cross-talk between these two populations of cells. We found that the tumor cells expressed high levels of a protein called macrophage migration inhibitory factor (MIF), and that the myeloid cells had receptors to sense the MIF proteins. This makes them switch their biology and promote, rather than block, tumor growth." The investigators believe this information could be used to create novel therapies against soft-tissue sarcoma. A medication designed to stop cancer cells from expressing MIF could be tested in combination with existing therapies, for example, to see if it improves outcomes for patients. ...
Source: Fight Aging! - June 28, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Asimily Announces Strategic Investment from MemorialCare Innovation Fund to Further its Innovation in IoT Device Security and Risk Management
Continuing to deliver new capabilities such as forensic analysis, Asimily will use the funding to accelerate the development of new platform tools and to expand within the healthcare industry Asimily, a leading risk management platform for IoT devices and web-connected equipment, will accelerate its expansion within the healthcare industry with a strategic investment from MemorialCare Innovation Fund. Announced today, the investment includes participation from Ridge Ventures, which led Asimily’s most recent round. Asimily will also utilize the capital to build and release innovative new capabilities for complete IoT...
Source: EMR and HIPAA - June 28, 2022 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Hospital - Health System Security and Privacy Asimily Brant Heise Health IT Funding Health IT Fundings Health IT Investment Healthcare IoT Healthcare IoT Security Healthcare Security MemorialCare Inn Source Type: blogs

Case of the Week 687
 This week ' s case is generously donated by Dr. Ioana Bujila of the Public Health Agency of Sweden. The patient is a 67 year old woman from Gabon. Blood was examined by direct mount and Giemsa-stained blood films, and the following were identified:These objects are approximately 228 micrometers in length.What is your diagnosis? Are there any additional laboratory analyses that are recommended in this case?  (Source: Creepy Dreadful Wonderful Parasites)
Source: Creepy Dreadful Wonderful Parasites - June 27, 2022 Category: Parasitology Source Type: blogs

Answer to Case 687
 Answer toParasite Case of the Week 687: Loa loaAs noted by Florida Fan, @JuanCGabaldon, Idzi P, Ulrike E. Zelck, Priyanka Gupta, and others, the video clearly shows this to be a sheathed microfilaria, and the Giemsa smear shows the column of nuclei extending all the way to the tip of the tail, thus allowing us to make an identification of Loa loa. The patient ' s travel history (Gabon) also fits with this identification. As Idzi P. mentioned, I like to teach my students that nuclei flow-a flow-a to the tip inLoa loa -a fun learning aid!  Also check out thisbeautiful infographic by @cullen_lilley f...
Source: Creepy Dreadful Wonderful Parasites - June 26, 2022 Category: Parasitology Source Type: blogs

Fight Aging! Newsletter, June 13th 2022
In conclusion, long-term cumulative BP was associated with subsequent cognitive decline, dementia risk, and all-cause mortality in cognitively healthy adults aged ≥50 years. Efforts are required to control long-term systolic BP and pulse pressure and to maintain adequate diastolic BP. Longer-Lived Mammals Tend to Have Lower Expression of Inflammation-Related Genes https://www.fightaging.org/archives/2022/06/longer-lived-mammals-tend-to-have-lower-expression-of-inflammation-related-genes/ Researchers here make a few interesting observations on gene expression data from a range of mammalian species with...
Source: Fight Aging! - June 12, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Cancer Correlates with Increased Risk of Later Onset of Type 2 Diabetes
Researchers here note a correlation between cancer diagnosis and greater risk of later onset of type 2 diabetes. A reasonable guess is that this is mediated by the increased burden of cellular senescence produced by chemotherapy and radiotherapy, though, as the researchers point out, the widely different risks by cancer type may indicate that tumors are metabolically active in ways that specifically promote the metabolic dysfunction that leads to type 2 diabetes. For patients with cancer, prevalent type 2 diabetes at the date of cancer diagnosis is associated with increased cancer-specific and all-cause mortality....
Source: Fight Aging! - June 9, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

THIS device may not nudge your brain into deep sleep
TheWashington Post used this picture of a saline-filled 280-channelGeodesic Head Web1 to illustrate a new wearable device that aims to enhance slow wave sleep (SWS). The device delivers low-level current (0.5 mA) at 0.5 Hz to mimic the frequency of EEG naturally recorded during SWS (0.5-1 Hz). However, this is impossible with saline sensors, which would also dry out well before the night is over.  The WaPo article accurately showed different stages of applying the net, including measuring the head, checking impedences, and filling sensors with saline (above). A published journal article used similar Geo...
Source: The Neurocritic - May 31, 2022 Category: Neuroscience Authors: The Neurocritic Source Type: blogs

TWiV 904: 50 years of reverse transcriptase
Vincent travels to Cold Spring Harbor Laboratory to speak with David Baltimore, John Coffin, and Harold Varmus about the discovery in 1970 of retroviral reverse transcriptase and its impact on life sciences research. (Source: virology blog)
Source: virology blog - May 29, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology reverse transcriptase rna tumor virus viral viruses Source Type: blogs

A 30-something with Chest pain, elevated troponin, with Subtle ST Elevation and hyperacute T-waves.
A 30-something male presented in the middle of the night with several hours of sharp, non-radiating, left sided chest pain.  It was there earlier, went away, and then returned approximately 1 hour prior to arrival. He is a smoker and has some family history of early MI.  Exam and vital signs were normal.Here was the triage ECG:There appears to be diffuse ST Elevation (II, III, aVF with reciprocal STD in aVL, V3-V6, and lead I, with T-waves that appear to be hyperacute (broad and fat, but on the other hand they have no straightening of the ST segment).  ST depression and T-wave inversion in V2 sugge...
Source: Dr. Smith's ECG Blog - May 24, 2022 Category: Cardiology Authors: Steve Smith Source Type: blogs

Monkeypox (MPXV)
List of resources for news, and clinical information.  Last updated: 16th June 2022.  Items added or amended that day markedNEW DynaMed entry on orthopoxvirus infections, free accessNEW-Stat News reports moves to rename the virus strains, so they are not named after specific geographic areas.  The position paper is on virological.org. Sky News is reporting WHO discussion of the same issue.Genetic sequence dataSequence of isolate name MPXV_USA_2022_MA001 in GenBank.Sequence of isolate from Portugal, May 2022, with links (at bottom of page) to sequences isolated in other European countries,...
Source: Browsing - May 19, 2022 Category: Databases & Libraries Tags: monkeypox Source Type: blogs

MPXV (Monkeypox)
List of resources for news, and clinical information.  Last updated: 17th June 2022.  Items added or amended that day markedNEW DynaMed entry on orthopoxvirus infections, free accessBMJ Best Practice entry on poxvirus, NHS Athens or subscription neededName of the virusNEW-BMJ is reporting WHO decision to rename the virus.  (subscription or library access required to view the whole thing).Stat News had previously reported moves to rename the virus strains, so they are not named after specific geographic areas.  The position paper referred to in both Stat and BMJ is on virological.org. ...
Source: Browsing - May 19, 2022 Category: Databases & Libraries Tags: monkeypox Source Type: blogs