Fight Aging! Newsletter, November 7th 2022
In conclusion, the national prevalence of dementia and MCI in 2016 found in this cross-sectional study was similar to that of other US-based studies.
Clearing Microglia Reverses Age-Related Disruption of Sleeping Patterns in Mice
https://www.fightaging.org/archives/2022/11/clearing-microglia-reverses-age-related-disruption-of-sleeping-patterns-in-mice/
Microglia are innate immune cells of the central nervous system. They are analogous to macrophages in the rest of the body, but undertake additional duties relating to the function of neurons and in brain tissue. Microglia become overly active and inflamm...
Source: Fight Aging! - November 6, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Modernizing Medicine To Pay $45 Million To Settle False Claims, Kickback Allegations
EHR vendor Modernizing Medicine has agreed to pay $45 million to the federal government to settle a whistleblower suit alleging that the vendor engaged in varied kickback schemes as well as causing its provider customers to submit false claims.
The lawsuit was filed in 2017 by law firms Phillips and Cohen LLP and Downs Rachlin Martin PLLC. The US Department of Justice joined the case in March 2022, which now targeted founders and executives Dan Cane and Dr. Michael Sherling as well as ModMed, after conducting its own investigation.
The whistleblower in the case is Amanda Long, who joined the company in 2014 and exited her ...
Source: EMR and HIPAA - November 4, 2022 Category: Information Technology Authors: Anne Zieger Tags: Ambulatory C-Suite Leadership EMR-EHR Health IT Company Healthcare IT Amanda Long Dan Cane Dr. Michael Sherling EHR Whistleblower False Claims Healthcare Kickbacks Inform Diagnostics meaningful use Miraca Life Science Modernizi Source Type: blogs
Micelle Technology Detects Airborne SARS-CoV-2
At the Pacific Northwest National Laboratory, researchers have developed micelle technology that can detect minute amounts of SARS-CoV-2 in the air. This new capability could provide invaluable monitoring systems to detect viral contamination in healthcare facilities and beyond. Micelles are somewhat similar to liposomes in that they are both like tiny lipid bubbles. In this instance, the researchers incorporated molecularly imprinted polymer molecules into the wall of the micelles. These molecularly imprinted molecules can bind to the viral spike protein. On viral binding, the polymer molecules cause the micelle to burst,...
Source: Medgadget - November 3, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Public Health covid COVID-19 SARS-CoV-2 Source Type: blogs
Growth Hormone Receptor Knockout in Adipose Tissue Extends Life in Mice
The record for mouse life span is held by growth hormone receptor knockout lineages, approaching a 70% gain, but a lot of that increase is due to early life effects. These animals are very small in comparison to their peers. In comparison, growth hormone receptor knockout in adulthood has a greater impact on female mice than on male mice, and the gain in life span is much reduced. In today's open access paper, researchers demonstrate another approach, generating a lineage of mice in which growth hormone receptor is only disabled in fat tissue. Again, the outcomes are different in male and female mice, and smaller than thos...
Source: Fight Aging! - November 2, 2022 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
What is PT-INR monitoring? Cardiology Basics
INR is short for International Normalized Ratio of Prothrombin Time. It is also called PT-INR. The INR monitoring is used to monitor the dosage of vitamin K antagonists like warfarin. Vitamin K antagonists are used for stroke prevention in atrial fibrillation as well as for deep vein thrombosis and pulmonary embolism. Non vitamin K oral anticoagulants (NOACs), also known as direct oral anticoagulants (DOACs) like dabigatran, rivaroxaban and apixaban do not need INR monitoring. Warfarin is routinely used when there is a mechanical prosthetic valve, to prevent valve thrombosis and thromboembolism. As of now, DOACs are not i...
Source: Cardiophile MD - October 25, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Fight Aging! Newsletter, October 24th 2022
This study shows the uncoupling of lifespan and healthspan parameters (aerobic fitness and spontaneous activity) and provides new insights into SIRT3 function in CR adaptation, fuel utilization, and aging.
HDL Level, Age, and Smoking are the Largest Determinants of Mortality Risk in Old People
https://www.fightaging.org/archives/2022/10/hdl-level-age-and-smoking-are-the-largest-determinants-of-mortality-risk-in-old-people/
An interesting epidemiological study here stratifies the contributions of various metrics to mortality in later life, age 70 and older. The authors find that the largest effects arise...
Source: Fight Aging! - October 23, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Balloon aortic valvuloplasty – Cardiology Basics
Balloon aortic valvuloplasty – Cardiology Basics
Balloon aortic valvuloplasty is enlargement of a narrowed aortic valve using balloon catheters. It is also known as balloon aortic valvotomy.
Balloon aortic valvuloplasty has significant risks and lesser benefits compared other procedures for symptomatic severe aortic stenosis like surgical valve replacement and transcatheter aortic valve implantation or TAVI. Hence it is often considered as a bridge treatment or palliative treatment.
Three important scenarios in which balloon aortic valvuloplasty or BAV is considered are: Bridge to decision, bridge to planned treatmen...
Source: Cardiophile MD - October 22, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Rheumatic heart disease – Cardiology Basics
Rheumatic heart disease – Cardiology Basics
Rheumatic heart disease is a group diseases which occur secondary to heart valve damage from rheumatic fever. Rheumatic fever is a disease in which antibodies produced by the body against streptococci cross react with different tissues in the body, especially the heart.
Group A beta hemolytic streptococci causing sore throat are involved in the pathogenesis of rheumatic fever. Most of the long term damage following rheumatic fever is caused by damage to heart valves . Initial manifestation of rheumatic fever is with polyarthritis, usually of the large joints.
But it does no...
Source: Cardiophile MD - October 22, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
What is cardiogenic shock? Cardiology Basics
When the heart is not able to pump enough blood for perfusing the vital organs and the blood pressure falls, it is known as cardiogenic shock. Most important cause of cardiogenic shock is an acute myocardial infarction. Cardiogenic shock can also occur in other conditions like a fulminant myocarditis. In case of myocardial infarction, it is more likely to occur in those who are older, having multivessel coronary artery disease, and in those with a previous myocardial infarction. Cardiogenic shock is a potentially life threatening condition and needs urgent treatment. Even with treatment about half of those with cardiogeni...
Source: Cardiophile MD - October 20, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
The Future of Treating Aging
Here find a sensible, readable paper discussing the years ahead in the treatment of aging as a medical condition. The potential to slow and reverse aspects of aging, demonstrated in animal studies in the laboratory, is now beginning to reach the clinic. A great shift in the provision of medicine, expectations for health in later life, and priorities in research and development will occur over the next few decades. Where we stand today, with senolytic drugs, the first form of rejuvenation therapy worthy of the name, in initial clinical trials, is merely the opening of a lengthy, world-changing process. The human condition w...
Source: Fight Aging! - October 18, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Weekly Australian Health IT Links – 17 October, 2022.
Here are a few I have come across the last week or so. Note: Each link is followed by a title and a few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.General Comment-----We seem to have an epidemic of cyber leaks this week.Otherwise a few fun bits as usual and a few new apps.-----https://itwire.com/science-news/health/a-free-mobile-app-helps-people-track-early-dementia-diagnosis.htmlThursday, 13 October 2022 11:15A free mobile app helps people track early dementia diagnosisByKenn Anthony MendozaHe...
Source: Australian Health Information Technology - October 17, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
What is DM Cardiology? Cardiology Basics
DM Cardiology (Doctor of Medicine – Cardiology) is a three year full-time course conducted at various medical colleges and institutes of national importance in India. Cardiology is the branch of medicine dealing with cardiovascular disorders.
Selection to the various medical colleges is by the National Eligibility Cum Entrance Test – Super Specialty (NEET-SS), while that to institutes of national importance is by Institute of National Importance Combined Entrance Test (INI CET).
NEET-SS is conducted by the National Board Of Examinations In Medical Sciences, New Delhi. INI CET is conducted by All India Institute of Med...
Source: Cardiophile MD - October 16, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
America is a magnet for global STEM talent
This essay is inspired in part by my recent encounter with a scientist at NASA’s Jet Propulsion Laboratory (JPL). For starters, the National Aeronautics and Space Administration — or NASA for short — is an agency of the U.S. government responsible for America’s space program and aeronautics research. JPL, NASA’s research and development center located
Read more…
America is a magnet for global STEM talent originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 11, 2022 Category: General Medicine Authors: Osmund Agbo, MD Tags: Physician Public Health & Policy Source Type: blogs
What is inappropriate sinus tachycardia? Cardiology Basics
Inappropriate sinus tachycardia (IST) is sinus tachycardia inappropriate to the situation. It is defined as sinus rates above 100 beats per minute at rest or average sinus rate above 90 beats per minute over 24 hours without an underlying cause. Important secondary causes of sinus tachycardia like the use of caffeine, alcohol, nicotine, drugs of abuse like cocaine, increased function of thyroid gland, fever, anxiety, pain, and other illnesses which can increase the heart rate have to be excluded before considering IST.
IST may be either asymptomatic or sometimes associated with palpitation, shortness of breath, near synco...
Source: Cardiophile MD - October 9, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
TWiV 944: Hacking through Borneo with Kathryn Hanley
Kathryn Hanley joins TWiV to discuss her career and the research in her laboratory on the molecular biology, evolution and ecology of emerging RNA viruses and their insect vectors. (Source: virology blog)
Source: virology blog - October 9, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology arbovirus blackfly deforestation dengue virus emergence spillover vesicular stomatitis virus viral viruses vsv West Nile virus Source Type: blogs
