Questions grow about the validity and usefulness of direct-to-consumer blood tests for Alzheimer ’s Disease
For the first time, people worried about their risk of Alzheimer’s disease can go online, order a blood test, and receive results in the privacy of their homes.
This might seem appealing on the surface, but the development has Alzheimer’s researchers and clinicians up in arms.
The Quest Diagnostics blood test, AD-Detect, measures elevated levels of amyloid-beta proteins, a signature characteristic of Alzheimer’s. Introduced in late July, the test is targeted primarily at people 50 and older who suspect their memory and thinking might be impaired and people with a family history of Alzheimer’s or genetic risks for t...
Source: SharpBrains - October 19, 2023 Category: Neuroscience Authors: Judith Graham at Kaiser Health News Tags: Brain/ Mental Health AD-Detect Alzheimer’s Alzheimer’s biomarker amyloid-beta proteins brain health brain pathology cognitive cognitive-symptoms mini-strokes neurology neuropsychologist Quest Diagnostics sleep apnea Source Type: blogs
A 20-something woman with cardiac arrest.
The patient is a 20 something female. She is healthy with no known cardiac disease. She was admitted to the neurology department due to headache and vomiting. She was found to have a viral CNS infection. A few days into her hospital stay she developedchest discomfort and the following ECG was recorded. What do you think? Why such large T-waves? Are these hyperacute T-waves? Are these ECG changes related to the CNS infection perhaps? What disease processes would you put on your list of differential diagnoses?When I saw the ECG of this patient I saw that there was definitely something " off " . I didn ' t get...
Source: Dr. Smith's ECG Blog - October 18, 2023 Category: Cardiology Authors: Magnus Nossen Source Type: blogs
Your Insulin of the Future Could Be " Made in China " if Big PBMs Have a Say in the Matter
Back on June 16, 2022, I published an article on LinkedIn entitled "How the Civica Insulin Announcement May Be Disruptive to the PBM Kickback Scheme" (see the article athttps://www.linkedin.com/pulse/how-civica-insulin-announcement-may-disruptive-pbm-scheme-strumello/ if you wish to read it) which predicted that a growing number of insulin biosimilars whose active pharmaceutical ingredients (API ' s) are cultured in offshore laboratories are forecast to hit the U.S. market in the next few years. According to the FDA and the individual companies whom I also follow on LinkedIn, the U.S. Food and Drug Administration (FDA) typ...
Source: Scott's Web Log - October 15, 2023 Category: Endocrinology Tags: 2023 Congress insulin insulin prices lawmakers PBM Pharmacy Benefit Managers Source Type: blogs
Fight Aging! Newsletter, October 9th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - October 8, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
KCC2 in Alzheimer's Disease
The challenge with most identified mechanisms of disease is that they are not close enough to root causes to be highly influential on the progression of the condition. Particularly in the case of neurodegenerative diseases such as Alzheimer's disease, the condition is very complex, and there is much to be discovered about how dysfunction progresses. That doesn't mean that any given aspect of that progression will prove to be useful enough to make the jump from improvements shown in animal models to a basis for therapy in humans. There are many discoveries in the history of Alzheimer's research that have appeared to be as i...
Source: Fight Aging! - October 6, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Pioneering space race research: G-forces and human physiology
An excerpt from Life at High G-Force: The Quest of Mayo Clinic Researcher Dr. Earl H Wood. Tensions were high in the Aero Medical Laboratory at Mayo Clinic in the fall of 1959. The space race with the Soviet Union to send a human into outer space and eventually to the moon was in full
Read more…
Pioneering space race research: G-forces and human physiology originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 4, 2023 Category: General Medicine Authors: Earl Howard Wood, MD, PhD Tags: Conditions Cardiology Source Type: blogs
What happened to the chemical pathologist?
During my early years as a pediatric hospitalist in the U.K. during the ’80s, a figure that loomed large was the chemical pathologist (CP). The CP was the guardian of the laboratory, and every hospital had one. This fearsome beast was approached with trepidation, as the outcome was likely to be a unique but bruising
Read more…
What happened to the chemical pathologist? originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 1, 2023 Category: General Medicine Authors: Martin C. Young, MD Tags: Conditions Pathology Source Type: blogs
Expert human ECG interpretation and/or the Queen of Hearts could have saved this patient's anterior wall
This is a re-post of an excellent case from 2021. See it again now, along with our new Queen of Hearts functionality. We ' ve come a long way in 2 years! And the pace only quickens.A man in his mid 60s with history of CAD and stents experienced sudden onset epigastric abdominal pain radiating up into his chest at home, waking him from sleep. He called EMS who brought him to the ED. He had active chest pain at the time of triage at 0137 at night, with this triage ECG:What do you think?I sent this ECG, without any text at all, to Dr. Smith, and he replied: " LAD OMI with low certainty. V3 is the one that is convincing. "&nbs...
Source: Dr. Smith's ECG Blog - October 1, 2023 Category: Cardiology Authors: Pendell Source Type: blogs
Diversity Supplement Program Paves the Way for Talented Researchers
“I hope that one day I’m able to increase our understanding of evolution, and I also hope to increase access to research. I want others to know that this space is open to people who look like me, who come from disadvantaged backgrounds, and who are underrepresented in the sciences,” says Nkrumah Grant, Ph.D., a postdoctoral research associate (postdoc) in microbiology and molecular genetics at Michigan State University (MSU) in East Lansing.
Dr. Grant’s work receives support from the NIGMS Diversity Supplement Program (DSP), which is designed to improve the recruitment and training of promising researchers from ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - September 27, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Diseases Microbes Profiles Training Source Type: blogs
Technique Creates Multilayered Tubular Cell Constructs
Researchers at the University of Edinburgh have developed a new method to create multilayered tubes from cells. The technique could be very useful for recreating multilayered tubular constructs that are found in the body, such as the intestines and blood vessels. Accurately modeling such complex structures in the lab could open new doors in terms of medical research and may even pave the way for bioengineered intestinal or vascular constructs that are suitable for implantation in human patients.
The method is called rotational internal flow layer engineering (RIFLE), and is low-cost, rapid and can be used to create cons...
Source: Medgadget - September 12, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Materials edinburghuni Source Type: blogs
Why It Is Important To Understand Multimodal Large Language Models In Healthcare
The future of medicine is undoubtedly inextricably linked to the development of artificial intelligence (AI). Although this revolution has been brewing for years, the past few months marked a major change, as algorithms finally moved out of the specialized labs and into our daily lives.
The public debut of Large Language Models (LLMs), like ChatGPT which became the fastest-growing consumer application of all time, has been a roaring success. LLMs are machine learning models trained on a vast amount of text data which enables them to understand and generate human-like text based on the patterns and structures they̵...
Source: The Medical Futurist - September 5, 2023 Category: Information Technology Authors: Andrea Koncz Tags: TMF Artificial Intelligence in Medicine large language models multimodal AI multimodal large language models multimodal LLM Source Type: blogs
Bonus Features – September 3, 2023 – 60% of cybersecurity incidents impact patient care, the average medical device has six or more security vulnerabilities, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
News and Research
ONC renewed its contract for The Sequoia Project to be the Recognized Coordinating Entity for TEFCA implementation. That process will involve working with seven current Qualified Health Information Network can...
Source: EMR and HIPAA - September 3, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT AION Biosystems Akshay Sharma Alexander Group American Telemedicine Association Asimily ATA Atropos Health BeMe Health Carenet Health Claroty Cognizant Craig Hovda Digital Medicine Society eClinicalWorks eCW E Source Type: blogs
Bridging the Representation Gap in Biomedical Research
“We hope that students come out of our program feeling like they’re part of a community. Many of us feel inadequate or struggle in some way during graduate school—it can be a challenging time. I want to build a community that our students can always come back to for support,” says Elana Ehrlich, Ph.D., the co-director of the Bridges to the Doctorate Research Training Program (B2D) at Towson University in Towson, Maryland, alongside Michelle Snyder, Ph.D..
The Towson B2D is one of several NIGMS-supported B2Ds, which are dedicated to developing a diverse pool of well-trained biomedical scientists who will transiti...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - August 30, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Training Source Type: blogs
Fight Aging! Newsletter, August 28th 2023
In conclusion, we identified 20 genes with significant evolutionary signals unique to long-lived species, which provided new insight into the lifespan extension of mammals and might bring new strategies to extend human lifespan.
« Back to Top
Trials of Xenotransplantation of Pig Organs into Humans Continue
https://www.fightaging.org/archives/2023/08/trials-of-xenotransplantation-of-pig-organs-into-humans-continue/
Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants i...
Source: Fight Aging! - August 27, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
UV-Free Air Decontamination: Interview with Sorel Rothschild, VP at Quantum Innovations
LumaFlo, a medtech company based in Israel, has developed a decontamination technology that does not require UV light, something that can be dangerous for people nearby. The COVID-19 pandemic highlighted the need for safe and effective decontamination technologies for both public spaces and healthcare facilities. However, many such technologies rely on UV light to kill pathogens, but this can also have negative effects on those exposed.
In an effort to create a safer and more effective alternative, LumaFlo has developed a carbon nanostructure based photocatalytic system that is activated through visible light, meaning t...
Source: Medgadget - August 25, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Medicine Public Health Source Type: blogs
