Fight Aging! Newsletter, August 8th 2022
In conclusion, aging research will benefit from a better definition of how specific regulators map onto age-dependent change, considered on a phenotype-by-phenotype basis. Resolving some of these key questions will shed more light on how tractable (or intractable) the biology of aging is. Does Acarbose Extend Life in Short Lived Species via Gut Microbiome Changes? https://www.fightaging.org/archives/2022/08/does-acarbose-extend-life-in-short-lived-species-via-gut-microbiome-changes/ Acarbose is one of a few diabetes medications shown to modestly slow aging in short-lived species. Researchers here take a...
Source: Fight Aging! - August 7, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Lumen: World ’s First Device and App for Real-time Metabolic Feedback
Lumen is the first device and app available to anyone that provides real-time feedback on whether you’re burning carbohydrates or fats. These measurements are usually only made for athletes or patients through special testing centers, hospitals, or clinics, but with Lumen they are now available to everyone, anywhere. Nutrition is a very individualized topic, while metabolism is just as nuanced – one size does not fit all when it comes to diet and nutrition plans – and that’s why dieticians and nutrition coaches can play an important role in health and well-being. However, a personalized diet comes with a need fo...
Source: Medgadget - August 3, 2022 Category: Medical Devices Authors: Alice Ferng Tags: Exclusive Medicine Source Type: blogs

Does Acarbose Extend Life in Short Lived Species via Gut Microbiome Changes?
Acarbose is one of a few diabetes medications shown to modestly slow aging in short-lived species. Researchers here take a look at the evidence for this effect on life span to be mediated by changes in the gut microbiome. The gut microbiome changes with age: the relative numbers of harmful microbes increasing, contributing to the chronic inflammation of aging, while relative numbers of beneficial microbes decreases, causing a reduction in metabolites known to help tissue function. Directly changing the gut microbiome to a more youthful configuration via fecal microbiota transplantation has been shown to improve health and ...
Source: Fight Aging! - August 3, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Cancers Subvert the Immune System to Create a Protective Population of Regulatory T Cells
Researchers here identify distinctive markers for a population of regulatory T cells that act to protect at least some types of tumor tissue from the rest of the immune system. Cancers subvert the immune system in a range of ways, making it blind to cancer cells, and even making immune cells assist in the growth of the cancer. In principle destroying these protective, subverted immune cells could produce a renewed attack on a tumor, or at the very least make it more vulnerable to present therapies, particularly those that encourage immune cells to attack cancer cells. Some types of T cells work to calm their over-...
Source: Fight Aging! - August 1, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Weekly Overseas Health IT Links – 30th July2022.
Here are a few I came across last week.Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment-----https://ehrintelligence.com/news/internal-email-outlines-changes-to-oracle-cerner-ehr-business-unitInternal Email Outlines Changes to Oracle Cerner EHR Business UnitUpon its acquisition, the Cerner EHR business is now called Oracle Health, one of Oracle ’s global industry units (GIUs).ByHannah NelsonJuly 22, 2022 - An internal email from an Oracle executive...
Source: Australian Health Information Technology - July 30, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

How Should RPM Vendors Choose Remote Patient Monitoring Device Suppliers?
The following is a guest article by Jack Wang, the Vice President of AOJ Medical. RPM service and Telehealth are not new topics In the current health care market, and many RPM and Telehealth vendors have already set up services, systems, and applications for specified diseases or target patients. These kinds of vendors also treat remote monitoring devices as a key part of the services, such as different kinds of vital signs monitoring and chronic disease monitoring devices. The benefit of continually monitoring the conditions of the patients provides health care vendors an ongoing status from a technical and data-oriented...
Source: EMR and HIPAA - July 25, 2022 Category: Information Technology Authors: Guest Author Tags: Health IT Company Healthcare IT IT Infrastructure and Dev Ops Telemedicine and Remote Monitoring AOJ Medical FDA Jack Wang Medical Device Manufacturers Remote Patient Monitoring RPM RPM Devices RPM Manufacturers RPM Suppliers Source Type: blogs

A man in his 50s with hypoxemic respiratory failure from COVID pneumonia develops chest pain
Submitted by anonymous, written by Parker Hambright, MD, peer reviewed by Meyers, Smith, McLarenA man in his 50s with a past medical history of hypertension and tobacco use disorder, who tested COVID positive 11 days prior, presented to the emergency department with worsening shortness of breath over several days. He was tachypneic and hypoxemic down to as low as 44% with reportedly good SpO2 waveform before EMS applied noninvasive ventilation with improvement to 85-89%. Although history was limited by extremis, the report is that there was no chest pain at initial presentation, only shortness of breath.Here is his ECG on ...
Source: Dr. Smith's ECG Blog - July 25, 2022 Category: Cardiology Authors: Pendell Source Type: blogs

Weekly Overseas Health IT Links – 23rd July2022.
In this study, researchers sought to determine whether differences in occult hypoxemia treatment existed between people of different races.Occult hypoxemia was defined as arterial blood oxygen saturation of less than 88 percent despite a pulse oximetry reading of 92 percent or more.-----https://healthitsecurity.com/news/security-awareness-and-training-crucial-to-preventing-healthcare-phishing-attacksSecurity Awareness and Training Crucial to Preventing Healthcare Phishing AttacksSecurity awareness and training greatly decreased the likelihood of an employee falling for a healthcare phishing attack, KnowBe4 researchers foun...
Source: Australian Health Information Technology - July 23, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

“ Propensity matching ” in medical research : Definitely, not made in Heaven !
It is likely, that the biggest Impact & influence in current medical research may not come from the IQ of our scientists, their concepts, or the sophistication of the laboratory. Then what? Can you guess? It is the man-made mathematic sub-specality called statistics. We are going to either ratify or reject any research work ( on which we toil) based on the quality of numbers we generate. Such is the critical value of this specialty. Just pause a moment, and think over. How much importance do we give to the credibility and “quality of the interpretation” of any study? We have conveniently left it to our este...
Source: Dr.S.Venkatesan MD - July 19, 2022 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized propensity matching propensity score statistics Source Type: blogs

Cardinal Health ’s Outcomes™ acquires smart prescription platform ScalaMed
Acquisition pivots prescription management to patients, reduces administrative burden and offers connectivity at the point of prescribing Cardinal Health (NYSE:CAH) today announced the acquisition of ScalaMed, a HIPAA-compliant, smart platform that transfers prescriptions directly to patients via a secure mobile app. The acquisition transfers ScalaMed’s technology and assets to Outcomes™, a Cardinal Health company. ScalaMed pivots prescription management from provider to patient, allowing patients to send prescriptions written by their provider directly to any pharmacy for the first fill. The platform offers patient...
Source: EMR and HIPAA - July 14, 2022 Category: Information Technology Authors: Healthcare IT News Tags: Communication and Patient Experience Health IT Company Healthcare IT Brent Stutz Cardinal Health Dr. Tal Rapke ePrescribing Health IT Acquisitions Healthcare M&A NYSE:CAH Prescriptions ScalaMed Source Type: blogs

Bedtime Reading?
For those of you looking for some good (?) bedtime reading, you may be interested in two fun articles that Blaine Mathison and I recently wrote:Blaine A. Mathison, Bobbi S. Pritt, Sleeping with the Enemy: Everything You Need to Know about the Biology, Clinical Significance, and Laboratory Identification of Bed Bugs. Clinical Microbiology Newsletter, Volume 43, Issue 1, 2021, Pages 1-7,https://www.sciencedirect.com/science/article/pii/S019643992030091XBlaine A. Mathison, Bobbi S. Pritt,Don ' t Be a Nit Wit; Know Your Lousy Companions! Clinical Microbiology Newsletter, Volume 44, Issue 13, 2022, Pages 115-122,https...
Source: Creepy Dreadful Wonderful Parasites - July 12, 2022 Category: Parasitology Source Type: blogs

AI-Powered Robot Accelerates Medical Research
Researchers at the RIKEN Center for Biosystems Dynamics Research in Japan have developed an AI-powered robotic system that can perform laboratory experiments in regenerative medicine, learn from the results, and perform iterative rounds of experimentation to achieve a certain goal. In a proof-of-principle, the researchers set the robot the task of optimizing cell culture conditions to create a maximal number of retinal pigment epithelium (RPE) cells. The robot improved the percentage of stem cells within a culture that differentiated into RPE cells from 50% to approximately 90% over six months of experimentation, and th...
Source: Medgadget - July 12, 2022 Category: Medical Devices Authors: Conn Hastings Tags: etc. Medicine News medical robotics RIKEN Source Type: blogs

How physicians are mishandling technology
Physicians are getting their asses kicked by technology, but this is reversible if they integrate technology as they do laboratory science. Medicine needs specialized doctors who only focus on technology. This will combat burnout and take control of a system that has no other incentive to adapt to clinical needs. In 2013, I graduated medicalRead more …How physicians are mishandling technology originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 10, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/drea-burbank" rel="tag" data-wpel-link="internal" > Drea Burbank, MD < /a > < /span > Tags: Tech Health IT Source Type: blogs

On the Effectiveness of Flight Ban Strategies in the Fight Against COVID-19 Variants of Concern
Xiaoqian Sun (Beihang University), Sebastian Wandelt (Beijing Key Laboratory for Network-based Cooperative ATM), Changhong Zheng (Beihang University), Anming Zhang (University of British Columbia), On the Effectiveness of Flight Ban Strategies in the Fight Against COVID-19 Variants of Concern, SSRN (2022):... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - July 10, 2022 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Fight Aging! Newsletter, July 4th 2022
This study showed that centenarians had very specific changes in CD4+ T cell populations, which were manifested by an elevated Th17/Treg ratio in vivo, as well as a changed secretory phenotype. Although the T cells of centenarians cannot resist the aging-related expression of proinflammatory genes, their secretory phenotype was altered, explaining the relatively low level of inflammation in centenarians. These results suggested the presence of a mechanism to ameliorate inflammaging in centenarians. This may be achieved by reversing the imbalance of Th17/Treg cells and reducing pro-inflammatory cytokines. Longevit...
Source: Fight Aging! - July 3, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs