Winogradskyella immobilis sp. nov., an Alginate-Hydrolyzing Bacterium Isolated from the Brown Algae Saccharina japonica
Curr Microbiol. 2023 Oct 14;80(12):370. doi: 10.1007/s00284-023-03474-y.ABSTRACTA novel bacterium, designated E313T, was isolated from brown algae Saccharina japonica in Weihai, China. The strain is a Gram-stain-negative, non-flagellated, non-gliding, aerobic, rod-shaped bacterium that grows optimally at 28 °C with pH levels between 7.0 and 7.5 and in the presence of 2-3% (w/v) NaCl. Phylogenetic analyses based on its 16S rRNA gene sequence placed the strain within the monophyletic cluster of the genus Winogradskyella, exhibiting the highest similarity to Winogradskyella wandonensis KCTC 32579T (96.8%). Genome comparison ...
Source: Current Microbiology - October 14, 2023 Category: Microbiology Authors: Shu-Xin Wang Ya-Wei Wang Lu Ma Jing An Ya Gong Zong-Jun Du Source Type: research
Antimetastatic effect of fucoidan against non-small cell lung cancer by suppressing non-receptor tyrosine kinase and extracellular signal-related kinase pathway
CONCLUSIONS: Our data conclude that fucoidan exhibits anti-migratory activities against lung cancer A549 cells mediated by inhibiting ERK1/2 and FAK-Src pathway.PMID:37780215 | PMC:PMC10522815 | DOI:10.4162/nrp.2023.17.5.844 (Source: Cell Research)
Source: Cell Research - October 2, 2023 Category: Cytology Authors: Nareenath Muneerungsee Supita Tanasawet Wanida Sukketsiri Source Type: research
Effects of Alginic Acid on the Porcine Granulosa Cells and Maturation of Porcine Oocytes
ConclusionThese findings suggest that 20 µM AA is toxic to sow reproduction by interfering with estrogen production, oxidative stress, mitochondria-mediated apoptosis, autophagy in GCs of sows, and oocyte maturation. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - September 29, 2023 Category: Food Science Authors: Jinjie Wang,
Yankun Li,
Huan Yuan,
Shengjie Shi,
Lutong Zhang,
Gongshe Yang,
Weijun Pang,
Lei Gao,
Chuanjiang Cai,
Guiyan Chu Tags: Research Article Source Type: research
Diatom-derived mesoporous silica nanoparticles loaded with fucoidan for enhanced chemo-photodynamic therapy
In this study, the focus was on the design of a combination therapy of chemotherapy and PDT. They synthesized diatomaceous earth mesoporous silica nanoparticles (dMSN) containing lanthanide metal ions in a PDT composition. These nanoparticles can generate ROS under near-infrared light irradiation and have MRI and fluorescence imaging capabilities, confirming their phototherapeutic effect on HCT116 cancer cells at a 200 μg/mL concentration. Fucoidan, derived from brown algae, was used as the chemotherapy component. The fucoidan extracted from Sargassum oligocystum in Pingtung Haikou showed the highest anticancer activity, ...
Source: International Journal of Biological Macromolecules - September 28, 2023 Category: Biochemistry Authors: Min-Hsuan Tsou Zhi-Yuan Wu Guan-Wei Chen Cheng-Chang Lee Zui-Harng Lee Wei Ting Yuan Showe-Mei Lin Hsiu-Mei Lin Source Type: research
Diatom-derived mesoporous silica nanoparticles loaded with fucoidan for enhanced chemo-photodynamic therapy
In this study, the focus was on the design of a combination therapy of chemotherapy and PDT. They synthesized diatomaceous earth mesoporous silica nanoparticles (dMSN) containing lanthanide metal ions in a PDT composition. These nanoparticles can generate ROS under near-infrared light irradiation and have MRI and fluorescence imaging capabilities, confirming their phototherapeutic effect on HCT116 cancer cells at a 200 μg/mL concentration. Fucoidan, derived from brown algae, was used as the chemotherapy component. The fucoidan extracted from Sargassum oligocystum in Pingtung Haikou showed the highest anticancer activity, ...
Source: International Journal of Biological Macromolecules - September 28, 2023 Category: Biochemistry Authors: Min-Hsuan Tsou Zhi-Yuan Wu Guan-Wei Chen Cheng-Chang Lee Zui-Harng Lee Wei Ting Yuan Showe-Mei Lin Hsiu-Mei Lin Source Type: research
Macroalgae culture-induced carbon sink in a large cultivation area of China
Environ Sci Pollut Res Int. 2023 Sep 23. doi: 10.1007/s11356-023-29985-6. Online ahead of print.ABSTRACTMacroalgae culture-induced carbon sink in sediments has been little investigated. Here, total organic carbon (TOC), total nitrogen (TN), and δ13C were examined in sediments in a cultivation field of macroalgae (kelp and Gracilariopsis lemaneiformis) in Sansha Bay, Southeast China. Both proxies of C/N (TOC to TN ratio) and δ13C indicated a multisource of TOC. Based on a three-endmember model, macroalgae-derived TOC (TOCma) accounted for < 35% of the total TOC, averaging 16 ± 9% (mean ± SD). On average, terrestrial ...
Source: Environmental Science and Pollution Research International - September 23, 2023 Category: Environmental Health Authors: Yingying Wang Weifeng Yang Yihua Cai Ziming Fang Xiufeng Zhao Qinghua Zhang Hao Yuan Na Lin Chenyi Zou Minfang Zheng Source Type: research
Isolation and characterization of glutathione S-transferase genes and their transcripts in Saccharina japonica (Laminariales, Phaeophyceae) during development and under abiotic stress
Glutathione S-transferase (GST) is a crucial enzyme for metabolism, detoxification, and stress resistance in organisms. Many GSTs have been identified in seaweeds, but the isolation and functional analysis of ... (Source: BMC Plant Biology)
Source: BMC Plant Biology - September 18, 2023 Category: Biology Authors: Chang Lu, Pengyan Zhang, Shuang Li, Mengzhen Cheng and Delin Duan Tags: Research Source Type: research
A scaffolded and annotated reference genome of giant kelp (Macrocystis pyrifera)
Macrocystis pyrifera (giant kelp), is a brown macroalga of great ecological importance as a primary producer and structure-forming foundational species that provides habitat for hundreds of species. It has many c... (Source: BMC Genomics)
Source: BMC Genomics - September 13, 2023 Category: Genetics & Stem Cells Authors: Jose Diesel, Gary Molano, Gabriel J. Montecinos, Kelly DeWeese, Sara Calhoun, Alan Kuo, Anna Lipzen, Asaf Salamov, Igor V. Grigoriev, Daniel C. Reed, Robert J. Miller, Sergey V. Nuzhdin and Filipe Alberto Tags: Research Source Type: research
A Review on the Cytotoxicity and Antibacterial Effect of Marine Organisms of Persian Gulf
Adv Biomed Res. 2023 Jul 27;12:195. doi: 10.4103/abr.abr_290_22. eCollection 2023.ABSTRACTMarine organisms contain several natural products and bioactive compounds, including hydrolyzed proteins, antioxidant peptides, gelatin, collagen, ω-3 unsaturated fatty acids, vitamin A, vitamin D, calcium phosphate, hydroxyapatite, chitosan, lectin, and various toxins. They can inhibit diverse diseases, be used in pharmaceutical compounds, or as antibiotics and pigments. In this regard, these microorganisms are of crucial medicinal and economical importance. Thanks to new technologies and advanced laboratory methods, bioactive compo...
Source: Biomed Res - September 11, 2023 Category: Research Authors: Seyed Erfan Mousavi Sheyda Razaghi Nafiseh Emami Afsaneh Yegdaneh Source Type: research
A Review on the Cytotoxicity and Antibacterial Effect of Marine Organisms of Persian Gulf
Adv Biomed Res. 2023 Jul 27;12:195. doi: 10.4103/abr.abr_290_22. eCollection 2023.ABSTRACTMarine organisms contain several natural products and bioactive compounds, including hydrolyzed proteins, antioxidant peptides, gelatin, collagen, ω-3 unsaturated fatty acids, vitamin A, vitamin D, calcium phosphate, hydroxyapatite, chitosan, lectin, and various toxins. They can inhibit diverse diseases, be used in pharmaceutical compounds, or as antibiotics and pigments. In this regard, these microorganisms are of crucial medicinal and economical importance. Thanks to new technologies and advanced laboratory methods, bioactive compo...
Source: Biomed Res - September 11, 2023 Category: Research Authors: Seyed Erfan Mousavi Sheyda Razaghi Nafiseh Emami Afsaneh Yegdaneh Source Type: research
Cost-effective production of alginate oligosaccharides from Laminaria japonica roots by Pseudoalteromonas agarivorans A3
Alginate oligosaccharides (AOs) are the degradation products of alginate, a natural polysaccharide abundant in brown algae. AOs generated by enzymatic hydrolysis have diverse bioactivities and show broad appli... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - September 9, 2023 Category: Microbiology Authors: Xiao-Hui Sun, Xiu-Lan Chen, Xiao-Fei Wang, Xin-Ru Zhang, Xiao-Meng Sun, Mei-Ling Sun, Xi-Ying Zhang, Yu-Zhong Zhang, Yu-Qiang Zhang and Fei Xu Tags: Research Source Type: research
New investigation of anti-inflammatory activity of Polycladia crinita and biosynthesized selenium nanoparticles: isolation and characterization
Marine macroalgae have gained interest recently, mostly due to their bioactive components. Polycladia crinita is an example of marine macroalgae from the Phaeophyceae class, also known as brown algae. They are ch... (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - September 5, 2023 Category: Microbiology Authors: Alanood S. Almurshedi, Thanaa A. El-Masry, Hend Selim, Mostafa M. El-Sheekh, Mofida E. M. Makhlof, Basmah N. Aldosari, Iman M. Alfagih, Bushra T. AlQuadeib, Salma S. Almarshidy and Maisra M. El-Bouseary Tags: Research Source Type: research
Formulation of a thermo-sensitive hydro-gel for ulcerative colitis treatment
Bioinformation. 2022 Oct 31;18(10):925-937. doi: 10.6026/97320630018925. eCollection 2022.ABSTRACTUlcerative colitis (UC) is a type of inflammatory bowel disease (IBD) that causes chronic intestinal inflammation in gastrointestinal (GI) tract, mainly in innermost lining of colonic mucosa. In any of the UC drug therapy regimens, maintaining remission is challenging and about 20-40% of patients don't respond to conventional UC medications, namely, amino salicylates, steroids and immunosuppressive drugs. These agents can weaken the patient's immune system thus enhancing the risk of infectious diseases. Therefore, in our explo...
Source: Bioinformation - September 1, 2023 Category: Bioinformatics Authors: Deepa Sathesh K Sathesh Kumar Velmurugan Devadasan Sujatha Kuppusamy Source Type: research
Formulation of a thermo-sensitive hydro-gel for ulcerative colitis treatment
Bioinformation. 2022 Oct 31;18(10):925-937. doi: 10.6026/97320630018925. eCollection 2022.ABSTRACTUlcerative colitis (UC) is a type of inflammatory bowel disease (IBD) that causes chronic intestinal inflammation in gastrointestinal (GI) tract, mainly in innermost lining of colonic mucosa. In any of the UC drug therapy regimens, maintaining remission is challenging and about 20-40% of patients don't respond to conventional UC medications, namely, amino salicylates, steroids and immunosuppressive drugs. These agents can weaken the patient's immune system thus enhancing the risk of infectious diseases. Therefore, in our explo...
Source: Bioinformation - September 1, 2023 Category: Bioinformatics Authors: Deepa Sathesh K Sathesh Kumar Velmurugan Devadasan Sujatha Kuppusamy Source Type: research
Formulation of a thermo-sensitive hydro-gel for ulcerative colitis treatment
Bioinformation. 2022 Oct 31;18(10):925-937. doi: 10.6026/97320630018925. eCollection 2022.ABSTRACTUlcerative colitis (UC) is a type of inflammatory bowel disease (IBD) that causes chronic intestinal inflammation in gastrointestinal (GI) tract, mainly in innermost lining of colonic mucosa. In any of the UC drug therapy regimens, maintaining remission is challenging and about 20-40% of patients don't respond to conventional UC medications, namely, amino salicylates, steroids and immunosuppressive drugs. These agents can weaken the patient's immune system thus enhancing the risk of infectious diseases. Therefore, in our explo...
Source: Bioinformation - September 1, 2023 Category: Bioinformatics Authors: Deepa Sathesh K Sathesh Kumar Velmurugan Devadasan Sujatha Kuppusamy Source Type: research
