Environmentally benign alginate extraction and fibres spinning from different European Brown algae species
Int J Biol Macromol. 2022 Dec 8:S0141-8130(22)02871-9. doi: 10.1016/j.ijbiomac.2022.11.306. Online ahead of print.NO ABSTRACTPMID:36502944 | DOI:10.1016/j.ijbiomac.2022.11.306 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - December 12, 2022 Category: Biochemistry Authors: Mariana P Silva Ishrat Jahan Badruddin Thierry Tonon Sameer Rahatekar Leonardo D Gomez Source Type: research

Antihyperglycemic Activity of Nanoemulsion of Brown Algae  (Sargassum.sp) Ethanol Extract in Glucose Tolerance Test in Male Mice
Ann Pharm Fr. 2022 Dec 1:S0003-4509(22)00154-7. doi: 10.1016/j.pharma.2022.11.011. Online ahead of print.NO ABSTRACTPMID:36464073 | DOI:10.1016/j.pharma.2022.11.011 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - December 4, 2022 Category: Drugs & Pharmacology Authors: Agung Giri Samudra Nurfijrin Ramadhani Reza Pertiwi Dyah Fitriani K Fathnur Sani Asril Burhan Source Type: research

Systems pharmacology-based drug discovery and active mechanism of phlorotannins for type 2 diabetes mellitus by integrating network pharmacology and experimental evaluation
In conclusion, the results showed the value of phlorotannins treating on T2DM. Moreover, this study has great significance for improving the medicinal value of phlorotannins and screening natural products for the treatment of T2DM.PMID:36385377 | DOI:10.1111/jfbc.14492 (Source: Atherosclerosis)
Source: Atherosclerosis - November 17, 2022 Category: Cardiology Authors: Jialiang Chen Ping Li Shuhong Ye Wei Li Ming Li Yan Ding Source Type: research

Synergy of the Two Alginate Lyase Domains of a Novel Alginate Lyase from < em > Vibrio < /em > sp. NC2 in Alginate Degradation
This study provides new insight into bacterial alginate lyases and alginate degradation and is helpful for designing multimodular enzymes for efficient alginate depolymerization. IMPORTANCE Alginate is a major component in the cell walls of brown algae. Alginate degradation is carried out by alginate lyases. Until now, while most characterized alginate lyases contain one single catalytic domain, only a few have been shown to contain two catalytic domains. Furthermore, the synergy of alginate lyases has attracted increasing attention since it plays important roles in microbial alginate utilization and biotechnological appli...
Source: Applied and Environmental Microbiology - November 17, 2022 Category: Microbiology Authors: Xiao-Han Wang Xiao-Hui Sun Xiu-Lan Chen Ping-Yi Li Qi-Long Qin Yu-Qiang Zhang Fei Xu Source Type: research

Systems pharmacology-based drug discovery and active mechanism of phlorotannins for type 2 diabetes mellitus by integrating network pharmacology and experimental evaluation
In conclusion, the results showed the value of phlorotannins treating on T2DM. Moreover, this study has great significance for improving the medicinal value of phlorotannins and screening natural products for the treatment of T2DM.PMID:36385377 | DOI:10.1111/jfbc.14492 (Source: Atherosclerosis)
Source: Atherosclerosis - November 17, 2022 Category: Cardiology Authors: Jialiang Chen Ping Li Shuhong Ye Wei Li Ming Li Yan Ding Source Type: research

Synergy of the Two Alginate Lyase Domains of a Novel Alginate Lyase from < em > Vibrio < /em > sp. NC2 in Alginate Degradation
This study provides new insight into bacterial alginate lyases and alginate degradation and is helpful for designing multimodular enzymes for efficient alginate depolymerization. IMPORTANCE Alginate is a major component in the cell walls of brown algae. Alginate degradation is carried out by alginate lyases. Until now, while most characterized alginate lyases contain one single catalytic domain, only a few have been shown to contain two catalytic domains. Furthermore, the synergy of alginate lyases has attracted increasing attention since it plays important roles in microbial alginate utilization and biotechnological appli...
Source: Applied and Environmental Microbiology - November 17, 2022 Category: Microbiology Authors: Xiao-Han Wang Xiao-Hui Sun Xiu-Lan Chen Ping-Yi Li Qi-Long Qin Yu-Qiang Zhang Fei Xu Source Type: research

Synergy of the Two Alginate Lyase Domains of a Novel Alginate Lyase from < em > Vibrio < /em > sp. NC2 in Alginate Degradation
This study provides new insight into bacterial alginate lyases and alginate degradation and is helpful for designing multimodular enzymes for efficient alginate depolymerization. IMPORTANCE Alginate is a major component in the cell walls of brown algae. Alginate degradation is carried out by alginate lyases. Until now, while most characterized alginate lyases contain one single catalytic domain, only a few have been shown to contain two catalytic domains. Furthermore, the synergy of alginate lyases has attracted increasing attention since it plays important roles in microbial alginate utilization and biotechnological appli...
Source: Applied and Environmental Microbiology - November 17, 2022 Category: Microbiology Authors: Xiao-Han Wang Xiao-Hui Sun Xiu-Lan Chen Ping-Yi Li Qi-Long Qin Yu-Qiang Zhang Fei Xu Source Type: research

Synergy of the Two Alginate Lyase Domains of a Novel Alginate Lyase from < em > Vibrio < /em > sp. NC2 in Alginate Degradation
This study provides new insight into bacterial alginate lyases and alginate degradation and is helpful for designing multimodular enzymes for efficient alginate depolymerization. IMPORTANCE Alginate is a major component in the cell walls of brown algae. Alginate degradation is carried out by alginate lyases. Until now, while most characterized alginate lyases contain one single catalytic domain, only a few have been shown to contain two catalytic domains. Furthermore, the synergy of alginate lyases has attracted increasing attention since it plays important roles in microbial alginate utilization and biotechnological appli...
Source: Applied and Environmental Microbiology - November 17, 2022 Category: Microbiology Authors: Xiao-Han Wang Xiao-Hui Sun Xiu-Lan Chen Ping-Yi Li Qi-Long Qin Yu-Qiang Zhang Fei Xu Source Type: research

< em > Sargassum horneri (Turner) C. Agardh < /em > Extract Regulates Neuroinflammation In Vitro and In Vivo
Curr Issues Mol Biol. 2022 Nov 3;44(11):5416-5426. doi: 10.3390/cimb44110367.ABSTRACTPreviously, we reported that Sargassum horneri (Turner) C. Agardh (S. horneri) is a brown algae species that exerts anti-inflammatory activity toward murine macrophages. However, the anti-neuroinflammatory effects and the mechanism of S. horneri on microglia cells are still unknown. We investigated the anti-neuroinflammatory effects of S. horneri extract on microglia in vitro and in vivo. In the present study, we found that S. horneri was not cytotoxic to BV-2 microglia cells and it significantly decreased lipopolysaccharide (LPS)-induced ...
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Jun Hwi Cho Dae Hyun Kim Jong Suk Lee Mi-Suk Seo Mi Eun Kim Jun Sik Lee Source Type: research

< em > Sargassum horneri (Turner) C. Agardh < /em > Extract Regulates Neuroinflammation In Vitro and In Vivo
Curr Issues Mol Biol. 2022 Nov 3;44(11):5416-5426. doi: 10.3390/cimb44110367.ABSTRACTPreviously, we reported that Sargassum horneri (Turner) C. Agardh (S. horneri) is a brown algae species that exerts anti-inflammatory activity toward murine macrophages. However, the anti-neuroinflammatory effects and the mechanism of S. horneri on microglia cells are still unknown. We investigated the anti-neuroinflammatory effects of S. horneri extract on microglia in vitro and in vivo. In the present study, we found that S. horneri was not cytotoxic to BV-2 microglia cells and it significantly decreased lipopolysaccharide (LPS)-induced ...
Source: Mol Biol Cell - November 10, 2022 Category: Molecular Biology Authors: Jun Hwi Cho Dae Hyun Kim Jong Suk Lee Mi-Suk Seo Mi Eun Kim Jun Sik Lee Source Type: research

< em > Sargassum horneri (Turner) C. Agardh < /em > Extract Regulates Neuroinflammation In Vitro and In Vivo
Curr Issues Mol Biol. 2022 Nov 3;44(11):5416-5426. doi: 10.3390/cimb44110367.ABSTRACTPreviously, we reported that Sargassum horneri (Turner) C. Agardh (S. horneri) is a brown algae species that exerts anti-inflammatory activity toward murine macrophages. However, the anti-neuroinflammatory effects and the mechanism of S. horneri on microglia cells are still unknown. We investigated the anti-neuroinflammatory effects of S. horneri extract on microglia in vitro and in vivo. In the present study, we found that S. horneri was not cytotoxic to BV-2 microglia cells and it significantly decreased lipopolysaccharide (LPS)-induced ...
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Jun Hwi Cho Dae Hyun Kim Jong Suk Lee Mi-Suk Seo Mi Eun Kim Jun Sik Lee Source Type: research

< em > Sargassum horneri (Turner) C. Agardh < /em > Extract Regulates Neuroinflammation In Vitro and In Vivo
Curr Issues Mol Biol. 2022 Nov 3;44(11):5416-5426. doi: 10.3390/cimb44110367.ABSTRACTPreviously, we reported that Sargassum horneri (Turner) C. Agardh (S. horneri) is a brown algae species that exerts anti-inflammatory activity toward murine macrophages. However, the anti-neuroinflammatory effects and the mechanism of S. horneri on microglia cells are still unknown. We investigated the anti-neuroinflammatory effects of S. horneri extract on microglia in vitro and in vivo. In the present study, we found that S. horneri was not cytotoxic to BV-2 microglia cells and it significantly decreased lipopolysaccharide (LPS)-induced ...
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Jun Hwi Cho Dae Hyun Kim Jong Suk Lee Mi-Suk Seo Mi Eun Kim Jun Sik Lee Source Type: research

< em > Sargassum horneri (Turner) C. Agardh < /em > Extract Regulates Neuroinflammation In Vitro and In Vivo
Curr Issues Mol Biol. 2022 Nov 3;44(11):5416-5426. doi: 10.3390/cimb44110367.ABSTRACTPreviously, we reported that Sargassum horneri (Turner) C. Agardh (S. horneri) is a brown algae species that exerts anti-inflammatory activity toward murine macrophages. However, the anti-neuroinflammatory effects and the mechanism of S. horneri on microglia cells are still unknown. We investigated the anti-neuroinflammatory effects of S. horneri extract on microglia in vitro and in vivo. In the present study, we found that S. horneri was not cytotoxic to BV-2 microglia cells and it significantly decreased lipopolysaccharide (LPS)-induced ...
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Jun Hwi Cho Dae Hyun Kim Jong Suk Lee Mi-Suk Seo Mi Eun Kim Jun Sik Lee Source Type: research

< em > Sargassum horneri (Turner) C. Agardh < /em > Extract Regulates Neuroinflammation In Vitro and In Vivo
Curr Issues Mol Biol. 2022 Nov 3;44(11):5416-5426. doi: 10.3390/cimb44110367.ABSTRACTPreviously, we reported that Sargassum horneri (Turner) C. Agardh (S. horneri) is a brown algae species that exerts anti-inflammatory activity toward murine macrophages. However, the anti-neuroinflammatory effects and the mechanism of S. horneri on microglia cells are still unknown. We investigated the anti-neuroinflammatory effects of S. horneri extract on microglia in vitro and in vivo. In the present study, we found that S. horneri was not cytotoxic to BV-2 microglia cells and it significantly decreased lipopolysaccharide (LPS)-induced ...
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Jun Hwi Cho Dae Hyun Kim Jong Suk Lee Mi-Suk Seo Mi Eun Kim Jun Sik Lee Source Type: research

< em > Sargassum horneri (Turner) C. Agardh < /em > Extract Regulates Neuroinflammation In Vitro and In Vivo
Curr Issues Mol Biol. 2022 Nov 3;44(11):5416-5426. doi: 10.3390/cimb44110367.ABSTRACTPreviously, we reported that Sargassum horneri (Turner) C. Agardh (S. horneri) is a brown algae species that exerts anti-inflammatory activity toward murine macrophages. However, the anti-neuroinflammatory effects and the mechanism of S. horneri on microglia cells are still unknown. We investigated the anti-neuroinflammatory effects of S. horneri extract on microglia in vitro and in vivo. In the present study, we found that S. horneri was not cytotoxic to BV-2 microglia cells and it significantly decreased lipopolysaccharide (LPS)-induced ...
Source: Current Issues in Molecular Biology - November 10, 2022 Category: Molecular Biology Authors: Jun Hwi Cho Dae Hyun Kim Jong Suk Lee Mi-Suk Seo Mi Eun Kim Jun Sik Lee Source Type: research