Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research

Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Mol Biol Cell - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research

Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research

Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Mol Biol Cell - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research

Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research

Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research

Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research

Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research

Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research

Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research

Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research

Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research

Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research

Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research

Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research