Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research
Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research
Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research
Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research
Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research
Neuroprotective Effects of Water Extract from Brown Algae < em > Petalonia binghamiae < /em > in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
This study investigated the therapeutic effects of the hot water extract of Petalonia binghamiae (wPB), a brown alga, in in vitro and in vivo models of fCI. The neuroprotective efficacy of wPB was evaluated in an in vitro excitotoxicity model established using HT-22 cells challenged with glutamate. Afterward, C57/BL6 mice were administered wPB for 7 days (10 or 100 mg/kg, intragastric) and subjected to middle cerebral artery occlusion and reperfusion (MCAO/R) operation, which was used as an in vivo fCI model. wPB co-incubation significantly inhibited cell death, oxidative stress, and apoptosis, as well as stimulated the ex...
Source: Current Issues in Molecular Biology - October 27, 2023 Category: Molecular Biology Authors: Sun Ho Eom Geum-Lan Hong Hyun Bae Kang Nam-Seob Lee Do Kyung Kim Young Gil Jeong Chun-Sung Kim Yung Choon Yoo Bong Ho Lee Ju-Young Jung Dong-Sub Kim Seung Yun Han Source Type: research
Genes, Vol. 14, Pages 1969: The Draft Genome of the & ldquo;Golden Tide & rdquo; Seaweed, Sargassum horneri: Characterization and Comparative Analysis
This study represents the first genome-wide characterization of a S. horneri species, providing crucial insights for future investigations, such as ecological genomic analyses. (Source: Genes)
Source: Genes - October 21, 2023 Category: Genetics & Stem Cells Authors: Shengqin Wang Mingjiang Wu Tags: Article Source Type: research
Large method differences for free thyroid hormone assays in the hyperthyroid range can affect assessment of hyperthyroid status: comparison of Abbott Alinity to Roche Cobas, Siemens Centaur and equilibrium dialysis LC-MS/MS
CONCLUSION: Measured free thyroid hormone concentrations are highly method-dependent, especially at high FT4 concentrations. Clinicians treating hyperthyroid patients should be aware that patients appear much less hyperthyroid from FT4-measurements performed using Alinity compared to Cobas or Centaur. Guideline-recommended antithyroid drug dosages based on FT4 (including multiples of the upper reference range) have to be adjusted to the FT4 method used. FT4 results from different methods should be clearly distinguished (e.g. separate lines) in medical records.PMID:37848158 | DOI:10.1016/j.clinbiochem.2023.110676 (Source: C...
Source: Clinical Biochemistry - October 17, 2023 Category: Biochemistry Authors: Alexander Bauer Westbye Finn Erik Aas Sandra R Dahl Svetlana N Zykova Oskar Kelp Louise K Dahll Per M Thorsby Source Type: research
Large method differences for free thyroid hormone assays in the hyperthyroid range can affect assessment of hyperthyroid status: comparison of Abbott Alinity to Roche Cobas, Siemens Centaur and equilibrium dialysis LC-MS/MS
CONCLUSION: Measured free thyroid hormone concentrations are highly method-dependent, especially at high FT4 concentrations. Clinicians treating hyperthyroid patients should be aware that patients appear much less hyperthyroid from FT4-measurements performed using Alinity compared to Cobas or Centaur. Guideline-recommended antithyroid drug dosages based on FT4 (including multiples of the upper reference range) have to be adjusted to the FT4 method used. FT4 results from different methods should be clearly distinguished (e.g. separate lines) in medical records.PMID:37848158 | DOI:10.1016/j.clinbiochem.2023.110676 (Source: C...
Source: Clinical Biochemistry - October 17, 2023 Category: Biochemistry Authors: Alexander Bauer Westbye Finn Erik Aas Sandra R Dahl Svetlana N Zykova Oskar Kelp Louise K Dahll Per M Thorsby Source Type: research
Large method differences for free thyroid hormone assays in the hyperthyroid range can affect assessment of hyperthyroid status: Comparison of Abbott Alinity to Roche Cobas, Siemens Centaur and equilibrium dialysis LC-MS/MS
CONCLUSION: Measured free thyroid hormone concentrations are highly method-dependent, especially at high FT4 concentrations. Clinicians treating hyperthyroid patients should be aware that patients appear much less hyperthyroid from FT4-measurements performed using Alinity compared to Cobas or Centaur. Guideline-recommended antithyroid drug dosages based on FT4 (including multiples of the upper reference range) have to be adjusted to the FT4 method used. FT4 results from different methods should be clearly distinguished (e.g. separate lines) in medical records.PMID:37848158 | DOI:10.1016/j.clinbiochem.2023.110676 (Source: C...
Source: Clinical Biochemistry - October 17, 2023 Category: Biochemistry Authors: Alexander Bauer Westbye Finn Erik Aas Sandra R Dahl Svetlana N Zykova Oskar Kelp Louise K Dahll Per M Thorsby Source Type: research
Large method differences for free thyroid hormone assays in the hyperthyroid range can affect assessment of hyperthyroid status: Comparison of Abbott Alinity to Roche Cobas, Siemens Centaur and equilibrium dialysis LC-MS/MS
CONCLUSION: Measured free thyroid hormone concentrations are highly method-dependent, especially at high FT4 concentrations. Clinicians treating hyperthyroid patients should be aware that patients appear much less hyperthyroid from FT4-measurements performed using Alinity compared to Cobas or Centaur. Guideline-recommended antithyroid drug dosages based on FT4 (including multiples of the upper reference range) have to be adjusted to the FT4 method used. FT4 results from different methods should be clearly distinguished (e.g. separate lines) in medical records.PMID:37848158 | DOI:10.1016/j.clinbiochem.2023.110676 (Source: C...
Source: Clinical Biochemistry - October 17, 2023 Category: Biochemistry Authors: Alexander Bauer Westbye Finn Erik Aas Sandra R Dahl Svetlana N Zykova Oskar Kelp Louise K Dahll Per M Thorsby Source Type: research
Large method differences for free thyroid hormone assays in the hyperthyroid range can affect assessment of hyperthyroid status: Comparison of Abbott Alinity to Roche Cobas, Siemens Centaur and equilibrium dialysis LC-MS/MS
CONCLUSION: Measured free thyroid hormone concentrations are highly method-dependent, especially at high FT4 concentrations. Clinicians treating hyperthyroid patients should be aware that patients appear much less hyperthyroid from FT4-measurements performed using Alinity compared to Cobas or Centaur. Guideline-recommended antithyroid drug dosages based on FT4 (including multiples of the upper reference range) have to be adjusted to the FT4 method used. FT4 results from different methods should be clearly distinguished (e.g. separate lines) in medical records.PMID:37848158 | DOI:10.1016/j.clinbiochem.2023.110676 (Source: C...
Source: Clinical Biochemistry - October 17, 2023 Category: Biochemistry Authors: Alexander Bauer Westbye Finn Erik Aas Sandra R Dahl Svetlana N Zykova Oskar Kelp Louise K Dahll Per M Thorsby Source Type: research
Mycoplasma bradburyae sp. nov. isolated from the trachea of sea birds
Syst Appl Microbiol. 2023 Oct 7;46(6):126472. doi: 10.1016/j.syapm.2023.126472. Online ahead of print.ABSTRACTIn the search for mollicutes in wild birds, six Mycoplasma strains were isolated from tracheal swabs taken from four different species of seabirds. Four strains originated from three Yellow-legged gulls (Larus michahellis) and a Cory's shearwater (Calonectris borealis) from Spain, one from a South African Kelp gull (Larus dominicanus), and one from an Italian Black-headed gull (Chroicocephalus ridibundus). These Mycoplasma strains presented 99 % 16S rRNA gene sequence similarity values with Mycoplasma (M.) gallisep...
Source: Systematic and Applied Microbiology - October 15, 2023 Category: Microbiology Authors: Ana S Ram írez Jos é B Poveda Remco Dijkman Carlos Poveda Alejandro Su árez-Pérez Rub én S Rosales Anneke Feberwee Michael P Szostak Lorenzo Ressel Tomeu Viver Pascual Calabuig Salvatore Catania Federica Gobbo Dorina Timofte Joachim Spergser Source Type: research
Mycoplasma bradburyae sp. nov. isolated from the trachea of sea birds
Syst Appl Microbiol. 2023 Oct 7;46(6):126472. doi: 10.1016/j.syapm.2023.126472. Online ahead of print.ABSTRACTIn the search for mollicutes in wild birds, six Mycoplasma strains were isolated from tracheal swabs taken from four different species of seabirds. Four strains originated from three Yellow-legged gulls (Larus michahellis) and a Cory's shearwater (Calonectris borealis) from Spain, one from a South African Kelp gull (Larus dominicanus), and one from an Italian Black-headed gull (Chroicocephalus ridibundus). These Mycoplasma strains presented 99 % 16S rRNA gene sequence similarity values with Mycoplasma (M.) gallisep...
Source: Systematic and Applied Microbiology - October 15, 2023 Category: Microbiology Authors: Ana S Ram írez Jos é B Poveda Remco Dijkman Carlos Poveda Alejandro Su árez-Pérez Rub én S Rosales Anneke Feberwee Michael P Szostak Lorenzo Ressel Tomeu Viver Pascual Calabuig Salvatore Catania Federica Gobbo Dorina Timofte Joachim Spergser Source Type: research
Winogradskyella immobilis sp. nov., an Alginate-Hydrolyzing Bacterium Isolated from the Brown Algae Saccharina japonica
Curr Microbiol. 2023 Oct 14;80(12):370. doi: 10.1007/s00284-023-03474-y.ABSTRACTA novel bacterium, designated E313T, was isolated from brown algae Saccharina japonica in Weihai, China. The strain is a Gram-stain-negative, non-flagellated, non-gliding, aerobic, rod-shaped bacterium that grows optimally at 28 °C with pH levels between 7.0 and 7.5 and in the presence of 2-3% (w/v) NaCl. Phylogenetic analyses based on its 16S rRNA gene sequence placed the strain within the monophyletic cluster of the genus Winogradskyella, exhibiting the highest similarity to Winogradskyella wandonensis KCTC 32579T (96.8%). Genome comparison ...
Source: Current Microbiology - October 14, 2023 Category: Microbiology Authors: Shu-Xin Wang Ya-Wei Wang Lu Ma Jing An Ya Gong Zong-Jun Du Source Type: research
