Novel silver nanoparticle-antibiotic combinations as promising antibacterial and anti-biofilm candidates against multiple-antibiotic resistant ESKAPE microorganisms
This study explores the combination of AgNPs with antibiotics (SACs) to create new antimicrobial agents effective against MAR ESKAPE microorganisms.METHODS: AgNPs were synthesized using Streptococcus pneumoniae ATCC 49619 and characterized for structure and surface properties. The SACs were tested against ESKAPE microorganisms using growth kinetics and time-kill curve methods. The effect of SACs on bacterial biofilms and the disruption of cell membranes was determined. The in-vitro cytotoxicity effect of the AgNPs was also studied.FINDINGS: The synthesized AgNPs (spherical, 7.37±4.55 nm diameter) were antimicrobial agains...
Source: Colloids and Surfaces - March 6, 2024 Category: Biotechnology Authors: Maitri Mishra Anand Ballal Devashish Rath Archana Rath Source Type: research
Epidemiologic analysis of antimicrobial resistance in hospital departments in China from 2022 to 2023
This study suggests that the prevention and control of infections in the respiratory and genitourinary systems should be the focus of anti-infective work and that the use of antimicrobials should be reduced and regulated to prevent the emergence and spread of resistant bacteria.PMID:38449053 | PMC:PMC10918933 | DOI:10.1186/s41043-024-00526-2 (Source: Journal of Health, Population, and Nutrition)
Source: Journal of Health, Population, and Nutrition - March 6, 2024 Category: International Medicine & Public Health Authors: Hui-Jun Bai Qing-Feng Geng Fang Jin Yong-Li Yang Source Type: research
Multidrug ‐resistant Enterococcus faecium strains enter the Norwegian marine environment through treated sewage
This study investigated the prevalence of antibiotic resistance inEnterococcus spp. from raw and treated sewage in Bergen, Norway. We analyzed 307 Enterococcus faecium isolates from raw sewage and 185E. faecium isolates from treated sewage for antibiotic sensitivity and sequenced selected isolates (n = 25). This study found that multidrug-resistantE. faecium clones from clonal complex 17 are entering the marine environment through treated sewage. AbstractThis study aimed to understand the antibiotic resistance prevalence amongEnterococcus spp. from raw and treated sewage in Bergen city, Norway. In total, 517Enterococ...
Source: MicrobiologyOpen - March 6, 2024 Category: Microbiology Authors: Vera Radisic,
Didrik H. Grevskott,
Nadja Junghardt,
Lise Øvreås,
Nachiket P. Marathe Tags: ORIGINAL ARTICLE Source Type: research
Signatures of disease outcome severity in the intestinal fungal and bacterial microbiome of COVID-19 patients
ConclusionsCOVID-19 was associated with opportunistic bacterial pathogens, and Candida was the dominant fungal taxon in the intestine. Together, we found an association between commensal SCFA-producers and a fungal genus that was present in the intestines of patients who did not experience the most severe outcome of the disease. We believe that this taxon could have played a role in the disease outcome, and that further studies should be conducted to understand the role of fungi in gastrointestinal and health protection. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 6, 2024 Category: Microbiology Source Type: research
Polycystic intrahepatic infection caused by Enterococcus casseliflavus: a case report and literature review
This report describes a rare case of polycystic intr... (Source: BMC Nephrology)
Source: BMC Nephrology - March 6, 2024 Category: Urology & Nephrology Authors: Senyin Xu, Bin Huang, Youjun Cao, Zhongyong Zhong and Jiazhen Yin Tags: Case Report Source Type: research
Multiple pathogen contamination of water, hands, and fomites in rural Nepal and the effect of WaSH interventions
This study provides an understanding of WaSH intervention on microbe concentrations. Such data could help with better planning of intervention activities in the future.PMID:38442666 | DOI:10.1016/j.ijheh.2024.114341 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - March 5, 2024 Category: Environmental Health Authors: Sital Uprety Isaac Ngo Marika Maggos Bipin Dangol Samendra P Sherchan Joanna L Shisler Mohan Amarasiri Daisuke Sano Thanh H Nguyen Source Type: research
Multiple pathogen contamination of water, hands, and fomites in rural Nepal and the effect of WaSH interventions
This study provides an understanding of WaSH intervention on microbe concentrations. Such data could help with better planning of intervention activities in the future.PMID:38442666 | DOI:10.1016/j.ijheh.2024.114341 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - March 5, 2024 Category: Environmental Health Authors: Sital Uprety Isaac Ngo Marika Maggos Bipin Dangol Samendra P Sherchan Joanna L Shisler Mohan Amarasiri Daisuke Sano Thanh H Nguyen Source Type: research
Antimicrobial resistance patterns, virulence genes, and biofilm formation in enterococci strains collected from different sources
This study aimed to investigate the antibiotic susceptibility pattern, biofilm formatio... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - March 4, 2024 Category: Infectious Diseases Authors: Maryam Ghazvinian, Saba Asgharzadeh Marghmalek, Mehrdad Gholami, Sanaz Amir Gholami, Elham Amiri and Hamid Reza Goli Tags: Research Source Type: research
Antimicrobial susceptibility prediction from genomes: a dream come true?
Trends Microbiol. 2024 Mar 2:S0966-842X(24)00052-0. doi: 10.1016/j.tim.2024.02.012. Online ahead of print.ABSTRACTGenome-based diagnostics provides relevant information to guide patient treatment and support pathogen and resistance surveillance. Recently, Coll et al. introduced a curated database for predicting antimicrobial resistance (AMR) from Enterococcus faecium genomics data, offering excellent predictive values for susceptibility to important antimicrobials. Challenges to predict resistance to last-resort antimicrobials remain.PMID:38433028 | DOI:10.1016/j.tim.2024.02.012 (Source: Trends in Microbiology)
Source: Trends in Microbiology - March 3, 2024 Category: Microbiology Authors: Guido Werner Hege Vangstein Aamot Natacha Couto Source Type: research
Antimicrobial susceptibility prediction from genomes: a dream come true?
Trends Microbiol. 2024 Mar 2:S0966-842X(24)00052-0. doi: 10.1016/j.tim.2024.02.012. Online ahead of print.ABSTRACTGenome-based diagnostics provides relevant information to guide patient treatment and support pathogen and resistance surveillance. Recently, Coll et al. introduced a curated database for predicting antimicrobial resistance (AMR) from Enterococcus faecium genomics data, offering excellent predictive values for susceptibility to important antimicrobials. Challenges to predict resistance to last-resort antimicrobials remain.PMID:38433028 | DOI:10.1016/j.tim.2024.02.012 (Source: Trends in Microbiology)
Source: Trends in Microbiology - March 3, 2024 Category: Microbiology Authors: Guido Werner Hege Vangstein Aamot Natacha Couto Source Type: research
Antimicrobial susceptibility prediction from genomes: a dream come true?
Trends Microbiol. 2024 Mar 2:S0966-842X(24)00052-0. doi: 10.1016/j.tim.2024.02.012. Online ahead of print.ABSTRACTGenome-based diagnostics provides relevant information to guide patient treatment and support pathogen and resistance surveillance. Recently, Coll et al. introduced a curated database for predicting antimicrobial resistance (AMR) from Enterococcus faecium genomics data, offering excellent predictive values for susceptibility to important antimicrobials. Challenges to predict resistance to last-resort antimicrobials remain.PMID:38433028 | DOI:10.1016/j.tim.2024.02.012 (Source: Trends in Microbiology)
Source: Trends in Microbiology - March 3, 2024 Category: Microbiology Authors: Guido Werner Hege Vangstein Aamot Natacha Couto Source Type: research
Biodiversity and antibiotic resistance profile provide new evidence for a different origin of enterococci in bovine raw milk and feces
Food Microbiol. 2024 Jun;120:104492. doi: 10.1016/j.fm.2024.104492. Epub 2024 Feb 18.ABSTRACTEnterococci are widely distributed in dairy sector. They are commensals of the gastrointestinal tract of animals, thus, via fecal contamination, could reach raw milk and dairy products. The aims of this study were: 1) to investigate the enterococcal diversity in cow feces and milk samples and 2) to evaluate the antibiotic resistance (AR) of dairy-related enterococci and their ability to transfer resistance genes. E. faecalis (59.9%), E. faecium (18.6%) and E. lactis (12.4%) were prevalent in milk, while E. faecium (84.2%) and E. hi...
Source: Food Microbiology - March 2, 2024 Category: Food Science Authors: Stefano Morandi Tiziana Silvetti Vincenzo Lopreiato Fiorenzo Piccioli-Cappelli Erminio Trevisi Milena Brasca Source Type: research
Possibility of transfer and activation of 'silent' tetracycline resistance genes among Enterococcus faecalis under high-pressure processing
In this study, the tetracycline resistance of Enterococcus faecalis strains isolated from food was determined and molecular analyses of the resistance background were performed by determining the frequency of selected tetracycline resistance genes. In addition, the effect of high-pressure stress (400 and 500 MPa) on the expression of selected genes encoding tetracycline resistance was determined, as well as changes in the frequency of transfer of these genes in isolates showing sensitivity to tetracyclines. In our study, we observed an increase in the expression of genes encoding tetracyclines, especially the tet(L) gene, ...
Source: Food Microbiology - March 2, 2024 Category: Food Science Authors: Patryk Wi śniewski Arkadiusz Zakrzewski Wioleta Chaj ęcka-Wierzchowska Anna Zadernowska Source Type: research
Biodiversity and antibiotic resistance profile provide new evidence for a different origin of enterococci in bovine raw milk and feces
Food Microbiol. 2024 Jun;120:104492. doi: 10.1016/j.fm.2024.104492. Epub 2024 Feb 18.ABSTRACTEnterococci are widely distributed in dairy sector. They are commensals of the gastrointestinal tract of animals, thus, via fecal contamination, could reach raw milk and dairy products. The aims of this study were: 1) to investigate the enterococcal diversity in cow feces and milk samples and 2) to evaluate the antibiotic resistance (AR) of dairy-related enterococci and their ability to transfer resistance genes. E. faecalis (59.9%), E. faecium (18.6%) and E. lactis (12.4%) were prevalent in milk, while E. faecium (84.2%) and E. hi...
Source: Food Microbiology - March 2, 2024 Category: Food Science Authors: Stefano Morandi Tiziana Silvetti Vincenzo Lopreiato Fiorenzo Piccioli-Cappelli Erminio Trevisi Milena Brasca Source Type: research
Possibility of transfer and activation of 'silent' tetracycline resistance genes among Enterococcus faecalis under high-pressure processing
In this study, the tetracycline resistance of Enterococcus faecalis strains isolated from food was determined and molecular analyses of the resistance background were performed by determining the frequency of selected tetracycline resistance genes. In addition, the effect of high-pressure stress (400 and 500 MPa) on the expression of selected genes encoding tetracycline resistance was determined, as well as changes in the frequency of transfer of these genes in isolates showing sensitivity to tetracyclines. In our study, we observed an increase in the expression of genes encoding tetracyclines, especially the tet(L) gene, ...
Source: Food Microbiology - March 2, 2024 Category: Food Science Authors: Patryk Wi śniewski Arkadiusz Zakrzewski Wioleta Chaj ęcka-Wierzchowska Anna Zadernowska Source Type: research
