Extracellular vesicles: new bullets in the fungal armory
Trends Microbiol. 2024 Apr 24:S0966-842X(24)00087-8. doi: 10.1016/j.tim.2024.04.002. Online ahead of print.ABSTRACTInvasive fungal infections represent millions of deaths per year, but their pathophysiology remains insufficiently understood. Host-fungi interplay has been recently shown to include extracellular vesicles derived from fungi and host infected cells. In this forum article we discuss their emerging role in modulating the host immune response with particular emphasis on their regulatory involvement during Candida albicans infection.PMID:38664155 | DOI:10.1016/j.tim.2024.04.002 (Source: Trends in Microbiology)
Source: Trends in Microbiology - April 25, 2024 Category: Microbiology Authors: Elise Biquand Sandra Khau Nicolas Papon Benoit Briard Source Type: research
Critically evaluating the relative importance of phage in shaping microbial community composition
Trends Microbiol. 2024 Mar 20:S0966-842X(24)00057-X. doi: 10.1016/j.tim.2024.02.014. Online ahead of print.ABSTRACTThe ubiquity of bacteriophages (phages) and the major evolutionary and ecological impacts they can have on their microbial hosts has resulted in phages often cited as key drivers shaping microbial community composition (the relative abundances of species). However, the evidence for the importance of phages is mixed. Here, we critically review the theory and data exploring the role of phages in communities, identifying the conditions when phages are likely to be important drivers of community composition. At ec...
Source: Trends in Microbiology - April 11, 2024 Category: Microbiology Authors: Meaghan Castledine Angus Buckling Source Type: research
Critically evaluating the relative importance of phage in shaping microbial community composition
Trends Microbiol. 2024 Mar 20:S0966-842X(24)00057-X. doi: 10.1016/j.tim.2024.02.014. Online ahead of print.ABSTRACTThe ubiquity of bacteriophages (phages) and the major evolutionary and ecological impacts they can have on their microbial hosts has resulted in phages often cited as key drivers shaping microbial community composition (the relative abundances of species). However, the evidence for the importance of phages is mixed. Here, we critically review the theory and data exploring the role of phages in communities, identifying the conditions when phages are likely to be important drivers of community composition. At ec...
Source: Trends in Microbiology - April 11, 2024 Category: Microbiology Authors: Meaghan Castledine Angus Buckling Source Type: research
Critically evaluating the relative importance of phage in shaping microbial community composition
Trends Microbiol. 2024 Mar 20:S0966-842X(24)00057-X. doi: 10.1016/j.tim.2024.02.014. Online ahead of print.ABSTRACTThe ubiquity of bacteriophages (phages) and the major evolutionary and ecological impacts they can have on their microbial hosts has resulted in phages often cited as key drivers shaping microbial community composition (the relative abundances of species). However, the evidence for the importance of phages is mixed. Here, we critically review the theory and data exploring the role of phages in communities, identifying the conditions when phages are likely to be important drivers of community composition. At ec...
Source: Trends in Microbiology - April 11, 2024 Category: Microbiology Authors: Meaghan Castledine Angus Buckling Source Type: research
Critically evaluating the relative importance of phage in shaping microbial community composition
Trends Microbiol. 2024 Mar 20:S0966-842X(24)00057-X. doi: 10.1016/j.tim.2024.02.014. Online ahead of print.ABSTRACTThe ubiquity of bacteriophages (phages) and the major evolutionary and ecological impacts they can have on their microbial hosts has resulted in phages often cited as key drivers shaping microbial community composition (the relative abundances of species). However, the evidence for the importance of phages is mixed. Here, we critically review the theory and data exploring the role of phages in communities, identifying the conditions when phages are likely to be important drivers of community composition. At ec...
Source: Trends in Microbiology - April 11, 2024 Category: Microbiology Authors: Meaghan Castledine Angus Buckling Source Type: research
Critically evaluating the relative importance of phage in shaping microbial community composition
Trends Microbiol. 2024 Mar 20:S0966-842X(24)00057-X. doi: 10.1016/j.tim.2024.02.014. Online ahead of print.ABSTRACTThe ubiquity of bacteriophages (phages) and the major evolutionary and ecological impacts they can have on their microbial hosts has resulted in phages often cited as key drivers shaping microbial community composition (the relative abundances of species). However, the evidence for the importance of phages is mixed. Here, we critically review the theory and data exploring the role of phages in communities, identifying the conditions when phages are likely to be important drivers of community composition. At ec...
Source: Trends in Microbiology - April 11, 2024 Category: Microbiology Authors: Meaghan Castledine Angus Buckling Source Type: research
Critically evaluating the relative importance of phage in shaping microbial community composition
Trends Microbiol. 2024 Mar 20:S0966-842X(24)00057-X. doi: 10.1016/j.tim.2024.02.014. Online ahead of print.ABSTRACTThe ubiquity of bacteriophages (phages) and the major evolutionary and ecological impacts they can have on their microbial hosts has resulted in phages often cited as key drivers shaping microbial community composition (the relative abundances of species). However, the evidence for the importance of phages is mixed. Here, we critically review the theory and data exploring the role of phages in communities, identifying the conditions when phages are likely to be important drivers of community composition. At ec...
Source: Trends in Microbiology - April 11, 2024 Category: Microbiology Authors: Meaghan Castledine Angus Buckling Source Type: research
Rothia
Trends Microbiol. 2024 Apr 5:S0966-842X(24)00075-1. doi: 10.1016/j.tim.2024.03.009. Online ahead of print.NO ABSTRACTPMID:38580605 | DOI:10.1016/j.tim.2024.03.009 (Source: Trends in Microbiology)
Source: Trends in Microbiology - April 5, 2024 Category: Microbiology Authors: Shannon R West Allison B Suddaby Gina R Lewin Carolyn B Ibberson Source Type: research
Strategies for developing phages into novel antimicrobial tailocins
This article reviews three strategies for producing tailocins: disrupting the capsid-tail junction of phage particles, blocking capsid assembly during phage propagation, and creating headless phage particles synthetically. Particularly appealing is the production of tailocins through synthetic biology using phages with contractile tails as scaffolds to unlock the antimicrobial potential of tailocins.PMID:38580606 | DOI:10.1016/j.tim.2024.03.003 (Source: Trends in Microbiology)
Source: Trends in Microbiology - April 5, 2024 Category: Microbiology Authors: Cedric Woudstra Anders N ørgaard Sørensen Martine C Holst S ørensen Lone Br øndsted Source Type: research
Effectors and environment modulating rice blast disease: from understanding to effective control
Trends Microbiol. 2024 Apr 5:S0966-842X(24)00072-6. doi: 10.1016/j.tim.2024.03.006. Online ahead of print.ABSTRACTRice blast is a highly destructive crop disease that requires the interplay of three essential factors: the virulent blast fungus, the susceptible rice plant, and favorable environmental conditions. Although previous studies have focused mainly on the pathogen and rice, recent research has shed light on the molecular mechanisms by which the blast fungus and environmental conditions regulate host resistance and contribute to blast disease outbreaks. This review summarizes significant achievements in understandin...
Source: Trends in Microbiology - April 5, 2024 Category: Microbiology Authors: Yanjun Kou Huanbin Shi Jiehua Qiu Zeng Tao Wenming Wang Source Type: research
Current state and perspective of implementation of clinical metagenomics: Geneva ICCMg meeting report
Trends Microbiol. 2024 Apr 4:S0966-842X(24)00074-X. doi: 10.1016/j.tim.2024.03.008. Online ahead of print.NO ABSTRACTPMID:38580608 | DOI:10.1016/j.tim.2024.03.008 (Source: Trends in Microbiology)
Source: Trends in Microbiology - April 5, 2024 Category: Microbiology Authors: Etienne Rupp é Vladimir Lazarevic Jacques Schrenzel Source Type: research
Rothia
Trends Microbiol. 2024 Apr 5:S0966-842X(24)00075-1. doi: 10.1016/j.tim.2024.03.009. Online ahead of print.NO ABSTRACTPMID:38580605 | DOI:10.1016/j.tim.2024.03.009 (Source: Trends in Microbiology)
Source: Trends in Microbiology - April 5, 2024 Category: Microbiology Authors: Shannon R West Allison B Suddaby Gina R Lewin Carolyn B Ibberson Source Type: research
Strategies for developing phages into novel antimicrobial tailocins
This article reviews three strategies for producing tailocins: disrupting the capsid-tail junction of phage particles, blocking capsid assembly during phage propagation, and creating headless phage particles synthetically. Particularly appealing is the production of tailocins through synthetic biology using phages with contractile tails as scaffolds to unlock the antimicrobial potential of tailocins.PMID:38580606 | DOI:10.1016/j.tim.2024.03.003 (Source: Trends in Microbiology)
Source: Trends in Microbiology - April 5, 2024 Category: Microbiology Authors: Cedric Woudstra Anders N ørgaard Sørensen Martine C Holst S ørensen Lone Br øndsted Source Type: research
Effectors and environment modulating rice blast disease: from understanding to effective control
Trends Microbiol. 2024 Apr 5:S0966-842X(24)00072-6. doi: 10.1016/j.tim.2024.03.006. Online ahead of print.ABSTRACTRice blast is a highly destructive crop disease that requires the interplay of three essential factors: the virulent blast fungus, the susceptible rice plant, and favorable environmental conditions. Although previous studies have focused mainly on the pathogen and rice, recent research has shed light on the molecular mechanisms by which the blast fungus and environmental conditions regulate host resistance and contribute to blast disease outbreaks. This review summarizes significant achievements in understandin...
Source: Trends in Microbiology - April 5, 2024 Category: Microbiology Authors: Yanjun Kou Huanbin Shi Jiehua Qiu Zeng Tao Wenming Wang Source Type: research
Current state and perspective of implementation of clinical metagenomics: Geneva ICCMg meeting report
Trends Microbiol. 2024 Apr 4:S0966-842X(24)00074-X. doi: 10.1016/j.tim.2024.03.008. Online ahead of print.NO ABSTRACTPMID:38580608 | DOI:10.1016/j.tim.2024.03.008 (Source: Trends in Microbiology)
Source: Trends in Microbiology - April 5, 2024 Category: Microbiology Authors: Etienne Rupp é Vladimir Lazarevic Jacques Schrenzel Source Type: research
