Host factor KAP1 coordinates temporal control between transcription and replication
Trends Microbiol. 2023 Dec 29:S0966-842X(23)00338-4. doi: 10.1016/j.tim.2023.12.003. Online ahead of print.ABSTRACTTemporal control of transcription and replication is necessary for efficient Epstein-Barr virus reactivation. Xu et al. identified the KAP1/EA-D/ATM axis as a critical regulator of these processes. This discovery illuminates the collaboration between host and viral factors as an essential interaction for viral reactivation.PMID:38160193 | DOI:10.1016/j.tim.2023.12.003 (Source: Trends in Microbiology)
Source: Trends in Microbiology - December 30, 2023 Category: Microbiology Authors: Sarah Preston-Alp Italo Tempera Source Type: research

Microbial warfare: B. subtilis antagonizes E. coli biofilm formation
Trends Microbiol. 2023 Dec 28:S0966-842X(23)00355-4. doi: 10.1016/j.tim.2023.12.006. Online ahead of print.ABSTRACTBiofilm formation helps bacteria to survive environmental challenges. Biofilm development often involves multiple genetic pathways that can be regulated by external signals. Diego Serra and his team (Cordisco et al.) explore how Bacillus subtilis can antagonize Escherichia coli macrocolony biofilm formation via the metabolite bacillaene.PMID:38158310 | DOI:10.1016/j.tim.2023.12.006 (Source: Trends in Microbiology)
Source: Trends in Microbiology - December 29, 2023 Category: Microbiology Authors: Kailyn Jessel Matthew R Chapman Source Type: research

Cable bacteria: widespread filamentous electroactive microorganisms protecting environments
Trends Microbiol. 2023 Dec 26:S0966-842X(23)00336-0. doi: 10.1016/j.tim.2023.12.001. Online ahead of print.ABSTRACTCable bacteria have been identified and detected worldwide since their discovery in marine sediments in Aarhus Bay, Denmark. Their activity can account for the majority of oxygen consumption and sulfide depletion in sediments, and they induce sulfate accumulation, pH excursions, and the generation of electric fields. In addition, they can affect the fluxes of other elements such as calcium, iron, manganese, nitrogen, and phosphorous. Recent developments in our understanding of the impact of cable bacteria on e...
Source: Trends in Microbiology - December 27, 2023 Category: Microbiology Authors: Meijun Dong Lars Peter Nielsen Shan Yang Lasse Hyldgaard Klausen Meiying Xu Source Type: research

Cable bacteria: widespread filamentous electroactive microorganisms protecting environments
Trends Microbiol. 2023 Dec 26:S0966-842X(23)00336-0. doi: 10.1016/j.tim.2023.12.001. Online ahead of print.ABSTRACTCable bacteria have been identified and detected worldwide since their discovery in marine sediments in Aarhus Bay, Denmark. Their activity can account for the majority of oxygen consumption and sulfide depletion in sediments, and they induce sulfate accumulation, pH excursions, and the generation of electric fields. In addition, they can affect the fluxes of other elements such as calcium, iron, manganese, nitrogen, and phosphorous. Recent developments in our understanding of the impact of cable bacteria on e...
Source: Trends in Microbiology - December 27, 2023 Category: Microbiology Authors: Meijun Dong Lars Peter Nielsen Shan Yang Lasse Hyldgaard Klausen Meiying Xu Source Type: research

Cable bacteria: widespread filamentous electroactive microorganisms protecting environments
Trends Microbiol. 2023 Dec 26:S0966-842X(23)00336-0. doi: 10.1016/j.tim.2023.12.001. Online ahead of print.ABSTRACTCable bacteria have been identified and detected worldwide since their discovery in marine sediments in Aarhus Bay, Denmark. Their activity can account for the majority of oxygen consumption and sulfide depletion in sediments, and they induce sulfate accumulation, pH excursions, and the generation of electric fields. In addition, they can affect the fluxes of other elements such as calcium, iron, manganese, nitrogen, and phosphorous. Recent developments in our understanding of the impact of cable bacteria on e...
Source: Trends in Microbiology - December 27, 2023 Category: Microbiology Authors: Meijun Dong Lars Peter Nielsen Shan Yang Lasse Hyldgaard Klausen Meiying Xu Source Type: research

Cable bacteria: widespread filamentous electroactive microorganisms protecting environments
Trends Microbiol. 2023 Dec 26:S0966-842X(23)00336-0. doi: 10.1016/j.tim.2023.12.001. Online ahead of print.ABSTRACTCable bacteria have been identified and detected worldwide since their discovery in marine sediments in Aarhus Bay, Denmark. Their activity can account for the majority of oxygen consumption and sulfide depletion in sediments, and they induce sulfate accumulation, pH excursions, and the generation of electric fields. In addition, they can affect the fluxes of other elements such as calcium, iron, manganese, nitrogen, and phosphorous. Recent developments in our understanding of the impact of cable bacteria on e...
Source: Trends in Microbiology - December 27, 2023 Category: Microbiology Authors: Meijun Dong Lars Peter Nielsen Shan Yang Lasse Hyldgaard Klausen Meiying Xu Source Type: research

Cable bacteria: widespread filamentous electroactive microorganisms protecting environments
Trends Microbiol. 2023 Dec 26:S0966-842X(23)00336-0. doi: 10.1016/j.tim.2023.12.001. Online ahead of print.ABSTRACTCable bacteria have been identified and detected worldwide since their discovery in marine sediments in Aarhus Bay, Denmark. Their activity can account for the majority of oxygen consumption and sulfide depletion in sediments, and they induce sulfate accumulation, pH excursions, and the generation of electric fields. In addition, they can affect the fluxes of other elements such as calcium, iron, manganese, nitrogen, and phosphorous. Recent developments in our understanding of the impact of cable bacteria on e...
Source: Trends in Microbiology - December 27, 2023 Category: Microbiology Authors: Meijun Dong Lars Peter Nielsen Shan Yang Lasse Hyldgaard Klausen Meiying Xu Source Type: research

Diagnosing arthropod-borne flaviviruses: non-structural protein 1 (NS1) as a biomarker
Trends Microbiol. 2023 Dec 21:S0966-842X(23)00334-7. doi: 10.1016/j.tim.2023.11.016. Online ahead of print.ABSTRACTIn recent decades, the presence of flaviviruses of concern for human health in Europe has drastically increased,exacerbated by the effects of climate change - which has allowed the vectors of these viruses to expand into new territories. Co-circulation of West Nile virus (WNV), Usutu virus (USUV), and tick-borne encephalitis virus (TBEV) represents a threat to the European continent, and this is further complicated by the difficulty of obtaining an early and discriminating diagnosis of infection. Moreover, the...
Source: Trends in Microbiology - December 22, 2023 Category: Microbiology Authors: Martina Ceconi Kevin K Ari ën Peter Delputte Source Type: research

Modeling nontuberculous mycobacterial infections in zebrafish
Trends Microbiol. 2023 Dec 21:S0966-842X(23)00329-3. doi: 10.1016/j.tim.2023.11.011. Online ahead of print.ABSTRACTThe incidence of infections due to nontuberculous mycobacteria (NTM) has increased rapidly in recent years, surpassing tuberculosis in developed countries. Due to inherent antimicrobial resistance, NTM infections are particularly difficult to treat with low cure rates. There is an urgent need to understand NTM pathogenesis and to develop novel therapeutic approaches for the treatment of NTM diseases. Zebrafish have emerged as an excellent animal model due to genetic amenability and optical transparency during ...
Source: Trends in Microbiology - December 22, 2023 Category: Microbiology Authors: Matt D Johansen Herman P Spaink Stefan H Oehlers Laurent Kremer Source Type: research

Diagnosing arthropod-borne flaviviruses: non-structural protein 1 (NS1) as a biomarker
Trends Microbiol. 2023 Dec 21:S0966-842X(23)00334-7. doi: 10.1016/j.tim.2023.11.016. Online ahead of print.ABSTRACTIn recent decades, the presence of flaviviruses of concern for human health in Europe has drastically increased,exacerbated by the effects of climate change - which has allowed the vectors of these viruses to expand into new territories. Co-circulation of West Nile virus (WNV), Usutu virus (USUV), and tick-borne encephalitis virus (TBEV) represents a threat to the European continent, and this is further complicated by the difficulty of obtaining an early and discriminating diagnosis of infection. Moreover, the...
Source: Trends in Microbiology - December 22, 2023 Category: Microbiology Authors: Martina Ceconi Kevin K Ari ën Peter Delputte Source Type: research

Modeling nontuberculous mycobacterial infections in zebrafish
Trends Microbiol. 2023 Dec 21:S0966-842X(23)00329-3. doi: 10.1016/j.tim.2023.11.011. Online ahead of print.ABSTRACTThe incidence of infections due to nontuberculous mycobacteria (NTM) has increased rapidly in recent years, surpassing tuberculosis in developed countries. Due to inherent antimicrobial resistance, NTM infections are particularly difficult to treat with low cure rates. There is an urgent need to understand NTM pathogenesis and to develop novel therapeutic approaches for the treatment of NTM diseases. Zebrafish have emerged as an excellent animal model due to genetic amenability and optical transparency during ...
Source: Trends in Microbiology - December 22, 2023 Category: Microbiology Authors: Matt D Johansen Herman P Spaink Stefan H Oehlers Laurent Kremer Source Type: research

Diagnosing arthropod-borne flaviviruses: non-structural protein 1 (NS1) as a biomarker
Trends Microbiol. 2023 Dec 21:S0966-842X(23)00334-7. doi: 10.1016/j.tim.2023.11.016. Online ahead of print.ABSTRACTIn recent decades, the presence of flaviviruses of concern for human health in Europe has drastically increased,exacerbated by the effects of climate change - which has allowed the vectors of these viruses to expand into new territories. Co-circulation of West Nile virus (WNV), Usutu virus (USUV), and tick-borne encephalitis virus (TBEV) represents a threat to the European continent, and this is further complicated by the difficulty of obtaining an early and discriminating diagnosis of infection. Moreover, the...
Source: Trends in Microbiology - December 22, 2023 Category: Microbiology Authors: Martina Ceconi Kevin K Ari ën Peter Delputte Source Type: research

Modeling nontuberculous mycobacterial infections in zebrafish
Trends Microbiol. 2023 Dec 21:S0966-842X(23)00329-3. doi: 10.1016/j.tim.2023.11.011. Online ahead of print.ABSTRACTThe incidence of infections due to nontuberculous mycobacteria (NTM) has increased rapidly in recent years, surpassing tuberculosis in developed countries. Due to inherent antimicrobial resistance, NTM infections are particularly difficult to treat with low cure rates. There is an urgent need to understand NTM pathogenesis and to develop novel therapeutic approaches for the treatment of NTM diseases. Zebrafish have emerged as an excellent animal model due to genetic amenability and optical transparency during ...
Source: Trends in Microbiology - December 22, 2023 Category: Microbiology Authors: Matt D Johansen Herman P Spaink Stefan H Oehlers Laurent Kremer Source Type: research

Diagnosing arthropod-borne flaviviruses: non-structural protein 1 (NS1) as a biomarker
Trends Microbiol. 2023 Dec 21:S0966-842X(23)00334-7. doi: 10.1016/j.tim.2023.11.016. Online ahead of print.ABSTRACTIn recent decades, the presence of flaviviruses of concern for human health in Europe has drastically increased,exacerbated by the effects of climate change - which has allowed the vectors of these viruses to expand into new territories. Co-circulation of West Nile virus (WNV), Usutu virus (USUV), and tick-borne encephalitis virus (TBEV) represents a threat to the European continent, and this is further complicated by the difficulty of obtaining an early and discriminating diagnosis of infection. Moreover, the...
Source: Trends in Microbiology - December 22, 2023 Category: Microbiology Authors: Martina Ceconi Kevin K Ari ën Peter Delputte Source Type: research

Modeling nontuberculous mycobacterial infections in zebrafish
Trends Microbiol. 2023 Dec 21:S0966-842X(23)00329-3. doi: 10.1016/j.tim.2023.11.011. Online ahead of print.ABSTRACTThe incidence of infections due to nontuberculous mycobacteria (NTM) has increased rapidly in recent years, surpassing tuberculosis in developed countries. Due to inherent antimicrobial resistance, NTM infections are particularly difficult to treat with low cure rates. There is an urgent need to understand NTM pathogenesis and to develop novel therapeutic approaches for the treatment of NTM diseases. Zebrafish have emerged as an excellent animal model due to genetic amenability and optical transparency during ...
Source: Trends in Microbiology - December 22, 2023 Category: Microbiology Authors: Matt D Johansen Herman P Spaink Stefan H Oehlers Laurent Kremer Source Type: research