Traits-based approach: leveraging genome size in plant-microbe interactions
Trends Microbiol. 2023 Nov 2:S0966-842X(23)00294-9. doi: 10.1016/j.tim.2023.10.004. Online ahead of print.ABSTRACTTrait-based approaches have gained growing interest in studying plant-microbe interactions. However, current traits normally considered (e.g., morphological, physiological, or chemical traits) are biased towards those showing large intraspecific variations, necessitating the identification of fewer plastic traits that differ between species. Here, we propose using genome size (the amount of DNA in the nucleus of a cell) as a suitable trait for studying plant-microbiome interactions due to its relatively stable ...
Source: Trends in Microbiology - November 4, 2023 Category: Microbiology Authors: Haiyang Zhang Hongwei Liu Xingguo Han Source Type: research

Traits-based approach: leveraging genome size in plant-microbe interactions
Trends Microbiol. 2023 Nov 2:S0966-842X(23)00294-9. doi: 10.1016/j.tim.2023.10.004. Online ahead of print.ABSTRACTTrait-based approaches have gained growing interest in studying plant-microbe interactions. However, current traits normally considered (e.g., morphological, physiological, or chemical traits) are biased towards those showing large intraspecific variations, necessitating the identification of fewer plastic traits that differ between species. Here, we propose using genome size (the amount of DNA in the nucleus of a cell) as a suitable trait for studying plant-microbiome interactions due to its relatively stable ...
Source: Trends in Microbiology - November 4, 2023 Category: Microbiology Authors: Haiyang Zhang Hongwei Liu Xingguo Han Source Type: research

Traits-based approach: leveraging genome size in plant-microbe interactions
Trends Microbiol. 2023 Nov 2:S0966-842X(23)00294-9. doi: 10.1016/j.tim.2023.10.004. Online ahead of print.ABSTRACTTrait-based approaches have gained growing interest in studying plant-microbe interactions. However, current traits normally considered (e.g., morphological, physiological, or chemical traits) are biased towards those showing large intraspecific variations, necessitating the identification of fewer plastic traits that differ between species. Here, we propose using genome size (the amount of DNA in the nucleus of a cell) as a suitable trait for studying plant-microbiome interactions due to its relatively stable ...
Source: Trends in Microbiology - November 4, 2023 Category: Microbiology Authors: Haiyang Zhang Hongwei Liu Xingguo Han Source Type: research

Targeting wheat fusarium head blight with mycovirus-mediated VIGS
Trends Microbiol. 2023 Oct 30:S0966-842X(23)00296-2. doi: 10.1016/j.tim.2023.10.007. Online ahead of print.ABSTRACTFusarium head blight (FHB) caused by Fusarium graminearum occurs in wheat (Triticum aestivum) and threatens food production worldwide. Wheat lacks broad, durable FHB resistance. However, Zhang et al. developed a mycovirus-based virus-induced gene-silencing system in F. graminearum, providing efficient biocontrol of this devastating fungal disease.PMID:37914620 | DOI:10.1016/j.tim.2023.10.007 (Source: Trends in Microbiology)
Source: Trends in Microbiology - November 1, 2023 Category: Microbiology Authors: Junqi Zhang Xuetao Shi Wende Liu Source Type: research

Targeting wheat fusarium head blight with mycovirus-mediated VIGS
Trends Microbiol. 2023 Oct 30:S0966-842X(23)00296-2. doi: 10.1016/j.tim.2023.10.007. Online ahead of print.ABSTRACTFusarium head blight (FHB) caused by Fusarium graminearum occurs in wheat (Triticum aestivum) and threatens food production worldwide. Wheat lacks broad, durable FHB resistance. However, Zhang et al. developed a mycovirus-based virus-induced gene-silencing system in F. graminearum, providing efficient biocontrol of this devastating fungal disease.PMID:37914620 | DOI:10.1016/j.tim.2023.10.007 (Source: Trends in Microbiology)
Source: Trends in Microbiology - November 1, 2023 Category: Microbiology Authors: Junqi Zhang Xuetao Shi Wende Liu Source Type: research

Targeting wheat fusarium head blight with mycovirus-mediated VIGS
Trends Microbiol. 2023 Oct 30:S0966-842X(23)00296-2. doi: 10.1016/j.tim.2023.10.007. Online ahead of print.ABSTRACTFusarium head blight (FHB) caused by Fusarium graminearum occurs in wheat (Triticum aestivum) and threatens food production worldwide. Wheat lacks broad, durable FHB resistance. However, Zhang et al. developed a mycovirus-based virus-induced gene-silencing system in F. graminearum, providing efficient biocontrol of this devastating fungal disease.PMID:37914620 | DOI:10.1016/j.tim.2023.10.007 (Source: Trends in Microbiology)
Source: Trends in Microbiology - November 1, 2023 Category: Microbiology Authors: Junqi Zhang Xuetao Shi Wende Liu Source Type: research

Structure and molecular mechanism of bacterial transcription activation
Trends Microbiol. 2023 Oct 28:S0966-842X(23)00290-1. doi: 10.1016/j.tim.2023.10.001. Online ahead of print.ABSTRACTTranscription activation is an important checkpoint of regulation of gene expression which occurs in response to different intracellular and extracellular signals. The key elements in this signal transduction process are transcription activators, which determine when and how gene expression is activated. Recent structural studies on a considerable number of new transcription activation complexes (TACs) revealed the remarkable mechanistic diversity of transcription activation mediated by different factors, nece...
Source: Trends in Microbiology - October 30, 2023 Category: Microbiology Authors: Dmytro Kompaniiets Dong Wang Yang Yang Yangbo Hu Bin Liu Source Type: research

Structure and molecular mechanism of bacterial transcription activation
Trends Microbiol. 2023 Oct 28:S0966-842X(23)00290-1. doi: 10.1016/j.tim.2023.10.001. Online ahead of print.ABSTRACTTranscription activation is an important checkpoint of regulation of gene expression which occurs in response to different intracellular and extracellular signals. The key elements in this signal transduction process are transcription activators, which determine when and how gene expression is activated. Recent structural studies on a considerable number of new transcription activation complexes (TACs) revealed the remarkable mechanistic diversity of transcription activation mediated by different factors, nece...
Source: Trends in Microbiology - October 30, 2023 Category: Microbiology Authors: Dmytro Kompaniiets Dong Wang Yang Yang Yangbo Hu Bin Liu Source Type: research

Structure and molecular mechanism of bacterial transcription activation
Trends Microbiol. 2023 Oct 28:S0966-842X(23)00290-1. doi: 10.1016/j.tim.2023.10.001. Online ahead of print.ABSTRACTTranscription activation is an important checkpoint of regulation of gene expression which occurs in response to different intracellular and extracellular signals. The key elements in this signal transduction process are transcription activators, which determine when and how gene expression is activated. Recent structural studies on a considerable number of new transcription activation complexes (TACs) revealed the remarkable mechanistic diversity of transcription activation mediated by different factors, nece...
Source: Trends in Microbiology - October 30, 2023 Category: Microbiology Authors: Dmytro Kompaniiets Dong Wang Yang Yang Yangbo Hu Bin Liu Source Type: research

Gonococcal PorB: a multifaceted modulator of host immune responses
Trends Microbiol. 2023 Oct 25:S0966-842X(23)00291-3. doi: 10.1016/j.tim.2023.10.002. Online ahead of print.ABSTRACTNeisseria gonorrhoeae is a human-specific pathogen responsible for the sexually transmitted infection, gonorrhoea. N. gonorrhoeae promotes its survival by manipulating both innate and adaptive immune responses. The most abundant gonococcal outer-membrane protein is PorB, an essential porin that facilitates ion exchange. Importantly, gonococcal PorB has several immunomodulatory properties. To subvert the innate immune response, PorB suppresses killing mechanisms of macrophages and neutrophils, and recruits nega...
Source: Trends in Microbiology - October 27, 2023 Category: Microbiology Authors: Rebekah A Jones Ann E Jerse Christoph M Tang Source Type: research

Gonococcal PorB: a multifaceted modulator of host immune responses
Trends Microbiol. 2023 Oct 25:S0966-842X(23)00291-3. doi: 10.1016/j.tim.2023.10.002. Online ahead of print.ABSTRACTNeisseria gonorrhoeae is a human-specific pathogen responsible for the sexually transmitted infection, gonorrhoea. N. gonorrhoeae promotes its survival by manipulating both innate and adaptive immune responses. The most abundant gonococcal outer-membrane protein is PorB, an essential porin that facilitates ion exchange. Importantly, gonococcal PorB has several immunomodulatory properties. To subvert the innate immune response, PorB suppresses killing mechanisms of macrophages and neutrophils, and recruits nega...
Source: Trends in Microbiology - October 27, 2023 Category: Microbiology Authors: Rebekah A Jones Ann E Jerse Christoph M Tang Source Type: research

Cellular rejuvenation to combat HIV-1-related neurocognitive impairment
Trends Microbiol. 2023 Oct 14:S0966-842X(23)00286-X. doi: 10.1016/j.tim.2023.09.011. Online ahead of print.ABSTRACTHIV-1-related neurocognitive impairment affects a significant proportion of people living with HIV, and accelerated brain aging has been implicated in its pathogenesis. This forum explores the application of cellular rejuvenation strategies to target molecular mechanisms of brain aging, promote neuronal health, and combat cognitive decline.PMID:37845134 | DOI:10.1016/j.tim.2023.09.011 (Source: Trends in Microbiology)
Source: Trends in Microbiology - October 16, 2023 Category: Microbiology Authors: Philipp N Ostermann Teresa H Evering Source Type: research

Cellular rejuvenation to combat HIV-1-related neurocognitive impairment
Trends Microbiol. 2023 Oct 14:S0966-842X(23)00286-X. doi: 10.1016/j.tim.2023.09.011. Online ahead of print.ABSTRACTHIV-1-related neurocognitive impairment affects a significant proportion of people living with HIV, and accelerated brain aging has been implicated in its pathogenesis. This forum explores the application of cellular rejuvenation strategies to target molecular mechanisms of brain aging, promote neuronal health, and combat cognitive decline.PMID:37845134 | DOI:10.1016/j.tim.2023.09.011 (Source: Trends in Microbiology)
Source: Trends in Microbiology - October 16, 2023 Category: Microbiology Authors: Philipp N Ostermann Teresa H Evering Source Type: research

Cellular rejuvenation to combat HIV-1-related neurocognitive impairment
Trends Microbiol. 2023 Oct 14:S0966-842X(23)00286-X. doi: 10.1016/j.tim.2023.09.011. Online ahead of print.ABSTRACTHIV-1-related neurocognitive impairment affects a significant proportion of people living with HIV, and accelerated brain aging has been implicated in its pathogenesis. This forum explores the application of cellular rejuvenation strategies to target molecular mechanisms of brain aging, promote neuronal health, and combat cognitive decline.PMID:37845134 | DOI:10.1016/j.tim.2023.09.011 (Source: Trends in Microbiology)
Source: Trends in Microbiology - October 16, 2023 Category: Microbiology Authors: Philipp N Ostermann Teresa H Evering Source Type: research

Cellular rejuvenation to combat HIV-1-related neurocognitive impairment
Trends Microbiol. 2023 Oct 14:S0966-842X(23)00286-X. doi: 10.1016/j.tim.2023.09.011. Online ahead of print.ABSTRACTHIV-1-related neurocognitive impairment affects a significant proportion of people living with HIV, and accelerated brain aging has been implicated in its pathogenesis. This forum explores the application of cellular rejuvenation strategies to target molecular mechanisms of brain aging, promote neuronal health, and combat cognitive decline.PMID:37845134 | DOI:10.1016/j.tim.2023.09.011 (Source: Trends in Microbiology)
Source: Trends in Microbiology - October 16, 2023 Category: Microbiology Authors: Philipp N Ostermann Teresa H Evering Source Type: research