The origin of plasma neutrophil gelatinase-associated lipocalin in cardiac surgery
Acute kidney injury (AKI) is common after heart surgery. Neutrophil gelatinase-associated lipocalin (NGAL) is produced in injured kidney. NGAL has been used as an early plasma biomarker for AKI in patients und... (Source: BMC Nephrology)
Source: BMC Nephrology - May 22, 2019 Category: Urology & Nephrology Authors: Arie Passov, Liisa Pet äjä, Marjut Pihlajoki, Ulla-Stina Salminen, Raili Suojaranta, Antti Vento, Sture Andersson, Ville Pettilä, Alexey Schramko and Eero Pesonen Tags: Research article Source Type: research

Ultrasonographic length of morphologically-normal kidneys in children presented to a premier tertiary healthcare setting of Sri Lanka
Accurate prediction of reference ranges of renal lengths facilitates clinical decision making. Currently a single renal-length-reference chart is used for both kidneys, which is solely based on the age of the ... (Source: BMC Nephrology)
Source: BMC Nephrology - May 22, 2019 Category: Urology & Nephrology Authors: W. D. Duminda, K. G. Pathirana, M. U. J. Fernando, R. A. N. K. K. Samarasinghe, W. D. H. A. Ananda, K. S. P. Silva, C. K. Dissanayake and P. K. B. Mahesh Tags: Research article Source Type: research

Transcriptome analysis of signaling pathways of human peritoneal mesothelial cells in response to different osmotic agents in a peritoneal dialysis solution
Glucose is a primary osmotic agent in peritoneal dialysis (PD) solutions, but its long-term use causes structural alteration of the peritoneal membrane (PM). Hyperbranched polyglycerol (HPG) is a promising alt... (Source: BMC Nephrology)
Source: BMC Nephrology - May 21, 2019 Category: Urology & Nephrology Authors: Bin Liu, Shijian Feng, Ghida Dairi, Qiunong Guan, Irina Chafeeva, Hao Wang, Richard Liggins, Gerald da Roza, Jayachandran N. Kizhakkedathu and Caigan Du Tags: Research article Source Type: research

Aeromonas sobria peritonitis in a peritoneal dialysis (PD) patient: a case report and review of the literature
Peritonitis is a common cause of catheter removal and mortality in the patient undergoing peritoneal dialysis (PD). Various pathogenic organisms have been identified as the etiology of PD-related peritonitis, ... (Source: BMC Nephrology)
Source: BMC Nephrology - May 20, 2019 Category: Urology & Nephrology Authors: Panai Song, Jun Deng, Tao Hou, Xiao Fu, Lei Zhang, Lin Sun and Yinghong Liu Tags: Case report Source Type: research

Racial differences in inflammation and outcomes of aging among kidney transplant candidates
Inflammation is more common among African Americans (AAs), and it is associated with frailty, poor physical performance, and mortality in community-dwelling older adults. Given the elevated inflammation levels... (Source: BMC Nephrology)
Source: BMC Nephrology - May 17, 2019 Category: Urology & Nephrology Authors: Prakriti Shrestha, Christine E. Haugen, Nadia M. Chu, Ashton Shaffer, Jacqueline Garonzik-Wang, Silas P. Norman, Jeremy D. Walston, Dorry L. Segev and Mara A. McAdams-DeMarco Tags: Research article Source Type: research

Temporal validation of the CT-PIRP prognostic model for mortality and renal replacement therapy initiation in chronic kidney disease patients
A classification tree model (CT-PIRP) was developed in 2013 to predict the annual renal function decline of patients with chronic kidney disease (CKD) participating in the PIRP (Progetto Insufficienza Renale P... (Source: BMC Nephrology)
Source: BMC Nephrology - May 17, 2019 Category: Urology & Nephrology Authors: Dino Gibertoni, Paola Rucci, Marcora Mandreoli, Mattia Corradini, Davide Martelli, Giorgia Russo, Elena Mancini and Antonio Santoro Tags: Research article Source Type: research

Interventional study to improve adherence to phosphate binder treatment in dialysis patients
Adherence to phosphate binder treatment is important to prevent high serum phosphate level in chronic dialysis patients. We therefore wanted to investigate patient knowledge, beliefs about and adherence to pho... (Source: BMC Nephrology)
Source: BMC Nephrology - May 17, 2019 Category: Urology & Nephrology Authors: Bodil Jahren Hjem ås, Katrine Bøvre, Liv Mathiesen, Jonas Christoffer Lindstrøm and Kathrin Bjerknes Tags: Research article Source Type: research

The effect of increased frequency of hemodialysis on vitamin C concentrations: an ancillary study of the randomized Frequent Hemodialysis Network (FHN) daily trial
Reports on vitamin C in HD patients have shown effects of vitamin C deficiency in association with scurvy symptoms. Dialyzability of water soluble vitamins is high, and substantial losses in those who are dial... (Source: BMC Nephrology)
Source: BMC Nephrology - May 17, 2019 Category: Urology & Nephrology Authors: Jochen G. Raimann, Samer R. Abbas, Li Liu, Brett Larive, Gerald Beck, Peter Kotanko, Nathan W. Levin and Garry Handelman Tags: Research article Source Type: research

The impact of immunosuppression on postoperative graft function after graft-unrelated surgery: a retrospective controlled cohort study
Physicians are faced with a growing number of patients after renal transplantation undergoing graft-unrelated surgery. So far, little is known about the postoperative restitution of graft function and the risk... (Source: BMC Nephrology)
Source: BMC Nephrology - May 16, 2019 Category: Urology & Nephrology Authors: Ann-Kathrin Lederer, Dominic Haffa, Philipp Felgendreff, Frank Makowiec, Stefan Fichtner-Feigl, Roman Huber and Lampros Kousoulas Tags: Research article Source Type: research

Patient characteristics and initiation of mineralocorticoid receptor antagonists in patients with chronic kidney disease in routine clinical practice in the US: a retrospective cohort study
Steroidal mineralocorticoid receptor antagonists (MRAs) are recommended for the treatment of heart failure (HF) and resistant hypertension, both common comorbidities in patients with diabetes and chronic kidne... (Source: BMC Nephrology)
Source: BMC Nephrology - May 16, 2019 Category: Urology & Nephrology Authors: Michael Blankenburg, Anne-Kathrin Fett, Seline Eisenring, Gabriele Haas and Alain Gay Tags: Research article Source Type: research

The association between six month intra-dialytic resistance training and muscle strength or physical performance in patients with maintenance hemodialysis: a multicenter retrospective observational study
Reduced muscle strength and physical performance are prevalent in patients of maintenance hemodialysis (MHD), and deleterious changes in these parameters are associated with increased mortality. (Source: BMC Nephrology)
Source: BMC Nephrology - May 16, 2019 Category: Urology & Nephrology Authors: Yoshifumi Moriyama, Masahiko Hara, Sae Aratani, Hideaki Ishikawa, Kenichi Kono and Masatake Tamaki Tags: Research article Source Type: research

Two novel homozygous mutations in NPHP1 lead to late onset end-stage renal disease: a case report of an adult nephronophthisis in a Chinese intermarriage family
Nephronophthisis (NPHP) is an autosomal recessive hereditary disease with highly variable clinical characteristics for which 20 genes (NPHP1 –20) have been identified. NPHP1 is the major subtype leading to pediatr... (Source: BMC Nephrology)
Source: BMC Nephrology - May 16, 2019 Category: Urology & Nephrology Authors: Yiting Wang, Feng Chen, Jiali Wang, Yingwang Zhao and Fang Liu Tags: Case report Source Type: research

The impact of systematic review of status 7 patients on the kidney transplant waitlist
Increased morbidity and mortality are well documented in Status 7(inactive list) patients. Delays in transplantation secondary to prolonged periods on inactive status also negatively impacts transplant outcome... (Source: BMC Nephrology)
Source: BMC Nephrology - May 16, 2019 Category: Urology & Nephrology Authors: Ashish Kataria, Madan Gowda, Brian Paul Lamphron, Kabir Jalal, Rocco C. Venuto and Aijaz A. Gundroo Tags: Technical advance Source Type: research

Kidney autotransplantation for the treatment of renal artery occlusion after endovascular aortic repair: a case report
Unintentional renal artery occlusion after endovascular aneurysm repair (EVAR) for abdominal aortic aneurysm remains one of the most unfavorable complications. Renal salvage options include percutaneous transl... (Source: BMC Nephrology)
Source: BMC Nephrology - May 14, 2019 Category: Urology & Nephrology Authors: Atsuko Uehara, Tomo Suzuki, Soichiro Hase, Hirofumi Sumi, Satoshi Hachisuka, Eisuke Fujimoto, Kouichirou Aida, Ryuto Nakazawa, Hideo Sasaki, Junki Koike, Tatsuya Chikaraishi, Yugo Shibagaki and Yuhji Marui Tags: Case report Source Type: research

Rituximab in relapsing and de novo MPO ANCA-associated vasculitis with severe renal involvement: a case series
Antineutrophil cytoplasmic antibody associated vasculitis (AAV) is a group of diseases associated in most cases with the presence of anti-neutrophil cytoplasmic antibodies (ANCAs). Rituximab- based remission i... (Source: BMC Nephrology)
Source: BMC Nephrology - May 14, 2019 Category: Urology & Nephrology Authors: L. Caroti, C. L. Cirami, L. Di Maria, A. Larti, P. Carta, E. Dervishi, S. Farsetti, A. Tsalouchos, L. Novelli and E. E. Minetti Tags: Research article Source Type: research

Association between quality of life and various aspects of intradialytic hypotension including patient-reported intradialytic symptom score
There is increasing awareness that, besides patient survival, Quality of Life (QOL) is a relevant outcome factor for patients who have a chronic disease. In haemodialysis (HD) patients, intradialytic hypotensi... (Source: BMC Nephrology)
Source: BMC Nephrology - May 14, 2019 Category: Urology & Nephrology Authors: Johanna Kuipers, Jurjen K. Oosterhuis, Wolter Paans, Wim P. Krijnen, Carlo A. J. M. Gaillard, Ralf Westerhuis and Casper F. M. Franssen Tags: Research article Source Type: research

Refractory hypercalcemia due to an ectopic mediastinal parathyroid gland in a hemodialysis patient: a case report
Hypercalcemia crisis is a complex disorder rarely induced by tertiary hyperparathyroidism, which clinically presents as nonsuppressible parathyroid hyperplasia with persistent increased PTH levels and hypercal... (Source: BMC Nephrology)
Source: BMC Nephrology - May 14, 2019 Category: Urology & Nephrology Authors: Yingjing Shen and Peipei Fei Tags: Case report Source Type: research

Partial nephrogenic diabetes insipidus associated with Castleman ’s disease
Nephrogenic diabetes insipidus (DI) secondary to a urinary tract obstruction is a rare condition. Herein, we report a case of partial nephrogenic DI due to obstructive uropathy in a patient with Castleman ’s di... (Source: BMC Nephrology)
Source: BMC Nephrology - May 14, 2019 Category: Urology & Nephrology Authors: Minah Kim, Hong Sang Choi, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim and Chang Seong Kim Tags: Case report Source Type: research

Pirfenidone prevents acute kidney injury in the rat
Pirfenidone is an orally active drug used for the treatment of idiopathic pulmonary fibrosis to slow loss of lung function; it acts mainly through an antifibrotic effect but also possesses antioxidant and anti... (Source: BMC Nephrology)
Source: BMC Nephrology - May 8, 2019 Category: Urology & Nephrology Authors: Ixchel Lima-Posada, Francesco Fontana, Rosalba P érez-Villalva, Nathan Berman-Parks and Norma A. Bobadilla Tags: Research article Source Type: research

Chronic kidney disease and HIV in the era of antiretroviral treatment: findings from a 10-year cohort study in a west African setting
It has been reported that people living with HIV in West Africa exhibited the highest risks for chronic kidney disease (CKD) in the world. Here, we aimed at determining the CKD frequency and changes in kidney ... (Source: BMC Nephrology)
Source: BMC Nephrology - May 7, 2019 Category: Urology & Nephrology Authors: Nongodo Firmin Kabor é, Armel Poda, Jacques Zoungrana, Ollo Da, Laura Ciaffi, Aoua Semdé, Issouf Yaméogo, Adrien B. Sawadogo, Eric Delaporte, Nicolas Meda, Sophie Limou and Amandine Cournil Tags: Research article Source Type: research

Daily hemodialysis practices in Australia/New Zealand and in France: a comparative cohort study
As patients on daily hemodialysis (DHD) have heterogeneous profiles, DHD benefit in terms of survival is still debated. The aim of this study was to compare DHD practices in France and in Australia and New Zea... (Source: BMC Nephrology)
Source: BMC Nephrology - May 7, 2019 Category: Urology & Nephrology Authors: Ad élaïde Pladys, Sahar Bayat, Cécile Couchoud, Cécile Vigneau and Stephen McDonald Tags: Research article Source Type: research

Haemolytic uraemic syndrome associated with non shiga toxin-producing Escherichia coli bacteraemia: a case report
Haemolytic uraemic syndrome (HUS) is a thrombotic microangiopathy (TMA) characterized by predominant renal involvement. Several types of HUS can be distinguished: the most frequent « typical » HUS, due to shig... (Source: BMC Nephrology)
Source: BMC Nephrology - May 7, 2019 Category: Urology & Nephrology Authors: St éphane Bally, Jacques Fourcade and Véronique Frémeaux-Bacchi Tags: Case report Source Type: research

Staphylococcus aureus colonization in hemodialysis patients: a prospective 25  months observational study
Dialysis patients are frequently exposed to Staphylococcus aureus due to stays in dialysis centers, hospitals or rest homes. The hemodialysis vascular access is a potential entry site for S. aureus, in particular... (Source: BMC Nephrology)
Source: BMC Nephrology - May 6, 2019 Category: Urology & Nephrology Authors: Matthias Scheuch, Sabrina Freiin von Rheinbaben, Antje Kabisch, Jonas Enge ßer, Susanne Ahrendt, Thomas Dabers, Christian Kohler, Silva Holtfreter, Barbara M. Bröker and Sylvia Stracke Tags: Research article Source Type: research

Glucocorticoid induced adrenal insufficiency is common in steroid treated glomerular diseases - proposed strategy for screening and management
Glucocorticoids (GCs) are frequently used to treat glomerular diseases but are associated with multiple adverse effects including hypothalamic-pituitary-adrenal axis inhibition that can lead to adrenal insuffi... (Source: BMC Nephrology)
Source: BMC Nephrology - May 6, 2019 Category: Urology & Nephrology Authors: Alvin H. K. Karangizi, May Al-Shaghana, Sarah Logan, Sherwin Criseno, Rachel Webster, Kristien Boelaert, Peter Hewins and Lorraine Harper Tags: Research article Source Type: research

The atrial uremic cardiomyopathy regression in patients after kidney transplantation – the prospective echocardiographic study
In patients with end stage renal disease (ESRD), left ventricular (LV) hypertrophy with impaired LV function, which is called uremic cardiomyopathy (UC) is often observed. The UC historically has been consider... (Source: BMC Nephrology)
Source: BMC Nephrology - May 2, 2019 Category: Urology & Nephrology Authors: Tomasz Zapolski, Jacek Furmaga, Andrzej P. Wysoki ński, Anna Wysocka, Sławomir Rudzki and Andrzej Jaroszyński Tags: Research article Source Type: research

Clinical practice guideline monitoring children and young people with, or at risk of developing autosomal dominant polycystic kidney disease (ADPKD)
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is thought to affect about 1 in 1000 people in the UK. ADPKD causes a progressive decline in kidney function, with kidney failure tending to occur in middle... (Source: BMC Nephrology)
Source: BMC Nephrology - April 30, 2019 Category: Urology & Nephrology Authors: Jan Dudley, Paul Winyard, Matko Marlais, Oliver Cuthell, Tess Harris, Jiehan Chong, John Sayer, Daniel P. Gale, Lucy Moore, Kay Turner, Sarah Burrows and Richard Sandford Tags: Guidelines Source Type: research

Evaluation of the efficacy of an interdialytic “ethanol 40% v/v - enoxaparin 1000 U/mL” lock solution to prevent tunnelled catheter infections in chronic hemodialysis patients: a multi-centre, randomized, single blind, parallel group study
Tunnelled dialysis catheter (TC) infections are a major health complication and are associated with increased antibiotic consumption, hospital stays, health costs and mortality. Experimental data provide evide... (Source: BMC Nephrology)
Source: BMC Nephrology - April 30, 2019 Category: Urology & Nephrology Authors: Julien Aniort, Aur élien Piraud, Mireille Adda, Bruno Perreira, Marc Bouiller, Jacques Fourcade, Abdallah Guerraoui, Emilie Kalbacher, Thierry Krumel, Hélène Leray Moragues, Damien Thibaudin, Carlos Gustavo Vela, Guillaume Vernin, Hugo Weclawiak, Lise Tags: Study protocol Source Type: research

High serum IgA/C3 ratio better predicts a diagnosis of IgA nephropathy among primary glomerular nephropathy patients with proteinuria  ≤ 1 g/d: an observational cross-sectional study
This study sought to explore the diagnostic value of the IgA/C3 ratio in IgAN among primary glome... (Source: BMC Nephrology)
Source: BMC Nephrology - April 30, 2019 Category: Urology & Nephrology Authors: Wen-yu Gong, Man Liu, Dan Luo, Fan-na Liu, Liang-hong Yin, Yuan-qing Li, Jun Zhang and Hui Peng Tags: Research article Source Type: research

Health related quality of life of dialysis patients in Malaysia: Haemodialysis versus continuous ambulatory peritoneal dialysis
Health related quality of life (HRQOL) is an important predictor of clinical outcomes for End Stage Renal Disease (ESRD) patients and to establish quality adjusted life years (QALYs) for economic evaluation st... (Source: BMC Nephrology)
Source: BMC Nephrology - April 30, 2019 Category: Urology & Nephrology Authors: Naren Kumar Surendra, Mohd Rizal Abdul Manaf, Lai Seong Hooi, Sunita Bavanandan, Fariz Safhan Mohamad Nor, Shahnaz Shah Firdaus Khan, Loke Meng Ong and Abdul Halim Abdul Gafor Tags: Research article Source Type: research

Transplantation and diabetes (Transdiab): a pilot randomised controlled trial of metformin in impaired glucose tolerance after kidney transplantation
Post transplantation diabetes mellitus (PTDM) is a common and serious complication after renal transplantation with significant morbidity and mortality. Metformin has proven benefits in the general population ... (Source: BMC Nephrology)
Source: BMC Nephrology - April 29, 2019 Category: Urology & Nephrology Authors: Basil Alnasrallah, Tze Liang Goh, Lai Wan Chan, Paul Manley and Helen Pilmore Tags: Research article Source Type: research

Health-related quality of life as predictor of mortality in end-stage renal disease patients: an observational study
Health-related quality of life (HRQoL) is an important component of patient-centered outcomes and a useful parameter for monitoring quality of care. We assessed HRQoL, its determinants, and associations with m... (Source: BMC Nephrology)
Source: BMC Nephrology - April 29, 2019 Category: Urology & Nephrology Authors: Ming Pei, Rute Aguiar, Agneta A. Pagels, Olof Heimb ürger, Peter Stenvinkel, Peter Bárány, Charlotte Medin, Stefan H. Jacobson, Britta Hylander, Bengt Lindholm and Abdul Rashid Qureshi Tags: Research article Source Type: research

Increased ENaC activity during kidney preservation in Wisconsin solution
The invention of an effective kidney preservation solution capable of prolonging harvested kidney viability is the core of kidney transplantation procedure. Researchers have been working on upgrading the prese... (Source: BMC Nephrology)
Source: BMC Nephrology - April 29, 2019 Category: Urology & Nephrology Authors: Sherif Khedr, Oleg Palygin, Tengis S. Pavlov, Gregory Blass, Vladislav Levchenko, Ammar Alsheikh, Michael W. Brands, Ashraf El-Meanawy and Alexander Staruschenko Tags: Research article Source Type: research

Evaluating the feasibility of a nurse-led self-management support intervention for kidney transplant recipients: a pilot study
To support effective self-management after kidney transplantation, a holistic nurse-led self-management support intervention was developed using the Intervention Mapping approach. The primary aim was to evalua... (Source: BMC Nephrology)
Source: BMC Nephrology - April 27, 2019 Category: Urology & Nephrology Authors: Janet M. J. Been-Dahmen, Denise K. Beck, Mari ëlle A. C. Peeters, Heleen van der Stege, Mirjam Tielen, Marleen C. van Buren, Erwin Ista, AnneLoes van Staa and Emma K. Massey Tags: Research article Source Type: research

Self-management interventions for chronic kidney disease: a systematic review and meta-analysis
Self-management intervention aims to facilitate an individual ’s ability to make lifestyle changes. The effectiveness of this intervention in non-dialysis patients with chronic kidney disease (CKD) is limited. ... (Source: BMC Nephrology)
Source: BMC Nephrology - April 26, 2019 Category: Urology & Nephrology Authors: Suyuan Peng, Jiawei He, Jiasheng Huang, Longwei Lun, Jiahao Zeng, Shan Zeng, La Zhang, Xusheng Liu and Yifan Wu Tags: Research article Source Type: research

Resistant hypertension and cardiovascular disease mortality in the US: results from the National Health and Nutrition Examination Survey (NHANES)
Apparent treatment-resistant hypertension (aTRH) is a common condition associated with risk of cardiovascular events. However, the risk of cardiovascular mortality associated with aTRH in the US population is ... (Source: BMC Nephrology)
Source: BMC Nephrology - April 25, 2019 Category: Urology & Nephrology Authors: Katerina R. Kaczmarski, Stephen M. Sozio, Jingsha Chen, Yingying Sang and Tariq Shafi Tags: Research article Source Type: research

Prophylactic anticoagulation in nephrotic syndrome prevents thromboembolic complications
An increased incidence of thromboembolic events (TE) are reported in nephrotic syndrome (NS) leading to recommendations for prophylactic anticoagulation (PAC). However, as no randomized clinical trial has esta... (Source: BMC Nephrology)
Source: BMC Nephrology - April 25, 2019 Category: Urology & Nephrology Authors: Sarah Kelddal, Karen Marie Nykj ær, Jon Waarst Gregersen and Henrik Birn Tags: Research article Source Type: research

Effects of Brazilian green propolis on proteinuria and renal function in patients with chronic kidney disease: a randomized, double-blind, placebo-controlled trial
Chronic kidney disease (CKD) is a public health problem worldwide, and proteinuria is a well-established marker of disease progression in CKD patients. Propolis, a natural resin produced by bees from plant mat... (Source: BMC Nephrology)
Source: BMC Nephrology - April 25, 2019 Category: Urology & Nephrology Authors: Marcelo Augusto Duarte Silveira, Fl ávio Teles, Andressa A. Berretta, Talita R. Sanches, Camila Eleutério Rodrigues, Antonio Carlos Seguro and Lúcia Andrade Tags: Research article Source Type: research

Meprin β metalloproteases associated with differential metabolite profiles in the plasma and urine of mice with type 1 diabetes and diabetic nephropathy
Meprin metalloproteases are abundantly expressed in the brush border membranes of kidney proximal tubules and small intestines. Meprins are also expressed in podocytes and leukocytes (monocytes and macrophages... (Source: BMC Nephrology)
Source: BMC Nephrology - April 25, 2019 Category: Urology & Nephrology Authors: Jessica Gooding, Lei Cao, Courtney Whitaker, Jean-Marie Mwiza, Mizpha Fernander, Faihaa Ahmed, Zach Acuff, Susan McRitchie, Susan Sumner and Elimelda Moige Ongeri Tags: Research article Source Type: research

Recruitment and participant baseline characteristics in the dialysis outcomes in those aged 65 years or older study
Despite an increasing number of older people commencing dialysis the impact of dialysis on their quality of life and survival, remains unclear. The Dialysis Outcomes in those aged over 65  years or older study ... (Source: BMC Nephrology)
Source: BMC Nephrology - April 23, 2019 Category: Urology & Nephrology Authors: Bronwen McNoe, John B. W. Schollum, Sarah Derrett, Mark R. Marshall, Andrew Henderson, Ari Samaranayaka and Robert J. Walker Tags: Research article Source Type: research

Modelling the long-term benefits of tolvaptan therapy on renal function decline in autosomal dominant polycystic kidney disease: an exploratory analysis using the ADPKD outcomes model
The short-term efficacy of tolvaptan in patients with autosomal dominant polycystic kidney disease (ADPKD) has been demonstrated across several phase 3 trials, while the ADPKD Outcomes Model (ADPKD-OM) represe... (Source: BMC Nephrology)
Source: BMC Nephrology - April 23, 2019 Category: Urology & Nephrology Authors: Hayley Bennett, Phil McEwan, Karina Hamilton and Karl O ’Reilly Tags: Research article Source Type: research

Associations of serum and dialysate electrolytes with QT interval and prolongation in incident hemodialysis: the Predictors of Arrhythmic and Cardiovascular Risk in End-Stage Renal Disease (PACE) study
Prolonged QT interval in hemodialysis patients may be associated with sudden cardiac death, however, few studies examined the longitudinal associations of modifiable factors such as serum and dialysate concent... (Source: BMC Nephrology)
Source: BMC Nephrology - April 18, 2019 Category: Urology & Nephrology Authors: Esther D. Kim, Jacqueline Watt, Larisa G. Tereshchenko, Bernard G. Jaar, Stephen M. Sozio, W. H. Linda Kao, Michelle M. Estrella and Rulan S. Parekh Tags: Research article Source Type: research

Long-term peritoneal dialysis followed by kidney transplantation for Takayasu arteritis: a case report
Takayasu arteritis (TA) is a chronic vasculitis of unknown etiology that primarily affects large vessels. Although renal involvement is frequent in TA, patients with TA undergoing renal replacement therapy, es... (Source: BMC Nephrology)
Source: BMC Nephrology - April 18, 2019 Category: Urology & Nephrology Authors: Akane Yanai, Kiyotaka Uchiyama and Yoshitaka Ishibashi Tags: Case report Source Type: research

Improving proteinuria screening with mailed smartphone urinalysis testing in previously unscreened patients with hypertension: a randomized controlled trial
Proteinuria screening is recommended for patients with hypertension to screen for kidney disease and identify those at elevated risk for cardiovascular disease. However, screening rates among hypertensive pati... (Source: BMC Nephrology)
Source: BMC Nephrology - April 18, 2019 Category: Urology & Nephrology Authors: Julia Leddy, Jamie A. Green, Christina Yule, Juliann Molecavage, Josef Coresh and Alex R. Chang Tags: Research article Source Type: research

NAV-KIDS2 trial: protocol for a multi-centre, staggered randomised controlled trial of a patient navigator intervention in children with chronic kidney disease
Chronic kidney disease (CKD) is a devastating illness associated with increased mortality, reduced quality of life, impaired growth, neurocognitive impairment and psychosocial maladjustment in children. There ... (Source: BMC Nephrology)
Source: BMC Nephrology - April 18, 2019 Category: Urology & Nephrology Authors: Anita van Zwieten, Patrina Caldwell, Kirsten Howard, Allison Tong, Jonathan C. Craig, Stephen Alexander, Martin Howell, Teixeira-Pinto Armando, Carmel Hawley, Shilpa Jesudason, Amanda Walker, Fiona Mackie, Sean Kennedy, Steve McTaggart, Hugh McCarthy, Sim Tags: Study protocol Source Type: research

S1PR2 antagonist ameliorate high glucose-induced fission and dysfunction of mitochondria in HRGECs via regulating ROCK1
Sphingosine-1-phosphate receptor 2 (S1PR2) is a G-protein-coupled receptor that regulates sphingosine-1-phosphate-triggered cellular response. However, the role of S1PR2 in diabetes-induced glomerular endothel... (Source: BMC Nephrology)
Source: BMC Nephrology - April 18, 2019 Category: Urology & Nephrology Authors: Wei Chen, Hong Xiang, Ruifang Chen, Jie Yang, Xiaoping Yang, Jianda Zhou, Hengdao Liu, Shaoli Zhao, Jie Xiao, Pan Chen, Alex F. Chen, Shuhua Chen and Hongwei Lu Tags: Research article Source Type: research

Association between prediabetes (defined by HbA1C, fasting plasma glucose, and impaired glucose tolerance) and the development of chronic kidney disease: a 9-year prospective cohort study
The aim of the present study was to investigate the clinical impact of prediabetes on the development of incident chronic kidney disease (CKD) in a Korean adult population, using data from the Korea Genome and... (Source: BMC Nephrology)
Source: BMC Nephrology - April 16, 2019 Category: Urology & Nephrology Authors: Gwang Sil Kim, Hyun Ho Oh, Sang Hyun Kim, Byung Ok Kim and Young Sup Byun Tags: Research article Source Type: research

Predictors of short-term successful discontinuation of continuous renal replacement therapy: results from a prospective multicentre study
Prediction of successful discontinuation of continuous renal replacement therapy (CRRT) might reduce complications of over- and under-treatment. The aim of this study was to identify renal and non-renal predic... (Source: BMC Nephrology)
Source: BMC Nephrology - April 15, 2019 Category: Urology & Nephrology Authors: Susanne Stads, K. Merijn Kant, Margriet F. C. de Jong, Wouter de Ruijter, Christa M. Cobbaert, Michiel G. H. Betjes, Diederik Gommers and Heleen M. Oudemans-van Straaten Tags: Research article Source Type: research

Novel homozygous OSGEP gene pathogenic variants in two unrelated patients with Galloway-Mowat syndrome: case report and review of the literature
Galloway-Mowat syndrome (GAMOS) is a rare autosomal recessive disorder characterized by early-onset nephrotic syndrome and microcephaly with brain anomalies. WDR73 pathogenic variants were described as the first ... (Source: BMC Nephrology)
Source: BMC Nephrology - April 11, 2019 Category: Urology & Nephrology Authors: Andrea Domingo-Gallego, M ónica Furlano, Marc Pybus, Daniel Barraca, Ana Belén Martínez, Emiliano Mora Muñoz, Roser Torra and Elisabet Ars Tags: Case report Source Type: research

miR-10b suppresses cell invasion and metastasis through targeting HOXA3 regulated by FAK/YAP signaling pathway in clear-cell renal cell carcinoma
MicroRNAs have been related to tumor progression in diverse human cancers including clear-cell renal cell carcinoma (ccRCC). Previous study has suggested the important regulation function of miR-10b in ccRCC. ... (Source: BMC Nephrology)
Source: BMC Nephrology - April 11, 2019 Category: Urology & Nephrology Authors: Cheng He, Zhi-Yong Chen, Yang Li, Zhong-Qing Yang, Feng Zeng, Yu Cui, Yao He, Jin-Bo Chen and He-Qun Chen Tags: Research article Source Type: research

Dialysate cell-free mitochondrial DNA fragments as a marker of intraperitoneal inflammation and peritoneal solute transport rate in peritoneal dialysis
Mitochondrial DNA (mtDNA) released into extracellular subsequent to cell injury and death can promote inflammation in patients and animal models. However, the effects of peritoneal dialysate cell-free mtDNA on... (Source: BMC Nephrology)
Source: BMC Nephrology - April 11, 2019 Category: Urology & Nephrology Authors: Xishao Xie, Junni Wang, Shilong Xiang, Zhimin Chen, Xiaohui Zhang and Jianghua Chen Tags: Research article Source Type: research