Heat-Killed < em > Enterococcus faecium < /em > KU22001 Having Effective Anti-Cancer Effects on HeLa Cell Lines at a Lower Temperature
In conclusion, these results suggest that KU22001 can be beneficial owing to the anti-cancer effects and production of functional materials, such as EPS.PMID:38494869 | DOI:10.4014/jmb.2310.10050 (Source: Journal of Microbiology and Biotechnology)
Source: Journal of Microbiology and Biotechnology - March 18, 2024 Category: Biotechnology Authors: Jun-Su Ha Na-Kyoung Lee Hyun-Dong Paik Source Type: research

Heat-Killed < em > Enterococcus faecium < /em > KU22001 Having Effective Anti-Cancer Effects on HeLa Cell Lines at a Lower Temperature
In conclusion, these results suggest that KU22001 can be beneficial owing to the anti-cancer effects and production of functional materials, such as EPS.PMID:38494869 | DOI:10.4014/jmb.2310.10050 (Source: Journal of Microbiology and Biotechnology)
Source: Journal of Microbiology and Biotechnology - March 18, 2024 Category: Biotechnology Authors: Jun-Su Ha Na-Kyoung Lee Hyun-Dong Paik Source Type: research

Heat-Killed < em > Enterococcus faecium < /em > KU22001 Having Effective Anti-Cancer Effects on HeLa Cell Lines at a Lower Temperature
In conclusion, these results suggest that KU22001 can be beneficial owing to the anti-cancer effects and production of functional materials, such as EPS.PMID:38494869 | DOI:10.4014/jmb.2310.10050 (Source: Journal of Microbiology and Biotechnology)
Source: Journal of Microbiology and Biotechnology - March 18, 2024 Category: Biotechnology Authors: Jun-Su Ha Na-Kyoung Lee Hyun-Dong Paik Source Type: research

Heat-Killed < em > Enterococcus faecium < /em > KU22001 Having Effective Anti-Cancer Effects on HeLa Cell Lines at a Lower Temperature
In conclusion, these results suggest that KU22001 can be beneficial owing to the anti-cancer effects and production of functional materials, such as EPS.PMID:38494869 | DOI:10.4014/jmb.2310.10050 (Source: Journal of Microbiology and Biotechnology)
Source: Journal of Microbiology and Biotechnology - March 18, 2024 Category: Biotechnology Authors: Jun-Su Ha Na-Kyoung Lee Hyun-Dong Paik Source Type: research

Heat-Killed < em > Enterococcus faecium < /em > KU22001 Having Effective Anti-Cancer Effects on HeLa Cell Lines at a Lower Temperature
In conclusion, these results suggest that KU22001 can be beneficial owing to the anti-cancer effects and production of functional materials, such as EPS.PMID:38494869 | DOI:10.4014/jmb.2310.10050 (Source: Journal of Microbiology and Biotechnology)
Source: Journal of Microbiology and Biotechnology - March 18, 2024 Category: Biotechnology Authors: Jun-Su Ha Na-Kyoung Lee Hyun-Dong Paik Source Type: research

Sortase-encoding genes, srtA and srtC, mediate Enterococcus faecalis OG1RF persistence in the Helicoverpa zea gastrointestinal tract
Enterococcus faecalis is a commensal and opportunistic pathogen in the gastrointestinal (GI) tract of mammals and insects. To investigate mechanisms of bacterial persistence in the gastrointestinal tract (GIT), we developed a non-destructive sampling model using Helicoverpa zea, a destructive agricultural pest, as host to study the role of bacterial sortase enzymes in mitigating persistence in the gastrointestinal tract. E. faecalis OG1RF ΔsrtA and E. faecalis OG1RF ΔsrtC, isogenic E. faecalis OG1RF sortase mutants grew similarly under planktonic growth conditions relative to a streptomycin-resistant E. faecalis OG1RFS W...
Source: Frontiers in Microbiology - March 18, 2024 Category: Microbiology Source Type: research

Antimicrobial Resistance Characteristics of Fecal Escherichia coli and Enterococcus Species in U.S. Goats: 2019 National Animal Health Monitoring System Enteric Study
Foodborne Pathogens and Disease, Ahead of Print. (Source: Foodborne Pathogens and Disease)
Source: Foodborne Pathogens and Disease - March 18, 2024 Category: Food Science Authors: Catherine A. Gensler Stephanie C. Hempstead Shivaramu Keelara Paula J. Fedorka-Cray Natalie J. Urie Alyson M. Wiedenheft Keira Stuart Katherine L. Marshall Megan E. Jacob Source Type: research

Mutasynthesis Generates Nine New Pyrroindomycins
Org. Biomol. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4OB00239C, PaperZhuhua Wu, Zhengxiang Xia, Zhijun Tang, Ji ’an Li, Wen Liu Pyrroindomycins (PYRs) represent the only spirotetramate natural products discovered in nature, which possess potent activities against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium. Their unique structure and impressive biological activities... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Organic and Biomolecular Chemistry)
Source: RSC - Organic and Biomolecular Chemistry - March 16, 2024 Category: Molecular Biology Authors: Zhuhua Wu Source Type: research

Bee chitosan nanoparticles loaded with apitoxin as a novel approach to eradication of common human bacterial, fungal pathogens and treating cancer
This study aimed to extract chitosan from the exoskeletons of dead bees and load it with bee venom (commercially available as Apitoxin [Api]). Then, the ionotropic gelation method would be used to form nanoparticles that could be a novel drug-delivery system that might eradicate eight common human pathogens (i.e., two fungal and six bacteria strains). It might also be used to treat the human colon cancer cell line (Caco2 ATCC ATP-37) and human liver cancer cell line (HepG2ATCC HB-8065) cancer cell lines. The x-ray diffraction (XRD), Fourier transform infrared (FTIR), and dynamic light scattering (DLS) properties, ζ-potent...
Source: Frontiers in Microbiology - March 15, 2024 Category: Microbiology Source Type: research

Intestinal microbiota and biliary system diseases
DiscussionThe existing research mostly focuses on exploring the mechanisms of bacteria targeting a single disease. Lacking comparison of multiple diseases and changes in bacteria during the disease process. We hope to provide biomarkers forearly diagnosis of biliary system diseases and provide new directions for the mechanism of intestinal microbiota in biliary diseases. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 15, 2024 Category: Microbiology Source Type: research

Prevalence and Molecular Characterization of Vancomycin Variable < em > Enterococcus faecium < /em > Isolated From Clinical Specimens
Ann Lab Med. 2024 Mar 13. doi: 10.3343/alm.2023.0430. Online ahead of print.ABSTRACTVancomycin variable Enterococcus (VVE) bacteria are phenotypically susceptible to vancomycin, but they harbor the vanA gene. We aimed to ascertain the prevalence of VVE among clinically isolated vancomycin-susceptible Enterococcus faecium (VSE) isolates, as well as elucidate the molecular characteristics of the vanA gene cluster within these isolates. Notably, we investigated the prevalence and structure of the vanA gene cluster of VVE. Between June 2021 and May 2022, we collected consecutive, non-duplicated vancomycin-susceptible Enterococ...
Source: Annals of Laboratory Medicine - March 13, 2024 Category: Laboratory Medicine Authors: In Young Yoo Joo An Kwon Miran Lee Seung-Hyun Jung Jung Ok Kim Sung Il Ha Yeon-Joon Park Source Type: research

Production and characterization of rhamnolipids by Pseudomonas aeruginosa isolated in the Amazon region, and potential antiviral, antitumor, and antimicrobial activity
Sci Rep. 2024 Mar 12;14(1):4629. doi: 10.1038/s41598-024-54828-w.ABSTRACTBiosurfactants encompass structurally and chemically diverse molecules with surface active properties, and a broad industrial deployment, including pharmaceuticals. The interest is growing mainly for the low toxicity, biodegradability, and production from renewable sources. In this work, the optimized biosurfactant production by Pseudomonas aeruginosa BM02, isolated from the soil of a mining area in the Brazilian Amazon region was assessed, in addition to its antiviral, antitumor, and antimicrobial activities. The optimal conditions for biosurfactant ...
Source: Herpes - March 13, 2024 Category: Infectious Diseases Authors: Sidnei Cerqueira Dos Santos Chayenna Ara újo Torquato Darlisson de Alexandria Santos Alexandre Orsato Karoline Leite Juliana Mara Serpeloni Roberta Losi-Guembarovski Erica Rom ão Pereira Andr é Luiz Dyna Mario Gabriel Lopes Barboza Matheus Hideki Ferna Source Type: research

Epidemiological insights into seasonal, sex ‑specific and age‑related distribution of bacterial pathogens in urinary tract infections
Exp Ther Med. 2024 Feb 14;27(4):140. doi: 10.3892/etm.2024.12428. eCollection 2024 Apr.ABSTRACTUrinary tract infections (UTIs) are prevalent and recurrent bacterial infections that affect individuals worldwide, posing a significant burden on healthcare systems. The present study aimed to explore the epidemiology of UTIs, investigating the seasonal, gender-specific and age-related bacterial pathogen distribution to guide clinical diagnosis. Data were retrospectively collected from electronic medical records and laboratory reports of 926 UTIs diagnosed in Fuding Hospital (Fujian University of Traditional Chinese Medicine, Fu...
Source: Experimental and Therapeutic Medicine - March 13, 2024 Category: General Medicine Authors: Zhi-Song Zhan Jing Shi Zu-Shun Zheng Xue-Xia Zhu Juan Chen Xin-Yi Zhou Shi-Yan Zhang Source Type: research

Prevalence and Molecular Characterization of Vancomycin Variable < em > Enterococcus faecium < /em > Isolated From Clinical Specimens
Ann Lab Med. 2024 Mar 13. doi: 10.3343/alm.2023.0430. Online ahead of print.ABSTRACTVancomycin variable Enterococcus (VVE) bacteria are phenotypically susceptible to vancomycin, but they harbor the vanA gene. We aimed to ascertain the prevalence of VVE among clinically isolated vancomycin-susceptible Enterococcus faecium (VSE) isolates, as well as elucidate the molecular characteristics of the vanA gene cluster within these isolates. Notably, we investigated the prevalence and structure of the vanA gene cluster of VVE. Between June 2021 and May 2022, we collected consecutive, non-duplicated vancomycin-susceptible Enterococ...
Source: Annals of Laboratory Medicine - March 13, 2024 Category: Laboratory Medicine Authors: In Young Yoo Joo An Kwon Miran Lee Seung-Hyun Jung Jung Ok Kim Sung Il Ha Yeon-Joon Park Source Type: research

Production and characterization of rhamnolipids by Pseudomonas aeruginosa isolated in the Amazon region, and potential antiviral, antitumor, and antimicrobial activity
Sci Rep. 2024 Mar 12;14(1):4629. doi: 10.1038/s41598-024-54828-w.ABSTRACTBiosurfactants encompass structurally and chemically diverse molecules with surface active properties, and a broad industrial deployment, including pharmaceuticals. The interest is growing mainly for the low toxicity, biodegradability, and production from renewable sources. In this work, the optimized biosurfactant production by Pseudomonas aeruginosa BM02, isolated from the soil of a mining area in the Brazilian Amazon region was assessed, in addition to its antiviral, antitumor, and antimicrobial activities. The optimal conditions for biosurfactant ...
Source: Herpes - March 13, 2024 Category: Infectious Diseases Authors: Sidnei Cerqueira Dos Santos Chayenna Ara újo Torquato Darlisson de Alexandria Santos Alexandre Orsato Karoline Leite Juliana Mara Serpeloni Roberta Losi-Guembarovski Erica Rom ão Pereira Andr é Luiz Dyna Mario Gabriel Lopes Barboza Matheus Hideki Ferna Source Type: research