Prevalence and Resistance Patterns of Urinary Tract Infection in Al-Madinah Al-Munawarah, Saudi Arabia: A Retrospective Study
CONCLUSION: This study reported UT mono-infection and poly-infection in Al-Madinah Al-Munawarah, Saudi Arabia, with a predominant representation from gram-negative bacteria, Enterobacteriaceae. Most of the UT microbial strains showed a highly resistant profile.PMID:38665033 | DOI:10.24976/Discov.Med.202436183.80 (Source: Discovery Medicine)
Source: Discovery Medicine - April 26, 2024 Category: Research Authors: Areej A Alhhazmi Rawan A Alhazmi Eilaf S Alahmadi Wafa M Almuallim Zainab I Aljurfi Mohammad A Alturkostani Source Type: research

Scutellaria baicalensis Georgi alleviates Clostridium difficile associated diarrhea and its modulatory effects on the gut microbiota
Fitoterapia. 2024 Apr 23:105973. doi: 10.1016/j.fitote.2024.105973. Online ahead of print.ABSTRACTThe growing incidence of Clostridium difficile associated diarrhea (CDAD) underscores the urgency for potent treatments. This research delves into the therapeutic potential of Scutellaria baicalensis Georgi (Lamiaceae) root (SR) in addressing CDAD and its influence on gut microbiota. Using a CDAD mouse model and fidaxomicin as a control, SR's impact was measured through diarrhea symptoms, colonic histopathology, and C. difficile toxin levels. Employing the PacBio platform, 16S rRNA full-length gene sequencing analyzed the gut ...
Source: Fitoterapia - April 25, 2024 Category: Biochemistry Authors: Ze-Wei Tang Cong-En Zhang Fu-Zhi Ma Yu-Tao Cui Rui-Han Ye Shi-Biao Pu Zhi-Jie Ma Source Type: research

Static Versus Articulating Spacer: Does Infectious Pathogen Type Affect Treatment Success?
CONCLUSION: The lack of a difference in failure-free survival and insufficient evidence of a difference in the association between spacer type and treatment failure by pathogen type suggests that infectious organism may not be an important consideration in the decision about spacer treatment type. Further studies should aim to elucidate which patient factors are the most influential in surgeon decision-making when choosing a spacer type in patients with PJI of the knee.Level of Evidence Level III, therapeutic study.PMID:38662933 | DOI:10.1097/CORR.0000000000003075 (Source: Clinical Orthopaedics and Related Research)
Source: Clinical Orthopaedics and Related Research - April 25, 2024 Category: Orthopaedics Authors: Caitlin Grant Jerry Chang Emily Poehlein Cynthia L Green Jessica Seidelman William Jiranek Source Type: research

Scutellaria baicalensis Georgi alleviates Clostridium difficile associated diarrhea and its modulatory effects on the gut microbiota
Fitoterapia. 2024 Apr 23:105973. doi: 10.1016/j.fitote.2024.105973. Online ahead of print.ABSTRACTThe growing incidence of Clostridium difficile associated diarrhea (CDAD) underscores the urgency for potent treatments. This research delves into the therapeutic potential of Scutellaria baicalensis Georgi (Lamiaceae) root (SR) in addressing CDAD and its influence on gut microbiota. Using a CDAD mouse model and fidaxomicin as a control, SR's impact was measured through diarrhea symptoms, colonic histopathology, and C. difficile toxin levels. Employing the PacBio platform, 16S rRNA full-length gene sequencing analyzed the gut ...
Source: Fitoterapia - April 25, 2024 Category: Biochemistry Authors: Ze-Wei Tang Cong-En Zhang Fu-Zhi Ma Yu-Tao Cui Rui-Han Ye Shi-Biao Pu Zhi-Jie Ma Source Type: research

Scutellaria baicalensis Georgi alleviates Clostridium difficile associated diarrhea and its modulatory effects on the gut microbiota
Fitoterapia. 2024 Apr 23:105973. doi: 10.1016/j.fitote.2024.105973. Online ahead of print.ABSTRACTThe growing incidence of Clostridium difficile associated diarrhea (CDAD) underscores the urgency for potent treatments. This research delves into the therapeutic potential of Scutellaria baicalensis Georgi (Lamiaceae) root (SR) in addressing CDAD and its influence on gut microbiota. Using a CDAD mouse model and fidaxomicin as a control, SR's impact was measured through diarrhea symptoms, colonic histopathology, and C. difficile toxin levels. Employing the PacBio platform, 16S rRNA full-length gene sequencing analyzed the gut ...
Source: Fitoterapia - April 25, 2024 Category: Biochemistry Authors: Ze-Wei Tang Cong-En Zhang Fu-Zhi Ma Yu-Tao Cui Rui-Han Ye Shi-Biao Pu Zhi-Jie Ma Source Type: research

Scutellaria baicalensis Georgi alleviates Clostridium difficile associated diarrhea and its modulatory effects on the gut microbiota
Fitoterapia. 2024 Apr 23:105973. doi: 10.1016/j.fitote.2024.105973. Online ahead of print.ABSTRACTThe growing incidence of Clostridium difficile associated diarrhea (CDAD) underscores the urgency for potent treatments. This research delves into the therapeutic potential of Scutellaria baicalensis Georgi (Lamiaceae) root (SR) in addressing CDAD and its influence on gut microbiota. Using a CDAD mouse model and fidaxomicin as a control, SR's impact was measured through diarrhea symptoms, colonic histopathology, and C. difficile toxin levels. Employing the PacBio platform, 16S rRNA full-length gene sequencing analyzed the gut ...
Source: Fitoterapia - April 25, 2024 Category: Biochemistry Authors: Ze-Wei Tang Cong-En Zhang Fu-Zhi Ma Yu-Tao Cui Rui-Han Ye Shi-Biao Pu Zhi-Jie Ma Source Type: research

Diacetylcurcumin: a novel strategy against Enterococcus faecalis biofilm in root canal disinfection
Future Microbiology, Ahead of Print. (Source: Future Microbiology)
Source: Future Microbiology - April 25, 2024 Category: Microbiology Authors: Vanessa de Souza Carlos Roberto Polaquini Graciele Ribeiro de Moraes Arthur Rodrigues Oliveira Braga Priscila Vieira da Silva Diego Rom ário da Silva Francisco Ricardo Ribeiro Lima Lu ís Octávio Regasini Janaina de C ássia Orlandi Sardi Source Type: research

Reduction of product composition variability using pooled microbiome ecosystem therapy and consequence in two infectious murine models
In this study, we compared the metagenomic profile of pooled products to corresponding single donor-derived products. We demonstrated that pooled products are more homogeneous, diverse, and enriched in beneficial bacteria known to produce anti-inflammatory short chain fatty acids compared to single donor-derived products. We then evaluated pooled products' efficacy compared to corresponding single donor-derived products in Salmonella and C. difficile infectious mouse models. We were able to demonstrate that pooled products decreased pathogenicity by inducing a structural change in the intestinal microbiota composition. Sin...
Source: Cancer Control - April 23, 2024 Category: Cancer & Oncology Authors: Julie Reygner Johanne Delannoy Marie-Th érèse Barba-Goudiaby Cyrielle Gasc Beno ît Levast Enora Gaschet Laurent Ferraris St éphane Paul Nathalie Kapel Anne-Judith Waligora-Dupriet Frederic Barbut Muriel Thomas Carole Schwintner Bastien Laperrousaz Nat Source Type: research