Epidemiological insights into seasonal, sex ‑specific and age‑related distribution of bacterial pathogens in urinary tract infections
Exp Ther Med. 2024 Feb 14;27(4):140. doi: 10.3892/etm.2024.12428. eCollection 2024 Apr.ABSTRACTUrinary tract infections (UTIs) are prevalent and recurrent bacterial infections that affect individuals worldwide, posing a significant burden on healthcare systems. The present study aimed to explore the epidemiology of UTIs, investigating the seasonal, gender-specific and age-related bacterial pathogen distribution to guide clinical diagnosis. Data were retrospectively collected from electronic medical records and laboratory reports of 926 UTIs diagnosed in Fuding Hospital (Fujian University of Traditional Chinese Medicine, Fu...
Source: Experimental and Therapeutic Medicine - March 13, 2024 Category: General Medicine Authors: Zhi-Song Zhan Jing Shi Zu-Shun Zheng Xue-Xia Zhu Juan Chen Xin-Yi Zhou Shi-Yan Zhang Source Type: research
Panaxynol improves crypt and mucosal architecture, suppresses colitis-enriched microbes, and alters the immune response to mitigate colitis
This study builds on our initial data, which showed that panaxynol - a novel, potent, bioavailable compound found in American ginseng - can suppress disease severity in murine colitis. Here we explore the underlying mechanisms by which panaxynol improves both chronic and acute murine colitis. 14-week-old C57BL/6 female mice were either given 3 rounds of dextran sulfate sodium (DSS) in drinking water to induce chronic colitis or 1 round to induce acute colitis. Vehicle or panaxynol (2.5 mg/kg) was administered via oral gavage 3x/week for the study duration. Consistent with our previous findings, panaxynol significantly (p&l...
Source: Am J Physiol Gastroi... - March 12, 2024 Category: Gastroenterology Authors: Brooke M Bullard Sierra J McDonald Thomas D Cardaci Brandon N VanderVeen Ahmed D Mohammed Jason L Kubinak Joseph F Pierre Ioulia Chatzistamou Daping Fan Lorne J Hofseth E Angela Murphy Source Type: research
Panaxynol improves crypt and mucosal architecture, suppresses colitis-enriched microbes, and alters the immune response to mitigate colitis
This study builds on our initial data, which showed that panaxynol - a novel, potent, bioavailable compound found in American ginseng - can suppress disease severity in murine colitis. Here we explore the underlying mechanisms by which panaxynol improves both chronic and acute murine colitis. 14-week-old C57BL/6 female mice were either given 3 rounds of dextran sulfate sodium (DSS) in drinking water to induce chronic colitis or 1 round to induce acute colitis. Vehicle or panaxynol (2.5 mg/kg) was administered via oral gavage 3x/week for the study duration. Consistent with our previous findings, panaxynol significantly (p&l...
Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - March 12, 2024 Category: Physiology Authors: Brooke M Bullard Sierra J McDonald Thomas D Cardaci Brandon N VanderVeen Ahmed D Mohammed Jason L Kubinak Joseph F Pierre Ioulia Chatzistamou Daping Fan Lorne J Hofseth E Angela Murphy Source Type: research
Panaxynol improves crypt and mucosal architecture, suppresses colitis-enriched microbes, and alters the immune response to mitigate colitis
This study builds on our initial data, which showed that panaxynol - a novel, potent, bioavailable compound found in American ginseng - can suppress disease severity in murine colitis. Here we explore the underlying mechanisms by which panaxynol improves both chronic and acute murine colitis. 14-week-old C57BL/6 female mice were either given 3 rounds of dextran sulfate sodium (DSS) in drinking water to induce chronic colitis or 1 round to induce acute colitis. Vehicle or panaxynol (2.5 mg/kg) was administered via oral gavage 3x/week for the study duration. Consistent with our previous findings, panaxynol significantly (p&l...
Source: Am J Physiol Gastroi... - March 12, 2024 Category: Gastroenterology Authors: Brooke M Bullard Sierra J McDonald Thomas D Cardaci Brandon N VanderVeen Ahmed D Mohammed Jason L Kubinak Joseph F Pierre Ioulia Chatzistamou Daping Fan Lorne J Hofseth E Angela Murphy Source Type: research
Panaxynol improves crypt and mucosal architecture, suppresses colitis-enriched microbes, and alters the immune response to mitigate colitis
This study builds on our initial data, which showed that panaxynol - a novel, potent, bioavailable compound found in American ginseng - can suppress disease severity in murine colitis. Here we explore the underlying mechanisms by which panaxynol improves both chronic and acute murine colitis. 14-week-old C57BL/6 female mice were either given 3 rounds of dextran sulfate sodium (DSS) in drinking water to induce chronic colitis or 1 round to induce acute colitis. Vehicle or panaxynol (2.5 mg/kg) was administered via oral gavage 3x/week for the study duration. Consistent with our previous findings, panaxynol significantly (p&l...
Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - March 12, 2024 Category: Physiology Authors: Brooke M Bullard Sierra J McDonald Thomas D Cardaci Brandon N VanderVeen Ahmed D Mohammed Jason L Kubinak Joseph F Pierre Ioulia Chatzistamou Daping Fan Lorne J Hofseth E Angela Murphy Source Type: research
Panaxynol improves crypt and mucosal architecture, suppresses colitis-enriched microbes, and alters the immune response to mitigate colitis
This study builds on our initial data, which showed that panaxynol - a novel, potent, bioavailable compound found in American ginseng - can suppress disease severity in murine colitis. Here we explore the underlying mechanisms by which panaxynol improves both chronic and acute murine colitis. 14-week-old C57BL/6 female mice were either given 3 rounds of dextran sulfate sodium (DSS) in drinking water to induce chronic colitis or 1 round to induce acute colitis. Vehicle or panaxynol (2.5 mg/kg) was administered via oral gavage 3x/week for the study duration. Consistent with our previous findings, panaxynol significantly (p&l...
Source: Am J Physiol Gastroi... - March 12, 2024 Category: Gastroenterology Authors: Brooke M Bullard Sierra J McDonald Thomas D Cardaci Brandon N VanderVeen Ahmed D Mohammed Jason L Kubinak Joseph F Pierre Ioulia Chatzistamou Daping Fan Lorne J Hofseth E Angela Murphy Source Type: research
Panaxynol improves crypt and mucosal architecture, suppresses colitis-enriched microbes, and alters the immune response to mitigate colitis
This study builds on our initial data, which showed that panaxynol - a novel, potent, bioavailable compound found in American ginseng - can suppress disease severity in murine colitis. Here we explore the underlying mechanisms by which panaxynol improves both chronic and acute murine colitis. 14-week-old C57BL/6 female mice were either given 3 rounds of dextran sulfate sodium (DSS) in drinking water to induce chronic colitis or 1 round to induce acute colitis. Vehicle or panaxynol (2.5 mg/kg) was administered via oral gavage 3x/week for the study duration. Consistent with our previous findings, panaxynol significantly (p&l...
Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - March 12, 2024 Category: Physiology Authors: Brooke M Bullard Sierra J McDonald Thomas D Cardaci Brandon N VanderVeen Ahmed D Mohammed Jason L Kubinak Joseph F Pierre Ioulia Chatzistamou Daping Fan Lorne J Hofseth E Angela Murphy Source Type: research
Panaxynol improves crypt and mucosal architecture, suppresses colitis-enriched microbes, and alters the immune response to mitigate colitis
This study builds on our initial data, which showed that panaxynol - a novel, potent, bioavailable compound found in American ginseng - can suppress disease severity in murine colitis. Here we explore the underlying mechanisms by which panaxynol improves both chronic and acute murine colitis. 14-week-old C57BL/6 female mice were either given 3 rounds of dextran sulfate sodium (DSS) in drinking water to induce chronic colitis or 1 round to induce acute colitis. Vehicle or panaxynol (2.5 mg/kg) was administered via oral gavage 3x/week for the study duration. Consistent with our previous findings, panaxynol significantly (p&l...
Source: Am J Physiol Gastroi... - March 12, 2024 Category: Gastroenterology Authors: Brooke M Bullard Sierra J McDonald Thomas D Cardaci Brandon N VanderVeen Ahmed D Mohammed Jason L Kubinak Joseph F Pierre Ioulia Chatzistamou Daping Fan Lorne J Hofseth E Angela Murphy Source Type: research
Panaxynol improves crypt and mucosal architecture, suppresses colitis-enriched microbes, and alters the immune response to mitigate colitis
This study builds on our initial data, which showed that panaxynol - a novel, potent, bioavailable compound found in American ginseng - can suppress disease severity in murine colitis. Here we explore the underlying mechanisms by which panaxynol improves both chronic and acute murine colitis. 14-week-old C57BL/6 female mice were either given 3 rounds of dextran sulfate sodium (DSS) in drinking water to induce chronic colitis or 1 round to induce acute colitis. Vehicle or panaxynol (2.5 mg/kg) was administered via oral gavage 3x/week for the study duration. Consistent with our previous findings, panaxynol significantly (p&l...
Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - March 12, 2024 Category: Physiology Authors: Brooke M Bullard Sierra J McDonald Thomas D Cardaci Brandon N VanderVeen Ahmed D Mohammed Jason L Kubinak Joseph F Pierre Ioulia Chatzistamou Daping Fan Lorne J Hofseth E Angela Murphy Source Type: research
Panaxynol improves crypt and mucosal architecture, suppresses colitis-enriched microbes, and alters the immune response to mitigate colitis
This study builds on our initial data, which showed that panaxynol - a novel, potent, bioavailable compound found in American ginseng - can suppress disease severity in murine colitis. Here we explore the underlying mechanisms by which panaxynol improves both chronic and acute murine colitis. 14-week-old C57BL/6 female mice were either given 3 rounds of dextran sulfate sodium (DSS) in drinking water to induce chronic colitis or 1 round to induce acute colitis. Vehicle or panaxynol (2.5 mg/kg) was administered via oral gavage 3x/week for the study duration. Consistent with our previous findings, panaxynol significantly (p&l...
Source: Am J Physiol Gastroi... - March 12, 2024 Category: Gastroenterology Authors: Brooke M Bullard Sierra J McDonald Thomas D Cardaci Brandon N VanderVeen Ahmed D Mohammed Jason L Kubinak Joseph F Pierre Ioulia Chatzistamou Daping Fan Lorne J Hofseth E Angela Murphy Source Type: research
