Fully Characterized Effective Bacteriophages Specific against Antibiotic-Resistant < em > Enterococcus faecalis < /em > , the Causative Agent of Dental Abscess
Conclusions: The findings highlight the promise of phage therapy in dental medicine, offering a novel approach to combating antibiotic resistance and enhancing patient outcomes. Further research and clinical trials will be essential to fully understand the therapeutic potential and safety profile of these bacteriophages in human populations.PMID:38541227 | PMC:PMC10972216 | DOI:10.3390/medicina60030501 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Asmaa Ramadan Mohamed O Abdel-Monem Noha K El-Dougdoug Alsayed E Mekky Shymaa A Elaskary Abdulaziz A Al-Askar Shimaa A Metwally Ahmed F El-Sayed Gehad AbdElgayed Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Fully Characterized Effective Bacteriophages Specific against Antibiotic-Resistant < em > Enterococcus faecalis < /em > , the Causative Agent of Dental Abscess
Conclusions: The findings highlight the promise of phage therapy in dental medicine, offering a novel approach to combating antibiotic resistance and enhancing patient outcomes. Further research and clinical trials will be essential to fully understand the therapeutic potential and safety profile of these bacteriophages in human populations.PMID:38541227 | PMC:PMC10972216 | DOI:10.3390/medicina60030501 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Asmaa Ramadan Mohamed O Abdel-Monem Noha K El-Dougdoug Alsayed E Mekky Shymaa A Elaskary Abdulaziz A Al-Askar Shimaa A Metwally Ahmed F El-Sayed Gehad AbdElgayed Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Fully Characterized Effective Bacteriophages Specific against Antibiotic-Resistant < em > Enterococcus faecalis < /em > , the Causative Agent of Dental Abscess
Conclusions: The findings highlight the promise of phage therapy in dental medicine, offering a novel approach to combating antibiotic resistance and enhancing patient outcomes. Further research and clinical trials will be essential to fully understand the therapeutic potential and safety profile of these bacteriophages in human populations.PMID:38541227 | PMC:PMC10972216 | DOI:10.3390/medicina60030501 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Asmaa Ramadan Mohamed O Abdel-Monem Noha K El-Dougdoug Alsayed E Mekky Shymaa A Elaskary Abdulaziz A Al-Askar Shimaa A Metwally Ahmed F El-Sayed Gehad AbdElgayed Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Fully Characterized Effective Bacteriophages Specific against Antibiotic-Resistant < em > Enterococcus faecalis < /em > , the Causative Agent of Dental Abscess
Conclusions: The findings highlight the promise of phage therapy in dental medicine, offering a novel approach to combating antibiotic resistance and enhancing patient outcomes. Further research and clinical trials will be essential to fully understand the therapeutic potential and safety profile of these bacteriophages in human populations.PMID:38541227 | PMC:PMC10972216 | DOI:10.3390/medicina60030501 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Asmaa Ramadan Mohamed O Abdel-Monem Noha K El-Dougdoug Alsayed E Mekky Shymaa A Elaskary Abdulaziz A Al-Askar Shimaa A Metwally Ahmed F El-Sayed Gehad AbdElgayed Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Fully Characterized Effective Bacteriophages Specific against Antibiotic-Resistant < em > Enterococcus faecalis < /em > , the Causative Agent of Dental Abscess
Conclusions: The findings highlight the promise of phage therapy in dental medicine, offering a novel approach to combating antibiotic resistance and enhancing patient outcomes. Further research and clinical trials will be essential to fully understand the therapeutic potential and safety profile of these bacteriophages in human populations.PMID:38541227 | PMC:PMC10972216 | DOI:10.3390/medicina60030501 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Asmaa Ramadan Mohamed O Abdel-Monem Noha K El-Dougdoug Alsayed E Mekky Shymaa A Elaskary Abdulaziz A Al-Askar Shimaa A Metwally Ahmed F El-Sayed Gehad AbdElgayed Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Fully Characterized Effective Bacteriophages Specific against Antibiotic-Resistant < em > Enterococcus faecalis < /em > , the Causative Agent of Dental Abscess
Conclusions: The findings highlight the promise of phage therapy in dental medicine, offering a novel approach to combating antibiotic resistance and enhancing patient outcomes. Further research and clinical trials will be essential to fully understand the therapeutic potential and safety profile of these bacteriophages in human populations.PMID:38541227 | PMC:PMC10972216 | DOI:10.3390/medicina60030501 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Asmaa Ramadan Mohamed O Abdel-Monem Noha K El-Dougdoug Alsayed E Mekky Shymaa A Elaskary Abdulaziz A Al-Askar Shimaa A Metwally Ahmed F El-Sayed Gehad AbdElgayed Ebrahim Saied Mohamed Khedr Source Type: research

Genetic analysis of vancomycin-variable Enterococcus faecium clinical isolates in Italy
ConclusionWe highlight the importance of VVE transition to VRE under vancomycin therapy resulting in a potential failure treatment. We also report the first-time identification of VVE-S isolatespstS-null belonging to ST1478. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - March 27, 2024 Category: Microbiology Source Type: research

Detection of < em > Enterococcus cecorum < /em > to identify persistently contaminated locations using faecal and environmental samples in broiler houses of clinically healthy flocks
Avian Pathol. 2024 Mar 25:1-20. doi: 10.1080/03079457.2024.2334682. Online ahead of print.ABSTRACTWorldwide outbreaks make infections with pathogenic strains of Enterococcus cecorum (EC) one of the most important diseases in the broiler industry. Although research has increased knowledge about the pathogen, the transmission is not fully understood. Samples from different locations were collected from two broiler farms in Germany over a total of six production cycles. Samples were collected at days 1, 5, 10, 15, 21, 27, 34, 41 post-hatch and after cleaning and disinfection (C&D). A total of 1017 samples were collected f...
Source: Avian Pathology - March 25, 2024 Category: Pathology Authors: Jesper Tessin Arne Jung Amanda Silberborth Karl Rohn Jochen Schulz Christian Visscher Nicole Kemper Source Type: research

Detection of < em > Enterococcus cecorum < /em > to identify persistently contaminated locations using faecal and environmental samples in broiler houses of clinically healthy flocks
Avian Pathol. 2024 Mar 25:1-20. doi: 10.1080/03079457.2024.2334682. Online ahead of print.ABSTRACTWorldwide outbreaks make infections with pathogenic strains of Enterococcus cecorum (EC) one of the most important diseases in the broiler industry. Although research has increased knowledge about the pathogen, the transmission is not fully understood. Samples from different locations were collected from two broiler farms in Germany over a total of six production cycles. Samples were collected at days 1, 5, 10, 15, 21, 27, 34, 41 post-hatch and after cleaning and disinfection (C&D). A total of 1017 samples were collected f...
Source: Avian Pathology - March 25, 2024 Category: Pathology Authors: Jesper Tessin Arne Jung Amanda Silberborth Karl Rohn Jochen Schulz Christian Visscher Nicole Kemper Source Type: research

Integrated 16S rRNA sequencing and metagenomics insights into microbial dysbiosis and distinct virulence factors in inflammatory bowel disease
This study aims to elucidate the gut microbiota profiles in IBD patients and compare them with healthy controls in a western city of China.MethodsWe conducted a multicenter case-control study from the end of 2020, using 16S rRNA gene sequencing (n = 36) and metagenomic sequencing (n = 12) to analyze the gut microbiota of newly diagnosed IBD patients, including those with Crohn's disease (CD) and ulcerative colitis (UC).ResultsOur results demonstrated a significant enrichment of the phylum Proteobacteria, particularly the genus Escherichia-Shigella, in CD patients. Conversely, the genus Enterococcus was markedly increased i...
Source: Frontiers in Microbiology - March 25, 2024 Category: Microbiology Source Type: research