The association of olfactory dysfunction with depression in patients with early-onset Parkinson`s disease
This study aimed to evaluate the association between olfactory dysfunction and depression in patients with early-onset Parkinson's disease (EOPD). (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: T. Dang Thi Huyen, T. Nguyen Vinh, K. Nguyen Vinh, H. Le Thi, U. Ha Ngoc Le, K. Vo Ngoc Chung, T. Tran Ngoc Source Type: research

Targeting sedentary behavior decreases depressive symptoms and improves sleep in people with Parkinson ’s Disease
Background: Physical Therapy (PT) and regular exercise are an integral part of the management of Parkinson's Disease (PD). Exercise is also known to have a mitigating effect on depressive symptoms. There is increasing evidence that decreasing sedentary behavior is also a valuable tool to manage PD symptoms. We looked at the effect of decreasing sedentary behavior on depressive symptoms in PD by offering an opportunity to replace sedentary behavior with slow paced standing and stepping behavior in the home environment. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: M. van Emde Boas, C. Pongmala, A. Griggs, G. Carli, N.I. Bohnen Source Type: research

Synaptic density changes following electroconvulsive therapy: A longitudinal pilot study with PET-MR 11C-UCB-J imaging in late-life depression
Electroconvulsive therapy (ECT) is an effective treatment for late-life depression (LLD), but its exact mechanism is not fully understood. The neuroplasticity hypothesis suggests that ECT works by inducing seizures that lead to neurotrophic effects crucial for its success (1). Supporting the neuroplasticity hypothesis, preclinical research shows that electroconvulsive stimulation (ECS) enhances neurotrophic factors, promotes neurogenesis, boosts synaptogenesis, axonal sprouting, dendritic growth, and spine density, and alters synaptic circuitry in the hippocampus (2). (Source: BRAIN STIMULATION: Basic, Translational, and C...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 1, 2024 Category: Neurology Authors: Maarten Laroy, Thomas Vande Casteele, Margot Van Cauwenberge, Michel Koole, Patrick Dupont, Stefan Sunaert, Jan Van den Stock, Pascal Sienaert, Koen Van Laere, Mathieu Vandenbulcke, Louise Emsell, Filip Bouckaert Source Type: research

Case report —Depression with psychotic features as an atypical presentation of neurosyphilis
Timeline of treatment, symptoms, and medication over eight years since first admission. Key Clinical MessageRecurrent depression with psychotic features is an atypical presentation of neurosyphilis. This case emphasizes the polymorphic clinical presentation of neurosyphilis and how it mimics affective disorders with psychotic symptoms. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 30, 2024 Category: General Medicine Authors: Aykut Aytulun, Laura Sophie Grannemann, Colin R. MacKenzie, Alexandros Dimitrakopoulos, Francesca Pessanha ‐Schlegel, Daniel Kamp, Leonhard Schilbach Tags: CASE REPORT Source Type: research

Investigating mental health and well-being among MBA students during campus placement season in India
Mohammed Laeequddin, Kareem Abdul Waheed, Vinita Sahay Mental Health and Social Inclusion, Vol. ahead-of-print, No. ahead-of-print, pp.- This paper aims to identify the factors that influence students' mental health, particularly in the context of MBA students passing through an emotional phase of the placement season.A conceptual model through literature has been proposed. To test the proposed model of this study, a survey was conducted among the students of three MBA institutes of national reputation in India. The study's hypotheses were investigated using partial least squares-structural equations modeling and analysis...
Source: Mental Health and Social Inclusion - April 30, 2024 Category: Psychiatry Authors: Mohammed Laeequddin Kareem Abdul Waheed Vinita Sahay Source Type: research

Interpersonal sensitivity predicts slower change and less change in anxiety symptoms in cognitive behavioural therapy
CONCLUSIONS: Interpersonal sensitivity at baseline predicts less change and a slower rate of change in anxiety symptoms. Early detection of elevated interpersonal sensitivity can help therapists take action to address these barriers to successful treatment and help scientists build decision support tools that accurately predict the trajectory of change in anxiety symptoms for these patients.PMID:38685732 | DOI:10.1111/bjc.12470 (Source: The British Journal of Clinical Psychology)
Source: The British Journal of Clinical Psychology - April 30, 2024 Category: Psychiatry & Psychology Authors: Jiyoung Song Genevieve Freedman Letian Li Jacqueline B Persons Source Type: research

Examining processes of change for acceptance and commitment therapy and cognitive behavioral therapy self-help books with depressed college students
Cogn Behav Ther. 2024 Apr 30:1-16. doi: 10.1080/16506073.2024.2346854. Online ahead of print.ABSTRACTGiven the prevalence of depression, it is worthwhile to consider a variety of treatment approaches to reach as many sufferers as possible, including highly accessible formats such as self-help books. Books based in acceptance and commitment therapy (ACT) and cognitive behavioral therapy (CBT) propose to treat depression through distinct processes of change, though the degree to which these treatments are distinguishable in this format is unclear. Furthermore, it is possible that some individuals may respond better to therap...
Source: Cognitive Behaviour Therapy - April 30, 2024 Category: Psychiatry & Psychology Authors: Carter H Davis Michael P Twohig Michael E Levin Source Type: research

Perceived Control, Functional Status, Depressive Symptoms, and Anxiety: Mediating and Moderating Influences on Health-Related Quality of Life in Patients With Heart Failure
CONCLUSION: Functional status moderated the indirect effects of perceived control on HRQoL through DS and anxiety in patients with heart failure. Efforts to improve HRQoL by targeting perceived control may be more effective when considering DS and anxiety in patients with low to moderate levels of functional status.PMID:38687114 | DOI:10.1097/JCN.0000000000001100 (Source: The Journal of Cardiovascular Nursing)
Source: The Journal of Cardiovascular Nursing - April 30, 2024 Category: Nursing Authors: Ashmita Thapa JungHee Kang Misook L Chung Jia-Rong Wu Abigail Latimer Terry A Lennie Chin-Yen Lin Jessica Harman Thompson Geunyeong Cha Debra K Moser Source Type: research

Dorsal dentate gyrus mediated enriched environment-induced anxiolytic and antidepressant effects in cortical infarcted mice
This study aimed to explore the effectiveness of EE on emotional disorders after cerebral ischemia and its underling mechanism. In this study, sensorimotor cortical infarction was induced by photothrombosis with stable infarct location and volume, resulting in motor dysfunction, anxiety and depression-like behaviors in mice, with decreased ALFF and ReHo values and decreased c-fos expression in the infarction area and adjacent regions. Seven days' EE treatment significantly improved motor function of contralateral forelimb and exhibited anxiolytic and antidepressant effects in infarcted mice. Compared to the mice housing in...
Source: Experimental Neurology - April 30, 2024 Category: Neurology Authors: Dan Huang Yunhui Fan Jingjun Zhang Qianfeng Wang Ming Ding Ruiqing Hou Kewei Yu Xiao Xiao Yi Wu Junfa Wu Source Type: research

High Rates of Eye Surgery Cancellation in Veterans Related to Mental Health
CONCLUSIONS: There was a significant amount of eye surgery cancellations in veterans with variation by subspecialty and comorbid conditions. Having a psychiatric illness was correlated with increased rates of surgery cancellation amongst veterans. Areas to improve surgical utilization include risk stratification and increased support of vulnerable patients before surgery.PMID:38687601 | DOI:10.1093/milmed/usae230 (Source: Military Medicine)
Source: Military Medicine - April 30, 2024 Category: International Medicine & Public Health Authors: Justin Hanson Maggie Hui Jason C Strawbridge Sayan Chatterjee Kendall Goodyear JoAnn A Giaconi Irena Tsui Source Type: research

A Study on the Effects of Esketamine Combined with Comprehensive Nursing Intervention on Postoperative Pain, Postpartum Depression, and Quality of Life in Women Undergoing Cesarean Section
CONCLUSION: The application of esketamine combined with comprehensive nursing intervention after cesarean section has a positive impact on the pain relief, postpartum depression, and quality of life of parturients. This study provides new insights and guidance for clinical practice, potentially enhancing the postoperative experience of women undergoing cesarean section. These findings furnish healthcare professionals with valuable insights and guidance, fostering a nuanced and improved standard of care in obstetric practices.PMID:38687857 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 30, 2024 Category: Complementary Medicine Authors: Mei Jiang Jing Xu Source Type: research

The Role of Attentional Control in Mindfulness Intervention for Emotional Distress: A Randomized Controlled Trial With Longitudinal Mediation Analyses
CONCLUSIONS: The present trial provides evidence suggesting that mindfulness interventions may alleviate emotional distress through the enhancement of attentional control.TRIAL REGISTRATION: Chinese Clinical Trial Registry number: ChiCTR2200064140.PMID:38687203 | DOI:10.1002/cpp.2981 (Source: Clinical Psychology and Psychotherapy)
Source: Clinical Psychology and Psychotherapy - April 30, 2024 Category: Psychiatry Authors: Zhenzhen Wang Kaerqika Shalihaer Stefan G Hofmann Shixing Feng Xinghua Liu Source Type: research

Two-part models identifying predictors of cigarette, e-cigarette, and cannabis use and change in use over time among young adults in the US
CONCLUSIONS: Young adult substance use interventions should target high-risk subgroups and focus on distinct factors impacting use, including chronic, escalating, and decreasing use.SCIENTIFIC SIGNIFICANCE: This study advances the literature regarding distinct predictors of different substance use outcomes and provides unique data to inform interventions targeting young adult cigarette, e-cigarette, and cannabis use.PMID:38685757 | DOI:10.1111/ajad.13569 (Source: The American Journal on Addictions)
Source: The American Journal on Addictions - April 30, 2024 Category: Addiction Authors: Yan Wang Katelyn F Romm Mark C Edberg Jeffrey B Bingenheimer Cassidy R LoParco Yuxian Cui Carla J Berg Source Type: research

Two-part models identifying predictors of cigarette, e-cigarette, and cannabis use and change in use over time among young adults in the US
CONCLUSIONS: Young adult substance use interventions should target high-risk subgroups and focus on distinct factors impacting use, including chronic, escalating, and decreasing use.SCIENTIFIC SIGNIFICANCE: This study advances the literature regarding distinct predictors of different substance use outcomes and provides unique data to inform interventions targeting young adult cigarette, e-cigarette, and cannabis use.PMID:38685757 | DOI:10.1111/ajad.13569 (Source: American Journal on Addictions)
Source: American Journal on Addictions - April 30, 2024 Category: Addiction Authors: Yan Wang Katelyn F Romm Mark C Edberg Jeffrey B Bingenheimer Cassidy R LoParco Yuxian Cui Carla J Berg Source Type: research

Association of Lower Rostral Anterior Cingulate GABA+ and Dysregulated Cortisol Stress Response With Altered Functional Connectivity in Young Adults With Lifetime Depression: A Multimodal Imaging Investigation of Trait and State Effects
CONCLUSIONS: Lifetime MDD was characterized by reduced rACC GABA+ as well as dysregulated cortisol-related interactions between top-down control (frontoparietal) and threat (task-related) networks. These findings warrant further investigation of the role of GABA in the vulnerability to and treatment of MDD.PMID:38685857 | DOI:10.1176/appi.ajp.20230382 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - April 30, 2024 Category: Psychiatry Authors: Maria Ironside Jessica M Duda Amelia D Moser Laura M Holsen Chun S Zuo Fei Du Sarah Perlo Christine E Richards Xi Chen Lisa D Nickerson Kaylee E Null Shiba M Esfand Madeline M Alexander David J Crowley Meghan Lauze Madhusmita Misra Jill M Goldstein Diego Source Type: research