Roles of Nutrients in the Brain Development, Cognitive Function, and Mood of Dogs and Cats
Adv Exp Med Biol. 2024;1446:177-202. doi: 10.1007/978-3-031-54192-6_8.ABSTRACTThe brain is the central commander of all physical activities and the expression of emotions in animals. Its development and cognitive health critically depend on the neural network that consists of neurons, glial cells (namely, non-neuronal cells), and neurotransmitters (communicators between neurons). The latter include proteinogenic amino acids (e.g., L-glutamate, L-aspartate, and glycine) and their metabolites [e.g., γ-aminobutyrate, D-aspartate, D-serine, nitric oxide, carbon monoxide, hydrogen sulfide, and monoamines (e.g., dopamine, norep...
Source: Advances in Experimental Medicine and Biology - April 16, 2024 Category: Research Authors: Guoyao Wu Source Type: research

Walking Activity and Physical Function Among Mexican American Older Adults Over 9  Years of Follow Up
CONCLUSIONS: Mexican American older adults who engage in any walking activity are at reduced risk of low physical function, even those with disability. Interventions at the individual and community level are recommended to reduce physical function impairment, even in those with preexisting medical conditions or disability.PMID:38626896 | DOI:10.1123/jpah.2023-0266 (Source: Journal of Physical Activity and Health)
Source: Journal of Physical Activity and Health - April 16, 2024 Category: Sports Medicine Authors: Nicholas Tahmassi Soham Al Snih Source Type: research

A lentivirus-vectored feline erythropoietin gene therapy strategy in tissue culture and rodent models for the potential treatment of chronic renal disease-associated anemia
Am J Vet Res. 2024 Apr 20:1-12. doi: 10.2460/ajvr.23.12.0280. Online ahead of print.ABSTRACTOBJECTIVE: The aim of this study was to assess the efficacy and safety of a third-generation lentivirus-based vector encoding the feline erythropoietin (EPO) (feEPO) gene in vitro and in rodent models in vivo. This vector incorporates a genetic mechanism to facilitate the termination of the therapeutic effect in the event of supraphysiologic polycythemia, the herpes simplex virus thymidine kinase (HSV-TK) "suicide gene."ANIMALS: CFRK cells and replication-defective lentiviral vectors encoding feEPO were used for in vitro experiments...
Source: Cell Research - April 16, 2024 Category: Cytology Authors: Sarah E Cook Diego Castillo Tatiana Wolf Chadwick Hillman Katherine Bauer Sonyia Williams Brian G Murphy Source Type: research

Correlates of Impairment and Growth in Families of Young Autistic Children
J Autism Dev Disord. 2024 Apr 16. doi: 10.1007/s10803-024-06339-w. Online ahead of print.ABSTRACTThe purpose of this project was to investigate potential correlates of family life impairment in families of young autistic children. This project incorporated measures of specific child and parent challenges in addition to a commonly used unidimensional measure of autism characteristics. In this way, we could assess whether such challenges explain variance in family life impairment, and whether their inclusion diminish associations between autism characteristics and family life impairment. Cross-sectional data were collected f...
Source: Journal of Autism and Developmental Disorders - April 16, 2024 Category: Psychiatry Authors: Kristen T MacKenzie Mario J Crown Jessie B Northrup Elizabeth Rutenberg Amy G Hartman Carla A Mazefsky Source Type: research

Association between precarious employment and the onset of depressive symptoms in men and women: a 13-year longitudinal analysis in Korea (2009-2022)
CONCLUSIONS: Employment insecurity, inadequate income and lack of rights and protection may contribute to depressive symptoms. Therefore, PE serves as a significant social determinant of mental health among workers in Korea. Active policy efforts are warranted to improve the overall quality of employment in the workforce.PMID:38623756 | DOI:10.1017/S2045796024000258 (Source: Epidemiology and Psychiatric Sciences)
Source: Epidemiology and Psychiatric Sciences - April 16, 2024 Category: Psychiatry Authors: Seong-Uk Baek Jong-Uk Won Yu-Min Lee Jin-Ha Yoon Source Type: research

Bright light therapy versus physical exercise to prevent co-occurring depression in adolescents and young adults with attention-deficit/hyperactivity disorder: a multicentre, three-arm, randomised controlled, pilot phase-IIa trial
Eur Arch Psychiatry Clin Neurosci. 2024 Apr 16. doi: 10.1007/s00406-024-01784-1. Online ahead of print.ABSTRACTDepression is common in attention-deficit/hyperactivity disorder (ADHD), but preventive behavioural interventions are lacking. This randomised controlled, pilot phase-IIa trial aimed to study a physical exercise intervention (EI) and bright light therapy (BLT)-both implemented and monitored in an individual, naturalistic setting via a mobile health (m-health) system-for feasibility of trial design and interventions, and to estimate their effects on depressive symptoms in young people with ADHD. Two hundred seven p...
Source: European Archives of Psychiatry and Clinical Neuroscience - April 16, 2024 Category: Psychiatry Authors: Jutta S Mayer Laura Kohlhas Jacek Stermann Juliane Medda Geva A Brandt Oliver Grimm Adam D Pawley Philip Asherson Judit Palacio Sanchez Vanesa Richarte Douwe Bergsma Elena D Koch Adri à Muntaner-Mas Ulrich W Ebner-Priemer Meinhard Kieser Wolfgang Retz Fr Source Type: research

Walking Activity and Physical Function Among Mexican American Older Adults Over 9  Years of Follow Up
CONCLUSIONS: Mexican American older adults who engage in any walking activity are at reduced risk of low physical function, even those with disability. Interventions at the individual and community level are recommended to reduce physical function impairment, even in those with preexisting medical conditions or disability.PMID:38626896 | DOI:10.1123/jpah.2023-0266 (Source: Health Physics)
Source: Health Physics - April 16, 2024 Category: Physics Authors: Nicholas Tahmassi Soham Al Snih Source Type: research

The Association Between Stuttering Burden and Psychosocial Aspects of Life in Adults
CONCLUSIONS: Our results emphasize the need to be attentive to the diverse experiences and needs of PWS, rather than treating them as a homogeneous group. Our findings also stress the importance of personalized therapeutic strategies for individuals with stuttering, considering all aspects that could influence their stuttering burden. People with high-burden stuttering might, for example, have a higher need for psychological therapy to reduce stuttering-related anxiety. People with less emotional reactions but severe speech distortions may also have a moderate to high burden, but they may have a higher need for speech tech...
Source: Journal of speech, language, and hearing research : JSLHR - April 16, 2024 Category: Speech-Language Pathology Authors: Marscha M Engelen Marie-Christine J P Franken Lottie W Stipdonk Sarah E Horton Victoria E Jackson Sheena Reilly Angela T Morgan Simon E Fisher Sandra van Dulmen Else Eising Source Type: research

Poststroke Communication Ability Predicts Patient-Informant Discrepancies in Reported Activities and Participation
DISCUSSION: These findings highlight the importance of measuring participation by PROM. The PWA's experience of participation is not related to their level of language impairment and is predictably different from their care partners' perspective. As others have also reported, "mild" aphasia is not so mild to the PWA. Similarly, "severe" may not be so severe to the PWA. Further research is needed to connect these findings with counseling and caregiver education. Research on response processes (e.g., response shift) is also warranted.PMID:38625105 | DOI:10.1044/2024_AJSLP-23-00322 (Source: American Journal of Speech-Language Pathology)
Source: American Journal of Speech-Language Pathology - April 16, 2024 Category: Speech-Language Pathology Authors: Courtney C Jewell Stacy M Harnish Jennifer Brello Alyssa M Lanzi Matthew L Cohen Source Type: research

Psychosocial Distress Among Certified Nursing Assistants in Long-Term Care During the COVID-19 Pandemic: A Social Ecological Model Informed Scoping Review
CONCLUSIONS & CLINICAL IMPLICATIONS: This review identifies specific targets for intervention for psychosocial distress among CNAs in LTC at multiple levels, including job clarity; workload; facility culture; community relations; and policy. These intervention targets remain relevant to the LTC industry beyond the context of the COVID-19 pandemic.PMID:38622883 | DOI:10.1080/07317115.2024.2337137 (Source: Clinical Gerontologist)
Source: Clinical Gerontologist - April 16, 2024 Category: Geriatrics Authors: Evan Plys Nina Ahmad Andrea Wei Roy A Thompson E-Shien Chang Jenna Locke Jessica G Bell Ana-Maria Vranceanu Ruth Palan Lopez Source Type: research

A PRISMA Scoping Review to Explore Interventions to Prevent Firearm-Related Injury and Suicide in Older Adults
CONCLUSIONS: Further research into adapting interventions to meet the clinical needs of older adults and treatment efficacy trials is necessary.CLINICAL IMPLICATIONS: Training healthcare providers to conduct firearm safety interventions with older adults may be an acceptable and impactful avenue to prevent suicide.PMID:38626064 | DOI:10.1080/07317115.2024.2339366 (Source: Clinical Gerontologist)
Source: Clinical Gerontologist - April 16, 2024 Category: Geriatrics Authors: Lakshmi Chennapragada Terra Osterberg Madison Strouse Sarah R Sullivan Chana Silver Mary LaMarca Caroline Boucher Emilia Fonseca Marianne Goodman Source Type: research

Effectiveness of interventions to help mitigate the influence of social networks on anorexia and bulimia nervosa: a systematic review
CONCLUSIONS: Longer-lasting interventions can improve body satisfaction (one year) and depressive symptoms (six months), especially in women. Interventions should include attention to self-criticism, self-perception, self-esteem, body image, nutritional management, and media literacy skills.PMID:38626133 | DOI:10.23938/ASSN.1074 (Source: Anales del Sistema Sanitario de Navarra)
Source: Anales del Sistema Sanitario de Navarra - April 16, 2024 Category: General Medicine Authors: Noelia Lozano-Mu ñoz Álvaro Borrallo-Riego Mar ía Dolores Guerra-Martín Source Type: research

Network Analysis of Dyadic Burdens, Psychological Disorders, Psychological Resilience, and Illness- or Caregiving-Related Beliefs in Patients With Chronic Heart Failure and Their Caregivers
CONCLUSIONS: The findings illustrated extensive interconnections among dyadic health components in CHF dyads. These findings underscored the significance of managing and intervening with patients and caregivers as a dyadic whole. Given the strong and frequent associations of patients' anxiety, depression, and psychological resilience with other nodes in the network, interventions targeting these nodes may enhance the overall network health of CHF dyads.PMID:38622773 | DOI:10.1097/JCN.0000000000001098 (Source: The Journal of Cardiovascular Nursing)
Source: The Journal of Cardiovascular Nursing - April 16, 2024 Category: Nursing Authors: Yaqi Wang Xueying Xu Qingyun Lv Yue Zhao Xiaonan Zhang Xiaoying Zang Source Type: research

Impact of COVID-19 restrictions on self-poisoning behaviour with mild analgesics in Danish youth
CONCLUSION: These findings indicate that the restrictions enforced during the second lockdown greatly impacted youth mental health, especially girls, leading to an 85% increase in self-poisonings. We hope for increased awareness of mental health in children and adolescents during possible future lockdowns.PMID:38625374 | DOI:10.1080/08039488.2024.2339433 (Source: Nordic Journal of Psychiatry)
Source: Nordic Journal of Psychiatry - April 16, 2024 Category: Psychiatry Authors: Gurbhej Singh Jonathan Pommer Hansen Ditte Hulgaard Mads Damkj ær Erik Christiansen Source Type: research

Adjustment and homesickness in hospitalised children: A systematic review
The objectives of this review were to synthesise the qualitative and quantitative literature on psychosocial factors associated with hospital adjustment and to identify risk and protective factors that influence the adjustment process. The literature search (1980 to February 2024: CINAHL / Embase / Medline / PsychINFO and Web of Science databases) identified thirty-four studies. Poor hospital adjustment, anxiety, depression and homesickness, were reported by the majority of hospitalised children. Several demographic and psychosocial factors were identified in the quantitative synthesis to contribute to poor adjustment. Chi...
Source: Clinical Psychology Review - April 16, 2024 Category: Psychiatry & Psychology Authors: Eleni Andrea Demetriou Kelsie Anne Boulton Michael Russell Bowden Adam John Guastella Source Type: research