Pain Severity and Alcohol Use Among Daily Tobacco Cigarette Smokers.
Abstract BACKGROUND AND OBJECTIVES: Pain is associated with hazardous alcohol use. Drinkers have reported using alcohol for pain-coping, and negative affect may be a key mechanism in pain-induced motivation to drink. However, no previous study has examined pain severity in relation to alcohol consumption, dependence, and alcohol-related consequences. Moreover, no studies have examined pain-alcohol interrelations among tobacco cigarette smokers. These secondary analyses tested the hypotheses that greater past 4-week pain severity would be positively associated with indices of hazardous drinking (ie, quantity/freque...
Source: American Journal on Addictions - February 3, 2020 Category: Addiction Authors: LaRowe LR, Powers JM, Paladino MB, Ditre JW Tags: Am J Addict Source Type: research

GRIN2B Gene Polymorphism in Chronic Ketamine Users.
CONCLUSION AND SCIENTIFIC SIGNIFICANCE: GRIN2B gene polymorphism may play a role in ketamine abuse. (Am J Addict 2020;00:00-00). PMID: 31957106 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - January 19, 2020 Category: Addiction Authors: Fan N, An L, Zhang M, He H, Zhou Y, Ou Y Tags: Am J Addict Source Type: research

Does Cannabis Dependence Add on to the Neurocognitive Impairment Among Patients With Opioid Dependence? A Cross-Sectional Comparative Study.
CONCLUSIONS: Opioid dependence is associated with impairments in decision making, executive function, working memory, and attention. Co-morbid cannabis dependence had similar profiles of cognitive impairments. SCIENTIFIC SIGNIFICANCE: Co-morbid cannabis dependence might not add on to the existing cognitive dysfunction in opioid dependence. Further studies should be done with a larger sample. (Am J Addict 2020;00:00-00). PMID: 31951069 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - January 17, 2020 Category: Addiction Authors: Ghosh A, Basu D, Mattoo SK, Kumar Rana D, Roub F Tags: Am J Addict Source Type: research

Predictors of Medication Utilization for Opioid Use Disorder Among Medicaid-Insured HIV Patients in New York.
CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: A substantial number of patients with HIV and OUD did not receive MAT. Findings suggest that there are opportunities to improve OUD care for patients with HIV and OUD, particularly among the younger generation, blacks, individuals living outside of New York City, and among those with serious psychiatric conditions. This initial study suggests that an additional research is needed to better understand how the gap in care affects this population. (Am J Addict 2020;00:00-00). PMID: 31951083 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - January 17, 2020 Category: Addiction Authors: Choi S, Yerneni R, Healy S, Goyal M, Neighbors CJ Tags: Am J Addict Source Type: research

Sex Differences in Korsakoff's Syndrome for Inhibition but Not for Episodic Memory or Flexibility.
CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Our findings highlight cognitive sex differences in KS in executive function. Critically, our findings are the first quantitative data about episodic performances (and cognitive performances in general) of women and men with KS. (Am J Addict 2020;00:00-00). PMID: 31943522 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - January 15, 2020 Category: Addiction Authors: El Haj M, Kessels RPC, Nandrino JL Tags: Am J Addict Source Type: research

Impact of Medications for Opioid Use Disorder on Discharge Against Medical Advice Among People Who Inject Drugs Hospitalized for Infective Endocarditis.
CONCLUSION AND SCIENTIFIC SIGNIFICANCE: PWID hospitalized for endocarditis are at high risk for discharge AMA but more research is needed to understand the impact of MOUD. (Am J Addict 2020;00:00-00). PMID: 31930608 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - January 12, 2020 Category: Addiction Authors: Suzuki J, Robinson D, Mosquera M, Solomon DA, Montgomery MW, Price CD, Johnson JA, Martin B, Liebschutz JW, Schnipper JL, Weiss RD Tags: Am J Addict Source Type: research

Methamphetamine Use and Sexual Risk Behaviors among Men Who Have Sex With Men in a Mexico-US Border City.
This study aims to contribute to the limited literature of meth use and sexual risk behaviors among Latino MSM on the Mexico-US border. METHODS: Data were drawn from the Meth Pilot Study (2014-2015) among men who use meth (n = 100). Descriptive statistics and bivariate analysis comparing MSM to non-MSM were conducted using Pearson's χ2 test, Fisher's exact tests, and Mann-Whitney U test; all tests were conducted using SPSS v.25. RESULTS: Most participants obtained meth in El Paso, Texas (87.2%), used meth orally (65.2%) or smoked (78.3%), and the most common reason for initiation was curiosity. ...
Source: American Journal on Addictions - January 7, 2020 Category: Addiction Authors: Loza O, Curiel ZV, Beltran O, Ramos R Tags: Am J Addict Source Type: research

Cumulative Risk of Substance Use in Community College Students.
CONCLUSIONS: Different strategies for prevention and intervention may be necessary to effectively address different forms of substance use in this population. SCIENTIFIC SIGNIFICANCE: The risk domain profiles related to specific drugs may lead to targeted interventions to reduce substance use in community college students. (Am J Addict 2020;00:00-00). PMID: 31898858 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - January 3, 2020 Category: Addiction Authors: Salgado García F, Bursac Z, Derefinko KJ Tags: Am J Addict Source Type: research

Physician and Pharmacist: Attitudes, Facilitators, and Barriers to Prescribing Naloxone for Home Rescue.
CONCLUSION: In this study, we examined barriers and facilitators to naloxone prescribing. Although previous studies have shown that health care providers endorsed similar barriers, our study indicates that some of those barriers persist despite a concerted effort to educate and promote prescribing via an OEND. While our study is limited by a small, selective sample size the results indicate that improvements to our OEND program are warranted. SCIENTIFIC SIGNIFICANCE: Our study addressed an unexplored area of OEND research and may inform future program development. (Am J Addict 2019;00:00-00). PMID: 31804746 [PubM...
Source: American Journal on Addictions - December 5, 2019 Category: Addiction Authors: Martino JG, Smith SR, Rafie S, Rafie S, Marienfeld C Tags: Am J Addict Source Type: research

Brief Report: Problem Gambling in International and Domestic University Students.
CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Future research is required to elucidate problem gambling risk and protective factors in this ethnic minority subgroup, with a view to guide culturally sensitive initiatives. (Am J Addict 2019;00:00-00). PMID: 31799775 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - December 3, 2019 Category: Addiction Authors: Dowling NA, Brown M, Aarsman S, Merkouris SS Tags: Am J Addict Source Type: research

Naloxone-Induced Withdrawal in Individuals With and Without Fentanyl-Positive Urine Samples.
Abstract BACKGROUND AND OBJECTIVE: This retrospective analysis of data from heroin users screening for clinical research, sought to determine if more naloxone is needed to precipitate opioid withdrawal among those who regularly use heroin with fentanyl, as opposed to those who use heroin without fentanyl. METHODS: Over the course of three to five screening visits, participants completed assessments of drug use, along with urine toxicology tests at each visit. To test for opioid dependence, 29 participants completed a modified Wang test (score: 0-150) during which an intramuscular dose of naloxone (0.2-0.4&thi...
Source: American Journal on Addictions - November 29, 2019 Category: Addiction Authors: Jones JD, Sherwin E, Martinez S, Comer SD Tags: Am J Addict Source Type: research

Distress-Related Internalizing Symptoms Interact With Externalizing Symptoms to Predict Alcohol Problems in an Inpatient Adolescent Sample.
CONCLUSIONS: In this clinical sample, distress-related internalizing symptomatology was associated with risk for, and not protection against, hazardous AU, but only when accompanied by high externalizing symptoms. SCIENTIFIC SIGNIFICANCE: Findings suggest that whether or not internalizing symptoms operate synergistically with externalizing symptoms to predict hazardous AU depends on the subdomain of internalizing symptoms (distress vs fear) and perhaps the type of sample (ie, clinical vs community). (Am J Addict 2019:00:00-00). PMID: 31782592 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - November 29, 2019 Category: Addiction Authors: Egerton GA, Jenzer T, Blayney JA, Kimber J, Colder CR, Read JP Tags: Am J Addict Source Type: research

Association of Craving and Depressive Symptoms in Ketamine-Dependent Patients Undergoing Withdrawal Treatment.
CONCLUSIONS: We observed a high prevalence of depression in patients with KD, particularly those with higher cravings. Patients with greater cravings and severer depression might require a longer duration of withdrawal treatment. SCIENTIFIC SIGNIFICANCE: This research provides intimal evidence for an association between depression and craving in patients with KD. Screening and management of depression are recommended for this population. (Am J Addict 2019;00:00-00). PMID: 31691402 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - November 6, 2019 Category: Addiction Authors: Chen LY, Chen CK, Chen CH, Chang HM, Huang MC, Xu K Tags: Am J Addict Source Type: research

Case Series: Limited Opioid Withdrawal With Use of Transdermal Buprenorphine to Bridge to Sublingual Buprenorphine in Hospitalized Patients.
CONCLUSIONS: Bridging to sublingual therapy with transdermal buprenorphine patches was feasible without withdrawal symptoms. SCIENTIFIC SIGNIFICANCE: This strategy may facilitate buprenorphine therapy in hospital inpatients. (Am J Addict 2019;00:1-4). PMID: 31626394 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - October 18, 2019 Category: Addiction Authors: Tang VM, Lam-Shang-Leen J, Brothers TD, Hansen K, Caudarella A, Lamba W, Guimond T Tags: Am J Addict Source Type: research

Comparing Changes in Controlled Substance Prescribing Trends by Provider Type.
CONCLUSIONS: Although monitoring and continuing education requirements are similar across all providers in Kentucky, differences in prescription trends for Schedule II opioids and stimulants were noted for physicians, APRNs, and dentists. SCIENTIFIC SIGNIFICANCE: Changes in prescribing following introduction of mandatory use of KASPER markedly differed based on provider type, with increases observed for APRNs compared with physicians and dentists. These findings advance prior research by providing a detailed examination of prescribing trends by provider type subsequent to a PDMPs mandatory use law. (Am J Addict 2019;0...
Source: American Journal on Addictions - October 10, 2019 Category: Addiction Authors: Meadows AL, Strickland JC, Qalbani S, Conner KL, Su A, Rush CR Tags: Am J Addict Source Type: research

Cannabis and Cannabinoids in Mood and Anxiety Disorders: Impact on Illness Onset and Course, and Assessment of Therapeutic Potential.
CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: These conclusions are limited by a lack of well-controlled longitudinal studies. We suggest that future research be directed toward high-quality, prospective studies of cannabis in clinical populations with mood and ADs, in addition to controlled studies of cannabinoid constituents and pharmaceuticals in these populations. (Am J Addict 2019;00:00-00). PMID: 31577377 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - October 2, 2019 Category: Addiction Authors: Botsford SL, Yang S, George TP Tags: Am J Addict Source Type: research

Differential posttreatment outcomes of methylphenidate for smoking cessation for individuals With ADHD.
CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: OROS-MPH promotes abstinence beyond the course of treatment for patients with more severe ADHD, while the paradoxical effects in the lower baseline severity group is not persistent after medication discontinuation. Targeting ADHD in smoking cessation as a comorbidity therefore can have broader impact with more precise patient selection. (Am J Addict). PMID: 31538372 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - September 19, 2019 Category: Addiction Authors: Luo SX, Covey LS, Hu MC, Winhusen TM, Nunes EV Tags: Am J Addict Source Type: research

Cannabis, Decision-Making, and Online Assistance Seeking.
CONCLUSIONS: Decisional style influenced cannabis use and symptoms. Those people with cannabis-related problems that did not seek online assistance were defensively avoidant. SCIENTIFIC SIGNIFICANCE: Procrastination is a feature of problematic cannabis use. Online offers of assistance may be ignored by defensively avoidant CUD clients. (Am J Addict 2019;00:1-7). PMID: 31532567 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - September 18, 2019 Category: Addiction Authors: Evans M, Ogeil RP, Phillips JG Tags: Am J Addict Source Type: research

Review: Non-invasive brain stimulation in behavioral addictions: insights from direct comparisons with substance use disorders.
CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Direct comparisons between BAs and SUDs revealed discrepancies between behavioral and neurophysiological outcomes, but overall, common and distinctive characteristics underlying each disorder. The lack of complete overlap between BAs and SUDs suggests that investigating the cognitive and neurophysiological features of BAs to create individual NIBS protocols that target risk-factors associated specifically with BAs, might be more effective than transferring protocols from SUDs to BAs. Individualizing NIBS protocols to target specific risk-factors associated with each BA might help to...
Source: American Journal on Addictions - September 12, 2019 Category: Addiction Authors: Gomis-Vicent E, Thoma V, Turner JJD, Hill KP, Pascual-Leone A Tags: Am J Addict Source Type: research

"Side Effects" Observed within ~1-90 Days after Cannabis Onset: Epidemiological Estimates for the United States, 2004-2014.
CONCLUSION AND SCIENTIFIC SIGNIFICANCE: In these US community samples of cannabis initiates studied soon after first use, the vast majority were free of individual SE experiences counted toward Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition cannabis use disorder diagnoses. For a minority, SE-SE pairs might indicate syndrome formation. These epidemiological meta-analysis estimates might find use in refinement of clinical practice guidelines for fast effective syndrome screens when primary care patients are seen soon after cannabis onset, akin to clinical screening guides designed for newly incident dr...
Source: American Journal on Addictions - September 5, 2019 Category: Addiction Authors: Alcover KC, Thompson C, Anthony JC Tags: Am J Addict Source Type: research

Use of Guanfacine for Cannabis use Disorder and Related Symptomology.
CONCLUSIONS: Compared with former studies, we could not prove significant improvement in sleep or decrease of negative symptoms, but we found trends for increased positive mood symptoms. Our data did not show significant effects of guanfacine on withdrawal symptoms or craving. Due to early and longer cannabis use, our subjects indicate a great severity of illness increasing the likelihood of treatment resistance. SCIENTIFIC SIGNIFICANCE: On the basis of trends demonstrated here and other lines of evidence, further investigation is warranted regarding the utility of guanfacine as a potential treatment for CUD. (Am J Ad...
Source: American Journal on Addictions - September 4, 2019 Category: Addiction Authors: Holst M, Mathai DS, Patel MM, Rodgman C, Keller J, Hussain MZ, De La Garza R, Kosten TR, Verrico CD Tags: Am J Addict Source Type: research

Lofexidine in Combination with Oral Naltrexone for Opioid Use Disorder Relapse Prevention: A pilot Randomized, Double-Blind, Placebo-Controlled Study.
Abstract BACKGROUND AND OBJECTIVES: Lofexidine (LFX), an α2A adrenergic receptor agonist, known to alleviate opioid withdrawal symptoms, was assessed in combination with oral naltrexone (NTX) for effects on opioid use outcomes and NTX treatment compliance. METHODS: Detoxified individuals (ages 18-55, 80% male) with opioid use disorder Diagnostic and Statistical Manual of Mental Disorders, 4th edition were randomized to 2.4 mg/day of LFX (n = 26) or Placebo (PBO, n = 31) in a double-blind manner for 12 weeks of treatment. NTX compliance, opioid-free urine samples, opioi...
Source: American Journal on Addictions - August 26, 2019 Category: Addiction Authors: Hermes G, Hyman SM, Fogelman N, Kosten TR, Sinha R Tags: Am J Addict Source Type: research

Craving Mediates the Relation between Impulsivity and Alcohol Consumption Among University Students.
Abstract BACKGROUND AND OBJECTIVES: The relationship between impulsivity and craving in severe alcohol use disorders is well established, but the presence and characteristics of this link in University students are still to be established. The present study aims to better understand the relationship between impulsivity and craving in university students and to determine the influence of these variables on alcohol consumption characteristics. METHODS: A large sample of university students (N = 1055, mean age: 20.9 years; 713 women) completed an online questionnaire to evaluate alcohol use, impuls...
Source: American Journal on Addictions - August 19, 2019 Category: Addiction Authors: Flaudias V, Maurage P, Izaute M, de Chazeron I, Brousse G, Chakroun-Baggioni N Tags: Am J Addict Source Type: research

Psychopathology and Hypersexuality among Veterans with and without Histories of Alcohol-use Disorders.
CONCLUSIONS: We found differences among veterans with lifetime AUDs compared with those without on select measures of psychopathology, sexual behavior, and hypersexuality. SCIENTIFIC SIGNIFICANCE: Further screening for substance-use disorders and hypersexuality in Veterans Affairs is strongly encouraged while veterans are transitioning back into civilian life (Am J Addict 2019;00:00-00). PMID: 31393652 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - August 8, 2019 Category: Addiction Authors: Moisson J, Potenza MN, Shirk SD, Hoff RA, Park CL, Kraus SW Tags: Am J Addict Source Type: research

Differential Effects of Anxiety Sensitivity on E-Cigarettes Processes: The Importance of E-Cigarette Quit Attempt History.
CONCLUSIONS: Findings identify e-cigarette users who fail to quit as a potential vulnerable subgroup of users who experience more strongly held perceptions about e-cigarettes because of increased AS. SCIENTIFIC SIGNIFICANCE: This work provides initial evidence for a conceptual model in which levels of AS and e-cigarette processes are strengthened by and differ across e-cigarette quit attempt history. PMID: 31381212 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - August 5, 2019 Category: Addiction Authors: Garey L, Smit T, Mayorga NA, Peraza N, Nizio P, Otto MW, Zvolensky MJ Tags: Am J Addict Source Type: research

Acute Carbon Monoxide Poisoning Secondary to Cigarette Smoking in a 40-Year-Old Man: A Case Report.
CONCLUSIONS: Therefore, it is important to recognize cigarette smoke as a significant source of carbon monoxide exposure. SCIENTIFIC SIGNIFICANCE: While the negative effects of cigarette smoking are often perceived as being chronic and only coming to fruition after numerous years of exposure, it is important for both physicians and patients to recognize the possibility for potentially life-threatening acute toxicity secondary to carbon monoxide exposure. (Am J Addict 2019;00:1-3). PMID: 31348564 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - July 26, 2019 Category: Addiction Authors: Neilsen BK, Aloi J, Sharma A Tags: Am J Addict Source Type: research

Effects of Tobacco Smoking Status on Verbal Learning and Memory in Patients With Schizophrenia and Non-Psychiatric Controls.
CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Acute cigarette smoking and abstinence may selectively alter verbal learning and memory deficits in smokers with schizophrenia compared to nonpsychiatric smoking controls and nonsmokers, but additional studies are needed to confirm the preliminary findings in this small sample. (Am J Addict 2019;00:1-9). PMID: 31291035 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - July 10, 2019 Category: Addiction Authors: Kozak K, Lowe DJE, George TP Tags: Am J Addict Source Type: research

Risk Factors for Overdose in Young People Who Received Substance Use Disorder Treatment.
Abstract BACKGROUND AND OBJECTIVES: To identify substance and psychiatric predictors of overdose (OD) in young people with substance use disorders (SUDs) who received treatment. METHODS: We conducted a retrospective review of consecutive medical records of young people who were evaluated in a SUD program between 2012 and 2013 and received treatment. An independent group of patients from the same program who received treatment and had a fatal OD were also included in the sample. OD was defined as substance use associated with a significant impairment in level of consciousness without intention of self-harm, or...
Source: American Journal on Addictions - July 10, 2019 Category: Addiction Authors: Yule AM, Carrellas NW, DiSalvo M, Lyons RM, McKowen JW, Nargiso JE, Bergman BG, Kelly JF, Wilens TE Tags: Am J Addict Source Type: research

Erratum: Gender Differences in Mental Health and Substance Use Disorders and Related Healthcare Services Utilization.
PMID: 31233262 [PubMed - in process] (Source: American Journal on Addictions)
Source: American Journal on Addictions - June 25, 2019 Category: Addiction Authors: Brand E, Rodriguez-Monguio R, Volber R Tags: Am J Addict Source Type: research

Commentary: A Novel Therapeutic for Opioid Use Disorder Targeting the Cholinergic System.
PMID: 31165540 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - June 4, 2019 Category: Addiction Authors: Moeller SJ, Abi-Dargham A Tags: Am J Addict Source Type: research

Double-Blind Placebo-Controlled Trial of Galantamine for Methadone-Maintained Individuals With Cocaine Use Disorder: Secondary Analysis of Effects on Illicit Opioid Use.
CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: If these results are supported in future trials, galantamine may hold promise across multiple drugs of abuse, including opioids. (Am J Addict 2019:1-8). PMID: 31165574 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - June 4, 2019 Category: Addiction Authors: Carroll KM, DeVito EE, Yip SW, Nich C, Sofuoglu M Tags: Am J Addict Source Type: research

Review: Sex-Based Differences in Treatment Outcomes for Persons With Opioid Use Disorder.
CONCLUSIONS: While much of the literature on this topic is subject to potential cohort effects, interventions that address co-occurring mental health conditions and psychosocial stress might improve treatment outcomes for women with OUD. SCIENTIFIC SIGNIFICANCE: Funding agencies and researchers should focus attention toward human laboratory studies and clinical trials that are prospectively designed to assess sex-based differences in OUD recovery. (Am J Addict 2019:1-14). PMID: 31131505 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - May 26, 2019 Category: Addiction Authors: Huhn AS, Berry MS, Dunn KE Tags: Am J Addict Source Type: research

Cannabis Use Disorder and Epilepsy: A Cross-National Analysis of 657  072 Hospitalized Patients.
CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: With the increasing prevalence of medical marijuana legalization, there is increased use of medicinal marijuana. Studies of cannabidiol and marijuana for epilepsy have been highly publicized, leading to its off-label use for treatment. There is limited evidence to suggest that the cannabinoids may also induce a seizure. This study found that CUD is independently associated with a 56% increased likelihood of epilepsy hospitalization and this association persists even after adjusting for other substance use disorders and confounders. (Am J Addict 2019;1-9). PMID: 31124592 [PubMed...
Source: American Journal on Addictions - May 24, 2019 Category: Addiction Authors: Patel RS, Mekala HM, Tankersley WE Tags: Am J Addict Source Type: research

Brief Report: Sex Differences in Substance Use, Mental Health, and Impaired Driving Among Rural DUI Offenders.
CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: This initial examination of sex differences among rural DUI offenders suggests additional research is needed to better understand their substance use and mental health problems and whether different treatment approaches are needed. (Am J Addict 2017:1-4). PMID: 31115119 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - May 21, 2019 Category: Addiction Authors: Webster JM, Staton M, Dickson MF Tags: Am J Addict Source Type: research

Codependency and Prefrontal Cortex Functioning: Preliminary Examination of Substance Use Disorder Impacted Family Members.
CONCLUSIONS: The left dorsomedial PFC is associated with executive functioning during responses to emotional and social situations. Findings may suggest that family members experiencing codependency may be limited in effectively responding to their SUD loved-one, and highlight the importance of systemic treatment and family member recovery. SCIENTIFIC SIGNIFICANCE: Codependency is often discussed as a learned condition and research has only recently examined brain processes of family members with a loved-one with a SUD. This research is the first to demonstrate an association between codependency and PFC functioning. ...
Source: American Journal on Addictions - May 15, 2019 Category: Addiction Authors: Zielinski M, Bradshaw S, Mullet N, Hawkins L, Shumway S, Story Chavez M Tags: Am J Addict Source Type: research

Pharmacogenetic role of dopamine transporter (SLC6A3) variation on response to disulfiram treatment for cocaine addiction.
CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: We found that patients with genetically higher DAT levels had better treatment outcomes with disulfiram pharmacotherapy of cocaine dependence than those with lower DAT levels. (Am J Addict 2019:1-7). PMID: 31087723 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - May 14, 2019 Category: Addiction Authors: Kampangkaew JP, Spellicy CJ, Nielsen EM, Harding MJ, Ye A, Hamon SC, Kosten TR, Nielsen DA Tags: Am J Addict Source Type: research

Adverse Childhood Experiences and E-Cigarette Use During Young Adulthood.
CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Our results suggest that young adults with a history of CM might be vulnerable to e-cigarette use and that NU played a significant role in linking CM to lifetime e-cigarette use. Addressing NU in young adults with a history of CM might be a useful avenue for preventing e-cigarette use in this population. PMID: 31069879 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - May 8, 2019 Category: Addiction Authors: Shin SH, Conley D, Ksinan Jiskrova G, Wills TA Tags: Am J Addict Source Type: research

Long-Term Retention in an Outpatient Behavioral Health Clinic With Buprenorphine.
CONCLUSION: During the study period, 52.7% and 35.5% of BHC patients treated with buprenorphine were retained for 1 and 2 years, respectively, comparable to the studies performed within primary care. Providing buprenorphine treatment within mental health clinics may serve patients who are already engaged with mental health providers but are reluctant to start new treatment within another treatment setting. SCIENTIFIC SIGNIFICANCE: Identifying common predictors of retention can help determine which patients require additional substance use treatment support. (Am J Addict 2019:1-8). PMID: 31066985 [PubMed - as supp...
Source: American Journal on Addictions - May 8, 2019 Category: Addiction Authors: Montalvo C, Stankiewicz B, Brochier A, Henderson DC, Borba CPC Tags: Am J Addict Source Type: research

A Pilot Study of E-Cigarette Na ïve Cigarette Smokers and the Effects on Craving After Acute Exposure to E-Cigarettes in the Laboratory.
CONCLUSION AND SCIENTIFIC SIGNIFICANCE: This experiment provides data demonstrating that e-cigarettes did not reduce craving or smoking severity in e-cigarette naïve users. However, since this was a pilot study, the conclusions that can be drawn are limited. (Am J Addict 2017:1-6). PMID: 31066987 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - May 8, 2019 Category: Addiction Authors: De La Garza R, Shuman SL, Yammine L, Yoon JH, Salas R, Holst M Tags: Am J Addict Source Type: research

A Retrospective 4-year Outcome Study of Veterans Admitted to an Acute Inpatient Detoxification Unit for Opioid Use Disorder.
CONCLUSION AND SCIENTIFIC SIGNIFICANCE: OUD carries a shockingly high lethality in Veterans requiring inpatient admission for opioid withdrawal, particularly when there are untreated comorbid psychiatric conditions. RR and MAT are correlated to lower all-cause mortality in this population and should be highly utilized. Given the extremely high mortality, intensive system-wide interventions are needed for the care of Veterans with OUD. On the basis of the reduced predicted mortality with RR and MAT, further research into novel MATs as well as refining RR programs should be a major focus. (Am J Addict 2019:1-6). PMID: 3...
Source: American Journal on Addictions - May 8, 2019 Category: Addiction Authors: Li KJ, Smedberg DL, DeLisi LE Tags: Am J Addict Source Type: research

Use of "Lean" Among Electronic Dance Music Party Attendees.
CONCLUSIONS: While use of Lean is not as prevalent as use of various other drugs (eg, ecstasy) in this high-risk population, over a tenth have tried it and/or are willing to use it if offered. SCIENTIFIC SIGNIFICANCE: Prevention efforts need to target potential users as frequent use of beverages containing codeine products can lead to dependence. (Am J Addict 2019:1-6). PMID: 31041819 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - April 30, 2019 Category: Addiction Authors: Palamar JJ Tags: Am J Addict Source Type: research

Predictors of Substance Use Latent Classes Among American Indian Youth Attending Schools On or Near Reservations.
CONCLUSIONS: Early initiation of alcohol or marijuana is strongly related to being in a substance-using class for AI youth. Because these youth tend to initiate use earlier that other US youth, prevention resources should be targeted to reaching them and their families before age 12. SCIENTIFIC SIGNIFICANCE: Predictors of latent classes of substance use were identified for reservation-based AI youth. While the classes were identical for 7 to 8 grade and 9 to 12 grade youth, predictors varied across grade group, which may inform how best to develop prevention efforts unique to middle and high school AI youth. PMID...
Source: American Journal on Addictions - April 30, 2019 Category: Addiction Authors: Swaim RC, Stanley LR Tags: Am J Addict Source Type: research

Demographic, Cannabis Use, and Depressive Correlates of Cannabis Use Consequences in Regular Cannabis Users.
CONCLUSIONS: Regular cannabis users report consequences of use, which can be grouped into content-specific subgroups. Individual characteristics are differentially associated with these subgroups. SCIENTIFIC SIGNIFICANCE: Understanding which individual characteristics are related to cannabis use sequelae could help identify those at risk for greater consequences, thus leading to improved assessment and treatment interventions. PMID: 31016818 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - April 23, 2019 Category: Addiction Authors: Struble CA, Ellis JD, Cairncross M, Lister JJ, Lundahl LH Tags: Am J Addict Source Type: research

Initiation Sequence of E-Cigarette and Cigarette Smoking among US Adolescents: A National Study.
CONCLUSIONS: Adolescents who report a history of both e-cigarette use and cigarette smoking should be considered at high risk for substance-related problems. Early initiation of e-cigarette use is a signal for other substance use. SCIENTIFIC SIGNIFICANCE: Youth substance use prevention programs and prospective studies must take into account polysubstance use when addressing the relationships between e-cigarette use and cigarette smoking. (Am J Addict 2019;00:1-10). PMID: 30993786 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - April 16, 2019 Category: Addiction Authors: McCabe SE, Veliz P, McCabe VV, Boyd CJ Tags: Am J Addict Source Type: research

Evaluation of an Online Residency Training in Tobacco Use Disorder.
CONCLUSIONS: Many residents reported feeling not well prepared to treat TUD from prior education. The vast majority (98%) felt the program enhanced their professional experience somewhat or substantially or would recommend the program to others (82%). SCIENTIFIC SIGNIFICANCE: Online training for residents is a viable option to address knowledge deficits in TUD. (Am J Addict 2019;00:1-8). PMID: 30993797 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - April 16, 2019 Category: Addiction Authors: Williams JM, Poulsen R, Chaguturu V, Tobia A, Palmeri B Tags: Am J Addict Source Type: research

Worries About Discontinuing Buprenorphine Treatment: Scale Development and Clinical Correlates.
Abstract BACKGROUND AND OBJECTIVES: Despite the benefits of maintenance buprenorphine treatment for opioid use disorder (OUD), many individuals report an interest in discontinuing the medication, while also expressing worries about tapering. The purpose of this study was to develop a measure of worries about buprenorphine discontinuation ("Off Bupe") and determine the demographic and clinical characteristics associated with these worries. METHODS: Between May 2017 and May 2018, we surveyed adults in an outpatient primary care buprenorphine program (n = 138). Reliability and validity of...
Source: American Journal on Addictions - April 16, 2019 Category: Addiction Authors: Stein MD, Conti MT, Herman DS, Anderson BJ, Bailey GL, Noppen DV, Abrantes AM Tags: Am J Addict Source Type: research

Brief report: Characterization of marijuana use in us college students by state marijuana legalization status as reported to an online survey.
The objective was to investigate use characteristics among college students. METHODS: The RADARS® System College Survey Program surveyed individuals in a university, technical or online school. This was a secondary analysis of existing data. RESULTS: Seven thousand one hundred five students were enrolled,
Source: American Journal on Addictions - March 22, 2019 Category: Addiction Authors: Wang GS, Haynes C, Besharat A, Lait ML, Green JL, Dart RC, Roosevelt G Tags: Am J Addict Source Type: research

Rapid micro-induction of buprenorphine/naloxone for opioid use disorder in an inpatient setting: A case series.
CONCLUSIONS: These cases provide an alternative method for starting buprenorphine/naloxone that offers unique benefits compared to protocols previously described in the literature. SCIENTIFIC SIGNIFICANCE: This method can be used to minimize barriers to opioid agonist therapy. (Am J Addict 2019;XX:1-4). PMID: 30901127 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - March 22, 2019 Category: Addiction Authors: Klaire S, Zivanovic R, Barbic SP, Sandhu R, Mathew N, Azar P Tags: Am J Addict Source Type: research

The potency of social versus drug rewards.
PMID: 30802344 [PubMed - as supplied by publisher] (Source: American Journal on Addictions)
Source: American Journal on Addictions - February 25, 2019 Category: Addiction Authors: AAAP Scientific Content Contributor Tags: Am J Addict Source Type: research

The CASTRO study: Unsafe sexual behaviors and illicit drug use among gay and bisexual men who use anabolic steroids.
Abstract BACKGROUND AND OBJECTIVES: The majority of anabolic androgenic steroid (AAS) studies have focused on the general male population. Approximately 15% of gay or bisexual men are seropositive for HIV and many AASs are administered via injection. Thus, AAS use among gay and bisexual men likely poses a greater risk of spreading infectious disease. Gay and bisexual men who use AAS were compared with non-users regarding self-reported seropositivity for HIV and hepatitis B and C, sexual behaviors and injection practices, illicit drug and alcohol use, and psychiatric disorders. METHODS: The CASTRO (Castro Anab...
Source: American Journal on Addictions - February 6, 2019 Category: Addiction Authors: Ip EJ, Doroudgar S, Shah-Manek B, Barnett MJ, Tenerowicz MJ, Ortanez M, Pope HG Tags: Am J Addict Source Type: research