Multi-session anodal tDCS enhances the effects of postural training on balance and postural stability in older adults with high fall risk: Primary motor cortex versus cerebellar stimulation
Postural control impairment is a key target for rehabilitation of older adults with high fall risk. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 13, 2018 Category: Neurology Authors: Mohaddeseh Hafez Yosephi, Fatemeh Ehsani, Maryam Zoghi, Shapour Jaberzadeh Source Type: research

Effective deep brain stimulation of intractable tinnitus: A case study
Tinnitus, the hearing of sound when no external sound is present, may cause severe distress and impair quality of life in 0.5-3% of the adult population [1]. Chronic severe tinnitus is often accompanied by severe insomnia, anxiety and depression, eventually resulting in suicide and requests for euthanasia [2]. For these patients, few treatment options are currently available and 20% remains affected despite treatment [1]. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 12, 2018 Category: Neurology Authors: Eva Dijkstra, Martijn Figee, Damiaan Denys, P. Richard Schuurman Source Type: research

Case Report of Syncope during a Transcranial Direct Current Stimulation Experiment in a Healthy Adult Participant
Dear Editor: (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 2, 2018 Category: Neurology Authors: Flora Li, Sheryl Ball, Benjamin Katz, Alec Smith Source Type: research

Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Improving Oromotor Function in Newborns
Infants born prematurely or who suffer a global hypoxic ischemic encephalopathy (HIE) are at high risk for motor problems, which manifest as feeding delays during their hospital admission. Oromotor dyscoordination is common in these infants, and feeding difficulty is the primary reason for delayed discharge [1]. Many infants who do not master this motor skill before term age (40-42 weeks gestation) will receive a gastrostomy tube (G-tube) for direct gastric feeding. Furthermore, feeding difficulties in infants are associated with later language delays, even in the absence of gross motor impairment [2]. (Source: BRAIN STIMU...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 2, 2018 Category: Neurology Authors: Bashar W. Badran, Dorothea D. Jenkins, William H. Devries, Morgan Dancy, Philipp M. Summers, Georgia M. Mappin, Henry Bernstein, Marom Bikson, Patricia Cocker-Bolt, Mark S. George Source Type: research

Deep Brain Stimulation Electrode Insertion and Depression: Patterns of Activity and Modulation by Analgesics
An initial antidepressant effect when using deep brain stimulation (DBS) of the subcallosal area of the cingulate cortex (Cg25) to treat resistant depression that could be the result of electrode insertion has been described. We previously showed that electrode insertion into the infralimbic cortex (ILC; the Cg25 rodent correlate) provokes a temporally limited antidepressant-like effect that is counteracted by non-steroidal anti-inflammatory drugs, such as those routinely used for pain relief. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - July 2, 2018 Category: Neurology Authors: L. Perez-Caballero, M.L. Soto-Montenegro, M. Hidalgo-Figueroa, J.A. Mico, M. Desco, E. Berrocoso Source Type: research

Masthead
(Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 23, 2018 Category: Neurology Source Type: research

Editorial Board
(Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 23, 2018 Category: Neurology Source Type: research

Table of Contents
(Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 23, 2018 Category: Neurology Source Type: research

Information for Authors
(Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 23, 2018 Category: Neurology Source Type: research

Sensorimotor mu-alpha power is positively related to corticospinal excitability
Alpha (8 –14 Hz) oscillatory power is linked to cortical excitability and corresponding modulations of sensory evoked potentials and perceptual detection performance. In somatosensory cortex (S1), negative linear and inverted U-shape relationships exist, whereas its effect on the primary motor cortex (M1 ) is hardly known. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 19, 2018 Category: Neurology Authors: Miriam Thies, Christoph Zrenner, Ulf Ziemann, Til Ole Bergmann Source Type: research

Sensorimotor mu-power is positively related to corticospinal excitability
Alpha (8 –14 Hz) oscillatory power is linked to cortical excitability and corresponding modulations of sensory evoked potentials and perceptual detection performance. In somatosensory cortex (S1), negative linear and inverted U-shape relationships exist, whereas its effect on the primary motor cortex (M1 ) is hardly known. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 19, 2018 Category: Neurology Authors: Miriam Thies, Christoph Zrenner, Ulf Ziemann, Til Ole Bergmann Source Type: research

Transient aphasia after right-unilateral ultrabrief electroconvulsive therapy: A case report
We present a unique case of a 35-year old woman, who underwent an outpatient ECT session at our department, followed by a short span of aphasic symptoms, the extent of which were monitored clinically and via the czech version of the Minnesota aphasia screening test. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 19, 2018 Category: Neurology Authors: J. Buday, J. Albrecht, T. Mares, J. Raboch, M. Anders Source Type: research

Modulation of cortical responses by transcranial direct current stimulation of dorsolateral prefrontal cortex: a resting-state EEG and TMS-EEG study
Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique with potential for cost-effective therapeutic neuromodulation. Although positive therapeutic effects were found by stimulating the dorsolateral prefrontal cortex (DLPFC), few studies have investigated physiological effects of DLPFC-tDCS. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 16, 2018 Category: Neurology Authors: Pedro Caldana Gordon, Christoph Zrenner, Debora Desideri, Paolo Belardinelli, Brigitte Zrenner, Andr é Russowsky Brunoni, Ulf Ziemann Source Type: research

Effects of Single versus Dual-Site High-Definition Transcranial Direct Current Stimulation (HD-tDCS) on Cortical Reactivity and Working Memory Performance in Healthy Subjects
Previous research has typically focussed on the neuromodulatory effects of direct currents applied over single regions of the cortex. However, complex processes such as working memory (WM) strongly rely on activations across a wider neural network and therefore might benefit from stimulation administered over multiple cortical targets. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 16, 2018 Category: Neurology Authors: Aron T. Hill, Nigel C. Rogasch, Paul B. Fitzgerald, Kate E. Hoy Source Type: research

Tragus or cymba conchae? Investigating the anatomical foundation of transcutaneous auricular vagus nerve stimulation (taVNS)
We thank Burger and Verkuil [1] for bringing attention to the only published cadaver ear dissection studies in the literature, published in 2002 by Peuker and Filler [2]. This cadaver study is indeed important, and has fueled the increased interest in modulating the auricular branch of the vagus nerve (ABVN). Researchers clearly want to know which ear target is optimal for taVNS – tragus or cymba conchae? Burger and Verkuil have found and investigated an apparent discrepancy in Peuker and Filler's work, and then contacted Prof. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 6, 2018 Category: Neurology Authors: Bashar W. Badran, Joshua C. Brown, Logan T. Dowdle, Oliver J. Mithoefer, Nicholas T. LaBate, James Coatsworth, William H. DeVries, Christopher W. Austelle, Lisa M. McTeague, Alfred Yu, Marom Bikson, Dorothea D. Jenkins, Mark S. George Source Type: research

Repetitive Transcranial Magnetic Stimulation of the Left Dorsolateral Prefrontal Cortex May Improve Symptoms of Anhedonia in Individuals with Cocaine Use Disorder: A Pilot Study
Cocaine use disorder (CUD) is characterized by positive symptoms, such as craving, and negative affective states, all of which may drive drug taking and relapse. One prominent symptom that is part of the negative affective states is termed anhedonia, and is defined as an impaired ability to experience pleasure from natural rewards such as food, water, sex, and nurturing. From a neurobiological standpoint, disruption in dopaminergic mesocorticolimbic reward processing plays an important role in the development of anhedonia [1]. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 5, 2018 Category: Neurology Authors: Mauro Pettorruso, Primavera Alessandra Spagnolo, Lorenzo Leggio, Luigi Janiri, Massimo Di Giannantonio, Luigi Gallimberti, Antonello Bonci, Giovanni Martinotti Source Type: research

Efficacy of Repetitive Transcranial Magnetic Stimulation for Tourette syndrome: A Systematic Review and Meta-Analysis
While previous studies have investigated the effect of repetitive transcranial magnetic stimulation (rTMS) in treating Tourette syndrome (TS), the results remain inconclusive. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - June 5, 2018 Category: Neurology Authors: Chih-Wei Hsu, Liang-Jen Wang, Pao-Yen Lin Source Type: research

Anodal transcranial direct current stimulation affects auditory cortex plasticity in normal-hearing and noise-exposed rats
Transcranial direct current stimulation (tDCS) is a non-invasive tool capable to modulate cortical functions by affecting neuronal excitability and synaptic plasticity. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 30, 2018 Category: Neurology Authors: Fabiola Paciello, Maria Vittoria Podda, Rolando Rolesi, Sara Cocco, Laura Petrosini, Diana Troiani, Anna Rita Fetoni, Gaetano Paludetti, Claudio Grassi Source Type: research

Repetitive transcranial magnetic stimulation of the right parietal cortex for comorbid generalized anxiety disorder and insomnia: a randomized, double-blind, sham-controlled pilot study
Repetitive transcranial magnetic stimulation (rTMS) has been considered to be a promising technique for the treatment of neuropsychiatric disorders. However, little is known about the effectiveness of rTMS in the treatment of generalized anxiety disorder (GAD). Moreover, treatment data on comorbid GAD and insomnia remain lacking. The aim of this study was to examine the therapeutic effects of 1  Hz rTMS applied over the right parietal lobe on both anxiety and insomnia symptoms in patients with comorbid GAD and insomnia. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 29, 2018 Category: Neurology Authors: Zhaoyang Huang, Yue Li, Matt T. Bianchi, Shuqin Zhan, Fengying Jiang, Ning Li, Yan Ding, Yue Hou, Li Wang, Quping Ouyang, Yuping Wang Source Type: research

MAGIC: An open-source MATLAB toolbox for external control of transcranial magnetic stimulation devices
Transcranial magnetic stimulation (TMS) is widely used in basic and clinical research. As long as standard protocols with fixed-stimulation parameters are used, it is sufficient to pre-define those parameters manually via the control interface of the TMS device. However, there are two scenarios for which stimulation parameters need to be changed automatically from trial-to-trial: a priori randomization (e.g., intermingling single- and paired-pulse conditions to prevent order effects) and ad hoc adjustment (e.g., iteratively adjusting stimulation parameters based on past events or current brain state). (Source: BRAIN STIMUL...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 26, 2018 Category: Neurology Authors: Forough Habibollahi Saatlou, Nigel C. Rogasch, Mana Biabani, Nicolas A. McNair, Steven D. Pillen, Tom R. Marshall, Til O. Bergmann Source Type: research

Early relapse (ER) transcranial magnetic stimulation (TMS) in treatment resistant major depression
There is interest in using TMS to keep patients with severe relapsing depression as well as possible, once remission has been achieved. This has been conceptualized as ‘maintaining’ the remission. One protocol employs series of 5 TMS sessions over 3 or 5 days, at about monthly intervals. We have suggested this practice is better conceptualized as early relapse (ER) TMS. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 22, 2018 Category: Neurology Authors: Saxby Pridmore, Sheila Erger, Marzena Rybak, Erin Kelly, Tamara May Source Type: research

Extradural motor cortex stimulation improves gait, speech, and language in a patient with pure akinesia
Pure akinesia with gait freezing (PAGF) is a variant of progressive supranuclear palsy, poorly responsive to pharmacological treatment and mainly characterized by prominent freezing of gait and dysarthria. Extradural motor cortex stimulation (EMCS) is a safe neurosurgical procedure [1], which may improve axial motorsymptoms of Parkinson's disease (PD) [2] and might represent a therapeutic option in patients with movements disorders not eligible for deep brain stimulation (DBS) [3,4]. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 22, 2018 Category: Neurology Authors: Carla Piano, Alfonso Fasano, Antonio Daniele, Daniela Di Giuda, Marco Ciavarro, Tommaso Tufo, Massimiliano Zinno, Anna Rita Bentivoglio, Beatrice Cioni Source Type: research

Whole-brain low-intensity pulsed ultrasound therapy markedly improves cognitive dysfunctions in mouse models of dementia - Crucial roles of endothelial nitric oxide synthase-
Therapeutic focused-ultrasound to the hippocampus has been reported to exert neuroprotective effects on dementia. In the present study, we examined whether the whole-brain LIPUS (low-intensity pulsed ultrasound) therapy is effective and safe in 2 mouse models of dementia (vascular dementia, VaD and Alzheimer's disease, AD), and if so, to elucidate the common underlying mechanism(s) involved. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 21, 2018 Category: Neurology Authors: Kumiko Eguchi, Tomohiko Shindo, Kenta Ito, Tsuyoshi Ogata, Ryo Kurosawa, Yuta Kagaya, Yuto Monma, Sadamitsu Ichijo, Sachie Kasukabe, Satoshi Miyata, Takeo Yoshikawa, Kazuhiko Yanai, Hirofumi Taki, Hiroshi Kanai, Noriko Osumi, Hiroaki Shimokawa Source Type: research

BDNF plasma levels and genotype in depression and the response to electroconvulsive therapy
Brain derived neurotrophic factor (BDNF) has been implicated in the pathophysiology of depression and the antidepressant response. Electroconvulsive therapy (ECT) is reported to increase BDNF levels in blood, though only a small number of studies have been conducted to date. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 18, 2018 Category: Neurology Authors: Karen M. Ryan, Ross Dunne, Declan M. McLoughlin Source Type: research

Electrical Stimulation of the Midbrain Excites the Auditory Cortex Asymmetrically
Auditory midbrain implant users cannot achieve open speech perception and have limited frequency resolution. It remains unclear whether the spread of excitation contributes to this issue and how much it can be compensated by current focusing, which is an effective approach in cochlear implants. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 17, 2018 Category: Neurology Authors: Gunnar Lennart Qua ß, Simone Kurt, Jannis Hildebrandt, Andrej Kral Source Type: research

Predictive value of dorso-lateral prefrontal connectivity for rTMS response in treatment-resistant depression: A brain perfusion SPECT study
Previous clinical trials have suggested that repetitive transcranial magnetic stimulation (rTMS) has a significant antidepressant effect in patients with treatment resistant depression (TRD). However, results remain heterogeneous with many patients without effective response. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 17, 2018 Category: Neurology Authors: Rapha ëlle Richieri, Antoine Verger, Laurent Boyer, Mohamed Boucekine, Anthony David, Christophe Lançon, Michel Cermolacce, Eric Guedj Source Type: research

Action potential initiation, propagation, and cortical invasion in the hyperdirect pathway during subthalamic deep brain stimulation
High frequency ( ∼130 Hz) deep brain stimulation (DBS) of the subthalamic region is an established clinical therapy for the treatment of late stage Parkinson's disease (PD). Direct modulation of the hyperdirect pathway, defined as cortical layer V pyramidal neurons that send an axon collateral to the subthalamic nucleus (STN), has emerged as a possible component of the therapeutic mechanisms. However, numerous questions remain to be addressed on the basic biophysics of hyperdirect pathway stimulation. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 12, 2018 Category: Neurology Authors: Ross W. Anderson, AmirAli Farokhniaee, Kabilar Gunalan, Bryan Howell, Cameron C. McIntyre Source Type: research

Brain stimulation patterns emulating endogenous thalamocortical input to parvalbumin-expressing interneurons reduce nociception in mice
The bursting pattern of thalamocortical (TC) pathway dampens nociception. Whether brain stimulation mimicking endogenous patterns can engage similar sensory gating processes in the cortex and reduce nociceptive behaviors remains uninvestigated. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 11, 2018 Category: Neurology Authors: Yeowool Huh, Dahee Jung, Taeyoon Seo, Sukkyu Sun, Su Hyun Kim, Hyewhon Rhim, Sooyoung Chung, Chong-Hyun Kim, Youngwoo Kwon, Marom Bikson, Yong-an Chung, Jeansok J. Kim, Jeiwon Cho Source Type: research

Histopathology after microelectrode recording and twelve years of deep brain stimulation
Despite the widespread use of deep brain stimulation (DBS), studies on the histological alterations induced by the DBS electrode remain relatively scarce. Typical findings include fibrous sheaths of 5-25 μm surrounding the electrode track, a chronic inflammation with reactive astrocytes, multinucleated giant cells, macrophages, mononuclear leucocytes and T-lymphocytes, fibrillary gliosis and Rosenthal fibers [1,2]. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 9, 2018 Category: Neurology Authors: Philippe De Vloo, Dietmar Thal, Kris van Kuyck, Bart Nuttin Source Type: research

Potentiating Paired Corticospinal-Motoneuronal Plasticity after Spinal Cord Injury
Paired corticospinal-motoneuronal stimulation (PCMS) increases corticospinal transmission in humans with chronic incomplete spinal cord injury (SCI).Objective/Hypothesis: Here, we examine whether increases in the excitability of spinal motoneurons, by performing voluntary activity, could potentiate PCMS effects on corticospinal transmission. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 9, 2018 Category: Neurology Authors: Karen L. Bunday, M.A. Urbin, Monica A. Perez Source Type: research

Report of one confirmed generalized seizure and one suspected partial seizure induced by deep continuous theta burst stimulation of the right operculo-insular cortex
Dear Editor, (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 8, 2018 Category: Neurology Authors: C édric Lenoir, Maxime Algoet, Camille Vanderclausen, André Peeters, Susana Ferrao Santos, André Mouraux Source Type: research

TMS Evoked N100 Reflects Local GABA and Glutamate Balance
Animal studies suggest that synchronized electrical activities in the brain are regulated by the primary inhibitory and excitatory neurotransmitters gamma-aminobutyric acid (GABA) and glutamate, respectively. Identifying direct evidence and measure that this same basic chemical-electrical neuroscience principle operates in the human brains is critical for translation of neuroscience to pathological research. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 4, 2018 Category: Neurology Authors: Xiaoming Du, Laura M. Rowland, Ann Summerfelt, S. Andrea Wijtenburg, Joshua Chiappelli, Krista Wisner, Peter Kochunov, Fow-Sen Choa, L. Elliot Hong Source Type: research

Increased short-interval intracortical inhibition in un-medicated patients with schizophrenia
Schizophrenia is associated with changes in inhibitory and facilitatory brain networks which can be assessed by motor cortex excitability (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 4, 2018 Category: Neurology Authors: Martin Schecklmann, Carmen Weidler, Peter Eichhammer, G öran Hajak, Berthold Langguth Source Type: research

Tolerability and blinding of 4x1 High-Definition transcranial direct current stimulation (HD-tDCS) at two and three milliamps
Transcranial direct current stimulation (tDCS) is an in-demand form of neuromodulation generally regarded as safe and well tolerated. However, few studies have examined the safety, tolerability, or blinding of High Definition (HD-) tDCS, especially in older adults and at stimulation intensities of 2 milliamps (mA) or greater. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 3, 2018 Category: Neurology Authors: Jaclyn Reckow, Annalise Rahman-Filipiak, Sarah Garcia, Stephen Schlaefflin, Oliver Calhoun, Alexandre F. DaSilva, Marom Bikson, Benjamin M. Hampstead Source Type: research

Testing assumptions on prefrontal transcranial direct current stimulation: Comparison of electrode montages using multimodal fMRI
Transcranial direct current stimulation (tDCS) of the prefrontal cortex (PFC) has been widely applied in cognitive neurosciences and advocated as a therapeutic intervention, e.g. in major depressive disorder. Although several targets and protocols have been suggested, comparative studies of tDCS parameters, particularly electrode montages and their cortical targets, are still lacking. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 3, 2018 Category: Neurology Authors: Jana W örsching, Frank Padberg, Stephan Goerigk, Irmgard Heinz, Christine Bauer, Christian Plewnia, Alkomiet Hasan, Birgit Ertl-Wagner, Daniel Keeser Source Type: research

Randomized controlled trial of home-based 4-week tDCS in chronic minimally conscious state
Patients with chronic disorders of consciousness face a significant lack of treatment options. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - May 2, 2018 Category: Neurology Authors: G éraldine Martens, Nicolas Lejeune, Anthony Terrence O’Brien, Felipe Fregni, Charlotte Martial, Sarah Wannez, Steven Laureys, Aurore Thibaut Source Type: research

What intensity of deep repetitive transcranial magnetic stimulation is necessary to remit treatment resistant depression
Background: dTMS for treatment resistant depression uses high frequency pulses to stimulate the prefrontal cortex at an intensity of 120% of the resting motor threshold (120MT). Is 120MT necessary to achieve remission or are lower intensities efficacious? Intensity and efficacy data from the active arm of the Brainsway multicenter clinical trial were analyzed. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 28, 2018 Category: Neurology Authors: Roman Gersner, Aron Tendler, Abraham Zangen, Yiftach Roth Source Type: research

Left dorsolateral prefrontal cortex rTMS in alleviating MTBI related headaches and depressive symptoms
This study assessed the effect of repetitive transcranial magnetic stimulation (rTMS) at the left prefrontal cortex in reducing MTBI-HA and co-morbid neuropsychological dysfunctions. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 28, 2018 Category: Neurology Authors: Albert Leung, Valerie Metzger-Smith, Yifan He, James Cordero, Brandon Ehlert, David Song, Shahrokh Golshan, Alice Tsai, Michael Vaninetti, Thomas Rutledge, Gregory Polston, Robert Sheu, Roland Lee Source Type: research

Transcranial magnetic stimulation for the treatment of major depressive disorder in adolescents and young adults
Objective: To assess the effectiveness of TMS in Adolescents and Young Adults with MDD (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 28, 2018 Category: Neurology Authors: Andrea Carlsen, Jill Mandel, Gregory Toso Source Type: research

Alternative antidepressant deep transcranial magnetic stimulation protocols
Background: The remission rate for patients with pharmacotherapy resistant depression who undergo standard deep repetitive transcranial magnetic stimulation (dTMS) is almost 50%. This protocol consists of twenty daily treatments utilizing high-frequency (18Hz, 1980 pulses) stimulation to the left PFC (L-PFC). Its remission rate is second only to electroconvulsive therapy, which has significant cognitive side effects and poor durability. Nevertheless, alternative treatments for non-responders should be explored. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 28, 2018 Category: Neurology Authors: Aron Tendler, Elyssa Sisko, Noam Barnea-Ygael Source Type: research

Sequential L-PFC, dmPFC-ACC, accelerated intermittent theta burst dTMS for suicidal highly treatment resistant depression patients
Introduction: Depressed, suicidal patients who failed pharmacologic and brain stimulation protocols have significant hopelessness about future treatment, making a four-week treatment protocol particularly challenging. We treated this challenging population with accelerated intermittent theta burst (iTBS) to the left PFC (L-PFC) and dorsomedial prefrontal cortex-anterior cingulate cortex (dmPFC-ACC), two regions associated with antidepressant deep rTMS(dTMS) response. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 28, 2018 Category: Neurology Authors: Aron Tendler, Elyssa Sisko, Noelia Rodriguez, Sky Corbett-Methot, Jackie Sutton-DeBord, Jeanette Brown, Nolan Williams Source Type: research

Clinical efficacy of transcranial magnetic stimulation for the treatment of major depression in an outpatient setting
Abstract (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 28, 2018 Category: Neurology Authors: Daphne Antillon, Noel Barragan, Jessica Jenkins, Jane Hutton, Todd Hutton Source Type: research

Low frequency rTMS ameliorates akathisia: Case report
Introduction: Akathisia is a common side effect of psychotropic medications, including selective serotonin reuptake inhibitors (SSRI). Recently, a mechanism in which compensatory increased noradrenergic activity is triggered by dopamine reduction has been proposed1. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 28, 2018 Category: Neurology Authors: Jos é Luis Guerrero Solano, Elena Molina Pacheco, Julio I. Prieto Montalvo, Alejandro Marfil Rivera Source Type: research

Case report: dTMS and improvement of kidney functions in a CKD patient
This is to report a case-study of a patient with stage 3b Chronic Kidney Disease (CKD) as well as Major Depressive Disorder (MDD) to examine the relationship between the brain and the renal system. This case of significant kidney function improvement following the standard Transcranial Magnetic Stimulation (TMS) protocol used for the treatment of MDD may suggest a role of TMS in the functional improvement of CKD and requires our attention to other therapeutic effects of TMS on the human body. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 28, 2018 Category: Neurology Authors: Jacek Maitan, Guohua Xia, Zahida Tayyib, Brian Carrie Source Type: research

Effectiveness of adjunctive rTMS for treatment resistance depression in a community population
Objective: A prospective observational study of the effectiveness of adjunctive repetitive transcranial magnetic stimulation (rTMS) for treating refractory unipolar major depressive disorder (MDD) in a private practice setting. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 28, 2018 Category: Neurology Authors: Jesse Bastiaens, Ramotse Saunders, Mohamed Esuf, Richard Bermudes Source Type: research

Unusual or possibly dangerous TMS side effects, a case series
We present TMS patients having issues with dental braces, a rise in measured intraocular pressure, an atypical seizure and syncope during TMS. This is the first report of increased intraocular pressure with TMS. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 28, 2018 Category: Neurology Authors: Kevin M. Kinback Source Type: research

Left prefrontal cortex high frequency deep TMS for neuropsychiatric symptoms of lyme disease: Case report
Objective: To report potential efficacy in improving cognitive impairment found in patients with Lyme disease. This case also serves as developing insight into the diversity of Deep Transcranial Magnetic Stimulation. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 28, 2018 Category: Neurology Authors: Manish Sheth, Shashita Inamdar, Newshaw Karkhanehchin, Brandyn Roach, Madison Walsh, Allison Dehart Source Type: research

Repetitive Transcranial Magnetic Stimulation (rTMS) application in cognitive deficits after Traumatic Brain Injury (TBI)/concussion
The objective of this study is to review current literature for the efficacy of Repetitive Transcranial Magnetic Stimulation (rTMS) treatment for cognitive deficits after Traumatic Brain Injury (TBI)/concussion. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 28, 2018 Category: Neurology Authors: Mohammed Ahmed, Kristoffer Nissinen, Jaimie Long, Samreen Haque Source Type: research

rTMS for major depression: Treatment outcomes at an academic medical center
Dr. Cristancho receives research support from NIMH 3R34MH101433-01A1, The Barnes-Jewish Hospital Foundation and the Center for Brain Research in Mood Disorders at Washington University. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 28, 2018 Category: Neurology Authors: Pilar Cristancho, Nicholas T. Trapp, Shan H. Siddiqi, David Dixon, Eric J. Lenze Source Type: research

TBI during a course of TMS - A case report
Introduction: There is no published guidance on TBI during a course of TMS. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 28, 2018 Category: Neurology Authors: Ramotse Saunders, Richard Bermudes Source Type: research