Chronic Obstructive Pulmonary Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Lung fibroblast-derived extracellular vesicles and soluble factors alleviate elastase-induced lung injury
In conclusion, this study highlights the therapeutic potential of both lung fibroblast-derived EV- and SF-enriched concentrates for the treatment of lung injury and emphysema.PMID:38677537 | DOI:10.1016/j.ejphar.2024.176612 (Source: European Journal of Pharmacology)
Source: European Journal of Pharmacology - April 27, 2024 Category: Drugs & Pharmacology Authors: Luke van der Koog Myrthe J Boerrigter Iris C Gorter Reinoud Gosens Anika Nagelkerke Source Type: research

Melatonin improves influenza virus infection-induced acute exacerbation of COPD by suppressing macrophage M1 polarization and apoptosis
CONCLUSIONS: These findings suggested that melatonin inhibited IAV infection, improved lung function and lung damages of AECOPD via suppressing IL-1β/STAT1-driven macrophage M1 polarization and apoptosis in a MTs-dependent manner. Melatonin may be considered as a potential therapeutic agent for influenza virus infection-induced AECOPD.PMID:38678295 | PMC:PMC11056066 | DOI:10.1186/s12931-024-02815-0 (Source: Respiratory Care)
Source: Respiratory Care - April 27, 2024 Category: Respiratory Medicine Authors: Meng-Meng Xu Jia-Ying Kang Qiu-Yan Wang Xing Zuo Yuan-Yuan Tan Yuan-Yuan Wei Da-Wei Zhang Ling Zhang Hui-Mei Wu Guang-He Fei Source Type: research

Respiratory symptoms and outcomes among cigar smokers: findings from the Population Assessment of Tobacco and Health (PATH) study waves 2-5 (2014-2019)
CONCLUSIONS: This study provides evidence that cigar smokers or dual smokers of cigars and cigarettes have greater odds of FIRS, asthma, and uncontrolled asthma and that new incidence of FIRS is higher among any cigar smokers compared to never cigar or cigarette smokers. Understanding health impacts associated with cigar use provides information for supporting policy development, as well as for designing clinical interventions focused on smoking cessation for cigars.PMID:38678212 | PMC:PMC11055341 | DOI:10.1186/s12931-024-02818-x (Source: Respiratory Care)
Source: Respiratory Care - April 27, 2024 Category: Respiratory Medicine Authors: Eva Sharma Kristin Lauten Katarzyna A Zebrak Kathryn C Edwards Samantha VanEtten Adam F Benson Cristine D Delnevo Daniela Marshall Heather L Kimmel Kristie A Taylor Maansi Bansal-Travers Andrew Hyland K Michael Cummings Source Type: research

Elastolysis in COPD: a Target for Therapy
(Source: Lung)
Source: Lung - April 27, 2024 Category: Respiratory Medicine Source Type: research

Melatonin improves influenza virus infection-induced acute exacerbation of COPD by suppressing macrophage M1 polarization and apoptosis
Influenza A viruses (IAV) are extremely common respiratory viruses for the acute exacerbation of chronic obstructive pulmonary disease (AECOPD), in which IAV infection may further evoke abnormal macrophage pol... (Source: Respiratory Research)
Source: Respiratory Research - April 27, 2024 Category: Respiratory Medicine Authors: Meng-Meng Xu, Jia-Ying Kang, Qiu-Yan Wang, Xing Zuo, Yuan-Yuan Tan, Yuan-Yuan Wei, Da-Wei Zhang, Ling Zhang, Hui-Mei Wu and Guang-He Fei Tags: Original Article Source Type: research

An example of ventilatory limitation during cardiopulmonary exercise testing in a patient with COPD
A 64-year-old gentleman with obesity and moderate COPD attended for further evaluation of ongoing dyspnoea despite treatment with dual long acting bronchodilators. A cardiopulmonary exercise test (CPET) was performed, which demonstrated reduced peak work and oxygen consumption with evidence of dynamic hyperinflation, abnormal gas exchange and ventilatory limitation despite cardiac reserve. The CPET clarified the physiological process underpinning the patient's dyspnoea and limiting the patient's activities. This, in turn, helped the clinician tailor the patient's management plan. AbstractA 64-year-old obese gentleman atten...
Source: Respirology Case Reports - April 26, 2024 Category: Respiratory Medicine Authors: Claude S. Farah, Leigh M. Seccombe, Greg G. King, David G. Chapman, Charles G. Irvin Tags: CASE REPORT Source Type: research

Corrigendum to: Negligible effect of vitamin D supplementation on exacerbation in patients with chronic obstructive pulmonary disease: meta-analysis
Biochem Med (Zagreb). 2024 Jun 15;34(2):021201. doi: 10.11613/BM.2024.021201.ABSTRACT[This corrects the article , PMID: 37841773.].PMID:38665869 | PMC:PMC11042563 | DOI:10.11613/BM.2024.021201 (Source: Biochemia Medica)
Source: Biochemia Medica - April 26, 2024 Category: Biochemistry Authors: Ye Hua Ting Jiang Jiangyi Feng Mi Zou Source Type: research

How to Enhance the Diagnosis of Early Stages of Chronic Obstructive Pulmonary Disease (COPD)? The Role of Mobile Spirometry in COPD Screening and Diagnosis-A Systematic Review
Adv Respir Med. 2024 Mar 27;92(2):158-174. doi: 10.3390/arm92020018.ABSTRACTCOPD is the third leading cause of death worldwide. Its diagnosis can be made with spirometry, which is underused due to its limited accessibility. Portable spirometry holds promise for enhancing the efficacy of COPD diagnoses. The study aimed to estimate COPD prevalence diagnosed with a portable spirometer in high-risk patients and compare it with COPD prevalence based on data from conventional, on-site spirometry. We also evaluated the strategy of a proactive approach to identify COPD in high-risk individuals. We conducted a systematic review of ...
Source: Adv Data - April 26, 2024 Category: Epidemiology Authors: Piotr Jankowski Katarzyna Mycroft Katarzyna G órska Piotr Korczy ński Rafa ł Krenke Source Type: research

Joint effect of long-term exposure to ambient air pollution on the prevalence of chronic obstructive pulmonary disease using the Korea National Health and Nutrition Examination Survey 2010-2019
CONCLUSIONS: Long-term exposure to air pollutants, both individually and jointly, was associated with an increased risk of developing COPD, particularly restrictive lung disease. Our findings highlight the importance of comprehensively assessing exposure to various air pollutants in relation to COPD.PMID:38670507 | DOI:10.1016/j.chemosphere.2024.142137 (Source: Chemosphere)
Source: Chemosphere - April 26, 2024 Category: Chemistry Authors: Eunjin Kwon Taiyue Jin Young-Ah You Byungmi Kim Source Type: research

ZC3H13 promotes ITGA6 m < sup > 6 < /sup > A modification for chronic obstructive pulmonary disease progression
In conclusion, targeting ZC3H13/ITGA6 could be an underlying therapeutic approach for treating COPD.PMID:38670474 | DOI:10.1016/j.cellsig.2024.111190 (Source: Cellular Signalling)
Source: Cellular Signalling - April 26, 2024 Category: Cytology Authors: Bin Xie Ziyu Dai Chen Jiang Xufan Gao Shasha Yang Meijuan Peng Qiong Chen Xi Chen Source Type: research

Development of two questionnaires for the assessment of knowledge and self-management in patients with chronic-obstructive pulmonary disease (COPD)
DISCUSSION: The questionnaires on knowledge and self-management in patients with COPD could be used in outpatient settings, including by non-medical staff, in order to quickly identify and correct deficits or as a reason to recommend training programs. The short versions and the analogue scales for self-assessment can give at least first hints. Potentially, training programs should focus more on promoting the coherence of knowledge through better understanding, as this presumably favors long-term knowledge. Older patients and those with a low level of education appear to be particularly in need of specially adapted trainin...
Source: Pneumologie - April 26, 2024 Category: Respiratory Medicine Authors: Carolina Fischer Rainald Fischer Anne-Marie Kirsten Rolf Holle Klaus Kl ütsch Cosmina Stoleriu Ralf G öres Konrad Schultz Kathrin Kahnert Peter Alter Dennis Nowak Rudolf J örres Source Type: research