Joint effect of long-term exposure to ambient air pollution on the prevalence of chronic obstructive pulmonary disease using the Korea National Health and Nutrition Examination Survey 2010-2019
CONCLUSIONS: Long-term exposure to air pollutants, both individually and jointly, was associated with an increased risk of developing COPD, particularly restrictive lung disease. Our findings highlight the importance of comprehensively assessing exposure to various air pollutants in relation to COPD.PMID:38670507 | DOI:10.1016/j.chemosphere.2024.142137 (Source: Chemosphere)
Source: Chemosphere - April 26, 2024 Category: Chemistry Authors: Eunjin Kwon Taiyue Jin Young-Ah You Byungmi Kim Source Type: research

ZC3H13 promotes ITGA6 m < sup > 6 < /sup > A modification for chronic obstructive pulmonary disease progression
In conclusion, targeting ZC3H13/ITGA6 could be an underlying therapeutic approach for treating COPD.PMID:38670474 | DOI:10.1016/j.cellsig.2024.111190 (Source: Cellular Signalling)
Source: Cellular Signalling - April 26, 2024 Category: Cytology Authors: Bin Xie Ziyu Dai Chen Jiang Xufan Gao Shasha Yang Meijuan Peng Qiong Chen Xi Chen Source Type: research

Corrigendum to: Negligible effect of vitamin D supplementation on exacerbation in patients with chronic obstructive pulmonary disease: meta-analysis
Biochem Med (Zagreb). 2024 Jun 15;34(2):021201. doi: 10.11613/BM.2024.021201.ABSTRACT[This corrects the article , PMID: 37841773.].PMID:38665869 | PMC:PMC11042563 | DOI:10.11613/BM.2024.021201 (Source: Biochemia Medica)
Source: Biochemia Medica - April 26, 2024 Category: Biochemistry Authors: Ye Hua Ting Jiang Jiangyi Feng Mi Zou Source Type: research

Development of two questionnaires for the assessment of knowledge and self-management in patients with chronic-obstructive pulmonary disease (COPD)
DISCUSSION: The questionnaires on knowledge and self-management in patients with COPD could be used in outpatient settings, including by non-medical staff, in order to quickly identify and correct deficits or as a reason to recommend training programs. The short versions and the analogue scales for self-assessment can give at least first hints. Potentially, training programs should focus more on promoting the coherence of knowledge through better understanding, as this presumably favors long-term knowledge. Older patients and those with a low level of education appear to be particularly in need of specially adapted trainin...
Source: Pneumologie - April 26, 2024 Category: Respiratory Medicine Authors: Carolina Fischer Rainald Fischer Anne-Marie Kirsten Rolf Holle Klaus Kl ütsch Cosmina Stoleriu Ralf G öres Konrad Schultz Kathrin Kahnert Peter Alter Dennis Nowak Rudolf J örres Source Type: research

Corrigendum to: Negligible effect of vitamin D supplementation on exacerbation in patients with chronic obstructive pulmonary disease: meta-analysis
Biochem Med (Zagreb). 2024 Jun 15;34(2):021201. doi: 10.11613/BM.2024.021201.ABSTRACT[This corrects the article , PMID: 37841773.].PMID:38665869 | PMC:PMC11042563 | DOI:10.11613/BM.2024.021201 (Source: Biochemia Medica)
Source: Biochemia Medica - April 26, 2024 Category: Biochemistry Authors: Ye Hua Ting Jiang Jiangyi Feng Mi Zou Source Type: research

Development of two questionnaires for the assessment of knowledge and self-management in patients with chronic-obstructive pulmonary disease (COPD)
DISCUSSION: The questionnaires on knowledge and self-management in patients with COPD could be used in outpatient settings, including by non-medical staff, in order to quickly identify and correct deficits or as a reason to recommend training programs. The short versions and the analogue scales for self-assessment can give at least first hints. Potentially, training programs should focus more on promoting the coherence of knowledge through better understanding, as this presumably favors long-term knowledge. Older patients and those with a low level of education appear to be particularly in need of specially adapted trainin...
Source: Pneumologie - April 26, 2024 Category: Respiratory Medicine Authors: Carolina Fischer Rainald Fischer Anne-Marie Kirsten Rolf Holle Klaus Kl ütsch Cosmina Stoleriu Ralf G öres Konrad Schultz Kathrin Kahnert Peter Alter Dennis Nowak Rudolf J örres Source Type: research

Pharmacokinetic Models for Inhaled Fluticasone Propionate and Salmeterol Xinafoate to Quantify Batch-to-Batch Variability
AbstractAdvair Diskus is an essential treatment for asthma and chronic obstructive pulmonary disease. It is a dry powder inhaler with a combination of fluticasone propionate (FP) and salmeterol xinafoate (SX). However, the pharmacokinetics (PK) batch-to-batch variability of the reference-listed drug (RLD) hindered its generic product development. This work developed the PK models for inhaled FP and SX that could represent potential batch variability. Two batches each of the reference and the test product (R1,R2,T1,T2) of Advair Diskus (100  μg FP/50 μg SX inhalation) were administered to 60 healthy subjects in a 4-peri...
Source: The AAPS Journal - April 26, 2024 Category: Drugs & Pharmacology Source Type: research

Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 Guidelines Reviewed
Open Respir Med J. 2024 Jan 10;18:e18743064279064. doi: 10.2174/0118743064279064231227070344. eCollection 2024.ABSTRACTThe Global Initiative for Chronic Obstructive Lung Disease (GOLD) report is an essential resource for all clinicians who strive to provide optimal care to patients with chronic obstructive lung disease (COPD). The annual report of GOLD makes few revisions and updates besides including data from the preceding year. At an interval, GOLD comes up with a significant modification in its guidelines, which is generally a major overhaul of the pre-existing guidelines. According to the latest 2023 updates, publishe...
Source: Respiratory Care - April 25, 2024 Category: Respiratory Medicine Authors: Munish Sharma Sushil Joshi Prakash Banjade Shekhar A Ghamande Salim Surani Source Type: research

Inappropriate Peak Inspiratory Flow Rate in the Patients with Stable Chronic Obstructive Pulmonary Disease in Korea
CONCLUSIONS: Prevalence of inappropriate PIFR among patients with COPD is 17.2% for aerosol device users and 42.1% for DPI users. Suboptimal PIFR correlates with female gender, shorter stature, lower weight and MVV in DPI users.PMID:38659389 | DOI:10.4046/trd.2023.0195 (Source: Respiratory Care)
Source: Respiratory Care - April 25, 2024 Category: Respiratory Medicine Authors: Seong Hwan Youn Hyun Jung Kim Jae Seok Park Sun Hyo Park Yong Shik Kwon Mi-Ae Kim Source Type: research

Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 Guidelines Reviewed
Open Respir Med J. 2024 Jan 10;18:e18743064279064. doi: 10.2174/0118743064279064231227070344. eCollection 2024.ABSTRACTThe Global Initiative for Chronic Obstructive Lung Disease (GOLD) report is an essential resource for all clinicians who strive to provide optimal care to patients with chronic obstructive lung disease (COPD). The annual report of GOLD makes few revisions and updates besides including data from the preceding year. At an interval, GOLD comes up with a significant modification in its guidelines, which is generally a major overhaul of the pre-existing guidelines. According to the latest 2023 updates, publishe...
Source: Open Respiratory Medicine Journal - April 25, 2024 Category: Respiratory Medicine Authors: Munish Sharma Sushil Joshi Prakash Banjade Shekhar A Ghamande Salim Surani Source Type: research

Prevalence of obstructive sleep apnea in patients with chronic obstructive pulmonary disease in Vietnam
CONCLUSIONS: The prevalence of obstructive sleep apnea in patients with chronic obstructive pulmonary disease in Vietnam was 42.1% for an AHI of ≥ 15 events/h.PMID:38662313 | DOI:10.1007/s11325-024-03035-y (Source: Sleep and Breathing)
Source: Sleep and Breathing - April 25, 2024 Category: Sleep Medicine Authors: Bao Khac Le Minh Hoang Source Type: research

The relationship between prescription rates of oral corticosteroids for respiratory diseases and deprivation in England
This study carried out a multivariable regression analysis of publicly available data and found that deprivation is associated with a statistically significant increase in the proportion of patients receiving an OCS prescription for asthma or COPD at a GP practice level (p < 0.001). The model estimated that the proportion of prescriptions is 1.88% (95% CI 1.83% to 1.92%) and 2.84% (95% CI 2.70% to 2.98%) for the least deprived GP practice and the most deprived GP practice, respectively. This study lays the groundwork for future research using individual patient level data to consider the impact of variation in OCS presc...
Source: Primary Care - April 25, 2024 Category: Primary Care Authors: Erin Barker Jessica Pocock Joe Moss Nick Hex Jordan Rankin Richard Hudson Source Type: research

The relationship between prescription rates of oral corticosteroids for respiratory diseases and deprivation in England
This study carried out a multivariable regression analysis of publicly available data and found that deprivation is associated with a statistically significant increase in the proportion of patients receiving an OCS prescription for asthma or COPD at a GP practice level (p < 0.001). The model estimated that the proportion of prescriptions is 1.88% (95% CI 1.83% to 1.92%) and 2.84% (95% CI 2.70% to 2.98%) for the least deprived GP practice and the most deprived GP practice, respectively. This study lays the groundwork for future research using individual patient level data to consider the impact of variation in OCS presc...
Source: Respiratory Care - April 25, 2024 Category: Respiratory Medicine Authors: Erin Barker Jessica Pocock Joe Moss Nick Hex Jordan Rankin Richard Hudson Source Type: research

Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 Guidelines Reviewed
Open Respir Med J. 2024 Jan 10;18:e18743064279064. doi: 10.2174/0118743064279064231227070344. eCollection 2024.ABSTRACTThe Global Initiative for Chronic Obstructive Lung Disease (GOLD) report is an essential resource for all clinicians who strive to provide optimal care to patients with chronic obstructive lung disease (COPD). The annual report of GOLD makes few revisions and updates besides including data from the preceding year. At an interval, GOLD comes up with a significant modification in its guidelines, which is generally a major overhaul of the pre-existing guidelines. According to the latest 2023 updates, publishe...
Source: Respiratory Care - April 25, 2024 Category: Respiratory Medicine Authors: Munish Sharma Sushil Joshi Prakash Banjade Shekhar A Ghamande Salim Surani Source Type: research

Inappropriate Peak Inspiratory Flow Rate in the Patients with Stable Chronic Obstructive Pulmonary Disease in Korea
CONCLUSIONS: Prevalence of inappropriate PIFR among patients with COPD is 17.2% for aerosol device users and 42.1% for DPI users. Suboptimal PIFR correlates with female gender, shorter stature, lower weight and MVV in DPI users.PMID:38659389 | DOI:10.4046/trd.2023.0195 (Source: Respiratory Care)
Source: Respiratory Care - April 25, 2024 Category: Respiratory Medicine Authors: Seong Hwan Youn Hyun Jung Kim Jae Seok Park Sun Hyo Park Yong Shik Kwon Mi-Ae Kim Source Type: research