Pneumologie.
Authors: PMID: 30999376 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - April 19, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[The Role of Air Pollutants for Health - A Reply to the Expert Opinion of the International Society for Environmental Epidemiology (ISEE) and the European Respiratory Society (ERS)].
Authors: Köhler D, Hetzel M, Klingner M, Koch T, Ewig S, Becher G, Lindemann H, Voshaar T, Costabel U PMID: 30991436 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - April 18, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Breathing: Ambient Air Pollution and Health - Part I].
Authors: Schulz H, Karrasch S, Bölke G, Cyrys J, Hornberg C, Pickford R, Schneider A, Witt C, Hoffmann B PMID: 30991437 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - April 18, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

Spiroergometrie – Schritt für Schritt.
Spiroergometrie – Schritt für Schritt. Pneumologie. 2019 Apr;73(4):233-239 Authors: Semper H, Kühnelt P, Seipp P PMID: 30947357 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - April 5, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Hemoptysis in Pregnancy].
Authors: Forster F, Schulte W Abstract Here we present an extremely rare but important cause of pulmonary hemorrhage during pregnancy. A 41-year-old patient was seen with hemoptysis in the 29th week of her pregnancy which was initially assessed as unspecific inflammation. At the 34th week of pregnancy, she presented again, this time with hemoptoe and dizziness caused by an unknown idiopathic pulmonary AV malformation. The patient underwent extensive interdisciplinary evaluation including bronchoscopy, emergency cesarean section was performed, which was followed by CT scan and VATS/minithoracotomy with segment resec...
Source: Pneumologie - March 23, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Lung Function, Lung Clearance Index und Bronchial Inflammation in Children and Adolescents with Bronchiolitis obliterans].
Authors: Belachew N, Jerkic S, Michel F, Schubert R, Zielen S, Rosewich M Abstract INTRODUCTION:  Bronchiolitis obliterans (BO) is a rare and severe pulmonary disease which can occur due to airway infection or as a result of stem cell or lung transplantation. Our goal was to study the lung function and airway inflammation among BO patients. Furthermore, we examined the potential of the lung clearance index (LCI) for BO diagnostics among that group. METHODS:  16 BO patients (age: 16.7; 9.6 - 25.3 years) and 17 healthy controls (age: 16.6; 7.6 - 25.0 years) participated in the study. Lung functi...
Source: Pneumologie - March 23, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Prescriptions for Asthma and COPD in Germany for the Years 2007, 2010, 2013, 2015  - 2017].
[Prescriptions for Asthma and COPD in Germany for the Years 2007, 2010, 2013, 2015 - 2017]. Pneumologie. 2019 Mar 20;: Authors: Hausen T Abstract Numbers of prescriptions of the most important substances/combinations for the treatment of asthma and COPD have been extracted out of the sum of all prescriptions of a statistically relevant number of family physicians, internal medicine specialists and pneumologists and analysed.Prescriptions of inhalation drugs showed an increase and those of oral drugs a decrease in therapy of asthma and COPD over a period of 10 years.With asthma there was a clear inc...
Source: Pneumologie - March 23, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Monitoring of None-invasive Ventilated Patients in a Home Care Setting].
Authors: Herberger K, Nafe M, Wiesner B, Grohé C Abstract There is a paucity of data about the at home monitoring and the outpatient setting and care of patients with non-invasive ventilation. We here show, in a prospective study, that both standardized outpatient care visits as well as quality of life monitoring at home are safe and feasible. Monitoring and managing the quality of care at home did not lead to an increase of non-elective hospitalisations or deterioration of respiratory disease burden. PMID: 30895591 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - March 23, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Different Prevalences of Pneumological Disease Patterns in Outpatient and Inpatient Care].
CONCLUSION:  Despite many commonalities in the focus of treatment in pneumological inpatient and outpatient care, there are also substantial differences between the two. These affect medical training, the conduct of clinical studies, and in particular, patient care. In order to maintain a high level of medical care in all areas of pneumology a close exchange between inpatient and outpatient sector seems crucial. In the end, the availability of medical expertise across both sectors will benefit all: physicians, patients and medical science. PMID: 30895592 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - March 23, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[The Nocturnal Respiratory Rate in COPD Patients of Varying GOLD Severity with/without Nicotine Consumption: Calculation by Means of Breath Sound Analysis].
Authors: Schudt F, Gross V, Sohrabi K, Fischer P, Hofmann S, Noeh C, Hildebrandt O, Koehler U Abstract Respiratory rate is an important risk marker and enables early detection of critically ill and vulnerable patients in clinical routine. The aim of this pilot study with 31 patients (COPD severity levels II - IV) was to determine the mean nocturnal respiratory rate based on breath sound recordings and to investigate the dependence of respiratory rate on COPD severity level and smoker status. The mean respiratory rate of the total collective was 19/min. For the COPD-GOLD severity levels, no significant differenc...
Source: Pneumologie - March 23, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

Leserbrief.
Authors: Velasco Garrido M PMID: 30861542 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - March 13, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

Antwort.
Authors: Rabe KF PMID: 30861543 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - March 13, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Tremendous Increase of Home Care in Ventilated and Tracheostomized Patients - Reasons, Consequences, Solutions].
Authors: Köhler D PMID: 30861544 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - March 13, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Test Your Knowledge].
Authors: Gülker JE, Keßler M, Freyhardt P PMID: 30861545 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - March 13, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Guidelines of the German Respiratory Society for Diagnosis and Treatment of Adults Suffering from Acute, Subacute and Chronic Cough].
Authors: Kardos P, Dinh QT, Fuchs KH, Gillissen A, Klimek L, Koehler M, Sitter H, Worth H Abstract The present 2019 S2k consensus guideline of the German Respiratory Society was written - in contrast to the predecessor more general S3 guidelines from 2004 and 2010 - for pneumologists, since 2014 the German College of General Practitioners and Family Physicians (DEGAM) published his own cough guidelines.The guideline contains 48 recommendations agreed by consensus and 16 statements, which are explained in the background text in the following nine chapters: epidemiology, physiology, classification, acute, subacute or...
Source: Pneumologie - February 20, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Lobectomy of Right Lower Lobe Eight Years after Foreign Body Aspiration].
Authors: Herrmann D, Volmerig J, Wolf R, Neuhaus G, Schwamborn M, Ewig S, Hecker E Abstract A young man presented with haemoptysis, eight years after foreign body aspiration. The initial evaluation took place in the emergency department of a general hospital. However, neither chest x-ray nor bronchoscopy were performed. Bronchoscopy performed in our hospital revealed a foreign body in right lower lobe bronchus. Extraction failed because it was embedded in granulation tissue. The chronic atelectasis of right lower lobe and recurrent bronchopulmonary infections during the last years were the indication for lobectomy....
Source: Pneumologie - February 16, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Prof. Dr. med. Bernd Sch önhofer: Pioneer of Prolonged Weaning].
[Prof. Dr. med. Bernd Schönhofer: Pioneer of Prolonged Weaning]. Pneumologie. 2019 Feb;73(2):71-73 Authors: Windisch W, Köhler D, Criée CP PMID: 30759493 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - February 15, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[WeanNet: The Network of Respiratory Weaning Centers].
Authors: Schönhofer B Abstract Invasive ventilation via endotracheal tube as access to the airways often is treatment of choice of acute respiratory failure. Multifactor-related increases the number of patients who are dependent on the ventilator for a longer period. The prolonged weaning (or "liberation") from mechanical ventilation therefore has an increasing importance.In Germany since the 90s of the last century, weaning units have been established in lung clinics. With the aim of achieving the highest possible quality of treatment in these weaning centers, the network "WeanNet" was fou...
Source: Pneumologie - February 15, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

Pleurapunktion – Schritt für Schritt.
Pleurapunktion – Schritt für Schritt. Pneumologie. 2019 Feb;73(2):87-93 Authors: Leo F, Makowska M PMID: 30759495 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - February 15, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Primary Immunodeficiency: Primary Antibody Disorders in Respiratory Medicine].
Authors: Evers G, Thrull M, Wittkowski H, Schmidt LH, Mohr M Abstract Clinical manifestations of primary immunodeficiency are heterogeneous, and early diagnosis is challenging. Leading symptoms are recurrent upper and lower respiratory tract infections. Response to antibiotic therapy is often reduced. Beside infectious complications autoimmunity, autoinflammation and malignant diseases occur frequently. About 50 % of all PID patients are diagnosed after childhood, and the main group are patients with primary antibody deficiencies. Treatment of choice is the immunoglobulin substitution and the prophylactic or ther...
Source: Pneumologie - February 15, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Laryngo-Tracheal Resection as an Alternative to Permanent Tracheostomy].
CONCLUSION:  The laryngotracheal resection is a relevant part of cervical tracheal surgery. It can be performed without significantly higher morbidity and can restore lung function and quality of voice. PMID: 30703818 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - February 2, 2019 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Sirolimus for LAM - A New MILEStone Reached?]
Authors: Kreuter M, Wirtz H PMID: 30541159 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - December 14, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Crazy Paving Pattern of the Lung].
Authors: Fisser C, Hamer OW, Eiber R, Pfeifer M, Lerzer C Abstract Pulmonary alveolar proteinosis (PAP) is a rare pulmonary disease. PAP results from impaired surfactant clearance. In adults, autoimmune pulmonary alveolar proteinosis is present in 90 - 95 % of the cases. In 5 - 10 %, other etiologies such as toxins and dust exposure, hematological disorders and infections have to be considered. Men between 30 - 60 years are commonly affected. Typical symptoms are cough, dyspnea and alteration in ventilatory function. CT scan of the lung is characterised by a crazy paving pattern. In serological test...
Source: Pneumologie - December 12, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Plessimeter Percussion].
Authors: Keller EM PMID: 30536248 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - December 12, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[A Pioneer of Anatomy - Dryander of Marburg (1500  -1560) and the Anatomic Illustration of the Lung].
[A Pioneer of Anatomy - Dryander of Marburg (1500 -1560) and the Anatomic Illustration of the Lung]. Pneumologie. 2018 Dec 07;: Authors: Koehler U PMID: 30536249 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - December 12, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Medicine and Economy Today].
Authors: Ewig S PMID: 30536250 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - December 12, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[COPD due to Occupational Noxae].
Authors: Baur X Abstract The chronic obstructive pulmonary disease (COPD) is characterised by mainly non-reversible bronchial obstruction with airflow limitation. Typically, it exhibits a progressive course. It is one of the leading causes of morbidity and mortality worldwide. In addition to dominating causative smoking and environmental exposures (especially biomass smoke from cooking with open fire stoves), about 15 % are due to occupational exposure. Relatively rare cases (ca. 6 %) do not show an external noxious influence. Occupational causes are frequently not recognised because a detailed occupational his...
Source: Pneumologie - December 8, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[The Pathogenesis of Pulmonary Emphysema - Laennec was right!]
Authors: Koehler U, Hildebrandt O, Dittrich M, Koehler N, Weissflog A Abstract Pulmonary emphysema is characterised by irreversible destruction and enlargement of alveolar structure distal to terminal bronchioles. Small conducting airways
Source: Pneumologie - December 8, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Statement of the German Respiratory Society (DGP) and the Association of Pneumological Clinics (VPK) on the Role of Pneumology in Tiered Emergency Care].
Authors: Randerath WJ, Hetzel M, Pfeifer M, Voshaar T, Rabe K PMID: 30500958 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - December 5, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Left-sided Chylothorax and Tumor of the Right Anterior Mediastinum].
Authors: Bougioukas I, Seipelt R, Huwer H Abstract An 82-year-old male patient presented with a left-sided spontaneous chylothorax. A computed tomographic scan of the chest revealed a cystic tumor in the right upper anterior mediastinum and nodules in the left mediastinum that we interpreted as enlarged lymph nodes. On suspicion of lymphoma and for therapy of chylothorax, we performed a left-sided thoracotomy. The putative lymph nodes proved to be chylomas. We interpret the right-sided mediastinal tumor as cystic lymphangioma causing the left-sided chylothorax at the junction of thoracic duct and venous system on t...
Source: Pneumologie - November 21, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Drug Output and Aerosol Characteristics of Different Jet Nebulisers for Adults While Simulating the Nebulisation of Salbutamol].
CONCLUSION:  The results of the in vitro simulation studies can be utilised to select an appropriate nebuliser for the individual patient. In order to enhance therapeutic efficacy and patient compliance, a nebuliser with a high RDDR should be selected. PMID: 30453377 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - November 21, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Guideline for the Diagnosis and Treatment of Asthma - Guideline of the German Respiratory Society and the German Atemwegsliga in Cooperation with the Paediatric Respiratory Society and the Austrian Society of Pneumology].
Authors: Buhl R, Bals R, Baur X, Berdel D, Criée CP, Gappa M, Gillissen A, Greulich T, Haidl P, Hamelmann E, Kardos P, Kenn K, Klimek L, Korn S, Lommatzsch M, Magnussen H, Nicolai T, Nowak D, Pfaar O, Rabe KF, Riedler J, Ritz T, Schultz K, Schuster A, Spindler T, Taube C, Taube K, Vogelmeier C, von Leupoldt A, Wantke F, Weise S, Wildhaber J, Worth H, Zacharasiewicz A PMID: 30406626 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - November 10, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Test Your Knowledge].
Authors: Braegelmann C, Jaschke K, Simon B, Hornung T, Bieber T, Wenzel J PMID: 30408829 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - November 10, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Strategies to Overcome Acquired Resistance to EGFR-TKI Therapy Based on T790M Specific Substances using Osimertinib as an Example].
This article elucidates the developmental state of third generation EGFR-TKIs with its focus on Osimertinib, the first and currently the only compound in this class which is approved in Germany. Additionally, the medical importance of molecular diagnosis using tumor tissue and circulating tumor DNA is discussed. PMID: 30408830 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - November 10, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Are Small Airways the Key to Understanding Pathophysiology and Treatment Efficacy in Chronic Obstructive Pulmonary Diseases?]
Authors: Koehler U, Hildebrandt O, Koehler N, Sohrabi K Abstract This review presents updated information on small airways in the pathogenesis of chronic obstructive respiratory diseases. The lungs have a branching structure, segmentally divided from trachea down to the alveoli (generations 1 - 23). Airways can be divided into a conducting (generations 1 - 16) and a respiratory zone (generations 17 - 23). Conducting zone is mainly for air transportation, respiratory zone for gas exchange. Increasing attention has been directed to the role of small airways in chronic obstructive respiratory diseases. The...
Source: Pneumologie - November 10, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Test Your Knowledge].
Authors: Skowasch D, Klein J, Homsi R, Pizarro C PMID: 30304754 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - October 12, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Exercise Testing in Respiratory Medicine - DGP Recommendations].
Authors: Meyer FJ, Borst MM, Buschmann HC, Claussen M, Dumitrescu D, Ewert R, Friedmann-Bette B, Gläser S, Glöckl R, Haring K, Lehnigk B, Ochmann U, Preisser AM, Sorichter S, Westhoff M, Worth H Abstract This document replaces the DGP recommendations published in 1998 and 2013. Based on recent studies and a consensus conference, the indications, choice and performance of the adequate exercise testing method and its necessary technical and staffing setting are discussed. Detailed recommendations are provided: for blood gas analysis and right heart catheterization during exercise, walk tests, spiroergometry...
Source: Pneumologie - October 12, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Waiting List Management and Organ Allocation for Lung Transplantation 2018].
Authors: Kümmel A, Witt C, Schramm R, Wenker M, Buhl R, Gottlieb J Abstract In 2017 an amendment to the German transplant law concerning organ allocation and waiting list management became effective. This implies important consequences on lung transplant centers. Crucial innovations concern the transplant conference, indications for lung transplantation and waiting list management. Certain medical conditions now imply a restriction of waiting list enrollment for patients and there are new options for size-matching of donor lung and recipient. Moreover, the new amendment describes in detail how the clinical par...
Source: Pneumologie - October 12, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Statement of the Association of Pneumological Clinics, the German Respiratory Society and the German Society of Medical Intensive Care Medicine and Emergency Medicine on the Coding of Invasive and Non-Invasive Ventilation (NIV) in Intensive Care].
Authors: PMID: 30165707 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - September 1, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Migration and Tuberculosis].
Authors: Othmer JT, Schönfeld N, Häcker B, Otto-Knapp R, Bauer TT Abstract The majority of the people suffering from tuberculosis in Germany are migrants. The treatment of this demographic still presents certain challenges. Only up to a quarter to a fifth of tuberculosis cases in migrants is being diagnosed by the screening methods that were implemented by The German Protection against Infection Act (Infektionsschutzgesetz, IfSG). Reactivation of latent tuberculosis is the most common cause for tuberculosis in migrants. Easy access to health care is vital for the testing and treatment of latent tuberculos...
Source: Pneumologie - September 1, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Pneumological Assessment with Regard to Performance Demands - Concept: "Load to Capacity"].
[Pneumological Assessment with Regard to Performance Demands - Concept: "Load to Capacity"]. Pneumologie. 2018 Aug 30;: Authors: Kroidl RF, Fröhlich MJ, Welte T PMID: 30165714 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - September 1, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Inhaled Triple Therapy in Severe Chronic Obstructive Pulmonary Disease (COPD)].
Authors: Gillissen A, Paparoupa M, Frings D, Atique B, Koczulla R Abstract COPD (chronic obstructive pulmonary disease) is characterised by persistent airflow obstruction caused by exposure to irritants including cigarette smoke dust, and fumes. Long-acting beta-agonist (LABA) and long-acting muscarinic antagonist (LAMA) in fixed-dose combination inhalers are the pillars of modern COPD therapy. LABA/inhaled corticosteroids (ICS) inhalers have been proved to be particularly efficient in patients with ≥ 2 exacerbations per year. Until recently, although recommended in guidelines for severe and unstable COPD pati...
Source: Pneumologie - August 30, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

Sputumgewinnung – Schritt für Schritt.
Sputumgewinnung – Schritt für Schritt. Pneumologie. 2018 Aug 27;: Authors: Karg O, Avsar K, Hoffmann H PMID: 30149400 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - August 29, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Asthma Control in Adults and Children Must be Improved!]
Authors: Guenter K, Boeselt T, Kroenig J, Hildebrandt O, Koehler N, Viniol C, Koehler U Abstract Medication management of asthma is based on level of asthma control. GINA defined criteria for asthma control include asking about daytime symptoms, limitation of activity, nocturnal symptoms/awakenings and need for reliever treatment. Effective asthma control is necessary for preventing exacerbations and worsening of lung function. Standardized and validated questionnaires such as asthma control test (ACT) help to assess the level of asthma control. Asthma control is classified as controlled, partially controlled or un...
Source: Pneumologie - August 29, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Pneumological Assessment with Regard to Performance Demands - Concept: "Load to Capacity"].
[Pneumological Assessment with Regard to Performance Demands - Concept: "Load to Capacity"]. Pneumologie. 2018 Aug 22;: Authors: Kroidl RF, Fröhlich MJ, Welte T Abstract Professional opinions on and assessments of physical performance must be oriented to the individual capacity of the person in question. Moreover, this performance has to be correlated with the expected physical load at work, sports activities or operative stress. This "Load to Capacity Concept" is already a part of an integrative medical assessment, based on clinical experience and common sense, rather than on ...
Source: Pneumologie - August 23, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Fundamental Changes in the Treatment of Lung Cancer].
Authors: Reinmuth N, Schumann C Abstract In recent years, the diagnosis and medical treatment of lung cancer patients has been changed profoundly. Still being a deadly disease for most patients, new developments in treatment approaches and therapy selection lead to significantly extended duration of disease control and overall survival. This development is evident not only in medical issues but also comprises various political and organisational aspects. These aspects will be briefly characterised and discussed in the following. PMID: 30114723 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - August 17, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Longterm Homecare Augmentation Program in Alpha-1-Antitrypsin Deficient Patients].
CONCLUSIONS: Home care with i. v. augmentation therapy by medical professionals contributes to optimum care through consistent treatment and close health-status monitoring in our collective. Exacerbation-related hospitalizations were largely avoided. "Alpha-1-Mobile" was well accepted, practical, and safe. PMID: 30089330 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - August 10, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

Umgang mit Notfallrespiratoren – Schritt für Schritt.
Umgang mit Notfallrespiratoren – Schritt für Schritt. Pneumologie. 2018 Aug;72(8):575-583 Authors: Kumle B, Merz S, Hauschel M, Kläger K, Kumle K PMID: 30089331 [PubMed - in process] (Source: Pneumologie)
Source: Pneumologie - August 10, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

[Rebiopsy for Patients with Lung Cancer - Joint Opinion from both the Endoscopic and Thoracic Oncology Sections of the German Society of Pneumology (DGP)].
Authors: Brückl WM, Ficker JH, Tiemann M, Schumann C, Reinmuth N, Heigener D, Schütte W, Eberhardt R, Darwiche K, Wagner M Abstract Performing rebiopsies for primary lung cancer and/or their metastases is becoming more and more prominent in daily practice, as the therapeutical spectrum increases and some newer strategies are dependent on immunohistochemical and/or molecular factors. In general, nearly all recurrent lesions or metastases can be reached. However, frequently invasive procedures are necessary with the need to carefully weigh risks and benefits of rebiopsies for the patient in each case. In th...
Source: Pneumologie - August 3, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research

Video-Assisted Thoracoscopic Surgery of Parapneumonic Empyema - a 10-year Single-Centre Experience.
CONCLUSION:  A standardised approach, including VATS, is associated with a high cure, low revision and moderate conversion rates. In view of a still considerable mortality, a higher index of suspicion and detection of advanced stages, especially in younger patients, is required to improve outcomes. PMID: 30071540 [PubMed - as supplied by publisher] (Source: Pneumologie)
Source: Pneumologie - August 3, 2018 Category: Respiratory Medicine Tags: Pneumologie Source Type: research