The new European Guidelines for Pulmonary Hypertension with Updated Commentary of the PH-DACH Conference - A position paper of the German Society for Pneumology and Respiratory Medicine (DGP)
Pneumologie. 2023 Nov;77(11):852-853. doi: 10.1055/a-2146-7472. Epub 2023 Nov 14.NO ABSTRACTPMID:37963474 | DOI:10.1055/a-2146-7472 (Source: Pneumologie)
Source: Pneumologie - November 14, 2023 Category: Respiratory Medicine Authors: Ekkehard Gr ünig Nicola Benjamin J ürgen Behr Dirk Skowasch Katrin Milger-Kneidinger Michael Halank Wolfgang M Kuebler Gabor Kovacs Mona Lichtblau Stefan Guth Christian Apitz Harald Kaemmerer Khodr Tello Silvia Ulrich unter der Schirmherrschaft der Deut Source Type: research

New definition and classification of pulmonary hypertension
Pneumologie. 2023 Nov;77(11):854-861. doi: 10.1055/a-2145-4648. Epub 2023 Nov 14.ABSTRACTIn the recent ESC/ERS guidelines on the diagnosis and management of pulmonary hypertension (PH) several important changes have been made in respect of the definition and classification of PH.The mPAP cut-off for defining PH was lowered. PH is now defined by an mPAP > 20 mmHg assessed by right heart catheterization. Moreover, the PVR threshold for defining precapillary PH was lowered. Precapillary PH is now defined by a PVR > 2 WU and a pulmonary arterial wedge pressure (PAWP) ≤ 15 mmHg. Furthermore, the increasing evidence for ...
Source: Pneumologie - November 14, 2023 Category: Respiratory Medicine Authors: Philipp Douschan Benjamin Egenlauf Henning Gall Ekkehard Gr ünig Alfred Hager Melanie Heberling Thomas Koehler Horst Olschewski Hans-J ürgen Seyfarth Athiththan Yogeswaran Silvia Ulrich Gabor Kovacs Source Type: research

Genetic diagnostics and molecular approaches in pulmonary arterial hypertension
Pneumologie. 2023 Nov;77(11):862-870. doi: 10.1055/a-2145-4663. Epub 2023 Nov 14.ABSTRACTThe recently published new European guidelines for diagnosis and treatment of pulmonary hypertension now offer the so far most extensive description of genetic testing and counselling for pulmonary arterial hypertension patients. In addition, the importance of a clinical screening of healthy mutation carriers is highlighted as well as the genetic testing of patients with a suspicion of pulmonary veno-occlusive disease. We frame the respective parts of the guidelines on genetic testing and counselling in the context of recent data and p...
Source: Pneumologie - November 14, 2023 Category: Respiratory Medicine Authors: Christina A Eichstaedt Olympia Bikou Natascha Sommer Ralph T Schermuly Soni S Pullamsetti Norbert Weissmann Lars Harbaum Christoph Tabeling Max Wi ßmüller Vasile Foris Wolfgang M Kuebler Katrin Hinderhofer Andrea Olschewski Grazyna Kwapiszewska Source Type: research

Diagnostic Algorithm and Screening of Pulmonary Hypertension
Pneumologie. 2023 Nov;77(11):871-889. doi: 10.1055/a-2145-4678. Epub 2023 Nov 14.ABSTRACTThe new guidelines for the diagnosis and treatment of pulmonary hypertension include a new diagnostic algorithm and provide specific recommendations for the required diagnostic procedures, including screening methods. These recommendations are commented on by national experts under the auspices of the DACH. These comments provide additional decision support and background information, serving as a further guide for the complex diagnosis of pulmonary hypertension.PMID:37963477 | DOI:10.1055/a-2145-4678 (Source: Pneumologie)
Source: Pneumologie - November 14, 2023 Category: Respiratory Medicine Authors: Khodr Tello Manuel J Richter Nils Kremer Henning Gall Benjamin Egenlauf Stephan Sorichter Melanie Heberling Philipp Douschan Alfred Hager Athiththan Yogeswaran J ürgen Behr Panagiota Xanthouli Matthias Held Source Type: research

Targeted therapy for pulmonary arterial hypertension in patients without comorbidities
Pneumologie. 2023 Nov;77(11):890-900. doi: 10.1055/a-2145-4711. Epub 2023 Nov 14.ABSTRACTThe 2022 guidelines on pulmonary hypertension from the European Society of Cardiology (ESC) and the European Respiratory Society (ERS) provide therapeutic strategies that account for the variability in the clinical presentation of newly diagnosed patients. We summarize treatment recommendations for pulmonary arterial hypertension (PAH) in patients without significant comorbidities, particularly for idiopathic, hereditary, drug/toxin-induced, or connective tissue disease-associated PAH. In this group of patients, multidimensional assess...
Source: Pneumologie - November 14, 2023 Category: Respiratory Medicine Authors: Hans Klose Lars Harbaum Manuel J Richter Mona Lichtblau Alberto M Marra Hans-Joachim Kabitz Satenik Harutyunova Katrin Milger-Kneidinger Tobias J Lange Source Type: research