The search for the "node of life": breathing regulation
Pneumologie. 2023 Dec 14. doi: 10.1055/a-2215-2937. Online ahead of print.ABSTRACTThe article provides a historical overview of developments in the understanding of respiratory rhythm and its control mechanisms over the last two centuries. In the 19th century, a structure in the medulla oblongata was first described as the "node of life". In 1743, Taube discovered the carotid body, and in 1927 the Spaniard de Castro described its morphology and innervation. It was only with the work of father and son Heymans that the physiological and pharmacological significance of the carotid and aortic body was recognized. Today we unde...
Source: Pneumologie - December 14, 2023 Category: Respiratory Medicine Authors: Ulrich Koehler Mikail Aykut Degerli Regina Conradt Olaf Hildebrandt Niklas Koehler Wulf Hildebrandt Source Type: research
Reexpansion pulmonary edema after treatment of primary spontaneous pneumothorax
Pneumologie. 2023 Dec 14. doi: 10.1055/a-2216-0404. Online ahead of print.ABSTRACTA 24-year-old male patient, without further symptoms or comorbidities presented to the emergency room with acute dyspnea after heavy lifting two days before. On auscultation an attenuated vesicular breath was noticed on the right lung. In the initial chest radiograph a right-sided primary spontaneous pneumothorax with minor mediastinal shift was diagnosed. After insertion of a 12-French chest tube the patient's clinical condition deteriorated. The following chest radiograph and computed tomography of the thorax showed a reexpansion pulmonary ...
Source: Pneumologie - December 14, 2023 Category: Respiratory Medicine Authors: Fabian Gleibs Felix D öllinger Martin Witzenrath Ralf-Harto Huebner Jacopo Saccomanno Source Type: research
The search for the "node of life": breathing regulation
Pneumologie. 2023 Dec 14. doi: 10.1055/a-2215-2937. Online ahead of print.ABSTRACTThe article provides a historical overview of developments in the understanding of respiratory rhythm and its control mechanisms over the last two centuries. In the 19th century, a structure in the medulla oblongata was first described as the "node of life". In 1743, Taube discovered the carotid body, and in 1927 the Spaniard de Castro described its morphology and innervation. It was only with the work of father and son Heymans that the physiological and pharmacological significance of the carotid and aortic body was recognized. Today we unde...
Source: Pneumologie - December 14, 2023 Category: Respiratory Medicine Authors: Ulrich Koehler Mikail Aykut Degerli Regina Conradt Olaf Hildebrandt Niklas Koehler Wulf Hildebrandt Source Type: research
Reexpansion pulmonary edema after treatment of primary spontaneous pneumothorax
Pneumologie. 2023 Dec 14. doi: 10.1055/a-2216-0404. Online ahead of print.ABSTRACTA 24-year-old male patient, without further symptoms or comorbidities presented to the emergency room with acute dyspnea after heavy lifting two days before. On auscultation an attenuated vesicular breath was noticed on the right lung. In the initial chest radiograph a right-sided primary spontaneous pneumothorax with minor mediastinal shift was diagnosed. After insertion of a 12-French chest tube the patient's clinical condition deteriorated. The following chest radiograph and computed tomography of the thorax showed a reexpansion pulmonary ...
Source: Pneumologie - December 14, 2023 Category: Respiratory Medicine Authors: Fabian Gleibs Felix D öllinger Martin Witzenrath Ralf-Harto Huebner Jacopo Saccomanno Source Type: research
The search for the "node of life": breathing regulation
Pneumologie. 2023 Dec 14. doi: 10.1055/a-2215-2937. Online ahead of print.ABSTRACTThe article provides a historical overview of developments in the understanding of respiratory rhythm and its control mechanisms over the last two centuries. In the 19th century, a structure in the medulla oblongata was first described as the "node of life". In 1743, Taube discovered the carotid body, and in 1927 the Spaniard de Castro described its morphology and innervation. It was only with the work of father and son Heymans that the physiological and pharmacological significance of the carotid and aortic body was recognized. Today we unde...
Source: Pneumologie - December 14, 2023 Category: Respiratory Medicine Authors: Ulrich Koehler Mikail Aykut Degerli Regina Conradt Olaf Hildebrandt Niklas Koehler Wulf Hildebrandt Source Type: research
Early detection of lung cancer - current status and implementation scenarios
Pneumologie. 2023 Dec;77(12):1016-1026. doi: 10.1055/a-1531-0131. Epub 2023 Dec 13.ABSTRACTThe prognosis of conventionally diagnosed lung cancer patients is still rather poor. Two large, randomized trials using screening by low dose CT could demonstrate that early detection in persons with smoking as risk factor can improve this prognosis. Early detection of lung cancer can be achieved by structured screening programs using low dose CT for persons at increased risk, but in addition also by consequent management of incidental pulmonary nodules, which are seen on imaging for other reasons. Integral part of these programs sho...
Source: Pneumologie - December 13, 2023 Category: Respiratory Medicine Authors: Rudolf M Huber Source Type: research
Development and Update of Guideline-based Quality Indicators in Lung Cancer
CONCLUSIONS: The guideline recommendations are implemented by LCC at a high level. The process presented confirms the successful implementation of the so-called quality cycle in oncology. The QIs developed by the German Guideline Program in Oncology (GGPO) are adopted by the certification program. The implementation of the QI is measured in LCC, evaluated by the German Cancer Society (DKG), and reflected back to the GGPO. The "real world" data have led to the deletion of one QI and show a high implementation of most QIs in LCC.PMID:38081218 | DOI:10.1055/a-2204-4879 (Source: Pneumologie)
Source: Pneumologie - December 11, 2023 Category: Respiratory Medicine Authors: Martin Utzig Hans Hoffmann Niels Reinmuth Wolfgang Sch ütte Thomas Langer Jessica Lobitz Johannes R ückher Simone Wesselmann Source Type: research
4D electromagnetic navigation bronchoscopy for the diagnosis of peripheral pulmonary nodules - An overview and preliminary clinical results
CONCLUSION: Our preliminary data suggest that 4D-ENB is a promising new alternative for the diagnosis of PPNs. To further improve diagnostic yield, 4D-END, which lacks real-time visualization, should be embedded in a multimodal diagnostic procedure with rEBUS and/or fluoroscopy.PMID:38081219 | DOI:10.1055/a-2193-0966 (Source: Pneumologie)
Source: Pneumologie - December 11, 2023 Category: Respiratory Medicine Authors: Thomas Bitter Tielko Seeba J örn Schroeder-Richter Michael Fr öhlich Wissam Duaer Wael Abidi Markus Peter Kindermann Source Type: research
Palliative aspects in pulmonary oncology
Pneumologie. 2023 Dec 11. doi: 10.1055/a-2206-5602. Online ahead of print.ABSTRACTPalliative medicine is an essential part in the treatment of patients with advanced or metastatic NSCLC. A structured palliative approach beginning from diagnoses improves quality of life and maybe even prolong survival. Besides symptom control, the disease trajectory and prognosis should regularly be re-evaluated and discussed with the patient and his loved ones.PMID:38081220 | DOI:10.1055/a-2206-5602 (Source: Pneumologie)
Source: Pneumologie - December 11, 2023 Category: Respiratory Medicine Authors: David Heigener Sandra Delis Source Type: research
Development and Update of Guideline-based Quality Indicators in Lung Cancer
CONCLUSIONS: The guideline recommendations are implemented by LCC at a high level. The process presented confirms the successful implementation of the so-called quality cycle in oncology. The QIs developed by the German Guideline Program in Oncology (GGPO) are adopted by the certification program. The implementation of the QI is measured in LCC, evaluated by the German Cancer Society (DKG), and reflected back to the GGPO. The "real world" data have led to the deletion of one QI and show a high implementation of most QIs in LCC.PMID:38081218 | DOI:10.1055/a-2204-4879 (Source: Pneumologie)
Source: Pneumologie - December 11, 2023 Category: Respiratory Medicine Authors: Martin Utzig Hans Hoffmann Niels Reinmuth Wolfgang Sch ütte Thomas Langer Jessica Lobitz Johannes R ückher Simone Wesselmann Source Type: research
4D electromagnetic navigation bronchoscopy for the diagnosis of peripheral pulmonary nodules - An overview and preliminary clinical results
CONCLUSION: Our preliminary data suggest that 4D-ENB is a promising new alternative for the diagnosis of PPNs. To further improve diagnostic yield, 4D-END, which lacks real-time visualization, should be embedded in a multimodal diagnostic procedure with rEBUS and/or fluoroscopy.PMID:38081219 | DOI:10.1055/a-2193-0966 (Source: Pneumologie)
Source: Pneumologie - December 11, 2023 Category: Respiratory Medicine Authors: Thomas Bitter Tielko Seeba J örn Schroeder-Richter Michael Fr öhlich Wissam Duaer Wael Abidi Markus Peter Kindermann Source Type: research
Palliative aspects in pulmonary oncology
Pneumologie. 2023 Dec 11. doi: 10.1055/a-2206-5602. Online ahead of print.ABSTRACTPalliative medicine is an essential part in the treatment of patients with advanced or metastatic NSCLC. A structured palliative approach beginning from diagnoses improves quality of life and maybe even prolong survival. Besides symptom control, the disease trajectory and prognosis should regularly be re-evaluated and discussed with the patient and his loved ones.PMID:38081220 | DOI:10.1055/a-2206-5602 (Source: Pneumologie)
Source: Pneumologie - December 11, 2023 Category: Respiratory Medicine Authors: David Heigener Sandra Delis Source Type: research
The new European Guidelines for Pulmonary Hypertension with Updated Commentary of the PH-DACH Conference - A position paper of the German Society for Pneumology and Respiratory Medicine (DGP)
Pneumologie. 2023 Nov;77(11):852-853. doi: 10.1055/a-2146-7472. Epub 2023 Nov 14.NO ABSTRACTPMID:37963474 | DOI:10.1055/a-2146-7472 (Source: Pneumologie)
Source: Pneumologie - November 14, 2023 Category: Respiratory Medicine Authors: Ekkehard Gr ünig Nicola Benjamin J ürgen Behr Dirk Skowasch Katrin Milger-Kneidinger Michael Halank Wolfgang M Kuebler Gabor Kovacs Mona Lichtblau Stefan Guth Christian Apitz Harald Kaemmerer Khodr Tello Silvia Ulrich unter der Schirmherrschaft der Deut Source Type: research
New definition and classification of pulmonary hypertension
Pneumologie. 2023 Nov;77(11):854-861. doi: 10.1055/a-2145-4648. Epub 2023 Nov 14.ABSTRACTIn the recent ESC/ERS guidelines on the diagnosis and management of pulmonary hypertension (PH) several important changes have been made in respect of the definition and classification of PH.The mPAP cut-off for defining PH was lowered. PH is now defined by an mPAP > 20 mmHg assessed by right heart catheterization. Moreover, the PVR threshold for defining precapillary PH was lowered. Precapillary PH is now defined by a PVR > 2 WU and a pulmonary arterial wedge pressure (PAWP) ≤ 15 mmHg. Furthermore, the increasing evidence for ...
Source: Pneumologie - November 14, 2023 Category: Respiratory Medicine Authors: Philipp Douschan Benjamin Egenlauf Henning Gall Ekkehard Gr ünig Alfred Hager Melanie Heberling Thomas Koehler Horst Olschewski Hans-J ürgen Seyfarth Athiththan Yogeswaran Silvia Ulrich Gabor Kovacs Source Type: research
