Chronic Obstructive Pulmonary Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A Step Forward to Help Patients With COPD to Perform Ambulatory Exercises
Respir Care. 2024 Apr 22;69(5):627-628. doi: 10.4187/respcare.11956.NO ABSTRACTPMID:38649275 | DOI:10.4187/respcare.11956 (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Jean-Luc Diehl Emmanuelle Gu érin Emmanuel Gu érot Source Type: research

In-Person Versus Remote 6-Minute Walk and Incremental Shuttle Walk Distances in Advanced Lung Disease
CONCLUSIONS: Differences in the distance walked may have resulted from different track lengths, widths, and walking surfaces. This should be considered in test interpretation if tests are repeated under different conditions.PMID:38649272 | DOI:10.4187/respcare.11417 (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Lisa M Wickerson Manoela de Paula Ferreira Dmitry Rozenberg Sunita Mathur Lianne G Singer Source Type: research

Acutely shaky hand
Clinical introduction A 57-year-old man presented acutely with involuntary movements of his left hand. He had hypertension, chronic kidney disease and chronic obstructive pulmonary disease. These movements were best described as sudden, recurrent and arrhythmic loss of tone and power of the left wrist and fingers (video 1). They were most prominent when extending the left wrist, but were absent when the arms were at rest and were not elsewhere. There were no additional neurological deficits. Serum urea, ammonia, sodium, potassium, calcium, magnesium, phosphate and glucose levels were normal. His haematological profile, inf...
Source: Emergency Medicine Journal - April 22, 2024 Category: Emergency Medicine Authors: Tan, Y.-J., Teo, C. H., Chan, C. Tags: EMJ Image Challenge Source Type: research

PPAR γ attenuates cellular senescence of alveolar macrophages in asthma-COPD overlap
CONCLUSION: The findings suggest that senescence in macrophages, particularly alveolar macrophages, plays a crucial role in the pathophysiology of ACO. Furthermore, PPARγ may represent a potential therapeutic target for interventions aimed at modulating senescence-associated processes in ACO.Key words ACO, Asthma, COPD, Macrophages, Senescence, PPARγ.PMID:38643159 | PMC:PMC11032609 | DOI:10.1186/s12931-024-02790-6 (Source: Respiratory Care)
Source: Respiratory Care - April 20, 2024 Category: Respiratory Medicine Authors: Rongjun Wan Prakhyath Srikaram Shaobing Xie Qiong Chen Chengping Hu Mei Wan Yuanyuan Li Peisong Gao Source Type: research

Bacterial interactome disturbance in chronic obstructive pulmonary disease clinical stability and exacerbations
CONCLUSIONS: Bacterial interactome disturbance characterized by reduced antagonistic interactions, rather than change in pathogen abundance or diversity, is a reproducible feature of airway dysbiosis in COPD clinical stability and exacerbations, which suggests that we may target interactome rather than pathogen alone for disease treatment.PMID:38643126 | PMC:PMC11032604 | DOI:10.1186/s12931-024-02802-5 (Source: Respiratory Care)
Source: Respiratory Care - April 20, 2024 Category: Respiratory Medicine Authors: Wei Xiao Yi-Long Chen Long-Yi Du Jiqiu Wu Zhang Wang Bing Mao Fu-Qiang Wen Peter Gerard Gibson Vanessa M McDonald Haopeng Yu Juan-Juan Fu Source Type: research

Suboptimal peak inspiratory flow rate: a noticeable risk factor for inhaler concordance in patients with chronic airway diseases
CONCLUSION: Inhaler concordance was low, and suboptimal PIFR was a risk factor for poor concordance among Chinese patients with chronic airway diseases. In addition, current inhalation devices may not be suitable, and PIFR reassessment should be considered for patients with COPD during exacerbation.TRIAL REGISTRATION NUMBER: The study was registered in chictr.org.cn (ChiCTR2100052527) on 31 October 2021.PMID:38642917 | PMC:PMC11033634 | DOI:10.1136/bmjresp-2023-001981 (Source: Respiratory Care)
Source: Respiratory Care - April 20, 2024 Category: Respiratory Medicine Authors: Weiwei Meng Ruoyan Xiong Zhiqi Zhao Huihui Zeng Yan Chen Source Type: research

A feeling of not being alone – Patients' with COPD experiences of a group‐based self‐management education with a digital website: A qualitative study
AbstractAimTo describe patients' with chronic obstructive pulmonary disease (COPD) experiences of group-based self-management education with a digital website.DesignA qualitative approach with a phenomenologicalmethod. Patients participating in an earlier study, with self-experience of COPD as a special competence, were involved as research partners at the design of this study.MethodsEleven individual and two group interviews with five participants in each group were conducted.ResultsGroup-based self-management education with a digital website supports learning. Sharing experiences with others in similar situations creates...
Source: Nursing Open - April 20, 2024 Category: Nursing Authors: Mia Berglund, Susanne Andersson, Anna Kjellsdotter Tags: RESEARCH ARTICLE Source Type: research

PPAR γ attenuates cellular senescence of alveolar macrophages in asthma-COPD overlap
Asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) represents a complex condition characterized by shared clinical and pathophysiological features of asthma and COPD in older individuals. Howeve... (Source: Respiratory Research)
Source: Respiratory Research - April 20, 2024 Category: Respiratory Medicine Authors: Rongjun Wan, Prakhyath Srikaram, Shaobing Xie, Qiong Chen, Chengping Hu, Mei Wan, Yuanyuan Li and Peisong Gao Tags: Research Source Type: research

Bacterial interactome disturbance in chronic obstructive pulmonary disease clinical stability and exacerbations
Our understanding of airway dysbiosis in chronic obstructive pulmonary disease (COPD) remains incomplete, which may be improved by unraveling the complexity in microbial interactome. (Source: Respiratory Research)
Source: Respiratory Research - April 20, 2024 Category: Respiratory Medicine Authors: Wei Xiao, Yi-long Chen, Long-yi Du, Jiqiu Wu, Zhang Wang, Bing Mao, Fu-qiang Wen, Peter Gerard Gibson, Vanessa M. McDonald, Haopeng Yu and Juan-juan Fu Tags: Research Source Type: research

PTP1B Attenuates the Progression of COPD by Suppressing the SHP-2/Src/ERK1/2/NLRP3 Signaling Pathway
CONCLUSION: Our findings suggest that macrophage intracellular tyrosine phosphatase PTP1B plays a critical role in delaying COPD progression by targeting the SHP-2/Src/ERK1/2/NLRP3 signaling pathway, underscoring its potential as a therapeutic target in COPD management.PMID:38639633 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 19, 2024 Category: Complementary Medicine Authors: Hui Wang Hao Zhang Wei Yuan Source Type: research

The Role of SHP2 in Advancing COPD: Insights into Oxidative Stress, Endoplasmic Reticulum Stress, and Pyroptosis
CONCLUSIONS: SHP2 promotes COPD progression by inducing oxidative stress, endoplasmic reticulum stress, and pyroptosis.PMID:38639622 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 19, 2024 Category: Complementary Medicine Authors: Haidong Ding Rina Wu Source Type: research

Mounier-Kuhn Syndrome in poorly controlled asthma
CONCLUSIONS: Despite its rarity, this syndrome significantly impacts patients' quality of life. Diagnosis and management involve comprehensive evaluations including computed tomography, with a multidisciplinary approach including pulmonologists and radiologists. Exploring its clinical features, associations with other respiratory diseases and treatment options is crucial in managing this rare respiratory condition.PMID:38639468 | DOI:10.1080/02770903.2024.2344168 (Source: Journal of Asthma)
Source: Journal of Asthma - April 19, 2024 Category: Respiratory Medicine Authors: Marta Sol ís García Carolina Cisneros Serrano Ana Sof ía Martín Hernández Jose Mar ía Eiros Bachiller Celeste Marcos Source Type: research

Retraction notice to "In vitro anticholinergic drugs affect CD8+ peripheral blood T-cells apoptosis in COPD" [Immunobiology 217/3 (2012) 345-353]
Immunobiology. 2024 Apr 18:152800. doi: 10.1016/j.imbio.2024.152800. Online ahead of print.NO ABSTRACTPMID:38641460 | DOI:10.1016/j.imbio.2024.152800 (Source: Immunobiology)
Source: Immunobiology - April 19, 2024 Category: Allergy & Immunology Authors: Mirella Profita Loredana Riccobono Angela Marina Montalbano Anna Bonanno Maria Ferraro Giusy Daniela Albano Stefania Gerbino Paola Casarosa Michael Paul Pieper Mark Gjomarkaj Source Type: research