Diet, parasites, and other pathogens of Sunda leopard cats ( Prionailurus javanensis Desmarest 1816) in Aborlan, Palawan Island, Philippines
This study is the first investigation of parasites and other pathogens present in Sunda leopard cats (Prionailurus javanensis) in Aborlan, Palawan, Philippines. With the nature of wild carnivore sampling, four (4) wild Sunda leopard cats were captured in Aborlan, Palawan, Philippines for a period of nine (9) months. Of these, three (3) were considered for blood and fecal examination due to the poor condition of one animal. Rapid diagnostic kits were used to detect the presence of selected pathogens in blood samples while fecal samples were examined for parasite fauna and diet contents. Nine (9) parasite species were identi...
Source: Journal of Parasitic Diseases - January 8, 2021 Category: Parasitology Source Type: research

Antibacterial Drugs for Community-Acquired Pneumonia
Date: January 25, 2021 Issue #:  1616Summary:  Treatment of community-acquired pneumonia (CAP) is usually empiric, with selected antibiotic regimens directed against some of the most common causative pathogens. Recommended empiric regimens are listed in Table 2; recommended antibiotic dosages for treatment of CAP are listed in Tables 3 and 4. Joint guidelines for treatment of CAP by the American Thoracic Society and the Infectious Diseases Society of America (ATS/IDSA) were updated in 2019. (Source: The Medical Letter)
Source: The Medical Letter - December 4, 2020 Category: Drugs & Pharmacology Authors: admin Tags: Amoxicillin Amoxicillin/clavulanate Ampicillin/sulbactam Antibacterials Avelox Azithromycin Baxdela Biaxin cefepime Cefotaxime Cefpodoxime ceftaroline Ceftin Ceftriaxone Cefuroxime Chlamydophila pneumoniae Clarithromycin Source Type: research

The role of typical and atypical pathogens in acute exacerbations of chronic obstructive pulmonary disease
ConclusionThe additional use of DFA forLegionella and multiplex PCR in combination with nonspecific microbiological culturing methods greatly improves the ability to identify infectious agents in acute exacerbations of COPD. There should be a high index of suspicion forP.aeruginosa as a causative organism, particularly in subjects receiving continuous oxygen therapy and/or using NIV andL. pneumophila should certainly be taken into consideration in severe COPD exacerbations. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - October 24, 2020 Category: Respiratory Medicine Authors: Sevilay Yildiz, Nevriye Gonullu, Birsen Pinar Yildiz, Didem Gorgun Hattatoglu, Mert Kuskucu, Kenan Midilli, Gokhan Aygun, Pelin Yuksel Mayda, Benan Musellim Tags: ORIGINAL ARTICLE Source Type: research

The RoleofTypical and Atypical Pathogens in Acute Exacerbations of Chronic Obstructive Pulmonary Disease
ConclusionThe additional use of DFA forLegionella and multiplex PCR in combination with non ‐specific microbiological culturing methods greatly improves the ability to identify infectious agents in acute exacerbations of COPD. There should be a high index of suspicion forP.aeruginosa as a causative organism, particularly in subjects receiving continuous oxygen therapy and/or using NIV andL.pneumophilia should certainly be taken into consideration in severe COPD exacerbations. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - October 8, 2020 Category: Respiratory Medicine Authors: Sevilay Yildiz, Nevriye Gonullu, Birsen Pinar Yildiz, Didem Gorgun Hattatoglu, Mert Kuskucu, Kenan Midilli, Gokhan Aygun, Pelin Yuksel Mayda, Benan Musellim Tags: ORIGINAL ARTICLE Source Type: research

First report of Chlamydophila abortus infection in the dromedary camel (Camelus dromedarius) population in eastern Algeria
Publication date: Available online 1 October 2020Source: Comparative Immunology, Microbiology and Infectious DiseasesAuthor(s): Mohammed Hocine Benaissa, Nora Mimoune, Curtis R. Youngs, Rachid Kaidi, Bernard Faye (Source: Comparative Immunology, Microbiology and Infectious Diseases)
Source: Comparative Immunology, Microbiology and Infectious Diseases - October 1, 2020 Category: Infectious Diseases Source Type: research

Diagnostic utility of serology and polymerase chain reaction for detection of Mycoplasma pneumoniae and Chlamydophila pneumoniae in paediatric community-acquired lower respiratory tract infections
Conclusions: Our study confirms that M. pneumoniae and C. pneumoniae play a significant role in community-acquired LRTIs and a combination of serology and nested PCR is useful for its diagnosis. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - August 28, 2020 Category: Microbiology Authors: Sanchit Kumar Bineeta Kashyap Surinder Kumar Seema Kapoor Source Type: research

Where is Chlamydophila pneumoniae pneumonia?
Publication date: Available online 20 July 2020Source: Respiratory InvestigationAuthor(s): Jiro Fujita, Takeshi Kinjo (Source: Respiratory Investigation)
Source: Respiratory Investigation - July 21, 2020 Category: Respiratory Medicine Source Type: research

Comparison of Cell Culture with Three Conventional Polymerase Chain Reactions for Detecting Chlamydophila pneumoniae in Adult's Pharyngotonsillitis.
Abstract Chlamydophila pneumoniae is an intracellular pathogen responsible for respiratory tract infections. The isolation of the microorganism from clinical specimens is essential for a diagnosis. However, the identification of C. pneumoniae by cell cultures is very difficult besides strongly depending on the sample conditions. The study aimed to investigate, in adult patients with pharyngotonsillitis, the frequency of Chlamydophila pneumoniae detection by cell cultures and three conventional PCRs (a conventional PCR targeting the 16S rRNA gene and two nested PCRs, targeting the 16S rRNA gene and the ompA...
Source: Current Microbiology - June 29, 2020 Category: Microbiology Authors: Stivala A, Genovese C, Bonaccorso C, Di Salvatore V, Petronio Petronio G, Garozzo A, Salmeri M Tags: Curr Microbiol Source Type: research

Multicenter Evaluation of the QIAstat-Dx Respiratory Panel for Detection of Viruses and Bacteria in Nasopharyngeal Swab Specimens [Virology]
The QIAstat-Dx Respiratory Panel (QIAstat-Dx RP) is a multiplex in vitro diagnostic test for the qualitative detection of 20 pathogens directly from nasopharyngeal swab (NPS) specimens. The assay is performed using a simple sample-to-answer platform with results available in approximately 69 min. The pathogens identified are adenovirus, coronavirus 229E, coronavirus HKU1, coronavirus NL63, coronavirus OC43, human metapneumovirus A and B, influenza A, influenza A H1, influenza A H3, influenza A H1N1/2009, influenza B, parainfluenza virus 1, parainfluenza virus 2, parainfluenza virus 3, parainfluenza virus 4, rhinovirus/ente...
Source: Journal of Clinical Microbiology - April 22, 2020 Category: Microbiology Authors: Leber, A. L., Lisby, J. G., Hansen, G., Relich, R. F., Schneider, U. V., Granato, P., Young, S., Pareja, J., Hannet, I. Tags: Virology Source Type: research

Human psittacosis in Japan: notification trends and differences in infection source and age distribution by gender, 2007 to 2016.
CONCLUSIONS: We found important differences in the epidemiology of psittacosis by gender, and the recent decrease in notifications correlated with decreasing C. psittaci prevalence in birds. Risk communications for psittacosis should consider the current epidemiology regarding gender, age, and infection source. PMID: 32253059 [PubMed - as supplied by publisher] (Source: Annals of Epidemiology)
Source: Annals of Epidemiology - March 24, 2020 Category: Epidemiology Authors: Kozuki E, Arima Y, Matsui T, Sanada Y, Ando S, Sunagawa T, Oishi K Tags: Ann Epidemiol Source Type: research

Acute haemorrhagic pericarditis: an unusual presentation of Chlamydophila pneumoniae pneumonia infection.
Authors: Oztek Celebi FZ, Fettah A, Yesil S, Yoldas T, Tanir G, Akcaboy M, Senel S Abstract Chlamydophila pneumoniae, a common cause of respiratory tract infections, rarely leads to serious conditions. A 13-year-old boy with serologically confirmed C. pneumoniae infection presented with pneumonia complicated by pericardial and bilateral pleural effusions. He had a large haemorrhagic pericardial effusion from which 1000 ml of fluid was aspirated over 10 days and a right haemorrhagic pleural effusion which required a chest drain and the removal of 700 ml over 5 days. The addition of clarithromycin to cef...
Source: Paediatrics and international child health - February 15, 2020 Category: Pediatrics Tags: Paediatr Int Child Health Source Type: research

Comparative Clinical Evaluation of NeoPlex RB-8 with Seeplex PneumoBacter ACE for Simultaneous Detection of Eight Respiratory Bacterial Pathogens [Bacteriology]
This study compared the clinical concordance of NeoPlex RB-8 with another method, Seeplex PneumoBacter ACE detection assay (Seeplex PB ACE), which simultaneously detects S. pneumoniae, M. pneumoniae, C. pneumoniae, L. pneumophila, H. influenzae, and B. pertussis. We tested 2,137 nasopharyngeal swab and sputum specimens using both assays. For discordant Bordetella parapertussis and M. catarrhalis specimens, we also performed bidirectional sequencing. For S. pneumoniae, M. pneumoniae, C. pneumoniae, L. pneumophila, H. influenzae, and B. pertussis, which are detected by both NeoPlex RB-8 and Seeplex PB ACE, the positive and n...
Source: Journal of Clinical Microbiology - January 27, 2020 Category: Microbiology Authors: Kim, J. W., Hong, S. S., Lee, I. S., Chi, H. Y., Kim, S.-O., Kim, H. N., Hong, S. P. Tags: Bacteriology Source Type: research

Establishment of a Multiplex Real-Time TaqMan-MGB Polymerase Chain Reaction (PCR) Method for the Simultaneous Detection of Three Animal Chlamydia Species.
CONCLUSIONS The novel established method in this study was able to detect 3 types of Chlamydia species simultaneously, and had high sensitivity, strong specificity, and good stability. It provided a rapid, reliable, and convenient method for epidemiological and clinical diagnosis of chlamydiosis in animals. PMID: 31814605 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - December 11, 2019 Category: Research Tags: Med Sci Monit Source Type: research

Leave it to Lefamulin: A Pleuromutilin Treatment Option in Community-Acquired Bacterial Pneumonia
AbstractLefamulin (BC-3781) is the first systemic pleuromutilin antibiotic found to be safe and effective in the treatment of community-acquired bacterial pneumonia (CABP) in humans. This novel antibiotic was developed to combat the increasing incidence of bacterial resistance to current therapies. As the first semisynthetic pleuromutilin for systemic use in humans, lefamulin has demonstrated efficacy against the most common bacteria responsible for CABP, including strains exhibiting resistance to macrolides, fluoroquinolones, tetracyclines, vancomycin, and beta-lactams. In vitro studies have demonstrated efficacy againstS...
Source: Drugs - November 7, 2019 Category: Drugs & Pharmacology Source Type: research