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Infantile osteopetrosis with delayed development, organomegaly and wandering eyes: case report
Paediatr Int Child Health. 2024 Apr 5:1-3. doi: 10.1080/20469047.2024.2335423. Online ahead of print.ABSTRACTOsteopetrosis encompasses rare inherited metabolic bone disorders with defect in the osteoclast activity. Severe forms of presentation such as malignant infantile osteopetrosis are seen in infants and milder forms in older children. The clinical presentation includes failure to thrive, severe pallor, optic atrophy and hepatosplenomegaly. The disorder is characterised by dense bone on radiography, hence the name marble bone disease. A 10-month-old boy who presented with developmental delay, failure to thrive, nystagm...
Source: Paediatrics and international child health - April 5, 2024 Category: Pediatrics Authors: Ashwini Prithvi Dhrithi Kodethoor Sushma K Sanjiv Lewin Source Type: research

Acute demyelinating encephalomyelitis in a child with pulmonary tuberculosis
Paediatr Int Child Health. 2024 Apr 3:1-3. doi: 10.1080/20469047.2024.2335422. Online ahead of print.ABSTRACTTuberculosis is a leading cause of mortality in children worldwide. One of the greatest challenges in its management is the difficulty of diagnosis as the manifestations are non-specific and often mimic other illnesses. Neurological infection occurs in approximately 1% of patients diagnosed with tuberculosis, and usually takes the form of tuberculous meningitis or tuberculoma. An 11-year-old girl who was diagnosed with acute disseminated encephalomyelitis, a rare immunological manifestation of tuberculosis, is prese...
Source: Paediatrics and international child health - April 4, 2024 Category: Pediatrics Authors: Jasmine Singh Pallavi Sharma Shivani Randev Narinder Kaur Pankaj Kumar Vishal Guglani Source Type: research

Effectiveness of phototherapy with and without probiotics for the treatment of indirect hyperbilirubinaemia in preterm neonates: a randomised controlled trial
CONCLUSION: Oral probiotics (Saccharomyces boulardii) have a significant effect on the duration of phototherapy for neonatal hyperbilirubinaemia, and they decrease the chances of nosocomial infection. Exploration of clinical outcomes by investigating faecal flora and undertaking large randomised controlled trials of various probiotics are needed.ABBREVIATIONS: ABE: acute bilirubin encephalopathy; CNS: central nervous system; GA: gestational age; IVIG: intravenous immunoglobulin; KSD: kernicterus; NNU: neonatal unit; RCT: randomised controlled trial; S. boulardii: Saccharomyces boulardii.PMID:38482867 | DOI:10.1080/20469047...
Source: Paediatrics and international child health - March 14, 2024 Category: Pediatrics Authors: Hisham Nassif Meshari Alaifan Shadi Tamur Khalid Khadawardi Ammar A Bahauddin Aijaz Ahmed Sarfraz Ahmad Rajinder Singh Bakr H Alhussaini Amber Hassan Source Type: research

The identification of WHO emergency signs in children by nurses at triage in an emergency department
CONCLUSIONS: Effective screening at triage can enable prompt emergency treatment by nurses and can help focus doctors' attention on children who require it most. There is a need for additional training in the identification of some emergency signs.ABBREVIATIONS: CED: children's emergency department; ETAT: emergency triage assessment and treatment; HCC: Hospital Care for Children; PMGH: Port Moresby General Hospital; PNG: Papua New Guinea; WHO: World Health Organization.PMID:38482930 | DOI:10.1080/20469047.2024.2328903 (Source: Paediatrics and international child health)
Source: Paediatrics and international child health - March 14, 2024 Category: Pediatrics Authors: Rachel Masta Everlyn Kukupe Rupert Marcus Trevor Duke Source Type: research