Gaps in the tuberculosis preventive therapy care cascade in children in contact with TB
Paediatr Int Child Health. 2021 Sep 17:1-10. doi: 10.1080/20469047.2021.1971360. Online ahead of print.ABSTRACTBackground: Young children (
Source: Paediatrics and international child health - September 17, 2021 Category: Pediatrics Authors: E Van Ginderdeuren J Bassett C F Hanrahan L Mutunga A Van Rie Source Type: research

A gastric outlet thickened mucosal fold associated with cytomegalovirus infection in an extremely preterm infant managed by surgical resection
Paediatr Int Child Health. 2021 Sep 14:1-4. doi: 10.1080/20469047.2021.1967626. Online ahead of print.ABSTRACTNon-bilious vomiting in preterm neonates discharged from neonatal intensive care units is a common complaint and is often associated with benign conditions such as gastro-oesophageal reflux. A neonate of 27 weeks gestation who presented later with vomiting owing to gastric outlet obstruction is described. He was discharged at 11 weeks of age and required re-admission 1 week later. He had persistent non-bilious vomiting from 7 weeks of age, failure to thrive and metabolic alkalosis. Clinical examination demonstrated...
Source: Paediatrics and international child health - September 14, 2021 Category: Pediatrics Authors: Susmitha Tangirala Prakash Amboiram Umamaheswari Balakrishnan Sandhya Sundaram Prakash Agarwal Usha Devi Source Type: research

Splenic rupture presenting with marked scrotal ecchymosis in a 2-day-old newborn
Paediatr Int Child Health. 2021 Sep 13:1-3. doi: 10.1080/20469047.2021.1971923. Online ahead of print.ABSTRACTSplenic rupture is a rare and severe condition in neonates. The signs and symptoms are vague and non-specific and are often not recognised before the onset of hypovolaemic shock or death. A 2-day-old infant presented with scrotal ecchymosis, and ultrasonography detected haemorrhage in the scrotal, right inguinal and adrenal regions. Computed tomography demonstrated a peri-splenic haematoma. Haemoglobin (Hb) was 2.79 g/dL and, despite repeated transfusions, the Hb level could not be sustained. Exploratory laparotomy...
Source: Paediatrics and international child health - September 13, 2021 Category: Pediatrics Authors: Gaffari Tunc Cengiz G üney Utku Ayg üneş Source Type: research

Neurodevelopmental outcome in neonates with hypoxic-ischaemic encephalopathy managed with therapeutic hypothermia in a tertiary-level public hospital outside an intensive care unit setting
CONCLUSIONS: The relatively low prevalence of disability (32%) at 18-24 months suggests that use of TH in a Level 2 nursery is feasible and possibly beneficial. More studies are needed to confirm these findings.ABBREVIATIONS: aEEG: amplitude electroencephalogram; CP: cerebral palsy; GMDS: Griffiths mental developmental scales; GQ: general quotient; HIC: high-income countries; HIE: hypoxic-ischaemic encephalopathy; LMIC: low- and middle-income countries; LTFU: loss to follow-up; NICU: neonatal intensive care unit; TH: therapeutic hypothermia; TOBY: total body hypothermia.PMID:34493152 | DOI:10.1080/20469047.2021.1967625 (So...
Source: Paediatrics and international child health - September 8, 2021 Category: Pediatrics Authors: S Mbatha F L Nakwa K Thandrayen S Velaphi Source Type: research

Improving recognition and management of children with complicated severe acute malnutrition at a tertiary referral hospital in Malawi: a quality improvement initiative
CONCLUSION: Significant improvement in key quality measures represents early progress towards the larger goal of improving patient outcomes, most notably mortality, in children admitted with SAM.PMID:34494509 | DOI:10.1080/20469047.2021.1967627 (Source: Paediatrics and international child health)
Source: Paediatrics and international child health - September 8, 2021 Category: Pediatrics Authors: Bryan J Vonasek Susan Mhango Heather L Crouse Temwachi Nyangulu Wilfred Gaven Emily Ciccone Alexander Kondwani Binita Patel Elizabeth Fitzgerald Pediatric Alliance for Child Health Improvement in Malawi at Kamuzu Central Hospital and Environs (PACHIMAKE) Source Type: research

Neurodevelopmental outcome in neonates with hypoxic-ischaemic encephalopathy managed with therapeutic hypothermia in a tertiary-level public hospital outside an intensive care unit setting
CONCLUSIONS: The relatively low prevalence of disability (32%) at 18-24 months suggests that use of TH in a Level 2 nursery is feasible and possibly beneficial. More studies are needed to confirm these findings.ABBREVIATIONS: aEEG: amplitude electroencephalogram; CP: cerebral palsy; GMDS: Griffiths mental developmental scales; GQ: general quotient; HIC: high-income countries; HIE: hypoxic-ischaemic encephalopathy; LMIC: low- and middle-income countries; LTFU: loss to follow-up; NICU: neonatal intensive care unit; TH: therapeutic hypothermia; TOBY: total body hypothermia.PMID:34493152 | DOI:10.1080/20469047.2021.1967625 (So...
Source: Paediatrics and international child health - September 8, 2021 Category: Pediatrics Authors: S Mbatha F L Nakwa K Thandrayen S Velaphi Source Type: research

Improving recognition and management of children with complicated severe acute malnutrition at a tertiary referral hospital in Malawi: a quality improvement initiative
CONCLUSION: Significant improvement in key quality measures represents early progress towards the larger goal of improving patient outcomes, most notably mortality, in children admitted with SAM.PMID:34494509 | DOI:10.1080/20469047.2021.1967627 (Source: Paediatrics and international child health)
Source: Paediatrics and international child health - September 8, 2021 Category: Pediatrics Authors: Bryan J Vonasek Susan Mhango Heather L Crouse Temwachi Nyangulu Wilfred Gaven Emily Ciccone Alexander Kondwani Binita Patel Elizabeth Fitzgerald Pediatric Alliance for Child Health Improvement in Malawi at Kamuzu Central Hospital and Environs (PACHIMAKE) Source Type: research

Neurodevelopmental outcome in neonates with hypoxic-ischaemic encephalopathy managed with therapeutic hypothermia in a tertiary-level public hospital outside an intensive care unit setting
CONCLUSIONS: The relatively low prevalence of disability (32%) at 18-24 months suggests that use of TH in a Level 2 nursery is feasible and possibly beneficial. More studies are needed to confirm these findings.ABBREVIATIONS: aEEG: amplitude electroencephalogram; CP: cerebral palsy; GMDS: Griffiths mental developmental scales; GQ: general quotient; HIC: high-income countries; HIE: hypoxic-ischaemic encephalopathy; LMIC: low- and middle-income countries; LTFU: loss to follow-up; NICU: neonatal intensive care unit; TH: therapeutic hypothermia; TOBY: total body hypothermia.PMID:34493152 | DOI:10.1080/20469047.2021.1967625 (So...
Source: Paediatrics and international child health - September 8, 2021 Category: Pediatrics Authors: S Mbatha F L Nakwa K Thandrayen S Velaphi Source Type: research

Improving recognition and management of children with complicated severe acute malnutrition at a tertiary referral hospital in Malawi: a quality improvement initiative
CONCLUSION: Significant improvement in key quality measures represents early progress towards the larger goal of improving patient outcomes, most notably mortality, in children admitted with SAM.PMID:34494509 | DOI:10.1080/20469047.2021.1967627 (Source: Paediatrics and international child health)
Source: Paediatrics and international child health - September 8, 2021 Category: Pediatrics Authors: Bryan J Vonasek Susan Mhango Heather L Crouse Temwachi Nyangulu Wilfred Gaven Emily Ciccone Alexander Kondwani Binita Patel Elizabeth Fitzgerald Pediatric Alliance for Child Health Improvement in Malawi at Kamuzu Central Hospital and Environs (PACHIMAKE) Source Type: research

Neurodevelopmental outcome in neonates with hypoxic-ischaemic encephalopathy managed with therapeutic hypothermia in a tertiary-level public hospital outside an intensive care unit setting
CONCLUSIONS: The relatively low prevalence of disability (32%) at 18-24 months suggests that use of TH in a Level 2 nursery is feasible and possibly beneficial. More studies are needed to confirm these findings.ABBREVIATIONS: aEEG: amplitude electroencephalogram; CP: cerebral palsy; GMDS: Griffiths mental developmental scales; GQ: general quotient; HIC: high-income countries; HIE: hypoxic-ischaemic encephalopathy; LMIC: low- and middle-income countries; LTFU: loss to follow-up; NICU: neonatal intensive care unit; TH: therapeutic hypothermia; TOBY: total body hypothermia.PMID:34493152 | DOI:10.1080/20469047.2021.1967625 (So...
Source: Paediatrics and international child health - September 8, 2021 Category: Pediatrics Authors: S Mbatha F L Nakwa K Thandrayen S Velaphi Source Type: research

Improving recognition and management of children with complicated severe acute malnutrition at a tertiary referral hospital in Malawi: a quality improvement initiative
CONCLUSION: Significant improvement in key quality measures represents early progress towards the larger goal of improving patient outcomes, most notably mortality, in children admitted with SAM.PMID:34494509 | DOI:10.1080/20469047.2021.1967627 (Source: Paediatrics and international child health)
Source: Paediatrics and international child health - September 8, 2021 Category: Pediatrics Authors: Bryan J Vonasek Susan Mhango Heather L Crouse Temwachi Nyangulu Wilfred Gaven Emily Ciccone Alexander Kondwani Binita Patel Elizabeth Fitzgerald Pediatric Alliance for Child Health Improvement in Malawi at Kamuzu Central Hospital and Environs (PACHIMAKE) Source Type: research

Neurodevelopmental outcome in neonates with hypoxic-ischaemic encephalopathy managed with therapeutic hypothermia in a tertiary-level public hospital outside an intensive care unit setting
CONCLUSIONS: The relatively low prevalence of disability (32%) at 18-24 months suggests that use of TH in a Level 2 nursery is feasible and possibly beneficial. More studies are needed to confirm these findings.ABBREVIATIONS: aEEG: amplitude electroencephalogram; CP: cerebral palsy; GMDS: Griffiths mental developmental scales; GQ: general quotient; HIC: high-income countries; HIE: hypoxic-ischaemic encephalopathy; LMIC: low- and middle-income countries; LTFU: loss to follow-up; NICU: neonatal intensive care unit; TH: therapeutic hypothermia; TOBY: total body hypothermia.PMID:34493152 | DOI:10.1080/20469047.2021.1967625 (So...
Source: Paediatrics and international child health - September 8, 2021 Category: Pediatrics Authors: S Mbatha F L Nakwa K Thandrayen S Velaphi Source Type: research

Improving recognition and management of children with complicated severe acute malnutrition at a tertiary referral hospital in Malawi: a quality improvement initiative
CONCLUSION: Significant improvement in key quality measures represents early progress towards the larger goal of improving patient outcomes, most notably mortality, in children admitted with SAM.PMID:34494509 | DOI:10.1080/20469047.2021.1967627 (Source: Paediatrics and international child health)
Source: Paediatrics and international child health - September 8, 2021 Category: Pediatrics Authors: Bryan J Vonasek Susan Mhango Heather L Crouse Temwachi Nyangulu Wilfred Gaven Emily Ciccone Alexander Kondwani Binita Patel Elizabeth Fitzgerald Pediatric Alliance for Child Health Improvement in Malawi at Kamuzu Central Hospital and Environs (PACHIMAKE) Source Type: research

Aortic thrombosis in a neonate with COVID-19-related fetal inflammatory response syndrome requiring amputation of the leg: a case report
Paediatr Int Child Health. 2021 Sep 7:1-6. doi: 10.1080/20469047.2021.1968596. Online ahead of print.ABSTRACTNeonatal infection with SARS-CoV-2 is considered to have no major complications. A neonate with lower limb gangrene owing to spontaneous aortic thrombosis in the setting of a fetal inflammatory response syndrome (FIRS) post-intrauterine COVID-19 infection is presented. A healthy full-term newborn discharged from hospital on Day 3 developed irritability and progressive blackish discoloration of the toes of the right lower limb on Day 6 of life. Doppler imaging revealed acute thrombosis of the abdominal aorta with a c...
Source: Paediatrics and international child health - September 7, 2021 Category: Pediatrics Authors: Priyanka S Amonkar Jeetendra B Gavhane Suhas N Kharche Sameer S Kadam Dattatray B Bhusare Source Type: research

Protein-losing enteropathy caused by < em > Yersinia enterocolitica < /em > colitis
Paediatr Int Child Health. 2021 Sep 7:1-4. doi: 10.1080/20469047.2021.1890681. Online ahead of print.ABSTRACTA 7-month-old boy was admitted with acute gastro-enteritis accompanied by fever and hyponatraemic dehydration. The clinical course was complicated by severe hypokalaemia and hypo-albuminaemia with anasarca. Protein-losing enteropathy (PLE) owing to Yersinia enterocolitica colitis was diagnosed and was complicated by fungal sepsis owing to Kodomaea ohmeri. Colonoscopy demonstrated multiple diffuse ulcers and sub-epithelial haemorrhages extending from the rectum to the hepatic angle. He required prolonged nutritional ...
Source: Paediatrics and international child health - September 7, 2021 Category: Pediatrics Authors: Lara Ferreira Raquel Amaral Fernanda Gomes Jos é Cabral Source Type: research

Co-existing sickle cell anaemia and inflammatory bowel disease: case report and review of the literature
Paediatr Int Child Health. 2021 Sep 3:1-7. doi: 10.1080/20469047.2021.1936393. Online ahead of print.ABSTRACTSickle cell anaemia (SCA) is a chronic haemolytic anaemia associated with vaso-occlusive painful crises which may affect several systems including the gastro-intestinal system, resulting in abdominal pain. The concurrence of inflammatory bowel disease and haemoglobinopathy is rare. No previously reported concurrent cases of both SCA and ulcerative colitis (UC) in sub-Saharan Africa were found in the literature. A 16-year-old girl with concurrent SCA and UC is presented. She was admitted to University College Hospita...
Source: Paediatrics and international child health - September 3, 2021 Category: Pediatrics Authors: A A Adepoju A Akere G O Ogun B O Ogunbosi A O Asinobi O Bello A E Orimadegun S Allen O O Akinyinka Source Type: research

Efficacy of single phototherapy with low-cost reflective sheets versus single phototherapy alone in mild-to-moderate unconjugated hyperbilirubinaemia in full-term neonates
Paediatr Int Child Health. 2021 Sep 2:1-5. doi: 10.1080/20469047.2021.1958603. Online ahead of print.ABSTRACTBACKGROUND: An economical alternative method of increasing the light intensity of phototherapy for neonatal jaundice is the use of reflective sheets placed on the sides of the incubator.AIM: To determine whether reflective sheets in addition to phototherapy increase the reduction of bilirubin levels and the duration of hospital stay.METHODS: The study was undertaken in the neonatal intensive care unit of Cairo University Children's Hospital. There were two groups: a study group of 90 full-term neonates with neonatal...
Source: Paediatrics and international child health - September 2, 2021 Category: Pediatrics Authors: Amira M Sabry Mortada H F El-Shabrawi Abdelrahman A Abdelrazek Mahmoud F Ali Source Type: research

Sudden-onset haemolacria in an adolescent girl
Paediatr Int Child Health. 2021 Jul 18:1-5. doi: 10.1080/20469047.2021.1949563. Online ahead of print.ABSTRACTHaemolacria, also known as bloody tears, is a physical condition in which a person produces tears partially composed of blood. Multiple disorders can cause haemolacria, including trauma, inflammation, vascular lesions, vicarious menstruation, blood disorders, epistaxis, tumours and psychiatric and systemic disorders. Often, no aetiology is identified. It is usually benign, self-limiting, and the treatment depends on the cause. A 14-year-old girl presented to the paediatric emergency department with sudden onset of ...
Source: Paediatrics and international child health - July 19, 2021 Category: Pediatrics Authors: Ayla Akca Caglar Halise Akca Funda Kurt Leman Akcan Yildiz Pinar Nalcacioglu Onur Buyukkoc Emine Dibek Misirlioglu Source Type: research

Haematohidrosis in a 12-year-old boy: blood, sweat and tears
Paediatr Int Child Health. 2021 Jul 19:1-3. doi: 10.1080/20469047.2021.1951555. Online ahead of print.ABSTRACTA 12-year-old boy presented with a 1-year history of episodes of spontaneous bleeding from multiple sites lasting for a few minutes. His medical history was unremarkable and all the episodes of bleeding began after he was separated from his aunt to whom he was very much attached. She had moved out of their home following her marriage. All haematological investigations were normal. He was diagnosed with haematohidrosis secondary to adjustment disorder, and behavioural therapy was advised and propranolol prescribed. ...
Source: Paediatrics and international child health - July 19, 2021 Category: Pediatrics Authors: Milan Talwar Aakash Chandran Chidambaram Suresh Mekala Narayanan Parameswaran C G Delhikumar Source Type: research

Sudden-onset haemolacria in an adolescent girl
Paediatr Int Child Health. 2021 Jul 18:1-5. doi: 10.1080/20469047.2021.1949563. Online ahead of print.ABSTRACTHaemolacria, also known as bloody tears, is a physical condition in which a person produces tears partially composed of blood. Multiple disorders can cause haemolacria, including trauma, inflammation, vascular lesions, vicarious menstruation, blood disorders, epistaxis, tumours and psychiatric and systemic disorders. Often, no aetiology is identified. It is usually benign, self-limiting, and the treatment depends on the cause. A 14-year-old girl presented to the paediatric emergency department with sudden onset of ...
Source: Paediatrics and international child health - July 19, 2021 Category: Pediatrics Authors: Ayla Akca Caglar Halise Akca Funda Kurt Leman Akcan Yildiz Pinar Nalcacioglu Onur Buyukkoc Emine Dibek Misirlioglu Source Type: research

Haematohidrosis in a 12-year-old boy: blood, sweat and tears
Paediatr Int Child Health. 2021 Jul 19:1-3. doi: 10.1080/20469047.2021.1951555. Online ahead of print.ABSTRACTA 12-year-old boy presented with a 1-year history of episodes of spontaneous bleeding from multiple sites lasting for a few minutes. His medical history was unremarkable and all the episodes of bleeding began after he was separated from his aunt to whom he was very much attached. She had moved out of their home following her marriage. All haematological investigations were normal. He was diagnosed with haematohidrosis secondary to adjustment disorder, and behavioural therapy was advised and propranolol prescribed. ...
Source: Paediatrics and international child health - July 19, 2021 Category: Pediatrics Authors: Milan Talwar Aakash Chandran Chidambaram Suresh Mekala Narayanan Parameswaran C G Delhikumar Source Type: research

Sudden-onset haemolacria in an adolescent girl
Paediatr Int Child Health. 2021 Jul 18:1-5. doi: 10.1080/20469047.2021.1949563. Online ahead of print.ABSTRACTHaemolacria, also known as bloody tears, is a physical condition in which a person produces tears partially composed of blood. Multiple disorders can cause haemolacria, including trauma, inflammation, vascular lesions, vicarious menstruation, blood disorders, epistaxis, tumours and psychiatric and systemic disorders. Often, no aetiology is identified. It is usually benign, self-limiting, and the treatment depends on the cause. A 14-year-old girl presented to the paediatric emergency department with sudden onset of ...
Source: Paediatrics and international child health - July 19, 2021 Category: Pediatrics Authors: Ayla Akca Caglar Halise Akca Funda Kurt Leman Akcan Yildiz Pinar Nalcacioglu Onur Buyukkoc Emine Dibek Misirlioglu Source Type: research

Haematohidrosis in a 12-year-old boy: blood, sweat and tears
Paediatr Int Child Health. 2021 Jul 19:1-3. doi: 10.1080/20469047.2021.1951555. Online ahead of print.ABSTRACTA 12-year-old boy presented with a 1-year history of episodes of spontaneous bleeding from multiple sites lasting for a few minutes. His medical history was unremarkable and all the episodes of bleeding began after he was separated from his aunt to whom he was very much attached. She had moved out of their home following her marriage. All haematological investigations were normal. He was diagnosed with haematohidrosis secondary to adjustment disorder, and behavioural therapy was advised and propranolol prescribed. ...
Source: Paediatrics and international child health - July 19, 2021 Category: Pediatrics Authors: Milan Talwar Aakash Chandran Chidambaram Suresh Mekala Narayanan Parameswaran C G Delhikumar Source Type: research