Can The March of COVID-19 be Halted
Poonam Loomba, Chand Wattal, Anita Chakravarti, Sanghmitra Dutta, Mala Chabbra, Pratibha Kale, Devjani De, Shobha Broor, Ekta GuptaIndian Journal of Medical Microbiology 2020 38(1):128-133 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Poonam Loomba Chand Wattal Anita Chakravarti Sanghmitra Dutta Mala Chabbra Pratibha Kale Devjani De Shobha Broor Ekta Gupta Source Type: research

Two cases of Nocardia bacteraemia in solid organ transplant recipients
We report two cases of Nocardia bacteraemia in solid organ transplant recipients-Nocardia cyriacigeorgica bacteraemia in liver transplant recipient and concomitant Nocardia farcinica bacteraemia and cyclosporiasis in a heart transplant recipient. Prompt recognition of early bacteraemia with initiation of antibiotic therapy may avoid the complications of disseminated disease in the solid organ transplant recipients. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Ranganathan N Iyer Jangam Rekha Rao Shivaprakash M Rudramurthy Dharmesh Kapoor Source Type: research

Safety and efficacy of tocilizumab in the treatment of severe acute respiratory syndrome coronavirus-2 pneumonia: A retrospective cohort study
Conclusions: TCZ is likely a safe and effective modality of treatment for improving clinical and laboratory parameters of SARS CoV-2 patients with a reduction in ICU stay and ventilatory care need. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Atul Patel Kinjal Shah Mitkumar Dharsandiya Ketan Patel Tushar Patel Mukesh Patel Tea Reljic Ambuj Kumar Source Type: research

Candidaemia in a tertiary care centre of developing country: Monitoring possible change in spectrum of agents and antifungal susceptibility
Conclusion: Local epidemiology of candidaemia at our centre was distinct regarding prevalence and change of spectrum of species. The identification of rare species was possible after the introduction of MALDI-TOF. With the emergence of multidrug-resistant C. auris and resistance in other species, routine AFST has become imperative. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Harsimran Kaur Shreya Singh Shivaprakash M Rudramurthy Anup Kumar Ghosh Muralidharan Jayashree Yaddanapudi Narayana Pallab Ray Arunaloke Chakrabarti Source Type: research

Prevalence and antimicrobial profile of Shigella isolates in a tertiary care hospital of North Karnataka: A 12-year study
Conclusions: S. flexneri was the most prevalent species isolated at this centre. Shigella isolates from the study showed alarming resistance to recommended antibiotics. Non-typeable Shigella accounted for 34.4% isolates. Molecular discrimination between Shigella and Escherichia coli is essential. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Pavithra Amrath Jain RD Kulkarni S Dutta Ajanta S Ganavali Anuradha S Kalabhavi Praveen C Shetty C Shubhada Manjunath A Hosamani Suma B Appannanavar Deepa R Hanamaraddi Source Type: research

Association of toll-like receptors 2, 4, 9 and 10 genes polymorphisms and Helicobacter pylori-related gastric diseases in Saudi patients
Conclusion: TLR genes polymorphisms may play a role in H. pylori infection susceptibility and may influence its outcomes; however, the ethnic and other factors may modify this effect. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Emad M Eed Yousry A Hawash Amany S Khalifa Khalaf F Alsharif Saleh A Alghamdi Abdulraheem A Almalki Mazen M Almehmadi Khadiga A Ismail Azza A Taha Taisir Saber Source Type: research

Comparative analysis of clinical characteristics, imaging and laboratory findings of different age groups with COVID-19
Conclusion: The clinical characteristics and imaging/laboratory findings of COVID-19 patients vary in different age groups. Personalised criteria should be formulated according to different age groups in the early screening and diagnosis stage. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Xuemei Liu Jie Lv Lin Gan Ying Zhang Feng Sun Bo Meng Andrew Jheon Fang Yan Bin Li Zhou Xuan Xiumin Ma Muhuyati Wulasihana Source Type: research

Molecular capsular typing and multi locus sequence typing of invasive, non-invasive and commensal Streptococcus pneumoniae isolates from North India
Conclusion: MLST sequence analysis shows that invasive isolates were found to be clustered with non-invasive and commensal isolates. Analysis of MLST suggests the possibility of genetic relatedness and exchange of genetic material between invasive, non-invasive and commensal isolates. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Shefali Jain Bimal Kumar Das Neeraj Mahajan Arti Kapil Rama Chaudhry Seema Sood Sushil Kumar Kabra Sada Nand Dwivedi Source Type: research

Continuous ambulatory peritoneal dialysis peritonitis: Microbiology and outcomes
Conclusions: Direct inoculation of peritoneal fluid into automated blood culture bottles increases the positivity rate and also aids in the early detection of CAPD peritonitis, helping reduce morbidity and mortality of PD patients. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Girisha Pindi Vijendra Kawle Rajeshwar Rao Sunkara Murty Satyanarayana Darbha Sasikala Garikaparthi Source Type: research

Human papillomavirus infection rates before and after the introduction of prophylactic vaccines in Kunming, Yunnan, China
Conclusion: Although the overall HPV infection rate in Kunming did not change significantly after the introduction of HPV vaccines, differences in HPV infection rates and multi-typic HPV infection rates were evident in certain age groups. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Guiqian Z Ziqin D Ya X Qiong W Xin F Limei B Hongyan Z Yi S Source Type: research

Colistin susceptibility testing of gram-negative bacilli: Better performance of vitek2 system than E-test compared to broth microdilution method as the gold standard test
Conclusion: Of 138 isolates, meropenem, colistin and dual resistance were detected in 110 (79.7%), 31 (22.5%) and 21 (15.2%) of isolates, respectively. Using the European Committee on Antimicrobial Susceptibility Testing guidelines (susceptible, ≤2 μg/ml), Vitek2 performed better than E-test (essential agreement, 92.2% vs. 63.7%; categorical agreement, 94.1% vs. 93.1%; very major error [VME], 10% vs. 23.3%). However, Vitek2 overcalled resistance than E-test (major error, 4.2% vs. 0%). Considering Chew et al. proposed breakpoints (susceptible, ≤1 μg/ml), VMEs...
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Surojit Das Subhanita Roy Samadrita Roy Gaurav Goelv Subir Sinha Purva Mathur Kamini Walia Sanjay Bhattacharya Source Type: research

In vitro and in vivo fitness of clinical isolates of carbapenem-resistant and -susceptible Acinetobacter baumannii
Conclusions: To the best of our knowledge, this is the first study of its kind from India showing difference in fitness of clinical isolates of CRAB and CSAB. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Sunil Kumar Lipika Singhal Pallab Ray Vikas Gautam Source Type: research

Hepatitis E outbreak in Jaipur due to Genotype IA
Conclusion: The outbreak was due to HEV genotype 1A. The municipal water supply was contaminated and sanitary conditions and waste disposal were poor in the area. Boiling of drinking water, fixing the water supply pipes and frequent hand washing helped in controlling the outbreak. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Bharti Malhotra Farah Deba Pratibha Sharma Khushbu Trivedi Jitendra Tiwari Aradhana Chouhan Ruchi Singh Deepa Meena HN Verma Source Type: research

Generating mucosal and systemic immune response following vaccination of vibrio cholerae adhesion molecule against shigella flexneri infection
Conclusions: 37.8 kDa subunit pili can act as a homologous vaccine candidate to prevent V. cholerae and S. flexneri infection. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Sumarno Reto Prawiro Sri Poeranto Aisyah Amalia Elsa Larissa Widyani Genitri Indraswari Merika Soraya Septha Rully Dwi Pradipto Adrian Prasetya Guntur Rizal Hidayat Safira Nur Alitha Putri Source Type: research

Prevalence of campylobacter enteritis in children under 5 years hospitalised for diarrhoea in two cities of Northeast India
Conclusion: The present study reveals that Campylobacter infection is endemic in the studied regions of Northeast India and microbiological laboratories of the region should actively pursue the isolation or detection of Campylobacter spp. in cases of diarrhoea in routine stool cultures. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Biswajyoti Borkakoty Aniruddha Jakharia Mandakini Das Sarmah Rahul Hazarika Pranjal Jyoti Baruah Chandra Jyoti Bora T Temsu Munmun Gohain Utpala Devi Dipankar Biswas Source Type: research

Mortality from acinetobacter infections as compared to other infections among critically ill patients in South India: A prospective cohort study
Conclusion: In our cohort of critically ill adults with VAP and CLABSI, AR-HAI was associated with poor ventilator outcomes and a trend towards higher mortality. These findings add to the evidence suggesting that A. baumannii is a dangerous pathogen, perhaps even more so than others. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Ajoy Oommen John Hema Paul Saranya Vijayakumar Shalini Anandan Thomas Sudarsan Ooriyapadickal Cherian Abraham Veeraraghavan Balaji Source Type: research

Optimal size of sample pooling for RNA pool testing: An avant-garde for scaling up severe acute respiratory syndrome coronavirus-2 testing
Conclusions: The pooling of samples is a practical way for scaling up testing and ultimately containing the further spread of the CoV disease 2019 pandemic. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Arvind Khodare Abhishek Padhi Ekta Gupta Reshu Agarwal Shantanu Dubey Shiv Kumar Sarin Source Type: research

The importance of intra- and inter-institutional networks for capacity building in severe acute respiratory syndrome coronavirus 2 reverse transcription polymerase chain reaction services: experience from an oncology centre in eastern India
Deepak Kumar Mishra, Gaurav Goel, Neeraj Arora, Shekhar Krishnan, Sanjay Bhattacharya, Purva Mathur, Kamini Walia, Mammen ChandyIndian Journal of Medical Microbiology 2020 38(1):9-17 High-throughput, accurate, cost-effective and rapid testing for severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) is the need of the hour in face of the global coronavirus disease pandemic. This target is achievable, within a relatively short time through capacity building of reverse transcription polymerase chain reaction (RT-PCR) tests by utilising the strengths of intra and inter institutional networks. These networks act as for...
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Deepak Kumar Mishra Gaurav Goel Neeraj Arora Shekhar Krishnan Sanjay Bhattacharya Purva Mathur Kamini Walia Mammen Chandy Source Type: research

Current understanding, knowledge gaps and a perspective on the future of COVID-19 Infections: A systematic review
Anita Chakravarti, Shalini Upadhyay, Tanisha Bharara, Shobha BroorIndian Journal of Medical Microbiology 2020 38(1):1-8 A novel coronavirus infection, which began as an outbreak of unusual viral pneumonia in Wuhan, a central city in China, has evolved into a global health crisis. The outbreak is an unembellished reminder of the hazard coronaviruses pose to public health. Government and researchers around the world have been taking swift measures to control the outbreak and conduct aetiological studies to understand the various facets of the outbreak. This review is an attempt at providing an insight about the current unde...
Source: Indian Journal of Medical Microbiology - July 25, 2020 Category: Microbiology Authors: Anita Chakravarti Shalini Upadhyay Tanisha Bharara Shobha Broor Source Type: research

Will the recently reinstated clsi 2020 breakpoints of norfloxacin for urinary isolates work for India ? & #8211; Tertiary care experience and evidence
Rani Diana Sahni, Balaji Veeraraghavan, MS Dhiviya Prabaa, Jobin John JacobIndian Journal of Medical Microbiology 2019 37(4):600-601 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Rani Diana Sahni Balaji Veeraraghavan MS Dhiviya Prabaa Jobin John Jacob Source Type: research

Clinico-microbiological profile of invasive pneumococcal disease amongst hospitalised children in South India
Sundaram Balasubramanian, Praachi Singh, K Dhanalakshmi, Sulochana Putlibai, Rosemol VargheseIndian Journal of Medical Microbiology 2019 37(4):598-599 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Sundaram Balasubramanian Praachi Singh K Dhanalakshmi Sulochana Putlibai Rosemol Varghese Source Type: research

Under diagnosis of the lymphogranuloma venereum serovars in the Indian population
Deepak Juyal, Jyoti Rawre, Benu DhawanIndian Journal of Medical Microbiology 2019 37(4):595-597 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Deepak Juyal Jyoti Rawre Benu Dhawan Source Type: research

Emerging atypical non-lactose-fermenting phenotypic variants of klebsiella pneumoniae and escherichia coli in admitted patients of a trauma centre
Vijeta Bajpai, Purva MathurIndian Journal of Medical Microbiology 2019 37(4):593-594 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Vijeta Bajpai Purva Mathur Source Type: research

A rare aetiology of spinal epidural abscess
Lata Sheoran, Neeraj Goel, Shankar Acharya, Nitin Adsul, Chand WattalIndian Journal of Medical Microbiology 2019 37(4):590-592 Spinal epidural abscess (SEA) due to Streptococcus pneumoniae is a rare entity, but it is associated with high mortality. Here, we describe a rare case of pneumococcal SEA in an immunocompetent adult who presented with fever, lower back pain and paresis. Central nervous system examination revealed a decreased power in bilateral lower limbs. Magnetic resonance imaging of the lumbosacral spine showed loculated pus collection in the epidural space at the level of L4–L5 vertebrae. Pus obtained f...
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Lata Sheoran Neeraj Goel Shankar Acharya Nitin Adsul Chand Wattal Source Type: research

A rare association of Mycobacterium tuberculosis infection of kidney and urinary tract with immunoglobulin A nephropathy
Immanuel Pradeep, Sneha Haridas Anupama, Priyanka Koshy, Abraham Kurien, Anusha Rohit, Milly Mathew, Rajeevalochana Parthasarathy, Georgi AbrahamIndian Journal of Medical Microbiology 2019 37(4):587-589 Mycobacterium tuberculosis(MTB)-related secondary immunoglobulin A (IgA) nephropathy is reported in a 72-year-old male patient. The patient was diagnosed to have MTB infection of the kidney and genitourinary tract which was diagnosed by the demonstration of the organism by GeneXpert Ultra and culture. Concurrent kidney biopsy showed IgA nephropathy. The patient responded to urethral double-J stenting and four-drug antitube...
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Immanuel Pradeep Sneha Haridas Anupama Priyanka Koshy Abraham Kurien Anusha Rohit Milly Mathew Rajeevalochana Parthasarathy Georgi Abraham Source Type: research

Assessment of two immunoassays for detection of IgM antibodies to scrub typhus using a serum panel
Divyaa Elangovan, Susmitha Perumalla, Winsley Rose, Valsan Philip Verghese, Joy Mammen, MS Gowri, John Antony Jude PrakashIndian Journal of Medical Microbiology 2019 37(4):584-586Laboratory tests are necessary for diagnosis of scrub typhus (ST) especially in the absence of the distinctive eschar. Performance of an ELISA and ICT (immunochromatography) to detect IgM antibodies to scrub typhus was assessed using a panel of 346 sera chosen from healthy individuals, those with scrub typhus and scrub-typhus like illness. A sensitivity of 98.7% for ST IgM ICT and 97.4% for ST IgM ELISA was observed while specificity was 9...
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Divyaa Elangovan Susmitha Perumalla Winsley Rose Valsan Philip Verghese Joy Mammen MS Gowri John Antony Jude Prakash Source Type: research

Interaction of human immunodeficiency virus-1 and human immunodeficiency virus-2 capsid amino acid variants with human tripartite motif 5 & #945; protein SPRY domain and its association with pathogenesis
Conclusion: Polymorphisms in the capsid protein with both HIV-1- and HIV-2-monoinfected individuals showed the difference in the docking energy from the wild type. This is the first study which documents the difference in the usage of loop between the two HIV types for interaction with huTRIM5α. Variations in the capsid protein result in alteration in the binding to the restriction factor huTRIM5α. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Veena Vadhini Ramalingam Suganya Subramanian G John Fletcher Priscilla Rupali George Varghese Susanne Pulimood Lakshmanan Jeyaseelan Balaji Nandagopal Gopalan Sridharan Rajesh Kannangai Source Type: research

Epidemiology and phylogenetic analysis of human rhinovirus/Enterovirus in Odisha, Eastern India
Conclusion: The genotyping and phylogenetic analysis of the HRVs in the current study shows its circulatory pattern, association with risk factors and evolutionary dynamics. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Swagatika Panda Nirmal Kumar Mohakud Soumya Panda Subrat Kumar Source Type: research

Currently circulating genotypes of hepatitis E virus in India, 2014 & #8211;2018
Conclusion: The HEV genotypes 1a was observed to be the currently circulating strain in the regions studied. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Fernandes M Mevis Sasidharanpillai Sabeena Ramachandran Sanjay Sudandiradas Robin Santhosha Devadiga Varamballi Prasad Dsa Oliver Alyusif Ameen Govindakarnavar Arunkumar Source Type: research

Types of human papillomavirus observed in hospital-based population
Conclusions: The study highlighted the type of HPV infection seen among the hospital-based population. For better screening, HPV tests available in the market should include all the types seen in the population. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Priyanka Wagh Priyanka Kulkarni Shilpa Kerkar Hemant Tongaonkar Kedar Deodhar Bharat Rekhi Vinita Salvi Hemangi Chaudhari Himangi Warke Jayanti Mania-Pramanik Source Type: research

Immune response during influenza virus infection among the population of Assam, Northeast India
Conclusions: The study revealed a differential cytokine profile during influenza virus infection in the population, which may influence disease severity. An extended study on host immune response may provide better insights for the use of cytokine antagonists in therapeutic treatments among severe cases of influenza virus infection. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Mousumi Dutta Prafulla Dutta Subhash Medhi Biswajyoti Borkakoty Dipankar Biswas Source Type: research

Evaluating the PGMY-centre hospitalier universitaire vaudois assay as a cost-effective tool for human papillomavirus genotyping in HIV-infected women
Conclusion: The CHUV assay had an acceptable sensitivity, but it lacked specificity for HPV detection. Despite the lower rates of detection of multiple infections from clinical samples, better results were obtained with the WHO reference samples and the ability of the assay to identify the entire range of genotypes suggests that it can be an efficient tool for genotyping. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Pallavi Ravindra Baliga Raghavendran Anantharam Vinotha Thomas Priscilla Rupali Manu Chopra Susanne Pulimood Jessie Lionel Abraham Peedicayil Rajesh Kannangai Manu Gnanamony Priya Abraham Source Type: research

Epidemiology and Antifungal Susceptibility of Infections Caused by Trichosporon Species: An Emerging Non-Candida and Non-Cryptococcus Yeast Worldwide
Conclusion: T. asahii was the most common isolate. Disseminated trichosporonosis is being increasingly reported worldwide including India and represents a challenge for both diagnosis and species identification. Prognosis is limited, and antifungal regimens containing triazoles appear to be the best therapeutic approach. In addition, accurate identification, removal of central venous lines and voriconazole-based treatment along with control of underlying conditions were associated with favourable outcomes. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Sukhwinder Singh Malini Rajinder Capoor Swati Varshney Dipendra Kumar Gupta Pradeep Kumar Verma V Ramesh Source Type: research

Is it safe to do a single-stage implant exit and primary hip replacement ? clinical and microbiological profiling
Conclusion: This study suggests that implant exit and simultaneous arthroplasty for failed fracture fixation should be done with caution due to the high possibility of infection. It may be prudent to opt for a 2 stage revision. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Rahul George TD Hariharan A Arunshankar Divyaa Elangovan Binesh Lal VJ Chandy AT Oommen Pradeep Mathew Poonnoose Source Type: research

Adaptation of blaNDMthrough IncP plasmid within broad host range
Conclusion: This study was able to underscore the presence of IncP plasmid that was harbouring blaNDMand was maintained within diverse host. The finding also highlights the adaptation of the broad-host-range plasmid that responds in terms of transcriptional expression under antibiotic exposure. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Nargis Alom Choudhury Deepjyoti Paul Bhaskar Jyoti Das Debadatta Dhar(Chanda) Amitabha Bhattacharjee Source Type: research

The incidence, aetiology and antimicrobial susceptibility of central line-associated bloodstream infections in intensive care unit patients at a private tertiary care hospital in Mumbai, India
Conclusions: The CLABSI rates at a well-equipped tertiary care hospital are still significantly higher than the USA benchmarks. Alarming rates of drug resistance in Gram-negative pathogens were seen. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Tanu Singhal Sweta Shah Pooja Thakkar Reshma Naik Source Type: research

Utility of dried blood spots in detecting helicobacter pylori infection
Conclusion: No significant difference was observed in detecting H. pylori when ELISA was conducted using IVB or DBS stored at 4°C and transported even after 48 h. This confirms that DBS collected even in compromised conditions in the field can be used for detecting infection. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Abhinendra Kumar Sharayu Mhatre Rajesh Dikshit Source Type: research

Microbiological profile of infections of the hip joint: An Indian perspective
Conclusion: Staphylococcus sp. was the most common pathogen found in hip infections. However, the high incidence of Gram-negative infection requires that prophylactic antibiotics cover these organisms as well. The high resistance to first-line antibiotics should be taken into consideration while making protocols. The knowledge of the microbial profile is especially important when considering arthroplasty for arthritis secondary to hip infections. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: A Arunshankar VJ Chandy Divyaa Elangovan TD Hariharan John Antony Jude Prakash Rahul George Anil T Oommen Pradeep M Poonnoose Source Type: research

Comparative evaluation of microscan walkaway 96 plus ID/AST system and mikrolatest broth microdilution kit in assessing In vitro colistin susceptibility of carbapenem-resistant clinical gram-negative bacterial isolates: Experience from a tertiary care teaching hospital in Rishikesh, Uttarakhand
Conclusions: Data generated by this study will be of help to the clinicians who are often faced with the dilemma of treating multi drug resistant infections with limited treatment options. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Ravi Indrapal Singh Mohit Bhatia KR Anusha Vanya Singh Balram Ji Omar Pratima Gupta Source Type: research

Effectiveness of hand hygiene promotional program based on the WHO multimodal hand hygiene improvement strategy, in terms of compliance and decontamination efficacy in an indian tertiary level neonatal surgical intensive care unit
Conclusion: To the best of our knowledge, this is the first study about the effect of implementation of the WHO MHHIS from an Indian hospital. HHPP was found to be effective in terms of HH compliance and decontamination efficacy. Its implementation is highly recommended to promote HH in a developing country like India. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Alphonsa Muth Thomas Sukhwinder Kaur Manisha Biswal KL N Rao Shashi Vig Source Type: research

Performance of three commercial assays for colistin susceptibility in clinical isolates and Mcr-1 carrying reference strain
Conclusion: Micronaut-S was found to be an acceptable method for colistin AST. In contrast, E-test was unreliable in terms of EA. Vitek-2 was found to be reliable for colistin AST, although it was more prone to CE near the colistin breakpoints. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Chand Wattal Neeraj Goel Jaswinder Kaur Oberoi Sanghamitra Datta Reena Raveendran Source Type: research

A comparative assessment of clinical, pharmacological and antimicrobial profile of novel anti-methicillin-resistant Staphylococcus aureus agent levonadifloxacin: Therapeutic role in nosocomial and community infections
Yamuna Devi Bakthavatchalam, Shoma Vinay Rao, Barney Isaac, Abi Manesh, Senthur Nambi, Subramanian Swaminathan, Vasanth Nagvekar, Vivek Nangia, Peter Victor John, Balaji VeeraraghavanIndian Journal of Medical Microbiology 2019 37(4):478-487Staphylococcus aureus is of significant clinical concern in both community- and hospital-onset infections. The key to the success of S. aureus as a pathogen is its ability to swiftly develop antimicrobial resistance. Methicillin-resistant S. aureus (MRSA) is not only resistant to nearly all beta-lactams but also demonstrates resistance to several classes of antibiotics. A high prevalence...
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Yamuna Devi Bakthavatchalam Shoma Vinay Rao Barney Isaac Abi Manesh Senthur Nambi Subramanian Swaminathan Vasanth Nagvekar Vivek Nangia Peter Victor John Balaji Veeraraghavan Source Type: research

Novel 2019-coronavirus on new year & #39;s Eve
Parakriti Gupta, Kapil Goyal, Poonam Kanta, Arnab Ghosh, Mini P SinghIndian Journal of Medical Microbiology 2019 37(4):459-477An ongoing apocalyptic outbreak of a new virus causing pneumonia-like clusters in Wuhan city, China, has gleamed the world. The outbreak, confirmed on the New Year's Eve 2020, has known no boundaries since then. The number has surpassed that of Severe Acute Respiratory Syndrome (SARS) and Middle East respiratory syndrome (MERS), and is uninterruptedly escalating. Being an RNA virus, it has a propensity to mutate due to the low proofreading capacity of RNA-dependent RNA polymerase. Step-wise muta...
Source: Indian Journal of Medical Microbiology - May 18, 2020 Category: Microbiology Authors: Parakriti Gupta Kapil Goyal Poonam Kanta Arnab Ghosh Mini P Singh Source Type: research

Erratum: Abstracts - Indian journal of medical microbiology - supplement 1 - 2019 - Volume 37
Indian Journal of Medical Microbiology 2019 37(3):457-458 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - January 29, 2020 Category: Microbiology Source Type: research

Fungal infection in a post-renal transplant patient with Diaporthe
K Vichitra, Lokeshwari Gopal, Balajee Govindarao, V Chandrasekaran, Anupma Jyoti KindoIndian Journal of Medical Microbiology 2019 37(3):454-456 Post-renal transplant fungal infections continue to be a major cause of mortality and morbidity. Universally reported fungi are Candida, especially Candida albicans, Cryptococcus, Aspergillus, Trichophyton rubrum and Pityriasis versicolor. Here, we report a case of infection caused by a rare fungus Diaporthe. It is an endophyte reported as plant pathogens and infrequently in humans and mammals. The patient was a renal transplant recipient on immunosuppressant. He had hypothyroidis...
Source: Indian Journal of Medical Microbiology - January 29, 2020 Category: Microbiology Authors: K Vichitra Lokeshwari Gopal Balajee Govindarao V Chandrasekaran Anupma Jyoti Kindo Source Type: research

Paradoxical upgradation response in non-HIV tuberculosis: Report of two cases
Meghana Nathani Kabra, Thrinadh KunapareddyIndian Journal of Medical Microbiology 2019 37(3):450-453 A paradoxical upgradation response in tuberculosis (TB) is defined as the worsening of a pre-existing tubercular lesion or the appearance of a new lesion in a patient whose clinical symptoms initially improved with anti-TB treatment. A paradoxical response is common in HIV patients in the form of immune reconstitution inflammatory syndrome. A similar kind of response can also be seen in immunocompetent patients. Here, we present two cases of non-HIV TB who initially improved with antitubercular therapy (ATT) but worsened t...
Source: Indian Journal of Medical Microbiology - January 29, 2020 Category: Microbiology Authors: Meghana Nathani Kabra Thrinadh Kunapareddy Source Type: research

Utility of Xpert & #174; MTB/RIF in the diagnosis of extrapulmonary tuberculosis
Vidya Krishna, Ram Gopalakrishnan, Anil Tarigopula, Senthur Nambi Panchatcharam, Suresh Kumar Dorairajan, Ramasubramanian VenkatasubramanianIndian Journal of Medical Microbiology 2019 37(3):448-449 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - January 29, 2020 Category: Microbiology Authors: Vidya Krishna Ram Gopalakrishnan Anil Tarigopula Senthur Nambi Panchatcharam Suresh Kumar Dorairajan Ramasubramanian Venkatasubramanian Source Type: research

Group B Streptococcus vaginal colonisation in pregnant women at a tertiary care hospital in Mumbai
Shalmali Deshpande, Tanu Singhal, Suchitra N Pandit, Sweta ShahIndian Journal of Medical Microbiology 2019 37(3):446-447 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - January 29, 2020 Category: Microbiology Authors: Shalmali Deshpande Tanu Singhal Suchitra N Pandit Sweta Shah Source Type: research

Determination of Biofilm-Forming Capacity of Otopathogens Isolated from Discharging Ears in Children with Chronic Otitis Media
This study describes the microorganisms isolated from the middle ear and nasopharynx of children with chronically discharging ears. Middle ear and nasopharyngeal swabs from 89 children were studied, and the microorganisms isolated were assessed for biofilm-forming ability. Methicillin-susceptible Staphylococcus aureus was common in the nasopharynx, while the middle ear showed predominantly pseudomonas and Methicillin-resistant S. aureus. Pseudomonas aeruginosa showed strong biofilm formation, whereas Escherichia coli, Proteus sp. and Providentia sp. were weak biofilm producers. S. aureus isolates were negative for biofilm ...
Source: Indian Journal of Medical Microbiology - January 29, 2020 Category: Microbiology Authors: Zoremsangi Ralte P Naina Anushree Amladi Mary John Shalini Anndan Ajoy Mathew Varghese Source Type: research

Phylogenetic diversity of Orientia tsutsugamushi isolates in patients with scrub typhus in Bengaluru, India
Sneha K Chunchanur, Shwetha J Venugopal, R Ambica, B DakshayaniIndian Journal of Medical Microbiology 2019 37(3):438-441 Scrub typhus has re-emerged as an important cause of acute febrile illness in India. There is a dearth of information on strain diversity of Orientia tsutsugamushi from Karnataka, India, hence the present study sought to address this issue. One hundred clinically suspected cases of scrub typhus/rickettsiosis (as per the DHR-ICMR guidelines) were included. Nested-polymerase chain reaction (PCR) for 56-kDa gene and phylogenetic analysis was performed. PCR was positive in 22 cases and phylogenetic analysis...
Source: Indian Journal of Medical Microbiology - January 29, 2020 Category: Microbiology Authors: Sneha K Chunchanur Shwetha J Venugopal R Ambica B Dakshayani Source Type: research