Infectious pathogens potentially transmitted by semen of the black variety of the Manchega sheep breed: Health constraints for conservation purposes.
Abstract
Conservation of genetic resources from endangered breeds may be conducted through germinal banks. Preservation of healthy samples is paramount to avoid preserving pathogens shed with germinal products. The black variety of Manchega sheep (BMS), and endangered breed endemic to south-central Spain, is the subject of a conservation program; a germinal bank has been recently established. However, several pathogens circulating in BMS flocks may be shed with semen and threaten BMS preservation. Therefore, we investigated the sanitary status of BMS flocks and semen samples from 4 of the 17 flocks in whic...
Source: Animal Reproduction Science - July 16, 2014 Category: Zoology Authors: Ruiz-Fons F, González-Barrio D, Aguilar-Ríos F, Soler AJ, Garde JJ, Gortázar C, Fernández-Santos MD Tags: Anim Reprod Sci Source Type: research
A study on the association between infectious burden and Alzheimer's disease
ConclusionsIB consisting of CMV, HSV‐1, B. burgdorferi, C. pneumoniae and H. pylori is associated with AD. This study supports the role of infection/inflammation in the etiopathogenesis of AD. (Source: European Journal of Neurology)
Source: European Journal of Neurology - June 9, 2014 Category: Neurology Authors: X.‐L. Bu, X.‐Q. Yao, S.‐S. Jiao, F. Zeng, Y.‐H. Liu, Y. Xiang, C.‐R. Liang, Q.‐H. Wang, X. Wang, H.‐Y. Cao, X. Yi, B. Deng, C.‐H. Liu, J. Xu, L.‐L. Zhang, C.‐Y. Gao, Z.‐Q. Xu, M. Zhang, L. Wang, X.‐L. Tan, X. Xu, H.‐D. Zhou, Y. Tags: Original Article Source Type: research
Epidemiology and microbiological investigations of community-acquired pneumonia in children admitted at the emergency department of a university hospital
Highlights: Abstract: Background: The management of children with community-acquired pneumonia (CAP) is largely influenced by the development of new molecular diagnostic tests that allow the simultaneous detection of a wide range of pathogens.Objectives: Evaluation of a diagnostic approach including multiplex PCR assays for revisiting the epidemiology and etiology of CAP in children at hospital.Study design: Children of all ages consulting at the Emergency Department of the University hospital of Saint-Etienne, France, during the 2012–2013 winter period were included. In addition to bacterial cultures, the following path...
Source: Journal of Clinical Virology - May 23, 2014 Category: Virology Authors: Aymeric Cantais, Olivier Mory, Sylvie Pillet, Paul O. Verhoeven, Julie Bonneau, Hugues Patural, Bruno Pozzetto Tags: Full length articles Source Type: research
Atherosclerosis and Alzheimer - diseases with a common cause? Inflammation, oxysterols, vasculature
We present evidence that chronic macrophage CH25H upregulation leads to catalyzed esterification of sterols via 25OHC-driven allosteric activation of ACAT (acyl-CoA cholesterol acyltransferase/SOAT), intracellular accumulation of cholesteryl esters and lipid droplets, vascular occlusion, and overt disease.SummaryWe postulate that AD and ATH are both caused by chronic immunologic challenge that induces CH25H expression and protection against particular infectious agents, but at the expense of longer-term pathology. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - March 21, 2014 Category: Epidemiology Authors: Richard LatheAlexandra SapronovaYuri Kotelevtsev Source Type: research
Association between Chlamydophila pneumoniae infection and risk of coronary heart disease for Japanese: The JPHC study
Conclusion: C. pneumoniae infection was found to be positively associated with risk of coronary heart disease.Highlights: (Source: Atherosclerosis)
Source: Atherosclerosis - March 20, 2014 Category: Cardiology Authors: Naomi Sakurai-Komada, Hiroyasu Iso, Kazuko A. Koike, Ai Ikeda, Mitsumasa Umesawa, Satoyo Ikehara, Manami Inoue, Shoichiro Tsugane Tags: Clinical & Population Research - Epidemiology, Biomarkers, Nutrition Source Type: research
Erythema nodosum in children: evaluation of 39 patients.
Abstract
Erythema nodosum (EN) has been associated with various infectious and noninfectious diseases. A total of 39 EN patients seen between May 2005 and February 2012 were evaluated retrospectively in this study. The etiology of EN was established in 22 of the 39 children (56.4%). Streptococcal infection was the most common cause (23%), followed by tularemia (10.2%) and tuberculosis (latent tuberculosis infection (LTBI) 5%, pulmonary tuberculosis 2.5%). Miscellaneous conditions were as follows: Behçet disease (2.5%), cytomegalovirus (CMV) (2.5%), Giardia lamblia infection (2.5%), and sarcoidosis (2.5%)....
Source: The Turkish Journal of Pediatrics - March 1, 2014 Category: Pediatrics Authors: Aydın-Teke T, Tanır G, Bayhan GI, Metin O, Oz N Tags: Turk J Pediatr Source Type: research
Development of loop-mediated isothermal amplification assay for specific and rapid detection of differential goat Pox virus and Sheep Pox virus
Conclusions:
In summary, the three sets of LAMP primers when combined provide an analytically robust method able to fully distinguish between GTPV and SPPV. The presented LAMP method provides a specific, sensitive and rapid diagnostic tool for the distinction of GTPV and SPPV infections, with the potential to be standardized as a detection method for Capripox viruses in endemic areas. (Source: Epidemiologic Perspectives and Innovations)
Source: Epidemiologic Perspectives and Innovations - January 17, 2014 Category: Epidemiology Authors: Zhixun ZhaoBin FanGuohua WuXinmin YanYingguo LiXiaoli ZhouHua YueXueling DaiHaixia ZhuBo TianJian LiQiang Zhang Source Type: research
A prospective study: inflammation, infection and comorbidity in patients on long‐term dialysis
ConclusionAge, CVD and CVA are predictors for mortality in patients on HD patients, but the presence of C. pneumoniae IgG and inflammation are not. (Source: Journal of Renal Care)
Source: Journal of Renal Care - December 1, 2013 Category: Urology & Nephrology Authors: Türkay Akbaş, Lütfiye Mülazımoğlu, Burak Aksu, Emel Akoğlu Tags: Original research Source Type: research
NOD1 Ligation Suppressed Murine Allergen-Specific T Cell Proliferation and Airway Hyperresponsiveness.
Abstract
The cytosolic Nucleotide Oligomerization Domain (NOD)-like receptors NOD-1 and NOD-2 are important contributors to the intracellular recognition of pathogens including Chlamydophila pneumoniae, but little is known about their influence on allergen-induced airway inflammation. In BALB/c mice, we observed that infection with C. pneumoniae prior to systemic sensitization with ovalbumin (OVA) and local OVA airway exposure diminished airway hyperresponsiveness. Thus, the impact of NOD1 agonist FK156 and NOD2 agonist muramyl dipeptide (MDP) given 6 hours prior to each sensitization or airway challenge w...
Source: Am J Respir Cell Mol... - November 26, 2013 Category: Respiratory Medicine Authors: Tabeling C, Scheer H, Schönrock SM, Runge F, Gutbier B, Lienau J, Hamelmann E, Opitz B, Suttorp N, Mayer K, Behrens GM, Tschernig T, Witzenrath M Tags: Am J Respir Cell Mol Biol Source Type: research
Serosurvey on Schmallenberg Virus and Selected Ovine Reproductive Pathogens in Culled Ewes From Southern Spain
Summary
After the first case of Schmallenberg virus (SBV) was reported in southern Spain (March 2012), a retrospective serological study was carried out in extensive sheep flocks from nearby areas to assess the history of exposure to SBV and other selected ovine reproductive pathogens (Chlamydophila abortus, Coxiella burnetii, Border Disease virus ‘BDV’, Toxoplasma gondii and Neospora caninum). Secondly, the presence of antibodies was investigated in meat juice samples against selected pathogens to validate their use in serosurveys in sheep. A total of 209 Merina and cross‐bred culled ewes belonging to 12 outdoor flo...
Source: Transboundary and Emerging Diseases - November 13, 2013 Category: Veterinary Research Authors: R. J. Astorga, L. Reguillo, M. Hernández, F. Cardoso‐Toset, C. Tarradas, A. Maldonado, J. Gómez‐Laguna Tags: Rapid Communication Source Type: research
Detection of Chlamydophila pneumoniae and human herpesvirus 8 in primary cutaneous anaplastic large-cell lymphoma: a case report
Conclusions:
These findings suggest for the first time a possible association of C. pneumoniae and/or HHV8 infection, or both together, with primary cutaneous anaplastic large-cell lymphoma in non-immunocompromised and HIV-negative subjects. This potential pathogenic association, if confirmed, could provide potential indications for future therapy. (Source: Infectious Agents and Cancer)
Source: Infectious Agents and Cancer - October 7, 2013 Category: Cancer & Oncology Authors: Alessandro BorghiElisabetta CaselliDario Di LucaAdolfo SebastianiPaolo PerriSilva SeraceniCarlo ContiniAnnarosa Virgili Source Type: research
Prospective evaluation for respiratory pathogens in children with sickle cell disease and acute respiratory illness
ConclusionHRV was the most common virus detected in children with sickle cell disease and acute respiratory illness, and was not associated with increased morbidity. Larger prospective studies with asymptomatic controls are needed to study the association of these emerging respiratory viruses with ACS in children with sickle cell disease. Pediatr Blood Cancer © 2013 Wiley Periodicals, Inc. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - October 4, 2013 Category: Cancer & Oncology Authors: Ashok Srinivasan, Winfred C. Wang, Aditya Gaur, Teresa Smith, Zhengming Gu, Guolian Kang, Wing Leung, Randall T. Hayden Tags: Research Article Source Type: research
Intranasal MLV feline herpesvirus and calicivirus effects on bordetellosis
Upper respiratory infections are a common disease syndrome affecting cats in shelters, boarding facilities, and multiple cat households. The primary causes of rhinitis in cats include feline herpesvirus 1 (FHV-1), feline calicivirus (FCV), Bordetella bronchiseptica, Chlamydophila felis, Mycoplasma spp., and some strains of Pasteurella spp. Vaccines are available only for FHV-1, FCV, B. bronchiseptica, and C. felis. No single product of combined vaccines is available that induces protection against all 4 agents. In addition, different strains of each agent can respond differently to vaccination, and no product confers compl...
Source: Advances in Small Animal Medicine and Surgery - October 1, 2013 Category: Veterinary Research Tags: Clinical Pathology Source Type: research
Correlation of Bacterial Coinfection Versus Matrix Metalloproteinase 9 and Tissue Inhibitor of Metalloproteinase 1 Expression in Aortic Aneurysm and Atherosclerosis
Conclusions: The present work favors a role for coinfection of both M pneumoniae and C pneumoniae in the development of aortic atherosclerotic aneurysm, with increased adventitial inflammation, inhibition of TIMP-1 activity, and increased collagen degradation. (Source: Annals of Vascular Surgery)
Source: Annals of Vascular Surgery - September 17, 2013 Category: Surgery Authors: Alessandra Roggério, Nádia Vieira Sambiase, Suely A.P. Palomino, Maria Alice Pedreira de Castro, Erasmo Simão da Silva, Noedir G. Stolf, Maria de Lourdes Higuchi Tags: Basic Science Source Type: research
Potential role of microorganisms in the pathogenesis of rosacea
Rosacea is a skin condition of abnormal inflammation and vascular dysfunction. The active contribution of a microbial agent in the development or progression of rosacea continues to be debated. Research supports the presence of commensal Demodex folliculorum mites at increased density in the skin and associates Helicobacter pylori infection of the gut with rosacea. Fewer studies implicate Staphylococcus epidermidis, Chlamydophila pneumoniae, and the Demodex-associated bacteria Bacillus oleronius. No research, however, provides a mechanism by which colonization by a microorganism translates to manifestation of the condition...
Source: Journal of the American Academy of Dermatology - September 9, 2013 Category: Dermatology Authors: Anna D. Holmes Tags: Reviews Source Type: research
