Community-Acquired Pneumonia in the Asia-Pacific Region
Semin Respir Crit Care Med 2016; 37: 839-854 DOI: 10.1055/s-0036-1592075Community-acquired pneumonia (CAP) is an important cause of mortality and morbidity worldwide. Aging population, dense urbanization, and poor access to health care make the Asia-Pacific region vulnerable to CAP. The high incidence of CAP poses a significant health and economic burden in this region. Common etiologic agents in other global regions including Streptococcus pneumoniae, Mycoplasma pneumoniae, Haemophilus influenzae, Chlamydophila pneumoniae, Staphylococcus aureus, and respiratory viruses are also the most prevalent pathogens in the Asia-Pac...
Source: Seminars in Respiratory and Critical Care Medicine - December 12, 2016 Category: Respiratory Medicine Authors: Song, Jae-Hoon Huh, Kyungmin Chung, Doo Ryeon Tags: Review Article Source Type: research
Insights into structure and function of 30S Ribosomal Protein S2 (30S2) in Chlamydophila pneumoniae: A potent target of pneumonia.
In this study, the protein 30S2 structure was modelled and validated by Ramachandran plot. It is found that the modelled protein under most favoured "core" region was 88.7% and overall G-factor statistics with average score was -0.20. However, seven sequential motifs have been identified for 30S2 with reference codes (PR0095, PF0038, TIGR01012, PTHR11489, SSF52313 and PTHR11489). In addition, seven structural highly conserved residues have been identified in the large cleft are Lys160, Gly161and Arg162 with volume 1288.83Å(3) and average depth of the cleft was 10.75Å. Moreover, biological functions, biochemical process a...
Source: Computational Biology and Chemistry - November 8, 2016 Category: Bioinformatics Authors: Koteswara Reddy G, Nagamalleswara Rao K, Yarrakula K Tags: Comput Biol Chem Source Type: research
Duration of inhaled corticosteroid therapy in children with asthma and frequency of community-acquired pneumonia in them
Conclusions: 1. One-third of asthmatic children had CAP with development of complications (PH, PF, EB).2. Strong positive correlation between frequency of CAP in children and duration of ICS treatment in them for more than 2 years was revealed.3. It is necessary to continue study of relationship between CAP in children receiving long-term ICS therapy and the duration of treatment for prevention of possible complications of hormone therapy. (Source: European Respiratory Journal)
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Nesterenko, Z. Tags: 7.2 Paediatric Asthma and Allergy Source Type: research
Relapses of primary cutaneous anaplastic large-cell lymphoma in a female immunocompetent patient with persistent chlamydophila pneumoniae and human herpesvirus 8 infection
We have previously reported the case of an immunocompetent female patient with a primary cutaneous CD30+ anaplastic large-cell lymphoma (PCALCL) located on her upper right eyelid characterized by the presence ... (Source: Infectious Agents and Cancer)
Source: Infectious Agents and Cancer - July 5, 2016 Category: Cancer & Oncology Authors: Elisabetta Caselli, Alessandro Borghi, Martina Maritati, Roberta Gafà, Giovanni Lanza, Dario Di Luca, Annarosa Virgili and Carlo Contini Source Type: research
Chronic Infection and Severe Asthma
Chronic bacterial infection is implicated in both the development and severity of asthma. The atypical bacteria Mycoplasma pneumoniae and Chlamydophila pneumoniae have been identified in the airways of asthmatics and correlated with clinical features such as adult onset, exacerbation risks, steroid sensitivity, and symptom control. Asthmatic patients with evidence of bacterial infection may benefit from antibiotic treatment directed towards these atypical organisms. Examination of the airway microbiome may identify microbial communities that confer risk for or protection from severe asthma. (Source: Immunology and Allergy ...
Source: Immunology and Allergy Clinics of North America - June 1, 2016 Category: Allergy & Immunology Authors: Tara F. Carr, Monica Kraft Source Type: research
Prognostic value of TH1/TH2 cytokines in infants with wheezing in a three year follow-up study.
CONCLUSION: We have identified TNF-a, as a biomarker, which can be detected in children under 3 years of age and may be useful in the prediction of development of persistence of wheezing later. To further evaluate the usefulness of this and other markers and establish cutoff levels for prediction and use in clinical practice, a larger prospective follow-up study is needed.
PMID: 27238176 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Chkhaidze I, Zirakishvili D, Shavshvishvili N, Barnabishvili N Tags: Pneumonol Alergol Pol Source Type: research
The spectrum of MALT lymphoma at different sites: biological and therapeutic relevance
Extranodal marginal zone (MZ) B-cell lymphomas of the mucosa-associated lymphoid tissue (MALT) arise from lymphoid populations that are induced by chronic inflammation in extranodal sites. The best evidence of an etiopathogenetic link is provided by the association between Helicobacter pylori–positive gastritis and gastric MALT lymphoma. Indeed, successful eradication of this microorganism with antibiotics can be followed by gastric MALT lymphoma regression in most cases. Other microbial agents have been implicated in the pathogenesis of MZ lymphoma arising at different sites. Apart from gastric MALT lymphoma, antibi...
Source: Blood - April 27, 2016 Category: Hematology Authors: Zucca, E., Bertoni, F. Tags: Free Research Articles, Lymphoid Neoplasia, Review Articles, Review Series, Clinical Trials and Observations Source Type: research
Seroprevalence of infectious diseases in saiga antelope (Saiga tatarica tatarica) in Kazakhstan 2012-2014
Publication date: Available online 30 March 2016 Source:Preventive Veterinary Medicine Author(s): Orynbayev B. Mukhit, Beauvais Wendy, Sansyzbay R. Abylay, Rystaeva A. Rashida, Sultankulova T. Kulyaisan, Kerimbaev A. Aslan, Kospanova N. Madina, Kock A. Richard 286 serum samples were collected from three sub-populations of saiga in Kazakhstan (Betpakdala, Ustyurt and Volga-Ural) between 2012 and 2014, and were tested for the presence of antibodies to Brucella spp., bluetongue virus, peste des petits ruminants (PPR) virus, Akabane virus, Schmallenberg virus, Chlamydophila, Toxoplasma, Mycobacterium avium ...
Source: Preventive Veterinary Medicine - March 29, 2016 Category: Veterinary Research Source Type: research
Prevalence of Leishmania infantum and co-infections in stray cats in northern Italy.
Abstract
Stray cats in the city of Milan, Italy, were tested for Leishmania infantum and other selected infections. Twenty-seven cats (30.0%) were seroreactive by indirect fluorescent antibody test (IFAT), with an antibody titer of 1:40 for 16 (17.7%) cats and 1:80 (cut-off for feline L. infantum infection) for 11 (12.2%) cats. One blood (1.1%) and one popliteal lymph node (1.1%) sample tested positive by real-time polymerase chain reaction; no oculoconjunctival swabs tested positive. Feline immunodeficiency virus, feline leukemia virus, and feline coronavirus (FCoV) seroprevalence determined by enzyme-lin...
Source: Comparative immunology, microbiology and infectious diseases. - March 27, 2016 Category: Allergy & Immunology Authors: Spada E, Canzi I, Baggiani L, Perego R, Vitale F, Migliazzo A, Proverbio D Tags: Comp Immunol Microbiol Infect Dis Source Type: research
Molecular survey on zoonotic tick-borne bacteria and chlamydiae in feral pigeons (Columba livia domestica)
Conclusions Feral pigeons living in urban and periurban areas are a hazard for the human health as source of several pathogens. The obtained results confirm pigeons as reservoirs of chlamydial agents and suggest that they may be involved in the epidemiology of zoonotic tick-borne infections too. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - March 7, 2016 Category: Tropical Medicine Source Type: research
Prevalence of Leishmania infantum and co-infections in stray cats in northern Italy
Publication date: Available online 4 March 2016 Source:Comparative Immunology, Microbiology and Infectious Diseases Author(s): Eva Spada, Ilaria Canzi, Luciana Baggiani, Roberta Perego, Fabrizio Vitale, Antonella Migliazzo, Daniela Proverbio Stray cats in the city of Milan, Italy, were tested for Leishmania infantum and other selected infections. Twenty-seven cats (30.0%) were seroreactive by indirect fluorescent antibody test (IFAT), with an antibody titer of 1:40 for 16 (17.7%) cats and 1:80 (cut-off for feline L. infantum infection) for 11 (12.2%) cats. One blood (1.1%) and one popliteal lymph node (1....
Source: Comparative Immunology, Microbiology and Infectious Diseases - March 6, 2016 Category: Infectious Diseases Source Type: research
Comparison of serological methods with PCR-based methods for the diagnosis of community-acquired pneumonia caused by atypical bacteria
The diagnosis of community-acquired pneumonia (CAP) caused by Legionella pneumophila, Mycoplasma pneumoniae, and Chlamydophila pneumoniae is traditionally based on cultures and serology, which have special requir... (Source: Journal of Negative Results in BioMedicine)
Source: Journal of Negative Results in BioMedicine - March 2, 2016 Category: Research Authors: Mariana Herrera, Yudy Alexandra Aguilar, Zulma Vanessa Rueda, Carlos Muskus and Lázaro Agustín Vélez Source Type: research
Lower-leg cellulitis-like manifestations of erythema nodosum induced by Chlamydophila pneumoniae infection
Takahiro Sawada, Mitsuhiro Suehiro, Kiho TakayaIndian Journal of Dermatology 2016 61(2):237-237 (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - March 1, 2016 Category: Dermatology Authors: Takahiro SawadaMitsuhiro SuehiroKiho Takaya Source Type: research
Post-vaccination MDEM associated with MOG antibody in a subclinical Chlamydia infected boy
In this report, we describe the case of a 6-year-old Japanese boy who had multiphasic disseminated encephalomyelitis (MDEM), and was positive for both anti-myelin oligodendrocyte glycoprotein (MOG) antibodies and Chlamydophila pneumoniae antibodies. After vaccinations that were the second one for measles and rubella, and the booster immunization for Japanese encephalitis, the patient presented with fever, headache, vomiting, and a change in personality. (Source: Brain and Development)
Source: Brain and Development - February 24, 2016 Category: Neurology Authors: Kohji Azumagawa, Shohei Nomura, Yasushi Shigeri, Leslie Sargent Jones, Douglas Kazutoshi Sato, Ichiro Nakashima, Mitsuru Kashiwagi, Takuya Tanabe, Shuichi Shimakawa, Hideto Nakajima, Hiroshi Tamai Tags: Case Report Source Type: research
