Persons with allergy symptoms use alternative medicine more often.
CONCLUSIONS: The occurrence of allergic diseases and asthma influences the frequency of alternative medicine use. However the frequency of alternative medicine use does not depend on allergic disease or asthma being confirmed by a doctor. PMID: 27672066 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Kłak A, Raciborski F, Krzych-Fałta E, Opoczyńska-Świeżewska D, Szymański J, Lipiec A, Piekarska B, Sybilski A, Tomaszewska A, Samoliński B Tags: Pneumonol Alergol Pol Source Type: research

Effect of obesity and metabolic syndrome on severity, quality of life, sleep quality and inflammatory markers in patients of asthma in India.
Abstract INTRODUCTION: The study aimed to compare the effect of obesity with and without metabolic syndrome on asthma severity, quality of life, sleep quality, sleep disordered breathing and inflammatory markers as compared to non-obese asthma patients. MATERIAL AND METHODS: 60 asthma patients recruited for the study were divided equally into non-obese (NOA), obese without metabolic syndrome (OANMS) and obese with metabolic syndrome (OAMS) groups. Study cohorts were assessed for severity of asthma, quality of life and quality of sleep using questionnaires and inflammatory markers (FENO, hs-CRP, IL-5, IL-6 and...
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Singh M, Gupta N, Kumar R Tags: Pneumonol Alergol Pol Source Type: research

Centrilobular nodules in high resolution computed tomography of the lung in IPAH patients - preliminary data concerning clinico-radiological correlates.
CONCLUSION: Centrilobular nodules in IPAH were combined with lack of PFO, higher mRAP and younger age of patients. PMID: 27672068 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Szturmowicz M, Kacprzak A, Burakowska B, Skoczylas A, Bestry I, Kuś J, Fijałkowska A, Torbicki A, Kurzyna M Tags: Pneumonol Alergol Pol Source Type: research

The incidence of tuberculosis transmission among family members and outside households.
CONCLUSIONS: The analysis confirmed the transmission of tuberculosis among members of 53 families. In the remaining 6 families the source of infection were people outside the households. In all families with young children, strains isolated from them have identical DNA patterns as strains obtained from their adult caregivers. To confirm the transmission of TB in the study population of patients, epidemiological analysis required the addition of a genotyping methods characterised by high discriminatory power. PMID: 27672069 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Kozińska M, Augustynowicz-Kopeć E Tags: Pneumonol Alergol Pol Source Type: research

Musculosceletal tuberculosis with involvement of tendon sheaths and formation of synovial cyst.
We present a case of patient on immunosuppressive therapy due to myositis, in whom we diagnosed musculoskeletal tuberculosis in form of involvement of tendon sheath and formation of synovial cyst. PMID: 27672070 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Zieliński M, Mazur-Zielińska H, Kozielski J Tags: Pneumonol Alergol Pol Source Type: research

Hemoptysis in a patient with multifocal primary pulmonary angiosarcoma.
We present a case report of 70 year-old man, active cigarette-smoker, with a 2-month history of non-massive hemoptysis. The thorax CT revealed several solid pulmonary nodules surrounded by areas of ground glass opacity. As bronchoscopy failed to deliver adequate tissue samples, video assisted thoracic surgery (VATS) with pleura and lung biopsy was necessary. Histopathological findings were consistent with pulmonary angiosarcoma. Since no extrapulmonary lesions were demonstrated, the final diagnosis of primary pulmonary angiosarcoma was made. The patient died three months after the onset of symptoms. Our case report highlig...
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Piechuta A, Przybyłowski T, Szołkowska M, Krenke R Tags: Pneumonol Alergol Pol Source Type: research

The role of the TGF-SMAD signalling pathway in the etiopathogenesis of severe asthma.
Abstract Asthma is a chronic inflammatory heterogeneous disease of the lower respiratory tract characterised by the occurrence of bronchial hyper-responsiveness and paroxysmal, changeable bronchial obstruction. Transforming growth factor-beta (TGF-b) is one of the cytokines involved in mediating airway inflammation and remodelling. The level of TGF-b1 gene expression correlates with severity of symptoms. Alterations in the main SMAD signal transmission, overexpression of TGF-b genes and changes in the transcriptome cause excessive secretion of TGF-b and its increased expression in target cells, which clinically in...
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Koćwin M, Jonakowski M, Przemęcka M, Zioło J, Panek M, Kuna P Tags: Pneumonol Alergol Pol Source Type: research

Obstructive sleep apnea syndrome and hypothyroidism - merely concurrence or causal association?
Abstract The prevalence of obstructive sleep apnea-hypopnea syndrome (OSAHS) ranges from 4 to 7% in men and from 2 to 5% in women. Its deleterious consequences such as traffic accidents, cardiovascular complications increasing morbidity and mortality, make it a major health problem. Apart from obesity (a major risk factor for OSAHS), hypothyroid patients are prone to reveal this phenotype. Although hypothyroidism seems an acknowledged risk factor for OSAHS, some authors report the lack of clinically relevant association. The argument partly depends on the increased prevalence of hypothyroidism in OSAHS patients, b...
Source: Pneumonologia i Alergologia Polska - September 28, 2016 Category: Respiratory Medicine Authors: Kuczyński W, Gabryelska A, Mokros Ł, Białasiewicz P Tags: Pneumonol Alergol Pol Source Type: research

Chronic obstructive pulmonary disease in Poland - a need for population-based epidemiological studies.
PMID: 27435345 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - July 22, 2016 Category: Respiratory Medicine Authors: Zejda J, Brożek G Tags: Pneumonol Alergol Pol Source Type: research

Quality of life in adults with cystic fibrosis: the Greek experience.
We report the health-related quality of life (HRQoL) in CF adult patients and correlate our findings with the patients' demographic characteristics. MATERIAL AND METHODS: The Cystic Fibrosis Quality of Life (CFQoL) questionnaire was answered by 77 CF adult patients. The questionnaire included questions pertaining to age, sex and level of education and covered eight sections of functioning. RESULTS: The highest score was reported in the "Social Functioning" section, while the lowest in the "Concerns for the Future" section. When different age groups were compared, statistical significances were...
Source: Pneumonologia i Alergologia Polska - July 22, 2016 Category: Respiratory Medicine Authors: Stofa M, Xanthos T, Ekmektzoglou K, Chalkias A, Barouxis D, Pantazopoulos I, Iacovidou N Tags: Pneumonol Alergol Pol Source Type: research

Effects of depression and anxiety on asthma-related quality of life.
CONCLUSIONS: Anxiety and depression are found in asthma patients, with higher severity observed in patients with uncontrolled asthma. Female gender, the level of asthma control, asthma severity, smoking, as well as diagnoses of anxiety and depression are predictors of a significantly lower quality of life in asthma. PMID: 27435347 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - July 22, 2016 Category: Respiratory Medicine Authors: Lomper K, Chudiak A, Uchmanowicz I, Rosińczuk J, Jankowska-Polanska B Tags: Pneumonol Alergol Pol Source Type: research

Can pancreatic tissue cause haemoptysis?
Abstract A mature teratoma is a tumour of primary germ cells. It is often found in the mediastinum. The authors describe a case of a young man who demonstrated haemoptysis as the only symptom of a mediastinal tumour. The tumour was removed operatively, sent for histopathological examination and immunohistochemistry. The removed tumour was a mature teratoma including elements of the pancreas. The authors revealed the presence of trypsin in the pancreatic acinar cells. The proteolytic activity of the tumour was taken as the cause of haemoptysis because of enzymatic erosion of lung tissue intimately attached to the t...
Source: Pneumonologia i Alergologia Polska - July 22, 2016 Category: Respiratory Medicine Authors: Bubel A, Rogoziński P, Bruliński K Tags: Pneumonol Alergol Pol Source Type: research

The pharmaceutical care in asthma - Polish and global perspective.
Abstract The pharmaceutical care is a pharmacist's contribution to the care of individual patients and leads to optimize the use of drugs. The pharmaceutical care may improve adherence, clinical effectiveness of providing therapy and improve the health-related quality of life. The conducted literature review confirmed that pharmaceutical care and advanced pharmaceutical services are clinical effective in asthma. The implementation of pharmaceutical care under Polish conditions is currently insufficient and remains challenging for the future. Herein we should admit, that the polish government has recently put an ef...
Source: Pneumonologia i Alergologia Polska - July 22, 2016 Category: Respiratory Medicine Authors: Swieczkowski D, Poniatowski P, Merks P, Jaguszewski M Tags: Pneumonol Alergol Pol Source Type: research

The effect of omalizumab on eosinophilic inflammation of the respiratory tract in patients with allergic asthma.
Abstract Bronchial asthma is characterised by high levels of immunoglobulin E (IgE) and overproduction of pro-inflammatory cytokines, including interleukins IL-4, IL-13 and IL-5 needed for, amongst other things, the production of IgE and the differentiation, maturation, migration and survival of eosinophils. Eosinophils are one of the most important cells in allergic inflammation. Their presence in tissue is linked to the persistence of inflammatory infiltrate, tissue damage and remodelling. Although these cells are very sensitive to corticosteroids, some asthmatic patients do not respond to high doses of these dr...
Source: Pneumonologia i Alergologia Polska - July 22, 2016 Category: Respiratory Medicine Authors: Kupryś-Lipińska I, Molińska K, Kuna P Tags: Pneumonol Alergol Pol Source Type: research

Fatigue syndrome in sarcoidosis.
ki WJ Abstract Sarcoidosis is an inflammatory disease of unknown etiology. Most commonly it results in the formation of non-caseating granulomas in intrathoracic lymph nodes and lung parenchyma, but the clinical course and picture may be complicated by extrapulmonary involvement and many non-respiratory signs and symptoms which are directly related to the disease. In addition, sarcoidosis patients may suffer from a plethora of symptoms of uncertain or unknown origin. Fatigue is one of these symptoms, and according to some authors it is reported by the majority of patients with active sarcoidosis, but also by a sma...
Source: Pneumonologia i Alergologia Polska - July 22, 2016 Category: Respiratory Medicine Authors: Górski W, Piotrowski WJ Tags: Pneumonol Alergol Pol Source Type: research

The clinical differences of asthma in patients with molds allergy.
Abstract INTRODUCTION: Bronchial asthma is an increasing problem worldwide. The course of bronchial asthma is dependent on the type of inducing allergens. The differences between the clinical features of asthma in patients with monovalent allergies to molds and with other allergies were explored. MATERIAL AND METHODS: Randomly selected 1910 patients (924 women and 986 men) between 18-86 years in age were analyzed according to type of allergy and asthma. The diagnosis of asthma was confirmed on the basis of GINA criteria, physical examination and spirometry. Allergy diagnosis was confirmed on the basis of medi...
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Kołodziejczyk K, Bożek A, Jarząb J, Gawlik R Tags: Pneumonol Alergol Pol Source Type: research

Low DLCO in idiopathic pulmonary arterial hypertension - clinical correlates and prognostic significance.
Abstract INTRODUCTION: Decreased diffusing capacity of the lung for carbon monoxide (DLCO) is observed in some idiopathic pulmonary arterial hypertension (IPAH) patients, but its clinical significance is uncertain. We aimed to assess clinical correlates and prognostic significance of low DLCO in IPAH patients. MATERIAL AND METHODS: In the group of 65 IPAH patients the cut off value for low DLCO was set up based on histogram as
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Szturmowicz M, Kacprzak A, Franczuk M, Burakowska B, Kurzyna M, Fijałkowska A, Skoczylas A, Wesołowski S, Kuś J, Torbicki A Tags: Pneumonol Alergol Pol Source Type: research

Prospective, population-based surveillance of the burden of Streptococcus pneumoniae in community-acquired pneumonia in older adults, Chrzanów County, Poland, 2010 to 2012.
CONCLUSIONS: CAP due to PCV13 serotypes is a source of morbidity among adults>50 years and may be reduced by greater access to pneumococcal vaccines. PMID: 27238167 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Harat R, Alexander R, Gray S, Gutterman EM, Pluta J, Pride M, Shite S, Fijolek J, Kozub J Tags: Pneumonol Alergol Pol Source Type: research

Lifestyle factors and asthma in India - a case-control study.
Abstract INTRODUCTION: There has been a recent trend of increasing prevalence of asthma in developing countries; prevalence in the Indian population is reported to be 2%. The link between lifestyle factors and asthma has been mostly derived from western literature. The present study intended to study relationship if any, between life style factors and asthma in a representative Indian population. MATERIAL AND METHODS: The study is a case-control study performed for a period of one year, between 2014 and 2015. 125 asthma and correspondingly age and sex matched healthy controls were recruited for the purpose of...
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Poongadan MN, Gupta N, Kumar R Tags: Pneumonol Alergol Pol Source Type: research

Primary ciliary dyskinesia in six patients with bronchiectasis.
CONCLUSIONS: PCD should be considered as a probable underlying disorder in patients with bronchiectasis. Past medical history of otitis media and history of similar clinical findings in family members should raise suspicion toward PCD. PMID: 27238169 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Modaresi M, Sadeghi B, Mohammadinejad P, Sayedi SJ, Masiha F, Shirzadi R, Azizi G, Aghamohammadi A Tags: Pneumonol Alergol Pol Source Type: research

Diffuse Idiopathic Skeletal Hyperostosis (DISH) and non small cell lung cancer: case presentation and review of the literature.
Abstract Diffuse idiopathic skeletal hyperostosis (DISH), also known as Forestier's disease, is a systemic non inflammatory disease of unknown cause. It is characterized by the presence of osteophytes due to calcification and ossification of spinal ligaments and entheses. Moreover, diffuse idiopathic skeletal hyperostosis has been associated with a variety of metabolic disorders. However, to the best of our knowledge no association with non small cell lung cancer (NSCLC) has been reported so far. In the present study we report a case of a patient with NSCLC and DISH. PMID: 27238170 [PubMed - in process] (Sour...
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Tomos I, Vlami A, Karakatsani A, Korbila I, Manali ED, Papiris SA Tags: Pneumonol Alergol Pol Source Type: research

Cough-induced lung intercostal hernia.
Abstract A 73-year-old male with marked emphysema was admitted to the 2nd Department of Internal Medicine, University Hospital in Krakow because of chronic obstructive pulmonary disease (COPD) exacerbation. His medical history was significant for total laryngectomy due to laryngeal cancer in 2010. PMID: 27238171 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Kosałka J, Wawrzycka-Adamczyk K, Jurkiewicz P, Pawlik W, Milewski M, Musiał J Tags: Pneumonol Alergol Pol Source Type: research

A case of systemic melioidosis: unravelling the etiology of chronic unexplained fever with multiple presentations.
We report a case of systemic melioidosis in a 58-year-old diabetic, occupationally-unexposed male patient, who presented with chronic fever, sepsis, pneumonia, pleural effusion and subcutaneous abscess, was undiagnosed for long, misidentified as Pseudomonas aeruginosa infection elsewhere, but was saved due to correct identification of the etiologic agent and timely institution of appropriate therapy at our institute. A strong clinical and microbiological suspicion for melioidosis should be considered in the differential diagnosis of acute pyrexia of unknown origin, acute respiratory distress syndrome and acute onset of sep...
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Mohanty S, Pradhan G, Panigrahi MK, Mohapatra PR, Mishra B Tags: Pneumonol Alergol Pol Source Type: research

What factors may influence epidemiological situation of tuberculosis in Poland and in the world?
Abstract The authors present the review of factors influencing epidemiological situation of tuberculosis in Poland and in the world. The groups of increased risk of tuberculosis, and clinical conditions predisposing to activation of latent tuberculosis infection (LTBI) such as HIV, uremia, diabetes mellitus, transplantation of organs, treatment with glucocorticosteroids and with antibodies to TNF and to its receptors, were presented. The higher prevalence and worse prognosis of tuberculosis in elderly people was emphasised. The methods of LTBI recognition, according to recent recommendations, with special consider...
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Rowińska-Zakrzewska E, Korzeniewska-Koseła M, Augustynowicz-Kopeć E, Szturmowicz M Tags: Pneumonol Alergol Pol Source Type: research

Methods of airway resistance assessment.
Abstract Airway resistance is the ratio of driving pressure to the rate of the airflow in the airways. The most frequent methods used to measure airway resistance are whole-body plethysmography, the interrupter technique and the forced oscillation technique. All these methods allow to measure resistance during respiration at the level close to tidal volume, they do not require forced breathing manoeuvres or deep breathing during measurement. The most popular method for measuring airway resistance is whole-body plethysmography. The results of plethysmography include among others the following parameters: airway res...
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Urbankowski T, Przybyłowski T Tags: Pneumonol Alergol Pol Source Type: research

Tumor necrosis factor alpha as an asthma biomarker in early childhood.
PMID: 27238175 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Majak P Tags: Pneumonol Alergol Pol Source Type: research

Prognostic value of TH1/TH2 cytokines in infants with wheezing in a three year follow-up study.
CONCLUSION: We have identified TNF-a, as a biomarker, which can be detected in children under 3 years of age and may be useful in the prediction of development of persistence of wheezing later. To further evaluate the usefulness of this and other markers and establish cutoff levels for prediction and use in clinical practice, a larger prospective follow-up study is needed. PMID: 27238176 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Chkhaidze I, Zirakishvili D, Shavshvishvili N, Barnabishvili N Tags: Pneumonol Alergol Pol Source Type: research

Fungal infection of cystic fibrosis patients - single center experience.
CONCLUSIONS: A. fumigatus and C. albicans were the most common etiological agents of fungal respiratory pathogens associated with CF patients. A. fumigatus strains were in vitro 100% susceptible to azole and amphotericin B. Two strains of C. albicans and one strain of C. tropicalis were non-susceptible to azole (fluconazole, itraconazole and voriconazole). Scedosporium apiospermum was resistant to amphotericin B (MIC> 32 mg/l) and susceptible to voriconazole (MIC 0.094 mg/l). PMID: 27238177 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Garczewska B, Jarzynka S, Kuś J, Skorupa W, Augustynowicz-Kopeć E Tags: Pneumonol Alergol Pol Source Type: research

Dietary pattern and asthma in India.
CONCLUSION: Consumption of fast food, salted snacks, fried snacks, fats and oils nuts, dry fruits, carbonated drinks may be associated with asthma in India. Hence, it is imperative to reduce consumption and increase awareness of influence of fast food on asthma through public health policies. PMID: 27238178 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Poongadan MN, Gupta N, Kumar R Tags: Pneumonol Alergol Pol Source Type: research

Association of interleukins genes polymorphisms with multi-drug resistant tuberculosis in Ukrainian population.
CONCLUSIONS: Heterozygous genotype and mutations homozygous genotypes gene in polymorphisms determining specified cytokines' production is a PT risk factor and may lead to disease progression into chronic phase. Heterozygous genotype of aforementioned cytokine genetic polymorphisms was significantly the most frequent in patients with MDR TB. PMID: 27238179 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Butov DO, Kuzhko MM, Makeeva NI, Butova TS, Stepanenko HL, Dudnyk AB Tags: Pneumonol Alergol Pol Source Type: research

A case of DIPNECH presenting as usual interstitial pneumonia.
We present a case of patient with DIPNECH manifesting with restrictive pattern and as usual interstitial pneumonia on imaging. PMID: 27238180 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Chatterjee K, Kamimoto JJ, Dunn A, Mittadodla E, Joshi M Tags: Pneumonol Alergol Pol Source Type: research

Pulmonary mycotic pseudo-aneurysm with a prior history of ventricular septal defect. Case report with review of literature.
We report a 7 year old female with two right-sided parahilar pseudo-aneurysm of fungal origin with a prior history of ventricular septal defect. Pulmonary mycotic pseudo-aneurysms are very rare and require a high suspicion to diagnose. If a patient is still symptomatic for fever and cough for a long time, and consolidation on x-ray is not improving on antibiotics, contrast-enhanced computed tomography is indicated. It can be suspected that the "friable mass attached to ventricular septal defect patch" was a source of fungeal emboli to pulmonary arteries thus giving weight to the infective endocarditis etiology. A...
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Walasangikar V, Kumar Dey A, Sharma R, Murumkar V, Gadewar R, Hira P, Mittal K Tags: Pneumonol Alergol Pol Source Type: research

Comorbidities in lung cancer.
Abstract Comorbidity is the occurrence of concomitant disease in addition to an index disease of interest or the simultaneous occurrence of multiple diseases in an individual. Lung cancer is associated with age and smoking, and both age and smoking are strongly associated with comorbidity. Lung cancer is the most common malignancy in the world. Comorbidity, such as diseases of cardiovascular, pulmonary and other systems may influence prognosis in lung cancer as well as complicate its treatment. In this paper we tried to conclude the significance of the individual comorbidities in lung cancer and their impact on pa...
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Dutkowska AE, Antczak A Tags: Pneumonol Alergol Pol Source Type: research

Standards for diagnosis and care of patients with inherited alpha-1 antitrypsin deficiency Recommendations of the Polish Respiratory Society, Polish Society of Pediatric Pulmonology and Polish Society of Pediatric Gastroenterology.
PMID: 27238183 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - June 1, 2016 Category: Respiratory Medicine Authors: Chorostowska-Wynimko J, Bakuła A, Kulus M, Kuca P, Niżankowska-Mogilnicka E, Sanak M, Socha P, Śliwiński P Tags: Pneumonol Alergol Pol Source Type: research

Aspergilloma in atypical localisation in severe asthma patient - case report.
Abstract Pulmonary aspergillosis is a condition caused by the fungi Aspergillus. The form of disease depends on the immunological condition of the host organism and other concomitant illnesses that influence the pulmonary tissue. Asthmatic patients, in particular with the severe form of disease, who require the use of systemic glucocorticoids, are predisposed to develop allergic bronchopulmonary aspergillosis. Development of aspergilloma in the lung is preceded by the formation of pathological cavity in the course of another illness. The study reports a case of a severe asthma patient who developed aspergilloma in...
Source: Pneumonologia i Alergologia Polska - March 11, 2016 Category: Respiratory Medicine Authors: Zieliński M, Ziora D, Mazur-Zielińska H Tags: Pneumonol Alergol Pol Source Type: research

Macrolide antibiotics in respiratory diseases. Recommendations of the Polish Expert Group - AD 2015.
PMID: 26922898 [PubMed - as supplied by publisher] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - March 2, 2016 Category: Respiratory Medicine Authors: Emeryk A, Mazurek H, Pirożyński M, Klatka J, Służewski W, Antczak A, Bartkowiak-Emeryk M, Kowalska M, Dutkowska A Tags: Pneumonol Alergol Pol Source Type: research

European Spirometry Driving License in Poland - first polish spirometry training in the framework of ERS HERMES Spirometry project.
PMID: 26806416 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 26, 2016 Category: Respiratory Medicine Authors: Tomalak W, Franczuk M, Kuca P, Czajkowska-Malinowska M Tags: Pneumonol Alergol Pol Source Type: research

Typing safe antibiotics in amoxicillin hypersensitive patients - development of a stepwise protocol.
CONCLUSION: A stepwise approach including SPTs, ICTs and provocations with amoxicillin / cefuroxime/macrolide - depending on a patient's history - is safe and allows typing an antibiotic in the vast majority of patients. PMID: 26806417 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - January 26, 2016 Category: Respiratory Medicine Authors: Specjalski K, Kita-Milczarska K, Chełmińska M, Jassem E Tags: Pneumonol Alergol Pol Source Type: research

Pulmonary lesions in the course of gastric cancer - two cases of Bard's syndrome.
Abstract The Bard's syndrome is a medical condition related to miliary dissemination of gastric cancer to the lungs. Difficulties in diagnosis are associated with the need of differentiation between numerous diseases, which may manifest as disseminated lesions in the lung parenchyma on chest X-ray. Despite the advanced proliferative process, primary focus of neoplasm frequently remains subclinical. Metastatic lesions cause many symptoms in the respiratory system, suggesting primary pulmonary pathology. The Bard's syndrome should be always taken into account in differential diagnosis of disseminated lesions, partic...
Source: Pneumonologia i Alergologia Polska - January 26, 2016 Category: Respiratory Medicine Authors: Zieliński M, Ochman M, Głowacki J, Kozielski J Tags: Pneumonol Alergol Pol Source Type: research

Pulmonary arterial hypertension: a current review of pharmacological management.
Abstract Pulmonary hypertension (PHTN) is a rare and devastating disease characterized by progressive increases in pulmonary arterial pressure and pulmonary vascular resistance, which eventually leads to right ventricular failure and death. At present there is no cure for pulmonary arterial hypertension (PAH); however over the past decade targeted pharmaceutical options have become available for the treatment of PAH. Prior to evaluation for therapeutic options a definitive diagnosis of pulmonary arterial hypertension must be made via comprehensive physical exam and definitive diagnostic testing. Screening test of ...
Source: Pneumonologia i Alergologia Polska - December 23, 2015 Category: Respiratory Medicine Authors: Sahni S, Ojrzanowski M, Majewski S, Talwar A Tags: Pneumonol Alergol Pol Source Type: research

Serum levels of apoptosis-related markers (sFasL, TNFalpha, p53 and bcl-2) in COPD patients.
CONCLUSIONS: We didn't observe any differences in serum levels of pro- and antiapoptotic markers in COPD patients and the control group or correlations between the markers studied and COPD parameters. PMID: 26687668 [PubMed - as supplied by publisher] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - December 21, 2015 Category: Respiratory Medicine Authors: Kosacka M, Porębska I, Korzeniewska A, Rubinsztajn R, Grabicki M, Jankowska R, Batura-Gabryel H, Chazan R Tags: Pneumonol Alergol Pol Source Type: research

Effect of disease acceptance on quality of life in patients with chronic obstructive pulmonary disease (COPD).
Abstract INTRODUCTION: Despite the advances in medicine, COPD is still leading, incurable and chronic respiratory disease. It greatly restricts the functioning of patients in terms of physical, emotional and social aspects, reducing significantly their quality of life. The study into quality of life in patients with COPD is becoming increasingly important as a valuable complement to the assessment of clinical status of the patient, the effects of therapy, effectiveness of educational programs, clinical evaluation of drugs, including the patient's acceptance of the disease and treatment. Acceptance or lack thereof,...
Source: Pneumonologia i Alergologia Polska - December 21, 2015 Category: Respiratory Medicine Authors: Jankowska-Polańska B, Kasprzyk M, Chudiak A, Uchmanowicz I Tags: Pneumonol Alergol Pol Source Type: research

Chronic cough as a symptom of laryngopharyngeal reflux - two case reports.
Abstract Laryngopharyngeal reflux (LPR) is a complex of symptoms caused by the backflow of gastric contents into the larynx, pharynx, nasopharynx, sinuses and even to the middle ear space.The symptomatology of LPR includes: chronic cough, hoarseness, throat clearing, laryngitis,"globus pharyngeus", swallowing disturbances, postnasal drip, "fetor ex ore".In the article, the authors present two boys with chronic cough, in one of them the asthma was suspected and antiasthmatic treatment was administrated; in our patients according to the 24-hour pharyngeal pH-metry LPR was diagnosed. The aim of th...
Source: Pneumonologia i Alergologia Polska - December 21, 2015 Category: Respiratory Medicine Authors: Stelmach I Tags: Pneumonol Alergol Pol Source Type: research

Usefulness of lung ultrasound in diagnosing causes of exacerbation in patients with chronic dyspnea.
Abstract Dyspnea is a non-specific symptom that requires fast diagnostics, accurate diagnosis and proper treatment. The most common causes of dyspnea include exacerbation of chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF). Distinction between these two medical conditions seems to be critical in diagnostics of emergencies. At the same time, basic diagnostic tools available in emergency room, such as classic radiography (X-ray) of the chest, electrocardiography (ECG) or b-type natriuretic peptide test, are sometimes ambiguous. Therefore looking for additional diagnostic tool seems to be ...
Source: Pneumonologia i Alergologia Polska - December 21, 2015 Category: Respiratory Medicine Authors: Rogoza K, Kosiak W Tags: Pneumonol Alergol Pol Source Type: research

Lung function in children with newly diagnosed connective tissue disease.
CONCLUSIONS: Lung function impairment is relatively common in children with CTDs. Although restrictive ventilatory pattern is considered typical feature of lung involvement in CTDs, airflow limitation could also be an initial abnormality. PMID: 26676969 [PubMed - as supplied by publisher] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - December 17, 2015 Category: Respiratory Medicine Authors: Peradzyńska J, Krenke K, Szylling A, Kołodziejczyk B, Gazda A, Rutkowska-Sak L, Kulus M Tags: Pneumonol Alergol Pol Source Type: research

[Was vascular ring the cause of dyspnea?].
PMID: 26619517 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - December 3, 2015 Category: Respiratory Medicine Authors: Zielonka TM Tags: Pneumonol Alergol Pol Source Type: research

Telemedicine for the management of COPD - near future or a hazy idea?
ski P PMID: 26559791 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - November 15, 2015 Category: Respiratory Medicine Authors: Piotrowski WJ, Górski P Tags: Pneumonol Alergol Pol Source Type: research

Change is in the air: bronchial valves to improve quality of life in heterogeneous emphysema.
PMID: 26559792 [PubMed - in process] (Source: Pneumonologia i Alergologia Polska)
Source: Pneumonologia i Alergologia Polska - November 15, 2015 Category: Respiratory Medicine Authors: Krenke R Tags: Pneumonol Alergol Pol Source Type: research

The influence of lung volume reduction with intrabronchial valves on the quality of life of patients with heterogeneous emphysema - a prospective study.
Abstract INTRODUCTION: A heterogeneous emphysema is one of the most severe forms of chronic obstructive pulmonary disease (COPD). In some cases, besides the standard pharmacotherapy, a new treatment option of emphysema can be used - bronchoscopic lung volume reduction (BLVR) with the use of intrabronchial valves. OBJECTIVES: To examine the health-related quality of life (HRQoL) of patients with severe emphysema after intrabronchial valve (IBV) implantation for the treatment of one lung. MATERIAL AND METHODS: From 2011 to 2013 a single centre prospective observational study was performed. The study assess...
Source: Pneumonologia i Alergologia Polska - November 15, 2015 Category: Respiratory Medicine Authors: Szlubowska S, Zalewska-Puchała J, Majda A, Kocoń P, Soja J, Gnass M, Pasko E, Ćmiel A, Szlubowski A, Kużdżał J Tags: Pneumonol Alergol Pol Source Type: research

Dynamics of body composition in male patients during chronic obstructive pulmonary disease (COPD) development.
Abstract INTRODUCTION: The various distribution of fat mass (FM) and lean mass (LM) during COPD development is not yet researched. MATERIAL AND METHODS: 82 male patients (40-67 years) with acute exacerbation of COPD and 19 comparable healthy males (the control group) were examined by dual-energy X-ray absorptiometry. The patients were divided into 3 groups according to COPD severity: 1st - 19 (GOLD I stage); 2nd - 43 (GOLD II) and 3rd - 20 (GOLD III). RESULTS: The patients of 3rd group had lower indices of FM, LM, bone mineral component (BMC) vs. the control and 1st, 2nd groups. A significant increase in...
Source: Pneumonologia i Alergologia Polska - November 15, 2015 Category: Respiratory Medicine Authors: Makarevich AE, Lemiasheuskaya S Tags: Pneumonol Alergol Pol Source Type: research