Post-vaccination MDEM associated with MOG antibody in a subclinical infected boy
In this report, we describe the case of a 6-year-old Japanese boy who had multiphasic disseminated encephalomyelitis (MDEM), and was positive for both anti-myelin oligodendrocyte glycoprotein (MOG) antibodies and Chlamydophila pneumoniae antibodies. After vaccinations that were the second one for measles and rubella, and the booster immunization for Japanese encephalitis, the patient presented with fever, headache, vomiting, and a change in personality. (Source: Brain and Development)
Source: Brain and Development - February 24, 2016 Category: Neurology Authors: Kohji Azumagawa, Shohei Nomura, Yasushi Shigeri, Leslie Sargent Jones, Douglas Kazutoshi Sato, Ichiro Nakashima, Mitsuru Kashiwagi, Takuya Tanabe, Shuichi Shimakawa, Hideto Nakajima, Hiroshi Tamai Tags: Case Report Source Type: research
Bacterial Sepsis Increases Survival in Metastatic Melanoma: Chlamydophila Pneumoniae Induces Macrophage Polarization and Tumor Regression
The initiative of this study was the unexpected complete tumor regression in a patient with stage IV cutaneous metastatic melanoma, who suffered multifactorial sepsis syndrome during BOLD (bleomycin, oncovin, lomustine, and dacarbazine) chemotherapy (see Supplementary Figure S1 online). After targeted antibiotic treatment and combined complication-free chemotherapy, the patient’s physical condition improved, and the metastases unexpectedly disappeared. The patient has been asymptomatic and metastasis-free since the end of BOLD therapy. (Source: Journal of Investigative Dermatology)
Source: Journal of Investigative Dermatology - December 29, 2015 Category: Dermatology Authors: Krisztina Buzás, Annamária Marton, Csaba Vizler, Edina Gyukity-Sebestyén, Mária Harmati, Katalin Nagy, Ágnes Zvara, Róbert L. Katona, Vilmos Tubak, Valéria Endrész, István B. Németh, Judit Oláh, László Vígh, Tamás Bíró, Lajos Kemény Tags: Letter to the editor Source Type: research
Postepy Hig Med Dosw 2015; 69:612-623 "Selected aspects of Chlamydophila pneumoniae infections"
Chlamydophila pneumoniae was taxonomically separated from strain TWAR – an abbreviation of the strain isolated from humans TW-183 (material from the eye of a child in Taiwan in 1965) and AR-39 (material from a student’s throat swab with acute changes within airways in Seattle in 1983). The basis of separation of the C. pneumoniae species was the unique structure of the elementary bodies.
Infection caused by C. pneumoniae is often asymptomatic (60-80% of all infections). Symptomatic infections of the upper respiratory tract relate to pharyngitis, laryngitis, sinusitis and the lower respiratory tract: bronchitis and pne...
Source: Postepy higieny i medycyny doswiadczalnej - December 22, 2015 Category: Research Tags: Review article Source Type: research
Dual infection of Mycoplasma pneumoniae and Chlamydophila pneumoniae in patients with atopic predispositions successfully treated by moxifloxacin.
We report two cases of dual infection with Mycoplasma pneumoniae and Chlamydophila pneumoniae complicated by atopic dermatitis or allergic rhinitis. After exacerbations of atopic eczema or rhinitis, both patients presented a nocturnal fever with persistent cough for more than two weeks. Although the use of susceptible antibiotics, such as minocycline or azithromycin, failed to work, moxifloxacin completely resolved their prolonged symptoms shortly after the administration together with a dramatic improvement of the atopic symptoms. Since the patients in question were predisposed to atopic disorders and their lymphocytes we...
Source: Infezioni in Medicina - December 12, 2015 Category: Infectious Diseases Tags: Infez Med Source Type: research
The adenoviral infections in children admitted to hospital with pneumonia, acute bronchiolitis or respiratory viral infections.
CONCLUSIONS: The percent of ADV infections in children hospitalized with acute respiratory infections (ARI) caused by neither RSV or hMPV is 14.2%. ADV is most frequently encountered in the 6 months - 2 years and then 2 - 5 years groups, but the most severe pneumonia forms can be seen in the 6 months - 2 years group. In children < 6 months with acute bronchiolitis ADV was not found to be an etiologic agent.
PMID: 22838216 [PubMed - indexed for MEDLINE] (Source: Roumanian Archives of Microbiology and Immunology)
Source: Roumanian Archives of Microbiology and Immunology - December 12, 2015 Category: Microbiology Tags: Roum Arch Microbiol Immunol Source Type: research
Detection of Chlamydophila psittaci from pigeons by polymerase chain reaction in Ahvaz.
CONCLUSIONS: In this research the pigeons were asymptomatic carriers for Cp. psittaci in their respiratory discharges. These results suggest that Cp. psittaci infection of human can occur in very close and continuous contact with pigeons.
PMID: 26644869 [PubMed - as supplied by publisher] (Source: Iranian Journal of Microbiology)
Source: Iranian Journal of Microbiology - December 12, 2015 Category: Microbiology Tags: Iran J Microbiol Source Type: research
Classification and Functional Analyses of Putative Conserved Proteins from Chlamydophila pneumoniae CWL029
Abstract
Chlamydophila pneumoniae, a Gram-negative bacterium belongs to the family Chlamydiaceae, is known to cause community-acquired pneumonia and bronchitis. There is a need for genomic analyses of C. pneumoniae as its chronic infections result in reactive airway disease, lung cancer and asthma. Recent advancement in the sequencing techniques led to the generation of large genomic data. In order to utilize these data, sequence-based function predictions were used for annotating the uncharacterized genes. The genome of C. pneumoniae encodes 1052 proteins, which include a grou...
Source: Interdisciplinary Sciences, Computational Life Sciences - December 9, 2015 Category: Bioinformatics Source Type: research
[MALT Lymphoma of the Conjunctiva in a 13-year old Child - 5-Year Relapse-free Follow-up Following Antibiotic Treatment].
Conclusion: We showed that extranodal MALT lymphomas of the conjunctiva can be successfully treated with antibiotics alone. At the start of therapy, the child was 13 years old. To our knowledge, this patient is the first child in Germany and one of the first in the world with ocular adnexal lymphoma who could be successfully treated with combined antibiotic therapy and who could be followed up for 5 years without relapse. Thus, we could avoid radiotherapy or chemotherapy in childhood and eliminate the risk of a therapy-induced secondary malignancy.
PMID: 26609671 [PubMed - as supplied by publisher] (Source: Klinisc...
Source: Klinische Monatsblatter fur Augenheilkunde - November 28, 2015 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research
Clinicopathologic characteristics and treatment of marginal zone lymphoma of mucosa‐associated lymphoid tissue (MALT lymphoma)
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Extranodal marginal zone lymphoma of the mucosa‐associated lymphoid tissue (MALT lymphoma) accounts for 7% to 8% of newly diagnosed lymphomas. Because of its association with infectious causes, such as Helicobacter pylori (HP) or Chlamydophila psittaci (CP), and autoimmune diseases, it has become the paradigm of an antigen‐driven malignancy. MALT lymphoma usually displays an indolent course, and watch‐and‐wait strategies are justified initially in a certain percentage of patients. In patients with gastric MALT lymphoma or ocular adnexal MALT lymphoma, antibiotic therapy against HP ...
Source: CA: A Cancer Journal for Clinicians - November 24, 2015 Category: Cancer & Oncology Authors: Markus Raderer, Barbara Kiesewetter, Andrés J. M. Ferreri Tags: Review Article Source Type: research
Feline calicivirus and other respiratory pathogens in cats with Feline calicivirus-related symptoms and in clinically healthy cats in Switzerland
Background:
Cats with feline calicivirus (FCV)-related symptoms are commonly presented to veterinary practitioners. Various clinical manifestations have been attributed to FCV, i.e. upper respiratory tract disease (URTD), oral ulcerations, gingivostomatitis, limping syndrome and virulent systemic disease. Additionally, healthy cats can shed FCV. The aims of this study were 1) to investigate the frequency of FCV in cats with FCV-related symptoms and in healthy cats in Switzerland, 2) to assess risk and protective factors for infection, such as signalment, housing conditions, vaccination, and co-infection with URTD-associate...
Source: BMC Veterinary Research - November 13, 2015 Category: Veterinary Research Authors: Alice BergerBarbara WilliMarina MeliFelicitas BorettiSonja HartnackAnou DreyfusHans LutzRegina Hofmann-Lehmann Source Type: research
Pneumonia in Vietnamese Children Aged 1 to 15 years Due to Atypical Pneumonia Causative Bacteria: Hospital-Based Microbiological and Epidemiological Characteristics.
Abstract
Pneumonia caused by Mycoplasma pneumoniae (M), Chlamydophila (Chlamydia) pneumoniae (C) and Legionella pneumophila (L) (these three bacteria are referred as the MCL, hereafter) is not well-documented in Vietnam, which may limit effectiveness of treatment. We investigated epidemiological & microbiological characteristics of MCL-caused pneumonia in hospitalized children aged 1-15 years.Multiplex PCR and specific IgM determination were used to detect the target bacteria. Of 722 community-acquired pneumonia (CAP) children, the MCL were the most frequently found pathogens (215 children, 29.78%). M....
Source: Japanese Journal of Infectious Diseases - November 13, 2015 Category: Infectious Diseases Authors: Huong PL, Hien PT, Lan NT, Binh TQ, Tuan DM, Anh DD Tags: Jpn J Infect Dis Source Type: research
Chlamydophila pneumoniae was rarely detected in bronchoalveolar lavage fluid in patients with bacterial pneumonia using molecular methods
Conclusions: No C. pneumoniae DNA was detected in BALF samples from patients with pneumonia, even though molecular modalities were applied. These results may suggest that C. pneumoniae may be extremely few in the lower respiratory tract in patients with pneumonia, and physicians may consider low possibility of C. pneumoniae as causative pathogen. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 30, 2015 Category: Respiratory Medicine Authors: Noguchi, S., Yatera, K., Kawanami, T., Fukuda, K., Yamasaki, K., Naito, K., Akata, K., Ishimoto, H., Taniguchi, H., Mukae, H. Tags: 10.1 Respiratory Infections Source Type: research
Viral and atypical bacterial aetiologies of infection in hospitalised patients admitted with clinical suspicion of influenza in Thailand, Vietnam and Indonesia
ConclusionRespiratory viruses were the most commonly detected pathogens in patients hospitalised with a clinical suspicion of influenza. Rhinovirus was the most frequently detected virus, and M. pneumoniae, the most common atypical bacterium. The low number of detected influenza viruses demonstrates a low benefit for empirical oseltamivir therapy, unless during an influenza outbreak. (Source: Influenza and Other Respiratory Viruses)
Source: Influenza and Other Respiratory Viruses - October 13, 2015 Category: Virology Authors: Heiman F. L. Wertheim, Behzad Nadjm, Sherine Thomas, Agustiningsih, Suhud Malik, Diep Ngoc Thi Nguyen, Dung Viet Tien Vu, Kinh Van Nguyen, Chau Vinh Van Nguyen, Liem Thanh Nguyen, Sinh Thi Tran, Thuy Bich Thi Phung, Trung Vu Nguyen, Tran Tinh Hien, Uyen H Tags: Original Article Source Type: research
Role of Atypical Pathogens and the Antibiotic Prescription Pattern in Acute Bronchitis: A Multicenter Study in Korea.
In conclusion, our study demonstrates that the incidence of atypical pathogens is low in patients with acute bronchitis, and the rate of antibiotic prescriptions is high.
PMID: 26425041 [PubMed - in process] (Source: Journal of Korean Medical Science)
Source: Journal of Korean Medical Science - October 2, 2015 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research
Volume: 22 Issue: 3
This study investigated the impact of a relatively inexpensive tool aimed to improve patient care and outcomes at a quaternary care academic hospital in Toronto, Ontario.
Bronchiectasis exacerbations: The role of atypical bacteria, respiratory syncytial virus and pulmonary function testsA significant proportion of bronchiectasis exacerbations may be explained by chronic colonization of the lower respiratory tract by <span style="font-style: italic">Haemophilus influenzae</span> and <span style="font-style: italic">Pseudomonas</span> species. Less studied, however, is the involvem...
Source: Canadian Respiratory Journal - August 15, 2015 Category: Respiratory Medicine Source Type: research
