Pneumonia in Vietnamese Children Aged 1 to 15 years Due to Atypical Pneumonia Causative Bacteria: Hospital-Based Microbiological and Epidemiological Characteristics.

Pneumonia in Vietnamese Children Aged 1 to 15 years Due to Atypical Pneumonia Causative Bacteria: Hospital-Based Microbiological and Epidemiological Characteristics. Jpn J Infect Dis. 2015 Nov 13; Authors: Huong PL, Hien PT, Lan NT, Binh TQ, Tuan DM, Anh DD Abstract Pneumonia caused by Mycoplasma pneumoniae (M), Chlamydophila (Chlamydia) pneumoniae (C) and Legionella pneumophila (L) (these three bacteria are referred as the MCL, hereafter) is not well-documented in Vietnam, which may limit effectiveness of treatment. We investigated epidemiological & microbiological characteristics of MCL-caused pneumonia in hospitalized children aged 1-15 years.Multiplex PCR and specific IgM determination were used to detect the target bacteria. Of 722 community-acquired pneumonia (CAP) children, the MCL were the most frequently found pathogens (215 children, 29.78%). M. pneumoniae was the most common at 88.4% (190/215), the typing based on p1 gene for cytoadhesin were both type I and type II, 51% and 28%, respectively. Age is an important factor: more than 77% (167/215) of MCL pneumonia was found in children less than 5 years of age and a high rate (66%; 64/97) of M-caused severe pneumonia cases was in children younger than 2 years. The distribution of MCL-caused pneumonia by age was a statistically significant (P < 0.01). In Vietnam, pneumonia due to M. pneumoniae in younger children must be interested and appropriately considered in diagno...
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research