Implications of Microorganisms in Alzheimer's Disease
Curr Issues Mol Biol. 2022 Sep 30;44(10):4584-4615. doi: 10.3390/cimb44100314.ABSTRACTAlzheimer's disease (AD) is a deadly brain degenerative disorder that leads to brain shrinkage and dementia. AD is manifested with hyperphosphorylated tau protein levels and amyloid beta (Aβ) peptide buildup in the hippocampus and cortex regions of the brain. The nervous tissue of AD patients also contains fungal proteins and DNA which are linked to bacterial infections, suggesting that polymicrobial infections also occur in the brains of those with AD. Both immunohistochemistry and next-generation sequencing (NGS) techniques were employ...
Source: Current Issues in Molecular Biology - October 26, 2022 Category: Molecular Biology Authors: Pardeep Yadav Yeon-Hee Lee Hrithika Panday Shubham Kant Neha Bajwa Ritika Parashar Saurabh Kumar Jha Niraj Kumar Jha Parma Nand Sang-Soo Lee Abhimanyu Kumar Jha Source Type: research
The Application Value of Metagenomic and Whole-Genome Capture Next-Generation Sequencing in the Diagnosis and Epidemiological Analysis of Psittacosis
ConclusionSignificant advantages of mNGS with normal datasets were demonstrated in early diagnosing psittacosis. It is the first study to use whole-genome capture to analyze C. psittaci epidemiological information. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - June 6, 2022 Category: Microbiology Source Type: research
Rhinovirus as the main co-circulating virus during the COVID-19 pandemic in children
CONCLUSION: During the period of social distancing in response to COVID-19, the prevalence of most respiratory pathogens was unusually low. Rhinovirus remained as the main virus co-circulating with SARS-CoV-2. COVID-19 in symptomatic children was less associated with hospitalization than with other respiratory infections in children and adolescents.PMID:35490727 | PMC:PMC9015957 | DOI:10.1016/j.jped.2022.03.003 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - May 1, 2022 Category: Pediatrics Authors: Fernanda Hammes Varela Ivaine Tais Sauthier Sartor M árcia Polese-Bonatto Tha ís Raupp Azevedo Luciane Beatriz Kern Tiago Fazolo Caroline Nespolo de David Gabriela Oliveira Zavaglia Ingrid Rodrigues Fernandes Jo ão Ronaldo Mafalda Krauser Renato T Stei Source Type: research
Rhinovirus as the main co-circulating virus during the COVID-19 pandemic in children
CONCLUSION: During the period of social distancing in response to COVID-19, the prevalence of most respiratory pathogens was unusually low. Rhinovirus remained as the main virus co-circulating with SARS-CoV-2. COVID-19 in symptomatic children was less associated with hospitalization than with other respiratory infections in children and adolescents.PMID:35490727 | PMC:PMC9015957 | DOI:10.1016/j.jped.2022.03.003 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - May 1, 2022 Category: Pediatrics Authors: Fernanda Hammes Varela Ivaine Tais Sauthier Sartor M árcia Polese-Bonatto Tha ís Raupp Azevedo Luciane Beatriz Kern Tiago Fazolo Caroline Nespolo de David Gabriela Oliveira Zavaglia Ingrid Rodrigues Fernandes Jo ão Ronaldo Mafalda Krauser Renato T Stei Source Type: research
Rhinovirus as the main co-circulating virus during the COVID-19 pandemic in children
CONCLUSION: During the period of social distancing in response to COVID-19, the prevalence of most respiratory pathogens was unusually low. Rhinovirus remained as the main virus co-circulating with SARS-CoV-2. COVID-19 in symptomatic children was less associated with hospitalization than with other respiratory infections in children and adolescents.PMID:35490727 | PMC:PMC9015957 | DOI:10.1016/j.jped.2022.03.003 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - May 1, 2022 Category: Pediatrics Authors: Fernanda Hammes Varela Ivaine Tais Sauthier Sartor M árcia Polese-Bonatto Tha ís Raupp Azevedo Luciane Beatriz Kern Tiago Fazolo Caroline Nespolo de David Gabriela Oliveira Zavaglia Ingrid Rodrigues Fernandes Jo ão Ronaldo Mafalda Krauser Renato T Stei Source Type: research
Rhinovirus as the main co-circulating virus during the COVID-19 pandemic in children
CONCLUSION: During the period of social distancing in response to COVID-19, the prevalence of most respiratory pathogens was unusually low. Rhinovirus remained as the main virus co-circulating with SARS-CoV-2. COVID-19 in symptomatic children was less associated with hospitalization than with other respiratory infections in children and adolescents.PMID:35490727 | DOI:10.1016/j.jped.2022.03.003 (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - May 1, 2022 Category: Pediatrics Authors: Fernanda Hammes Varela Ivaine Tais Sauthier Sartor M árcia Polese-Bonatto Tha ís Raupp Azevedo Luciane Beatriz Kern Tiago Fazolo Caroline Nespolo de David Gabriela Oliveira Zavaglia Ingrid Rodrigues Fernandes Jo ão Ronaldo Mafalda Krauser Renato T Stei Source Type: research
Seasonal predominance of atypical agents in adult community-acquired pneumonia in India's northeastern region: Is it the time to look again at empirical therapy guidelines?
Trop Doct. 2022 Feb 28:494755221080587. doi: 10.1177/00494755221080587. Online ahead of print.ABSTRACTAtypical agents such as Mycoplasma, Legionella, Chlamydia species, and Coxiella burnetii (Q-fever agent) are responsible for some adult community-acquired pneumonia (CAP). Insufficient studies on this topic can be blamed for the failure to include atypical pathogens in empirical management. We followed adult CAP cases for two years, and samples (respiratory and serum) were tested by culture, ELISA (IgM, IgG, and IgA), and PCR. A risk factor analysis was performed. Overall in 21.3% adult CAP patients, atypical agents found ...
Source: Tropical Doctor - February 28, 2022 Category: Tropical Medicine Authors: Deepjyoti Kalita Sangeeta Deka Kripesh Ranjan Sharma Ridip Kumar Sarma Naba Kumar Hazarika Source Type: research
Seasonal predominance of atypical agents in adult community-acquired pneumonia in India's northeastern region: Is it the time to look again at empirical therapy guidelines?
Trop Doct. 2022 Feb 28:494755221080587. doi: 10.1177/00494755221080587. Online ahead of print.ABSTRACTAtypical agents such as Mycoplasma, Legionella, Chlamydia species, and Coxiella burnetii (Q-fever agent) are responsible for some adult community-acquired pneumonia (CAP). Insufficient studies on this topic can be blamed for the failure to include atypical pathogens in empirical management. We followed adult CAP cases for two years, and samples (respiratory and serum) were tested by culture, ELISA (IgM, IgG, and IgA), and PCR. A risk factor analysis was performed. Overall in 21.3% adult CAP patients, atypical agents found ...
Source: Tropical Doctor - February 28, 2022 Category: Tropical Medicine Authors: Deepjyoti Kalita Sangeeta Deka Kripesh Ranjan Sharma Ridip Kumar Sarma Naba Kumar Hazarika Source Type: research
Seasonal predominance of atypical agents in adult community-acquired pneumonia in India's northeastern region: Is it the time to look again at empirical therapy guidelines?
Trop Doct. 2022 Feb 28:494755221080587. doi: 10.1177/00494755221080587. Online ahead of print.ABSTRACTAtypical agents such as Mycoplasma, Legionella, Chlamydia species, and Coxiella burnetii (Q-fever agent) are responsible for some adult community-acquired pneumonia (CAP). Insufficient studies on this topic can be blamed for the failure to include atypical pathogens in empirical management. We followed adult CAP cases for two years, and samples (respiratory and serum) were tested by culture, ELISA (IgM, IgG, and IgA), and PCR. A risk factor analysis was performed. Overall in 21.3% adult CAP patients, atypical agents found ...
Source: Tropical Doctor - February 28, 2022 Category: Tropical Medicine Authors: Deepjyoti Kalita Sangeeta Deka Kripesh Ranjan Sharma Ridip Kumar Sarma Naba Kumar Hazarika Source Type: research
Seasonal predominance of atypical agents in adult community-acquired pneumonia in India's northeastern region: Is it the time to look again at empirical therapy guidelines?
Trop Doct. 2022 Feb 28:494755221080587. doi: 10.1177/00494755221080587. Online ahead of print.ABSTRACTAtypical agents such as Mycoplasma, Legionella, Chlamydia species, and Coxiella burnetii (Q-fever agent) are responsible for some adult community-acquired pneumonia (CAP). Insufficient studies on this topic can be blamed for the failure to include atypical pathogens in empirical management. We followed adult CAP cases for two years, and samples (respiratory and serum) were tested by culture, ELISA (IgM, IgG, and IgA), and PCR. A risk factor analysis was performed. Overall in 21.3% adult CAP patients, atypical agents found ...
Source: Tropical Doctor - February 28, 2022 Category: Tropical Medicine Authors: Deepjyoti Kalita Sangeeta Deka Kripesh Ranjan Sharma Ridip Kumar Sarma Naba Kumar Hazarika Source Type: research
Cancers, Vol. 14, Pages 1005: Current Status of the Spectrum and Therapeutics of Helicobacter pylori-Negative Mucosa-Associated Lymphoid Tissue Lymphoma
Ann-Lii Cheng
Helicobacter pylori (HP)-unrelated mucosa-associated lymphoid tissue (MALT) lymphoma includes the majority of extragastric MALT lymphomas and a small proportion of gastric MALT lymphomas. Although the role of first-line antibiotics in treating HP-negative gastric MALT lymphomas remains controversial, HP eradication therapy (HPE)-like regimens may result in approximately 20–30% complete remission (CR) for patients with localized HP-negative gastric MALT lymphoma. In these patients, H. heilmannii, H. bizzozeronii, and H. suis were detected in sporadic gastric biopsy specimens. Ext...
Source: Cancers - February 16, 2022 Category: Cancer & Oncology Authors: Sung-Hsin Kuo Kun-Huei Yeh Chung-Wu Lin Jyh-Ming Liou Ming-Shiang Wu Li-Tzong Chen Ann-Lii Cheng Tags: Review Source Type: research
The porin AaxA protein model from Chlamydia pneumonia
Bioinformation. 2020 Oct 31;16(10):786-788. doi: 10.6026/97320630016786. eCollection 2020.ABSTRACTChlamydophila pneumoniae is an intracellular pathogen accountable for various acute respiratory infections. C. pneumoniae has a gene cluster which encodes a putative outer membrane porin (aaxA), arginine decarboxylase (CPn1032 or aaxB) and a putative cytoplasmic membrane transporter (CPn1031 or aaxC). Therefore, it is of interest to document a molecular protein model of porin AaxA from Chlamydia pneumonia to gain structure to functional insight on the protein.PMID:34675464 | PMC:PMC8503770 | DOI:10.6026/97320630016786 (Source: Bioinformation)
Source: Bioinformation - October 22, 2021 Category: Bioinformatics Authors: Jayaraman Selvaraj Srinivasan Perumal Josephine Rex Surapaneni Krishna Mohan Sumetha Suga Deiva Suga Umapathy Vidhya Rekh Veeraraghavan Vishnupriya Periyasamy Vijayalakshmi Rajagopal Ponnulakshmi Source Type: research
The porin AaxA protein model from Chlamydia pneumonia
Bioinformation. 2020 Oct 31;16(10):786-788. doi: 10.6026/97320630016786. eCollection 2020.ABSTRACTChlamydophila pneumoniae is an intracellular pathogen accountable for various acute respiratory infections. C. pneumoniae has a gene cluster which encodes a putative outer membrane porin (aaxA), arginine decarboxylase (CPn1032 or aaxB) and a putative cytoplasmic membrane transporter (CPn1031 or aaxC). Therefore, it is of interest to document a molecular protein model of porin AaxA from Chlamydia pneumonia to gain structure to functional insight on the protein.PMID:34675464 | PMC:PMC8503770 | DOI:10.6026/97320630016786 (Source: Bioinformation)
Source: Bioinformation - October 22, 2021 Category: Bioinformatics Authors: Jayaraman Selvaraj Srinivasan Perumal Josephine Rex Surapaneni Krishna Mohan Sumetha Suga Deiva Suga Umapathy Vidhya Rekh Veeraraghavan Vishnupriya Periyasamy Vijayalakshmi Rajagopal Ponnulakshmi Source Type: research
The porin AaxA protein model from Chlamydia pneumonia
Bioinformation. 2020 Oct 31;16(10):786-788. doi: 10.6026/97320630016786. eCollection 2020.ABSTRACTChlamydophila pneumoniae is an intracellular pathogen accountable for various acute respiratory infections. C. pneumoniae has a gene cluster which encodes a putative outer membrane porin (aaxA), arginine decarboxylase (CPn1032 or aaxB) and a putative cytoplasmic membrane transporter (CPn1031 or aaxC). Therefore, it is of interest to document a molecular protein model of porin AaxA from Chlamydia pneumonia to gain structure to functional insight on the protein.PMID:34675464 | PMC:PMC8503770 | DOI:10.6026/97320630016786 (Source: Bioinformation)
Source: Bioinformation - October 22, 2021 Category: Bioinformatics Authors: Jayaraman Selvaraj Srinivasan Perumal Josephine Rex Surapaneni Krishna Mohan Sumetha Suga Deiva Suga Umapathy Vidhya Rekh Veeraraghavan Vishnupriya Periyasamy Vijayalakshmi Rajagopal Ponnulakshmi Source Type: research
The porin AaxA protein model from Chlamydia pneumonia
Bioinformation. 2020 Oct 31;16(10):786-788. doi: 10.6026/97320630016786. eCollection 2020.ABSTRACTChlamydophila pneumoniae is an intracellular pathogen accountable for various acute respiratory infections. C. pneumoniae has a gene cluster which encodes a putative outer membrane porin (aaxA), arginine decarboxylase (CPn1032 or aaxB) and a putative cytoplasmic membrane transporter (CPn1031 or aaxC). Therefore, it is of interest to document a molecular protein model of porin AaxA from Chlamydia pneumonia to gain structure to functional insight on the protein.PMID:34675464 | PMC:PMC8503770 | DOI:10.6026/97320630016786 (Source: Bioinformation)
Source: Bioinformation - October 22, 2021 Category: Bioinformatics Authors: Jayaraman Selvaraj Srinivasan Perumal Josephine Rex Surapaneni Krishna Mohan Sumetha Suga Deiva Suga Umapathy Vidhya Rekh Veeraraghavan Vishnupriya Periyasamy Vijayalakshmi Rajagopal Ponnulakshmi Source Type: research
